---
_id: '6857'
abstract:
- lang: eng
  text: "Gene Drives are regarded as future tools with a high potential for population
    control. Due to their inherent ability to overcome the rules of Mendelian inheritance,
    gene drives (GD) may spread genes rapidly through populations of sexually reproducing
    organisms. A release of organisms carrying a GD would constitute a paradigm shift
    in the handling of genetically modified organisms because gene drive organisms
    (GDO) are designed to drive their transgenes into wild populations and thereby
    increase the number of GDOs. The rapid development in this field and its focus
    on wild populations demand a prospective risk assessment with a focus on exposure
    related aspects. Presently, it is unclear how adequate risk management could be
    guaranteed to limit the spread of GDs in time and space, in order to avoid potential
    adverse effects in socio‐ecological systems.\r\n\r\nThe recent workshop on the
    “Evaluation of Spatial and Temporal Control of Gene Drives” hosted by the Institute
    of Safety/Security and Risk Sciences (ISR) in Vienna aimed at gaining some insight
    into the potential population dynamic behavior of GDs and appropriate measures
    of control. Scientists from France, Germany, England, and the USA discussed both
    topics in this meeting on April 4–5, 2019. This article summarizes results of
    the workshop."
article_number: '1900151'
article_processing_charge: No
article_type: original
author:
- first_name: B
  full_name: Giese, B
  last_name: Giese
- first_name: J L
  full_name: Friess, J L
  last_name: Friess
- first_name: 'M F '
  full_name: 'Schetelig, M F '
  last_name: Schetelig
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Philip
  full_name: Messer, Philip
  last_name: Messer
- first_name: Florence
  full_name: Debarre, Florence
  last_name: Debarre
- first_name: H
  full_name: Meimberg, H
  last_name: Meimberg
- first_name: N
  full_name: Windbichler, N
  last_name: Windbichler
- first_name: C
  full_name: Boete, C
  last_name: Boete
citation:
  ama: 'Giese B, Friess JL, Schetelig MF, et al. Gene Drives: Dynamics and regulatory
    matters – A report from the workshop “Evaluation of spatial and temporal control
    of Gene Drives”, 4 – 5 April 2019, Vienna. <i>BioEssays</i>. 2019;41(11). doi:<a
    href="https://doi.org/10.1002/bies.201900151">10.1002/bies.201900151</a>'
  apa: 'Giese, B., Friess, J. L., Schetelig, M. F., Barton, N. H., Messer, P., Debarre,
    F., … Boete, C. (2019). Gene Drives: Dynamics and regulatory matters – A report
    from the workshop “Evaluation of spatial and temporal control of Gene Drives”,
    4 – 5 April 2019, Vienna. <i>BioEssays</i>. Wiley. <a href="https://doi.org/10.1002/bies.201900151">https://doi.org/10.1002/bies.201900151</a>'
  chicago: 'Giese, B, J L Friess, M F  Schetelig, Nicholas H Barton, Philip Messer,
    Florence Debarre, H Meimberg, N Windbichler, and C Boete. “Gene Drives: Dynamics
    and Regulatory Matters – A Report from the Workshop ‘Evaluation of Spatial and
    Temporal Control of Gene Drives’, 4 – 5 April 2019, Vienna.” <i>BioEssays</i>.
    Wiley, 2019. <a href="https://doi.org/10.1002/bies.201900151">https://doi.org/10.1002/bies.201900151</a>.'
  ieee: 'B. Giese <i>et al.</i>, “Gene Drives: Dynamics and regulatory matters – A
    report from the workshop ‘Evaluation of spatial and temporal control of Gene Drives’,
    4 – 5 April 2019, Vienna,” <i>BioEssays</i>, vol. 41, no. 11. Wiley, 2019.'
  ista: 'Giese B, Friess JL, Schetelig MF, Barton NH, Messer P, Debarre F, Meimberg
    H, Windbichler N, Boete C. 2019. Gene Drives: Dynamics and regulatory matters
    – A report from the workshop “Evaluation of spatial and temporal control of Gene
    Drives”, 4 – 5 April 2019, Vienna. BioEssays. 41(11), 1900151.'
  mla: 'Giese, B., et al. “Gene Drives: Dynamics and Regulatory Matters – A Report
    from the Workshop ‘Evaluation of Spatial and Temporal Control of Gene Drives’,
    4 – 5 April 2019, Vienna.” <i>BioEssays</i>, vol. 41, no. 11, 1900151, Wiley,
    2019, doi:<a href="https://doi.org/10.1002/bies.201900151">10.1002/bies.201900151</a>.'
  short: B. Giese, J.L. Friess, M.F. Schetelig, N.H. Barton, P. Messer, F. Debarre,
    H. Meimberg, N. Windbichler, C. Boete, BioEssays 41 (2019).
date_created: 2019-09-07T14:40:03Z
date_published: 2019-11-01T00:00:00Z
date_updated: 2023-08-30T06:56:26Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1002/bies.201900151
external_id:
  isi:
  - '000489502000001'
file:
- access_level: open_access
  checksum: 8cc7551bff70b2658f8d5630f228ee12
  content_type: application/pdf
  creator: dernst
  date_created: 2019-10-11T06:59:26Z
  date_updated: 2020-07-14T12:47:42Z
  file_id: '6939'
  file_name: 2019_BioEssays_Giese.pdf
  file_size: 193248
  relation: main_file
file_date_updated: 2020-07-14T12:47:42Z
has_accepted_license: '1'
intvolume: '        41'
isi: 1
issue: '11'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: BioEssays
publication_identifier:
  eissn:
  - 1521-1878
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Gene Drives: Dynamics and regulatory matters – A report from the workshop
  “Evaluation of spatial and temporal control of Gene Drives”, 4 – 5 April 2019, Vienna'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 41
year: '2019'
...