---
_id: '4195'
abstract:
- lang: eng
  text: The effects of tri-iodothyronine (T3), which are known to affect cerebellar
    development, were tested on neuronal survival and differentiation of cultured
    cerebellar granule neurons. T3 in physiological concentrations increased both
    granule neuron survival after three days in culture and synaptic vesicle protein
    formation, as shown by immunostaining with antibodies against synaptophysin. Likewise,
    T3 increased the mRNA level for synapsin(I), but not that for GAP43 in granule
    neurons. Antibodies against microtubule associated protein Tau, which is expressed
    in developing neurites, showed that T3 also enhanced neurite formation.
article_processing_charge: No
article_type: original
author:
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
- first_name: Hans
  full_name: Thoenen, Hans
  last_name: Thoenen
- first_name: Dan
  full_name: Lindholm, Dan
  last_name: Lindholm
citation:
  ama: Heisenberg C-PJ, Thoenen H, Lindholm D. Triiodothyronine Regulates Survival
    and Differentiation of Rat Cerebellar Granule Neurons. <i>Neuroreport</i>. 1992;3(8):685-688.
    doi:<a href="https://doi.org/10.1097/00001756-199208000-00008 ">10.1097/00001756-199208000-00008
    </a>
  apa: Heisenberg, C.-P. J., Thoenen, H., &#38; Lindholm, D. (1992). Triiodothyronine
    Regulates Survival and Differentiation of Rat Cerebellar Granule Neurons. <i>Neuroreport</i>.
    Lippincott, Williams &#38; Wilkins. <a href="https://doi.org/10.1097/00001756-199208000-00008
    ">https://doi.org/10.1097/00001756-199208000-00008 </a>
  chicago: Heisenberg, Carl-Philipp J, Hans Thoenen, and Dan Lindholm. “Triiodothyronine
    Regulates Survival and Differentiation of Rat Cerebellar Granule Neurons.” <i>Neuroreport</i>.
    Lippincott, Williams &#38; Wilkins, 1992. <a href="https://doi.org/10.1097/00001756-199208000-00008
    ">https://doi.org/10.1097/00001756-199208000-00008 </a>.
  ieee: C.-P. J. Heisenberg, H. Thoenen, and D. Lindholm, “Triiodothyronine Regulates
    Survival and Differentiation of Rat Cerebellar Granule Neurons,” <i>Neuroreport</i>,
    vol. 3, no. 8. Lippincott, Williams &#38; Wilkins, pp. 685–688, 1992.
  ista: Heisenberg C-PJ, Thoenen H, Lindholm D. 1992. Triiodothyronine Regulates Survival
    and Differentiation of Rat Cerebellar Granule Neurons. Neuroreport. 3(8), 685–688.
  mla: Heisenberg, Carl-Philipp J., et al. “Triiodothyronine Regulates Survival and
    Differentiation of Rat Cerebellar Granule Neurons.” <i>Neuroreport</i>, vol. 3,
    no. 8, Lippincott, Williams &#38; Wilkins, 1992, pp. 685–88, doi:<a href="https://doi.org/10.1097/00001756-199208000-00008
    ">10.1097/00001756-199208000-00008 </a>.
  short: C.-P.J. Heisenberg, H. Thoenen, D. Lindholm, Neuroreport 3 (1992) 685–688.
date_created: 2018-12-11T12:07:31Z
date_published: 1992-01-01T00:00:00Z
date_updated: 2022-03-15T15:25:24Z
day: '01'
doi: '10.1097/00001756-199208000-00008 '
extern: '1'
external_id:
  pmid:
  - '1387811 '
intvolume: '         3'
issue: '8'
language:
- iso: eng
main_file_link:
- url: https://journals.lww.com/neuroreport/abstract/1992/08000/tri_iodothyronine_regulates_survival_and.8.aspx
month: '01'
oa_version: None
page: 685 - 688
pmid: 1
publication: Neuroreport
publication_identifier:
  eissn:
  - 1473-558X
  issn:
  - 0959-4965
publication_status: published
publisher: Lippincott, Williams & Wilkins
publist_id: '1922'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Triiodothyronine Regulates Survival and Differentiation of Rat Cerebellar Granule
  Neurons
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 3
year: '1992'
...