---
_id: '12368'
abstract:
- lang: eng
  text: "Metazoan development relies on the formation and remodeling of cell-cell
    contacts. The \r\nbinding of adhesion receptors and remodeling of the actomyosin
    cell cortex at cell-cell \r\ninteraction sites have been implicated in cell-cell
    contact formation. Yet, how these two \r\nprocesses functionally interact to drive
    cell-cell contact expansion and strengthening \r\nremains unclear. Here, we study
    how primary germ layer progenitor cells from zebrafish \r\nbind to supported lipid
    bilayers (SLB) functionalized with E-cadherin ectodomains as an \r\nassay system
    for monitoring cell-cell contact formation at high spatiotemporal resolution.
    \r\nWe show that cell-cell contact formation represents a two-tiered process:
    E-cadherin\x02mediated downregulation of the small GTPase RhoA at the forming
    contact leads to both \r\ndepletion of Myosin-2 and decrease of F-actin. This
    is followed by centrifugal actin \r\nnetwork flows at the contact triggered by
    a sharp gradient of Myosin-2 at the rim of the \r\ncontact zone, with Myosin-2
    displaying higher cortical localization outside than inside of \r\nthe contact.
    These centrifugal cortical actin flows, in turn, not only further dilute the actin
    \r\nnetwork at the contact disc, but also lead to an accumulation of both F-actin
    and E\x02cadherin at the contact rim. Eventually, this combination of actomyosin
    downregulation \r\nand flows at the contact contribute to the characteristic molecular
    organization implicated \r\nin contact formation and maintenance: depletion of
    cortical actomyosin at the contact disc, \r\ndriving contact expansion by lowering
    interfacial tension at the contact, and accumulation \r\nof both E-cadherin and
    F-actin at the contact rim, mechanically linking the contractile \r\ncortices
    of the adhering cells. Thus, using a biomimetic assay, we exemplify how \r\nadhesion
    signaling and cell mechanics function together to modulate the spatial \r\norganization
    of cell-cell contacts."
acknowledged_ssus:
- _id: LifeSc
- _id: Bio
- _id: NanoFab
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Feyza N
  full_name: Arslan, Feyza N
  id: 49DA7910-F248-11E8-B48F-1D18A9856A87
  last_name: Arslan
  orcid: 0000-0001-5809-9566
citation:
  ama: Arslan FN. Remodeling of E-cadherin-mediated contacts via cortical  flows.
    2022. doi:<a href="https://doi.org/10.15479/at:ista:12153">10.15479/at:ista:12153</a>
  apa: Arslan, F. N. (2022). <i>Remodeling of E-cadherin-mediated contacts via cortical 
    flows</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:12153">https://doi.org/10.15479/at:ista:12153</a>
  chicago: Arslan, Feyza N. “Remodeling of E-Cadherin-Mediated Contacts via Cortical 
    Flows.” Institute of Science and Technology Austria, 2022. <a href="https://doi.org/10.15479/at:ista:12153">https://doi.org/10.15479/at:ista:12153</a>.
  ieee: F. N. Arslan, “Remodeling of E-cadherin-mediated contacts via cortical  flows,”
    Institute of Science and Technology Austria, 2022.
  ista: Arslan FN. 2022. Remodeling of E-cadherin-mediated contacts via cortical 
    flows. Institute of Science and Technology Austria.
  mla: Arslan, Feyza N. <i>Remodeling of E-Cadherin-Mediated Contacts via Cortical 
    Flows</i>. Institute of Science and Technology Austria, 2022, doi:<a href="https://doi.org/10.15479/at:ista:12153">10.15479/at:ista:12153</a>.
  short: F.N. Arslan, Remodeling of E-Cadherin-Mediated Contacts via Cortical  Flows,
    Institute of Science and Technology Austria, 2022.
date_created: 2023-01-25T10:43:24Z
date_published: 2022-09-29T00:00:00Z
date_updated: 2023-08-08T13:14:10Z
day: '29'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: CaHe
doi: 10.15479/at:ista:12153
ec_funded: 1
file:
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  checksum: e54a3e69b83ebf166544164afd25608e
  content_type: application/pdf
  creator: cchlebak
  date_created: 2023-01-25T10:52:46Z
  date_updated: 2023-01-25T10:52:46Z
  file_id: '12369'
  file_name: THESIS_FINAL_FArslan_pdfa.pdf
  file_size: 14581024
  relation: main_file
  success: 1
file_date_updated: 2023-01-25T10:52:46Z
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '113'
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742573'
  name: Interaction and feedback between cell mechanics and fate specification in
    vertebrate gastrulation
publication_identifier:
  isbn:
  - ' 978-3-99078-025-1 '
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '9350'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
title: Remodeling of E-cadherin-mediated contacts via cortical  flows
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '12378'
abstract:
- lang: eng
  text: "Environmental cues influence the highly dynamic morphology of microglia.
    Strategies to \r\ncharacterize these changes usually involve user-selected morphometric
    features, which \r\npreclude the identification of a spectrum of context-dependent
    morphological phenotypes. \r\nHere, we develop MorphOMICs, a topological data
    analysis approach, which enables semi\x02automatic mapping of microglial morphology
    into an atlas of cue-dependent phenotypes,\r\novercomes feature-selection bias
    and minimizes biological variability. \r\nFirst, with MorphOMICs we derive the
    morphological spectrum of microglia across seven \r\nbrain regions during postnatal
    development and in two distinct Alzheimer’s disease \r\ndegeneration mouse models.
    We uncover region-specific and sexually dimorphic\r\nmorphological trajectories,
    with females showing an earlier morphological shift than males in \r\nthe degenerating
    brain. Overall, we demonstrate that both long primary- and short terminal \r\nprocesses
    provide distinct insights to morphological phenotypes. Moreover, using machine
    \r\nlearning to map novel condition on the spectrum, we observe that microglia
    morphologies \r\nreflect a dose-dependent adaptation upon ketamine anesthesia
    and do not recover to control \r\nmorphologies.\r\nNext, we took advantage of
    MorphOMICs to build a high-resolution and layer-specific map of \r\nmicroglial
    morphological spectrum in the retina, covering postnatal development and rd10
    \r\ndegeneration. Here, following photoreceptor death, microglia assume an early
    development\x02like morphology. Finally, we map microglial morphology following
    optic nerve crush on the \r\nretinal spectrum and observe a layer- and sex-dependent
    response. \r\nOverall, MorphOMICs opens a new perspective to analyze microglial
    morphology across \r\nmultiple conditions, and provides a novel tool to characterize
    microglial morphology beyond \r\nthe traditionally dichotomized view of microglia."
acknowledged_ssus:
- _id: PreCl
- _id: Bio
- _id: ScienComp
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Gloria
  full_name: Colombo, Gloria
  id: 3483CF6C-F248-11E8-B48F-1D18A9856A87
  last_name: Colombo
  orcid: 0000-0001-9434-8902
citation:
  ama: Colombo G. MorphOMICs, a tool for mapping microglial morphology, reveals brain
    region- and sex-dependent phenotypes. 2022. doi:<a href="https://doi.org/10.15479/at:ista:12378">10.15479/at:ista:12378</a>
  apa: Colombo, G. (2022). <i>MorphOMICs, a tool for mapping microglial morphology,
    reveals brain region- and sex-dependent phenotypes</i>. Institute of Science and
    Technology Austria. <a href="https://doi.org/10.15479/at:ista:12378">https://doi.org/10.15479/at:ista:12378</a>
  chicago: Colombo, Gloria. “MorphOMICs, a Tool for Mapping Microglial Morphology,
    Reveals Brain Region- and Sex-Dependent Phenotypes.” Institute of Science and
    Technology Austria, 2022. <a href="https://doi.org/10.15479/at:ista:12378">https://doi.org/10.15479/at:ista:12378</a>.
  ieee: G. Colombo, “MorphOMICs, a tool for mapping microglial morphology, reveals
    brain region- and sex-dependent phenotypes,” Institute of Science and Technology
    Austria, 2022.
  ista: Colombo G. 2022. MorphOMICs, a tool for mapping microglial morphology, reveals
    brain region- and sex-dependent phenotypes. Institute of Science and Technology
    Austria.
  mla: Colombo, Gloria. <i>MorphOMICs, a Tool for Mapping Microglial Morphology, Reveals
    Brain Region- and Sex-Dependent Phenotypes</i>. Institute of Science and Technology
    Austria, 2022, doi:<a href="https://doi.org/10.15479/at:ista:12378">10.15479/at:ista:12378</a>.
  short: G. Colombo, MorphOMICs, a Tool for Mapping Microglial Morphology, Reveals
    Brain Region- and Sex-Dependent Phenotypes, Institute of Science and Technology
    Austria, 2022.
date_created: 2023-01-25T14:27:43Z
date_published: 2022-11-11T00:00:00Z
date_updated: 2023-08-04T09:40:37Z
day: '11'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: SaSi
doi: 10.15479/at:ista:12378
ec_funded: 1
file:
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  checksum: 8cd3ddfe9b53381dcf086023d8d8893a
  content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
  creator: cchlebak
  date_created: 2023-01-25T14:31:32Z
  date_updated: 2023-04-12T22:30:03Z
  embargo_to: open_access
  file_id: '12379'
  file_name: Gloria_Colombo_Thesis.docx
  file_size: 23890382
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  date_created: 2023-01-25T14:31:36Z
  date_updated: 2023-04-12T22:30:03Z
  embargo: 2023-04-11
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  relation: main_file
file_date_updated: 2023-04-12T22:30:03Z
has_accepted_license: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: '142'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '12244'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Sandra
  full_name: Siegert, Sandra
  id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
  last_name: Siegert
  orcid: 0000-0001-8635-0877
title: MorphOMICs, a tool for mapping microglial morphology, reveals brain region-
  and sex-dependent phenotypes
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '12390'
abstract:
- lang: eng
  text: "The scope of this thesis is to study quantum systems exhibiting a continuous
    symmetry that\r\nis broken on the level of the corresponding effective theory.
    In particular we are going to\r\ninvestigate translation-invariant Bose gases
    in the mean field limit, effectively described by\r\nthe Hartree functional, and
    the Fröhlich Polaron in the regime of strong coupling, effectively\r\ndescribed
    by the Pekar functional. The latter is a model describing the interaction between
    a\r\ncharged particle and the optical modes of a polar crystal. Regarding the
    former, we assume in\r\naddition that the particles in the gas are unconfined,
    and typically we will consider particles\r\nthat are subject to an attractive
    interaction. In both cases the ground state energy of the\r\nHamiltonian is not
    a proper eigenvalue due to the underlying translation-invariance, while on\r\nthe
    contrary there exists a whole invariant orbit of minimizers for the corresponding
    effective\r\nfunctionals. Both, the absence of proper eigenstates and the broken
    symmetry of the effective\r\ntheory, make the study significantly more involved
    and it is the content of this thesis to\r\ndevelop a frameworks which allows for
    a systematic way to circumvent these issues.\r\nIt is a well-established result
    that the ground state energy of Bose gases in the mean field limit,\r\nas well
    as the ground state energy of the Fröhlich Polaron in the regime of strong coupling,
    is\r\nto leading order given by the minimal energy of the corresponding effective
    theory. As part\r\nof this thesis we identify the sub-leading term in the expansion
    of the ground state energy,\r\nwhich can be interpreted as the quantum correction
    to the classical energy, since the effective\r\ntheories under consideration can
    be seen as classical counterparts.\r\nWe are further going to establish an asymptotic
    expression for the energy-momentum relation\r\nof the Fröhlich Polaron in the
    strong coupling limit. In the regime of suitably small momenta,\r\nthis asymptotic
    expression agrees with the energy-momentum relation of a free particle having\r\nan
    effectively increased mass, and we find that this effectively increased mass agrees
    with the\r\nconjectured value in the physics literature.\r\nIn addition we will
    discuss two unrelated papers written by the author during his stay at ISTA\r\nin
    the appendix. The first one concerns the realization of anyons, which are quasi-particles\r\nacquiring
    a non-trivial phase under the exchange of two particles, as molecular impurities.\r\nThe
    second one provides a classification of those vector fields defined on a given
    manifold\r\nthat can be written as the gradient of a given functional with respect
    to a suitable metric,\r\nprovided that some mild smoothness assumptions hold.
    This classification is subsequently\r\nused to identify those quantum Markov semigroups
    that can be written as a gradient flow of\r\nthe relative entropy.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Morris
  full_name: Brooks, Morris
  id: B7ECF9FC-AA38-11E9-AC9A-0930E6697425
  last_name: Brooks
  orcid: 0000-0002-6249-0928
citation:
  ama: Brooks M. Translation-invariant quantum systems with effectively broken symmetry.
    2022. doi:<a href="https://doi.org/10.15479/at:ista:12390">10.15479/at:ista:12390</a>
  apa: Brooks, M. (2022). <i>Translation-invariant quantum systems with effectively
    broken symmetry</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:12390">https://doi.org/10.15479/at:ista:12390</a>
  chicago: Brooks, Morris. “Translation-Invariant Quantum Systems with Effectively
    Broken Symmetry.” Institute of Science and Technology Austria, 2022. <a href="https://doi.org/10.15479/at:ista:12390">https://doi.org/10.15479/at:ista:12390</a>.
  ieee: M. Brooks, “Translation-invariant quantum systems with effectively broken
    symmetry,” Institute of Science and Technology Austria, 2022.
  ista: Brooks M. 2022. Translation-invariant quantum systems with effectively broken
    symmetry. Institute of Science and Technology Austria.
  mla: Brooks, Morris. <i>Translation-Invariant Quantum Systems with Effectively Broken
    Symmetry</i>. Institute of Science and Technology Austria, 2022, doi:<a href="https://doi.org/10.15479/at:ista:12390">10.15479/at:ista:12390</a>.
  short: M. Brooks, Translation-Invariant Quantum Systems with Effectively Broken
    Symmetry, Institute of Science and Technology Austria, 2022.
date_created: 2023-01-26T10:00:42Z
date_published: 2022-12-15T00:00:00Z
date_updated: 2023-08-07T13:32:09Z
day: '15'
ddc:
- '500'
degree_awarded: PhD
department:
- _id: GradSch
- _id: RoSe
doi: 10.15479/at:ista:12390
ec_funded: 1
file:
- access_level: open_access
  checksum: b31460e937f33b557abb40ebef02b567
  content_type: application/pdf
  creator: cchlebak
  date_created: 2023-01-26T10:02:34Z
  date_updated: 2023-01-26T10:02:34Z
  file_id: '12391'
  file_name: Brooks_Thesis.pdf
  file_size: 3095225
  relation: main_file
  success: 1
- access_level: closed
  checksum: 9751869fa5e7981588ad4228f4fd4bd6
  content_type: application/octet-stream
  creator: cchlebak
  date_created: 2023-01-26T10:02:42Z
  date_updated: 2023-01-26T10:02:42Z
  file_id: '12392'
  file_name: Brooks_Thesis.tex
  file_size: 809842
  relation: source_file
file_date_updated: 2023-01-26T10:02:42Z
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '12'
oa: 1
oa_version: Published Version
page: '196'
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694227'
  name: Analysis of quantum many-body systems
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '9005'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
title: Translation-invariant quantum systems with effectively broken symmetry
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2022'
...
---
_id: '12401'
abstract:
- lang: eng
  text: "Detachment of the cancer cells from the bulk of the tumor is the first step
    of metastasis, which\r\nis the primary cause of cancer related deaths. It is unclear,
    which factors contribute to this step.\r\nRecent studies indicate a crucial role
    of the tumor microenvironment in malignant\r\ntransformation and metastasis. Studying
    cancer cell invasion and detachments quantitatively in\r\nthe context of its physiological
    microenvironment is technically challenging. Especially, precise\r\ncontrol of
    microenvironmental properties in vivo is currently not possible. Here, I studied
    the\r\nrole of microenvironment geometry in the invasion and detachment of cancer
    cells from the\r\nbulk with a simplistic and reductionist approach. In this approach,
    I engineered microfluidic\r\ndevices to mimic a pseudo 3D extracellular matrix
    environment, where I was able to\r\nquantitatively tune the geometrical configuration
    of the microenvironment and follow tumor\r\ncells with fluorescence live imaging.
    To aid quantitative analysis I developed a widely applicable\r\nsoftware application
    to automatically analyze and visualize particle tracking data.\r\nQuantitative
    analysis of tumor cell invasion in isotropic and anisotropic microenvironments\r\nshowed
    that heterogeneity in the microenvironment promotes faster invasion and more\r\nfrequent
    detachment of cells. These observations correlated with overall higher speed of
    cells at\r\nthe edge of the bulk of the cells. In heterogeneous microenvironments
    cells preferentially\r\npassed through larger pores, thus invading areas of least
    resistance and generating finger-like\r\ninvasive structures. The detachments
    occurred mostly at the tips of these structures.\r\nTo investigate the potential
    mechanism, we established a two dimensional model to simulate\r\nactive Brownian
    particles representing the cell nuclei dynamics. These simulations backed our
    in\r\nvitro observations without the need of precise fitting the simulation parameters.
    Our model\r\nsuggests the importance of the pore heterogeneity in the direction
    perpendicular to the\r\norientation of bias field (lateral heterogeneity), which
    causes the interface roughening."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Saren
  full_name: Tasciyan, Saren
  id: 4323B49C-F248-11E8-B48F-1D18A9856A87
  last_name: Tasciyan
  orcid: 0000-0003-1671-393X
citation:
  ama: Tasciyan S. Role of microenvironment heterogeneity in cancer cell invasion.
    2022. doi:<a href="https://doi.org/10.15479/at:ista:12401">10.15479/at:ista:12401</a>
  apa: Tasciyan, S. (2022). <i>Role of microenvironment heterogeneity in cancer cell
    invasion</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:12401">https://doi.org/10.15479/at:ista:12401</a>
  chicago: Tasciyan, Saren. “Role of Microenvironment Heterogeneity in Cancer Cell
    Invasion.” Institute of Science and Technology Austria, 2022. <a href="https://doi.org/10.15479/at:ista:12401">https://doi.org/10.15479/at:ista:12401</a>.
  ieee: S. Tasciyan, “Role of microenvironment heterogeneity in cancer cell invasion,”
    Institute of Science and Technology Austria, 2022.
  ista: Tasciyan S. 2022. Role of microenvironment heterogeneity in cancer cell invasion.
    Institute of Science and Technology Austria.
  mla: Tasciyan, Saren. <i>Role of Microenvironment Heterogeneity in Cancer Cell Invasion</i>.
    Institute of Science and Technology Austria, 2022, doi:<a href="https://doi.org/10.15479/at:ista:12401">10.15479/at:ista:12401</a>.
  short: S. Tasciyan, Role of Microenvironment Heterogeneity in Cancer Cell Invasion,
    Institute of Science and Technology Austria, 2022.
date_created: 2023-01-26T11:55:16Z
date_published: 2022-12-22T00:00:00Z
date_updated: 2024-09-10T12:04:26Z
day: '22'
ddc:
- '610'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MiSi
doi: 10.15479/at:ista:12401
file:
- access_level: open_access
  checksum: cc4a2b4a7e3c4ee8ef7f2dbf909b12bd
  content_type: application/pdf
  creator: cchlebak
  date_created: 2023-01-26T11:58:14Z
  date_updated: 2023-12-21T23:30:03Z
  embargo: 2023-12-20
  file_id: '12402'
  file_name: PhD-Thesis_Saren Tasciyan_formatted_aftercrash_fixed_600dpi_95pc_final_PDFA3b.pdf
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  relation: main_file
- access_level: closed
  checksum: f1b4ca98b8ab0cb043b1830971e9bd9c
  content_type: application/x-zip-compressed
  creator: cchlebak
  date_created: 2023-01-26T12:00:10Z
  date_updated: 2023-12-21T23:30:03Z
  embargo_to: open_access
  file_id: '12403'
  file_name: Source Files - Saren Tasciyan - PhD Thesis.zip
  file_size: 261256696
  relation: source_file
file_date_updated: 2023-12-21T23:30:03Z
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: '105'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '679'
    relation: part_of_dissertation
    status: public
  - id: '10703'
    relation: part_of_dissertation
    status: public
  - id: '7885'
    relation: part_of_dissertation
    status: public
  - id: '9429'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
title: Role of microenvironment heterogeneity in cancer cell invasion
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2022'
...
---
_id: '12677'
abstract:
- lang: eng
  text: "In modern sample-driven Prophet Inequality, an adversary chooses a sequence
    of n items with values v1,v2,…,vn to be presented to a decision maker (DM). The
    process follows in two phases. In the first phase (sampling phase), some items,
    possibly selected at random, are revealed to the DM, but she can never accept
    them. In the second phase, the DM is presented with the other items in a random
    order and online fashion. For each item, she must make an irrevocable decision
    to either accept the item and stop the process or reject the item forever and
    proceed to the next item. The goal of the DM is to maximize the expected value
    as compared to a Prophet (or offline algorithm) that has access to all information.
    In this setting, the sampling phase has no cost and is not part of the optimization
    process. However, in many scenarios, the samples are obtained as part of the decision-making
    process.\r\nWe model this aspect as a two-phase Prophet Inequality where an adversary
    chooses a sequence of 2n items with values v1,v2,…,v2n and the items are randomly
    ordered. Finally, there are two phases of the Prophet Inequality problem with
    the first n-items and the rest of the items, respectively. We show that some basic
    algorithms achieve a ratio of at most 0.450. We present an algorithm that achieves
    a ratio of at least 0.495. Finally, we show that for every algorithm the ratio
    it can achieve is at most 0.502. Hence our algorithm is near-optimal."
acknowledgement: This research was partially supported by the ERC CoG 863818 (ForM-SMArt)
  grant.
article_number: '2209.14368'
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Mona
  full_name: Mohammadi, Mona
  id: 4363614d-b686-11ed-a7d5-ac9e4a24bc2e
  last_name: Mohammadi
- first_name: Raimundo J
  full_name: Saona Urmeneta, Raimundo J
  id: BD1DF4C4-D767-11E9-B658-BC13E6697425
  last_name: Saona Urmeneta
  orcid: 0000-0001-5103-038X
citation:
  ama: Chatterjee K, Mohammadi M, Saona Urmeneta RJ. Repeated prophet inequality with
    near-optimal bounds. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/ARXIV.2209.14368">10.48550/ARXIV.2209.14368</a>
  apa: Chatterjee, K., Mohammadi, M., &#38; Saona Urmeneta, R. J. (n.d.). Repeated
    prophet inequality with near-optimal bounds. <i>arXiv</i>. <a href="https://doi.org/10.48550/ARXIV.2209.14368">https://doi.org/10.48550/ARXIV.2209.14368</a>
  chicago: Chatterjee, Krishnendu, Mona Mohammadi, and Raimundo J Saona Urmeneta.
    “Repeated Prophet Inequality with Near-Optimal Bounds.” <i>ArXiv</i>, n.d. <a
    href="https://doi.org/10.48550/ARXIV.2209.14368">https://doi.org/10.48550/ARXIV.2209.14368</a>.
  ieee: K. Chatterjee, M. Mohammadi, and R. J. Saona Urmeneta, “Repeated prophet inequality
    with near-optimal bounds,” <i>arXiv</i>. .
  ista: Chatterjee K, Mohammadi M, Saona Urmeneta RJ. Repeated prophet inequality
    with near-optimal bounds. arXiv, 2209.14368.
  mla: Chatterjee, Krishnendu, et al. “Repeated Prophet Inequality with Near-Optimal
    Bounds.” <i>ArXiv</i>, 2209.14368, doi:<a href="https://doi.org/10.48550/ARXIV.2209.14368">10.48550/ARXIV.2209.14368</a>.
  short: K. Chatterjee, M. Mohammadi, R.J. Saona Urmeneta, ArXiv (n.d.).
date_created: 2023-02-24T12:21:40Z
date_published: 2022-09-28T00:00:00Z
date_updated: 2025-07-14T09:09:51Z
day: '28'
department:
- _id: GradSch
- _id: KrCh
doi: 10.48550/ARXIV.2209.14368
ec_funded: 1
external_id:
  arxiv:
  - '2209.14368'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.2209.14368'
month: '09'
oa: 1
oa_version: Preprint
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: arXiv
publication_status: submitted
status: public
title: Repeated prophet inequality with near-optimal bounds
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '12750'
abstract:
- lang: eng
  text: Quantum kinetically constrained models have recently attracted significant
    attention due to their anomalous dynamics and thermalization. In this work, we
    introduce a hitherto unexplored family of kinetically constrained models featuring
    a conserved particle number and strong inversion-symmetry breaking due to facilitated
    hopping. We demonstrate that these models provide a generic example of so-called
    quantum Hilbert space fragmentation, that is manifested in disconnected sectors
    in the Hilbert space that are not apparent in the computational basis. Quantum
    Hilbert space fragmentation leads to an exponential in system size number of eigenstates
    with exactly zero entanglement entropy across several bipartite cuts. These eigenstates
    can be probed dynamically using quenches from simple initial product states. In
    addition, we study the particle spreading under unitary dynamics launched from
    the domain wall state, and find faster than diffusive dynamics at high particle
    densities, that crosses over into logarithmically slow relaxation at smaller densities.
    Using a classically simulable cellular automaton, we reproduce the logarithmic
    dynamics observed in the quantum case. Our work suggests that particle conserving
    constrained models with inversion symmetry breaking realize so far unexplored
    universality classes of dynamics and invite their further theoretical and experimental
    studies.
article_number: '2210.15607'
article_processing_charge: No
arxiv: 1
author:
- first_name: Pietro
  full_name: Brighi, Pietro
  id: 4115AF5C-F248-11E8-B48F-1D18A9856A87
  last_name: Brighi
  orcid: 0000-0002-7969-2729
- first_name: Marko
  full_name: Ljubotina, Marko
  id: F75EE9BE-5C90-11EA-905D-16643DDC885E
  last_name: Ljubotina
  orcid: 0000-0003-0038-7068
- first_name: Maksym
  full_name: Serbyn, Maksym
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
citation:
  ama: Brighi P, Ljubotina M, Serbyn M. Hilbert space fragmentation and slow dynamics
    in particle-conserving quantum East models. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/arXiv.2210.15607">10.48550/arXiv.2210.15607</a>
  apa: Brighi, P., Ljubotina, M., &#38; Serbyn, M. (n.d.). Hilbert space fragmentation
    and slow dynamics in particle-conserving quantum East models. <i>arXiv</i>. <a
    href="https://doi.org/10.48550/arXiv.2210.15607">https://doi.org/10.48550/arXiv.2210.15607</a>
  chicago: Brighi, Pietro, Marko Ljubotina, and Maksym Serbyn. “Hilbert Space Fragmentation
    and Slow Dynamics in Particle-Conserving Quantum East Models.” <i>ArXiv</i>, n.d.
    <a href="https://doi.org/10.48550/arXiv.2210.15607">https://doi.org/10.48550/arXiv.2210.15607</a>.
  ieee: P. Brighi, M. Ljubotina, and M. Serbyn, “Hilbert space fragmentation and slow
    dynamics in particle-conserving quantum East models,” <i>arXiv</i>. .
  ista: Brighi P, Ljubotina M, Serbyn M. Hilbert space fragmentation and slow dynamics
    in particle-conserving quantum East models. arXiv, 2210.15607.
  mla: Brighi, Pietro, et al. “Hilbert Space Fragmentation and Slow Dynamics in Particle-Conserving
    Quantum East Models.” <i>ArXiv</i>, 2210.15607, doi:<a href="https://doi.org/10.48550/arXiv.2210.15607">10.48550/arXiv.2210.15607</a>.
  short: P. Brighi, M. Ljubotina, M. Serbyn, ArXiv (n.d.).
date_created: 2023-03-23T14:33:13Z
date_published: 2022-11-07T00:00:00Z
date_updated: 2023-09-20T10:46:29Z
day: '07'
department:
- _id: GradSch
- _id: MaSe
doi: 10.48550/arXiv.2210.15607
external_id:
  arxiv:
  - '2210.15607'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2210.15607
month: '11'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: submitted
related_material:
  record:
  - id: '12732'
    relation: dissertation_contains
    status: public
  - id: '14334'
    relation: later_version
    status: public
status: public
title: Hilbert space fragmentation and slow dynamics in particle-conserving quantum
  East models
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '12860'
abstract:
- lang: eng
  text: 'Memorization of the relation between entities in a dataset can lead to privacy
    issues when using a trained model for question answering. We introduce Relational
    Memorization (RM) to understand, quantify and control this phenomenon. While bounding
    general memorization can have detrimental effects on the performance of a trained
    model, bounding RM does not prevent effective learning. The difference is most
    pronounced when the data distribution is long-tailed, with many queries having
    only few training examples: Impeding general memorization prevents effective learning,
    while impeding only relational memorization still allows learning general properties
    of the underlying concepts. We formalize the notion of Relational Privacy (RP)
    and, inspired by Differential Privacy (DP), we provide a possible definition of
    Differential Relational Privacy (DrP). These notions can be used to describe and
    compute bounds on the amount of RM in a trained model. We illustrate Relational
    Privacy concepts in experiments with large-scale models for Question Answering.'
article_number: '2203.16701'
article_processing_charge: No
arxiv: 1
author:
- first_name: Simone
  full_name: Bombari, Simone
  id: ca726dda-de17-11ea-bc14-f9da834f63aa
  last_name: Bombari
- first_name: Alessandro
  full_name: Achille, Alessandro
  last_name: Achille
- first_name: Zijian
  full_name: Wang, Zijian
  last_name: Wang
- first_name: Yu-Xiang
  full_name: Wang, Yu-Xiang
  last_name: Wang
- first_name: Yusheng
  full_name: Xie, Yusheng
  last_name: Xie
- first_name: Kunwar Yashraj
  full_name: Singh, Kunwar Yashraj
  last_name: Singh
- first_name: Srikar
  full_name: Appalaraju, Srikar
  last_name: Appalaraju
- first_name: Vijay
  full_name: Mahadevan, Vijay
  last_name: Mahadevan
- first_name: Stefano
  full_name: Soatto, Stefano
  last_name: Soatto
citation:
  ama: Bombari S, Achille A, Wang Z, et al. Towards differential relational privacy
    and its use in question answering. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/arXiv.2203.16701">10.48550/arXiv.2203.16701</a>
  apa: Bombari, S., Achille, A., Wang, Z., Wang, Y.-X., Xie, Y., Singh, K. Y., … Soatto,
    S. (n.d.). Towards differential relational privacy and its use in question answering.
    <i>arXiv</i>. <a href="https://doi.org/10.48550/arXiv.2203.16701">https://doi.org/10.48550/arXiv.2203.16701</a>
  chicago: Bombari, Simone, Alessandro Achille, Zijian Wang, Yu-Xiang Wang, Yusheng
    Xie, Kunwar Yashraj Singh, Srikar Appalaraju, Vijay Mahadevan, and Stefano Soatto.
    “Towards Differential Relational Privacy and Its Use in Question Answering.” <i>ArXiv</i>,
    n.d. <a href="https://doi.org/10.48550/arXiv.2203.16701">https://doi.org/10.48550/arXiv.2203.16701</a>.
  ieee: S. Bombari <i>et al.</i>, “Towards differential relational privacy and its
    use in question answering,” <i>arXiv</i>. .
  ista: Bombari S, Achille A, Wang Z, Wang Y-X, Xie Y, Singh KY, Appalaraju S, Mahadevan
    V, Soatto S. Towards differential relational privacy and its use in question answering.
    arXiv, 2203.16701.
  mla: Bombari, Simone, et al. “Towards Differential Relational Privacy and Its Use
    in Question Answering.” <i>ArXiv</i>, 2203.16701, doi:<a href="https://doi.org/10.48550/arXiv.2203.16701">10.48550/arXiv.2203.16701</a>.
  short: S. Bombari, A. Achille, Z. Wang, Y.-X. Wang, Y. Xie, K.Y. Singh, S. Appalaraju,
    V. Mahadevan, S. Soatto, ArXiv (n.d.).
date_created: 2023-04-23T16:11:48Z
date_published: 2022-03-30T00:00:00Z
date_updated: 2023-04-25T07:34:49Z
day: '30'
department:
- _id: GradSch
- _id: MaMo
doi: 10.48550/arXiv.2203.16701
external_id:
  arxiv:
  - '2203.16701'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2203.16701
month: '03'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: submitted
status: public
title: Towards differential relational privacy and its use in question answering
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '9311'
abstract:
- lang: eng
  text: 'Partially observable Markov decision processes (POMDPs) are standard models
    for dynamic systems with probabilistic and nondeterministic behaviour in uncertain
    environments. We prove that in POMDPs with long-run average objective, the decision
    maker has approximately optimal strategies with finite memory. This implies notably
    that approximating the long-run value is recursively enumerable, as well as a
    weak continuity property of the value with respect to the transition function. '
acknowledgement: "Partially supported by Austrian Science Fund (FWF) NFN Grant No
  RiSE/SHiNE S11407, by CONICYT Chile through grant PII 20150140, and by ECOS-CONICYT
  through grant C15E03.\r\n"
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Raimundo J
  full_name: Saona Urmeneta, Raimundo J
  id: BD1DF4C4-D767-11E9-B658-BC13E6697425
  last_name: Saona Urmeneta
  orcid: 0000-0001-5103-038X
- first_name: Bruno
  full_name: Ziliotto, Bruno
  last_name: Ziliotto
citation:
  ama: Chatterjee K, Saona Urmeneta RJ, Ziliotto B. Finite-memory strategies in POMDPs
    with long-run average objectives. <i>Mathematics of Operations Research</i>. 2022;47(1):100-119.
    doi:<a href="https://doi.org/10.1287/moor.2020.1116">10.1287/moor.2020.1116</a>
  apa: Chatterjee, K., Saona Urmeneta, R. J., &#38; Ziliotto, B. (2022). Finite-memory
    strategies in POMDPs with long-run average objectives. <i>Mathematics of Operations
    Research</i>. Institute for Operations Research and the Management Sciences. <a
    href="https://doi.org/10.1287/moor.2020.1116">https://doi.org/10.1287/moor.2020.1116</a>
  chicago: Chatterjee, Krishnendu, Raimundo J Saona Urmeneta, and Bruno Ziliotto.
    “Finite-Memory Strategies in POMDPs with Long-Run Average Objectives.” <i>Mathematics
    of Operations Research</i>. Institute for Operations Research and the Management
    Sciences, 2022. <a href="https://doi.org/10.1287/moor.2020.1116">https://doi.org/10.1287/moor.2020.1116</a>.
  ieee: K. Chatterjee, R. J. Saona Urmeneta, and B. Ziliotto, “Finite-memory strategies
    in POMDPs with long-run average objectives,” <i>Mathematics of Operations Research</i>,
    vol. 47, no. 1. Institute for Operations Research and the Management Sciences,
    pp. 100–119, 2022.
  ista: Chatterjee K, Saona Urmeneta RJ, Ziliotto B. 2022. Finite-memory strategies
    in POMDPs with long-run average objectives. Mathematics of Operations Research.
    47(1), 100–119.
  mla: Chatterjee, Krishnendu, et al. “Finite-Memory Strategies in POMDPs with Long-Run
    Average Objectives.” <i>Mathematics of Operations Research</i>, vol. 47, no. 1,
    Institute for Operations Research and the Management Sciences, 2022, pp. 100–19,
    doi:<a href="https://doi.org/10.1287/moor.2020.1116">10.1287/moor.2020.1116</a>.
  short: K. Chatterjee, R.J. Saona Urmeneta, B. Ziliotto, Mathematics of Operations
    Research 47 (2022) 100–119.
date_created: 2021-04-08T09:33:31Z
date_published: 2022-02-01T00:00:00Z
date_updated: 2023-09-05T13:16:11Z
day: '01'
department:
- _id: GradSch
- _id: KrCh
doi: 10.1287/moor.2020.1116
external_id:
  arxiv:
  - '1904.13360'
  isi:
  - '000731918100001'
intvolume: '        47'
isi: 1
issue: '1'
keyword:
- Management Science and Operations Research
- General Mathematics
- Computer Science Applications
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1904.13360
month: '02'
oa: 1
oa_version: Preprint
page: 100-119
project:
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
publication: Mathematics of Operations Research
publication_identifier:
  eissn:
  - 1526-5471
  issn:
  - 0364-765X
publication_status: published
publisher: Institute for Operations Research and the Management Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Finite-memory strategies in POMDPs with long-run average objectives
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 47
year: '2022'
...
---
_id: '14355'
abstract:
- lang: eng
  text: 'Purpose: The mediator (MED) multisubunit-complex modulates the activity of
    the transcriptional machinery, and genetic defects in different MED subunits (17,
    20, 27) have been implicated in neurologic diseases. In this study, we identified
    a recurrent homozygous variant in MED11 (c.325C>T; p.Arg109Ter) in 7 affected
    individuals from 5 unrelated families. Methods: To investigate the genetic cause
    of the disease, exome or genome sequencing were performed in 5 unrelated families
    identified via different research networks and Matchmaker Exchange. Deep clinical
    and brain imaging evaluations were performed by clinical pediatric neurologists
    and neuroradiologists. The functional effect of the candidate variant on both
    MED11 RNA and protein was assessed using reverse transcriptase polymerase chain
    reaction and western blotting using fibroblast cell lines derived from 1 affected
    individual and controls and through computational approaches. Knockouts in zebrafish
    were generated using clustered regularly interspaced short palindromic repeats/Cas9.
    Results: The disease was characterized by microcephaly, profound neurodevelopmental
    impairment, exaggerated startle response, myoclonic seizures, progressive widespread
    neurodegeneration, and premature death. Functional studies on patient-derived
    fibroblasts did not show a loss of protein function but rather disruption of the
    C-terminal of MED11, likely impairing binding to other MED subunits. A zebrafish
    knockout model recapitulates key clinical phenotypes. Conclusion: Loss of the
    C-terminal of MED subunit 11 may affect its binding efficiency to other MED subunits,
    thus implicating the MED-complex stability in brain development and neurodegeneration.
    (C) 2022 The Authors. Published by Elsevier Inc. on behalf of American College
    of Medical Genetics and Genomics.'
article_processing_charge: No
article_type: original
author:
- first_name: Elisa
  full_name: Cali, Elisa
  last_name: Cali
- first_name: Sheng-Jia
  full_name: Lin, Sheng-Jia
  last_name: Lin
- first_name: Clarissa
  full_name: Rocca, Clarissa
  last_name: Rocca
- first_name: Yavuz
  full_name: Sahin, Yavuz
  last_name: Sahin
- first_name: Aisha
  full_name: Al Shamsi, Aisha
  last_name: Al Shamsi
- first_name: Salima
  full_name: El Chehadeh, Salima
  last_name: El Chehadeh
- first_name: Myriam
  full_name: Chaabouni, Myriam
  last_name: Chaabouni
- first_name: Kshitij
  full_name: Mankad, Kshitij
  last_name: Mankad
- first_name: Evangelia
  full_name: Galanaki, Evangelia
  last_name: Galanaki
- first_name: Stephanie
  full_name: Efthymiou, Stephanie
  last_name: Efthymiou
- first_name: Sniya
  full_name: Sudhakar, Sniya
  last_name: Sudhakar
- first_name: Alkyoni
  full_name: Athanasiou-Fragkouli, Alkyoni
  last_name: Athanasiou-Fragkouli
- first_name: Tamer
  full_name: Celik, Tamer
  last_name: Celik
- first_name: Nejat
  full_name: Narli, Nejat
  last_name: Narli
- first_name: Sebastiano
  full_name: Bianca, Sebastiano
  last_name: Bianca
- first_name: David
  full_name: Murphy, David
  last_name: Murphy
- first_name: Francisco Martins De Carvalho
  full_name: Moreira, Francisco Martins De Carvalho
  last_name: Moreira
- first_name: Andrea
  full_name: Accogli, Andrea
  last_name: Accogli
- first_name: Cassidy
  full_name: Petree, Cassidy
  last_name: Petree
- first_name: Kevin
  full_name: Huang, Kevin
  id: 3b3d2888-1ff6-11ee-9fa6-8f209ca91fe3
  last_name: Huang
  orcid: 0000-0002-2512-7812
- first_name: Kamel
  full_name: Monastiri, Kamel
  last_name: Monastiri
- first_name: Masoud
  full_name: Edizadeh, Masoud
  last_name: Edizadeh
- first_name: Rosaria
  full_name: Nardello, Rosaria
  last_name: Nardello
- first_name: Marzia
  full_name: Ognibene, Marzia
  last_name: Ognibene
- first_name: Patrizia
  full_name: De Marco, Patrizia
  last_name: De Marco
- first_name: Martino
  full_name: Ruggieri, Martino
  last_name: Ruggieri
- first_name: Federico
  full_name: Zara, Federico
  last_name: Zara
- first_name: Pasquale
  full_name: Striano, Pasquale
  last_name: Striano
- first_name: Yavuz
  full_name: Sahin, Yavuz
  last_name: Sahin
- first_name: Lihadh
  full_name: Al-Gazali, Lihadh
  last_name: Al-Gazali
- first_name: Marie Therese Abi
  full_name: Warde, Marie Therese Abi
  last_name: Warde
- first_name: Benedicte
  full_name: Gerard, Benedicte
  last_name: Gerard
- first_name: Giovanni
  full_name: Zifarelli, Giovanni
  last_name: Zifarelli
- first_name: Christian
  full_name: Beetz, Christian
  last_name: Beetz
- first_name: Sara
  full_name: Fortuna, Sara
  last_name: Fortuna
- first_name: Miguel
  full_name: Soler, Miguel
  last_name: Soler
- first_name: Enza Maria
  full_name: Valente, Enza Maria
  last_name: Valente
- first_name: Gaurav
  full_name: Varshney, Gaurav
  last_name: Varshney
- first_name: Reza
  full_name: Maroofian, Reza
  last_name: Maroofian
- first_name: Vincenzo
  full_name: Salpietro, Vincenzo
  last_name: Salpietro
- first_name: Henry
  full_name: Houlden, Henry
  last_name: Houlden
- first_name: SYNaPS Study
  full_name: Grp, SYNaPS Study
  last_name: Grp
citation:
  ama: Cali E, Lin S-J, Rocca C, et al. A homozygous MED11 C-terminal variant causes
    a lethal neurodegenerative disease. <i>Genetics in Medicine</i>. 2022;24(10):2194-2203.
    doi:<a href="https://doi.org/10.1016/j.gim.2022.07.013">10.1016/j.gim.2022.07.013</a>
  apa: Cali, E., Lin, S.-J., Rocca, C., Sahin, Y., Al Shamsi, A., El Chehadeh, S.,
    … Grp, Syn. S. (2022). A homozygous MED11 C-terminal variant causes a lethal neurodegenerative
    disease. <i>Genetics in Medicine</i>. Elsevier. <a href="https://doi.org/10.1016/j.gim.2022.07.013">https://doi.org/10.1016/j.gim.2022.07.013</a>
  chicago: Cali, Elisa, Sheng-Jia Lin, Clarissa Rocca, Yavuz Sahin, Aisha Al Shamsi,
    Salima El Chehadeh, Myriam Chaabouni, et al. “A Homozygous MED11 C-Terminal Variant
    Causes a Lethal Neurodegenerative Disease.” <i>Genetics in Medicine</i>. Elsevier,
    2022. <a href="https://doi.org/10.1016/j.gim.2022.07.013">https://doi.org/10.1016/j.gim.2022.07.013</a>.
  ieee: E. Cali <i>et al.</i>, “A homozygous MED11 C-terminal variant causes a lethal
    neurodegenerative disease,” <i>Genetics in Medicine</i>, vol. 24, no. 10. Elsevier,
    pp. 2194–2203, 2022.
  ista: Cali E, Lin S-J, Rocca C, Sahin Y, Al Shamsi A, El Chehadeh S, Chaabouni M,
    Mankad K, Galanaki E, Efthymiou S, Sudhakar S, Athanasiou-Fragkouli A, Celik T,
    Narli N, Bianca S, Murphy D, Moreira FMDC, Accogli A, Petree C, Huang K, Monastiri
    K, Edizadeh M, Nardello R, Ognibene M, De Marco P, Ruggieri M, Zara F, Striano
    P, Sahin Y, Al-Gazali L, Warde MTA, Gerard B, Zifarelli G, Beetz C, Fortuna S,
    Soler M, Valente EM, Varshney G, Maroofian R, Salpietro V, Houlden H, Grp SynS.
    2022. A homozygous MED11 C-terminal variant causes a lethal neurodegenerative
    disease. Genetics in Medicine. 24(10), 2194–2203.
  mla: Cali, Elisa, et al. “A Homozygous MED11 C-Terminal Variant Causes a Lethal
    Neurodegenerative Disease.” <i>Genetics in Medicine</i>, vol. 24, no. 10, Elsevier,
    2022, pp. 2194–203, doi:<a href="https://doi.org/10.1016/j.gim.2022.07.013">10.1016/j.gim.2022.07.013</a>.
  short: E. Cali, S.-J. Lin, C. Rocca, Y. Sahin, A. Al Shamsi, S. El Chehadeh, M.
    Chaabouni, K. Mankad, E. Galanaki, S. Efthymiou, S. Sudhakar, A. Athanasiou-Fragkouli,
    T. Celik, N. Narli, S. Bianca, D. Murphy, F.M.D.C. Moreira, A. Accogli, C. Petree,
    K. Huang, K. Monastiri, M. Edizadeh, R. Nardello, M. Ognibene, P. De Marco, M.
    Ruggieri, F. Zara, P. Striano, Y. Sahin, L. Al-Gazali, M.T.A. Warde, B. Gerard,
    G. Zifarelli, C. Beetz, S. Fortuna, M. Soler, E.M. Valente, G. Varshney, R. Maroofian,
    V. Salpietro, H. Houlden, Syn.S. Grp, Genetics in Medicine 24 (2022) 2194–2203.
date_created: 2023-09-20T20:57:18Z
date_published: 2022-10-01T00:00:00Z
date_updated: 2023-09-25T08:57:07Z
day: '01'
ddc:
- '570'
department:
- _id: GradSch
doi: 10.1016/j.gim.2022.07.013
extern: '1'
file:
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file_date_updated: 2023-09-25T08:56:06Z
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intvolume: '        24'
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keyword:
- Human mediator complex
- MED11
- MEDopathies
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 2194-2203
publication: Genetics in Medicine
publication_identifier:
  issn:
  - 1098-3600
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: A homozygous MED11 C-terminal variant causes a lethal neurodegenerative disease
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2022'
...
---
_id: '10600'
abstract:
- lang: eng
  text: We show that recent results on adiabatic theory for interacting gapped many-body
    systems on finite lattices remain valid in the thermodynamic limit. More precisely,
    we prove a generalized super-adiabatic theorem for the automorphism group describing
    the infinite volume dynamics on the quasi-local algebra of observables. The key
    assumption is the existence of a sequence of gapped finite volume Hamiltonians,
    which generates the same infinite volume dynamics in the thermodynamic limit.
    Our adiabatic theorem also holds for certain perturbations of gapped ground states
    that close the spectral gap (so it is also an adiabatic theorem for resonances
    and, in this sense, “generalized”), and it provides an adiabatic approximation
    to all orders in the adiabatic parameter (a property often called “super-adiabatic”).
    In addition to the existing results for finite lattices, we also perform a resummation
    of the adiabatic expansion and allow for observables that are not strictly local.
    Finally, as an application, we prove the validity of linear and higher order response
    theory for our class of perturbations for infinite systems. While we consider
    the result and its proof as new and interesting in itself, we also lay the foundation
    for the proof of an adiabatic theorem for systems with a gap only in the bulk,
    which will be presented in a follow-up article.
acknowledgement: J.H. acknowledges partial financial support from ERC Advanced Grant
  “RMTBeyond” No. 101020331.
article_number: '011901'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Sven Joscha
  full_name: Henheik, Sven Joscha
  id: 31d731d7-d235-11ea-ad11-b50331c8d7fb
  last_name: Henheik
  orcid: 0000-0003-1106-327X
- first_name: Stefan
  full_name: Teufel, Stefan
  last_name: Teufel
citation:
  ama: 'Henheik SJ, Teufel S. Adiabatic theorem in the thermodynamic limit: Systems
    with a uniform gap. <i>Journal of Mathematical Physics</i>. 2022;63(1). doi:<a
    href="https://doi.org/10.1063/5.0051632">10.1063/5.0051632</a>'
  apa: 'Henheik, S. J., &#38; Teufel, S. (2022). Adiabatic theorem in the thermodynamic
    limit: Systems with a uniform gap. <i>Journal of Mathematical Physics</i>. AIP
    Publishing. <a href="https://doi.org/10.1063/5.0051632">https://doi.org/10.1063/5.0051632</a>'
  chicago: 'Henheik, Sven Joscha, and Stefan Teufel. “Adiabatic Theorem in the Thermodynamic
    Limit: Systems with a Uniform Gap.” <i>Journal of Mathematical Physics</i>. AIP
    Publishing, 2022. <a href="https://doi.org/10.1063/5.0051632">https://doi.org/10.1063/5.0051632</a>.'
  ieee: 'S. J. Henheik and S. Teufel, “Adiabatic theorem in the thermodynamic limit:
    Systems with a uniform gap,” <i>Journal of Mathematical Physics</i>, vol. 63,
    no. 1. AIP Publishing, 2022.'
  ista: 'Henheik SJ, Teufel S. 2022. Adiabatic theorem in the thermodynamic limit:
    Systems with a uniform gap. Journal of Mathematical Physics. 63(1), 011901.'
  mla: 'Henheik, Sven Joscha, and Stefan Teufel. “Adiabatic Theorem in the Thermodynamic
    Limit: Systems with a Uniform Gap.” <i>Journal of Mathematical Physics</i>, vol.
    63, no. 1, 011901, AIP Publishing, 2022, doi:<a href="https://doi.org/10.1063/5.0051632">10.1063/5.0051632</a>.'
  short: S.J. Henheik, S. Teufel, Journal of Mathematical Physics 63 (2022).
date_created: 2022-01-03T12:19:48Z
date_published: 2022-01-03T00:00:00Z
date_updated: 2023-08-02T13:44:32Z
day: '03'
department:
- _id: GradSch
- _id: LaEr
doi: 10.1063/5.0051632
ec_funded: 1
external_id:
  arxiv:
  - '2012.15238'
  isi:
  - '000739446000009'
intvolume: '        63'
isi: 1
issue: '1'
keyword:
- mathematical physics
- statistical and nonlinear physics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2012.15238
month: '01'
oa: 1
oa_version: Preprint
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
  call_identifier: H2020
  grant_number: '101020331'
  name: Random matrices beyond Wigner-Dyson-Mehta
publication: Journal of Mathematical Physics
publication_identifier:
  eissn:
  - 1089-7658
  issn:
  - 0022-2488
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
status: public
title: 'Adiabatic theorem in the thermodynamic limit: Systems with a uniform gap'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 63
year: '2022'
...
---
_id: '10623'
abstract:
- lang: eng
  text: We investigate the BCS critical temperature Tc in the high-density limit and
    derive an asymptotic formula, which strongly depends on the behavior of the interaction
    potential V on the Fermi-surface. Our results include a rigorous confirmation
    for the behavior of Tc at high densities proposed by Langmann et al. (Phys Rev
    Lett 122:157001, 2019) and identify precise conditions under which superconducting
    domes arise in BCS theory.
acknowledgement: I am very grateful to Robert Seiringer for his guidance during this
  project and for many valuable comments on an earlier version of the manuscript.
  Moreover, I would like to thank Asbjørn Bækgaard Lauritsen for many helpful discussions
  and comments, pointing out the reference [22] and for his involvement in a closely
  related joint project [13]. Finally, I am grateful to Christian Hainzl for valuable
  comments on an earlier version of the manuscript and Andreas Deuchert for interesting
  discussions.
article_number: '3'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Sven Joscha
  full_name: Henheik, Sven Joscha
  id: 31d731d7-d235-11ea-ad11-b50331c8d7fb
  last_name: Henheik
  orcid: 0000-0003-1106-327X
citation:
  ama: Henheik SJ. The BCS critical temperature at high density. <i>Mathematical Physics,
    Analysis and Geometry</i>. 2022;25(1). doi:<a href="https://doi.org/10.1007/s11040-021-09415-0">10.1007/s11040-021-09415-0</a>
  apa: Henheik, S. J. (2022). The BCS critical temperature at high density. <i>Mathematical
    Physics, Analysis and Geometry</i>. Springer Nature. <a href="https://doi.org/10.1007/s11040-021-09415-0">https://doi.org/10.1007/s11040-021-09415-0</a>
  chicago: Henheik, Sven Joscha. “The BCS Critical Temperature at High Density.” <i>Mathematical
    Physics, Analysis and Geometry</i>. Springer Nature, 2022. <a href="https://doi.org/10.1007/s11040-021-09415-0">https://doi.org/10.1007/s11040-021-09415-0</a>.
  ieee: S. J. Henheik, “The BCS critical temperature at high density,” <i>Mathematical
    Physics, Analysis and Geometry</i>, vol. 25, no. 1. Springer Nature, 2022.
  ista: Henheik SJ. 2022. The BCS critical temperature at high density. Mathematical
    Physics, Analysis and Geometry. 25(1), 3.
  mla: Henheik, Sven Joscha. “The BCS Critical Temperature at High Density.” <i>Mathematical
    Physics, Analysis and Geometry</i>, vol. 25, no. 1, 3, Springer Nature, 2022,
    doi:<a href="https://doi.org/10.1007/s11040-021-09415-0">10.1007/s11040-021-09415-0</a>.
  short: S.J. Henheik, Mathematical Physics, Analysis and Geometry 25 (2022).
date_created: 2022-01-13T15:40:53Z
date_published: 2022-01-11T00:00:00Z
date_updated: 2023-08-02T13:51:52Z
day: '11'
ddc:
- '514'
department:
- _id: GradSch
- _id: LaEr
doi: 10.1007/s11040-021-09415-0
ec_funded: 1
external_id:
  arxiv:
  - '2106.02015'
  isi:
  - '000741387600001'
file:
- access_level: open_access
  checksum: d44f8123a52592a75b2c3b8ee2cd2435
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  date_updated: 2022-01-14T07:27:45Z
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  file_size: 505804
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file_date_updated: 2022-01-14T07:27:45Z
has_accepted_license: '1'
intvolume: '        25'
isi: 1
issue: '1'
keyword:
- geometry and topology
- mathematical physics
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
  call_identifier: H2020
  grant_number: '101020331'
  name: Random matrices beyond Wigner-Dyson-Mehta
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
publication: Mathematical Physics, Analysis and Geometry
publication_identifier:
  eissn:
  - 1572-9656
  issn:
  - 1385-0172
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The BCS critical temperature at high density
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 25
year: '2022'
...
---
_id: '10642'
abstract:
- lang: eng
  text: Based on a result by Yarotsky (J Stat Phys 118, 2005), we prove that localized
    but otherwise arbitrary perturbations of weakly interacting quantum spin systems
    with uniformly gapped on-site terms change the ground state of such a system only
    locally, even if they close the spectral gap. We call this a strong version of
    the local perturbations perturb locally (LPPL) principle which is known to hold
    for much more general gapped systems, but only for perturbations that do not close
    the spectral gap of the Hamiltonian. We also extend this strong LPPL-principle
    to Hamiltonians that have the appropriate structure of gapped on-site terms and
    weak interactions only locally in some region of space. While our results are
    technically corollaries to a theorem of Yarotsky, we expect that the paradigm
    of systems with a locally gapped ground state that is completely insensitive to
    the form of the Hamiltonian elsewhere extends to other situations and has important
    physical consequences.
acknowledgement: J. H. acknowledges partial financial support by the ERC Advanced
  Grant “RMTBeyond” No. 101020331. S. T. thanks Marius Lemm and Simone Warzel for
  very helpful comments and discussions and Jürg Fröhlich for references to the literature.
  Open Access funding enabled and organized by Projekt DEAL.
article_number: '9'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Sven Joscha
  full_name: Henheik, Sven Joscha
  id: 31d731d7-d235-11ea-ad11-b50331c8d7fb
  last_name: Henheik
  orcid: 0000-0003-1106-327X
- first_name: Stefan
  full_name: Teufel, Stefan
  last_name: Teufel
- first_name: Tom
  full_name: Wessel, Tom
  last_name: Wessel
citation:
  ama: Henheik SJ, Teufel S, Wessel T. Local stability of ground states in locally
    gapped and weakly interacting quantum spin systems. <i>Letters in Mathematical
    Physics</i>. 2022;112(1). doi:<a href="https://doi.org/10.1007/s11005-021-01494-y">10.1007/s11005-021-01494-y</a>
  apa: Henheik, S. J., Teufel, S., &#38; Wessel, T. (2022). Local stability of ground
    states in locally gapped and weakly interacting quantum spin systems. <i>Letters
    in Mathematical Physics</i>. Springer Nature. <a href="https://doi.org/10.1007/s11005-021-01494-y">https://doi.org/10.1007/s11005-021-01494-y</a>
  chicago: Henheik, Sven Joscha, Stefan Teufel, and Tom Wessel. “Local Stability of
    Ground States in Locally Gapped and Weakly Interacting Quantum Spin Systems.”
    <i>Letters in Mathematical Physics</i>. Springer Nature, 2022. <a href="https://doi.org/10.1007/s11005-021-01494-y">https://doi.org/10.1007/s11005-021-01494-y</a>.
  ieee: S. J. Henheik, S. Teufel, and T. Wessel, “Local stability of ground states
    in locally gapped and weakly interacting quantum spin systems,” <i>Letters in
    Mathematical Physics</i>, vol. 112, no. 1. Springer Nature, 2022.
  ista: Henheik SJ, Teufel S, Wessel T. 2022. Local stability of ground states in
    locally gapped and weakly interacting quantum spin systems. Letters in Mathematical
    Physics. 112(1), 9.
  mla: Henheik, Sven Joscha, et al. “Local Stability of Ground States in Locally Gapped
    and Weakly Interacting Quantum Spin Systems.” <i>Letters in Mathematical Physics</i>,
    vol. 112, no. 1, 9, Springer Nature, 2022, doi:<a href="https://doi.org/10.1007/s11005-021-01494-y">10.1007/s11005-021-01494-y</a>.
  short: S.J. Henheik, S. Teufel, T. Wessel, Letters in Mathematical Physics 112 (2022).
date_created: 2022-01-18T16:18:25Z
date_published: 2022-01-18T00:00:00Z
date_updated: 2023-08-02T13:57:02Z
day: '18'
ddc:
- '530'
department:
- _id: GradSch
- _id: LaEr
doi: 10.1007/s11005-021-01494-y
ec_funded: 1
external_id:
  arxiv:
  - '2106.13780'
  isi:
  - '000744930400001'
file:
- access_level: open_access
  checksum: 7e8e69b76e892c305071a4736131fe18
  content_type: application/pdf
  creator: cchlebak
  date_created: 2022-01-19T09:41:14Z
  date_updated: 2022-01-19T09:41:14Z
  file_id: '10647'
  file_name: 2022_LettersMathPhys_Henheik.pdf
  file_size: 357547
  relation: main_file
  success: 1
file_date_updated: 2022-01-19T09:41:14Z
has_accepted_license: '1'
intvolume: '       112'
isi: 1
issue: '1'
keyword:
- mathematical physics
- statistical and nonlinear physics
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
  call_identifier: H2020
  grant_number: '101020331'
  name: Random matrices beyond Wigner-Dyson-Mehta
publication: Letters in Mathematical Physics
publication_identifier:
  eissn:
  - 1573-0530
  issn:
  - 0377-9017
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Local stability of ground states in locally gapped and weakly interacting quantum
  spin systems
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 112
year: '2022'
...
---
_id: '10643'
abstract:
- lang: eng
  text: "We prove a generalised super-adiabatic theorem for extended fermionic systems
    assuming a spectral gap only in the bulk. More precisely, we assume that the infinite
    system has a unique ground state and that the corresponding Gelfand–Naimark–Segal
    Hamiltonian has a spectral gap above its eigenvalue zero. Moreover, we show that
    a similar adiabatic theorem also holds in the bulk of finite systems up to errors
    that vanish faster than any inverse power of the system size, although the corresponding
    finite-volume Hamiltonians need not have a spectral gap.\r\n\r\n"
acknowledgement: J.H. acknowledges partial financial support by the ERC Advanced Grant
  ‘RMTBeyond’ No. 101020331. Support for publication costs from the Deutsche Forschungsgemeinschaft
  and the Open Access Publishing Fund of the University of Tübingen is gratefully
  acknowledged.
article_number: e4
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Sven Joscha
  full_name: Henheik, Sven Joscha
  id: 31d731d7-d235-11ea-ad11-b50331c8d7fb
  last_name: Henheik
  orcid: 0000-0003-1106-327X
- first_name: Stefan
  full_name: Teufel, Stefan
  last_name: Teufel
citation:
  ama: 'Henheik SJ, Teufel S. Adiabatic theorem in the thermodynamic limit: Systems
    with a gap in the bulk. <i>Forum of Mathematics, Sigma</i>. 2022;10. doi:<a href="https://doi.org/10.1017/fms.2021.80">10.1017/fms.2021.80</a>'
  apa: 'Henheik, S. J., &#38; Teufel, S. (2022). Adiabatic theorem in the thermodynamic
    limit: Systems with a gap in the bulk. <i>Forum of Mathematics, Sigma</i>. Cambridge
    University Press. <a href="https://doi.org/10.1017/fms.2021.80">https://doi.org/10.1017/fms.2021.80</a>'
  chicago: 'Henheik, Sven Joscha, and Stefan Teufel. “Adiabatic Theorem in the Thermodynamic
    Limit: Systems with a Gap in the Bulk.” <i>Forum of Mathematics, Sigma</i>. Cambridge
    University Press, 2022. <a href="https://doi.org/10.1017/fms.2021.80">https://doi.org/10.1017/fms.2021.80</a>.'
  ieee: 'S. J. Henheik and S. Teufel, “Adiabatic theorem in the thermodynamic limit:
    Systems with a gap in the bulk,” <i>Forum of Mathematics, Sigma</i>, vol. 10.
    Cambridge University Press, 2022.'
  ista: 'Henheik SJ, Teufel S. 2022. Adiabatic theorem in the thermodynamic limit:
    Systems with a gap in the bulk. Forum of Mathematics, Sigma. 10, e4.'
  mla: 'Henheik, Sven Joscha, and Stefan Teufel. “Adiabatic Theorem in the Thermodynamic
    Limit: Systems with a Gap in the Bulk.” <i>Forum of Mathematics, Sigma</i>, vol.
    10, e4, Cambridge University Press, 2022, doi:<a href="https://doi.org/10.1017/fms.2021.80">10.1017/fms.2021.80</a>.'
  short: S.J. Henheik, S. Teufel, Forum of Mathematics, Sigma 10 (2022).
date_created: 2022-01-18T16:18:51Z
date_published: 2022-01-18T00:00:00Z
date_updated: 2023-08-02T13:53:11Z
day: '18'
ddc:
- '510'
department:
- _id: GradSch
- _id: LaEr
doi: 10.1017/fms.2021.80
ec_funded: 1
external_id:
  arxiv:
  - '2012.15239'
  isi:
  - '000743615000001'
file:
- access_level: open_access
  checksum: 87592a755adcef22ea590a99dc728dd3
  content_type: application/pdf
  creator: cchlebak
  date_created: 2022-01-19T09:27:43Z
  date_updated: 2022-01-19T09:27:43Z
  file_id: '10646'
  file_name: 2022_ForumMathSigma_Henheik.pdf
  file_size: 705323
  relation: main_file
  success: 1
file_date_updated: 2022-01-19T09:27:43Z
has_accepted_license: '1'
intvolume: '        10'
isi: 1
keyword:
- computational mathematics
- discrete mathematics and combinatorics
- geometry and topology
- mathematical physics
- statistics and probability
- algebra and number theory
- theoretical computer science
- analysis
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
  call_identifier: H2020
  grant_number: '101020331'
  name: Random matrices beyond Wigner-Dyson-Mehta
publication: Forum of Mathematics, Sigma
publication_identifier:
  eissn:
  - 2050-5094
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
status: public
title: 'Adiabatic theorem in the thermodynamic limit: Systems with a gap in the bulk'
tmp:
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  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 10
year: '2022'
...
---
_id: '10658'
abstract:
- lang: eng
  text: We analyse how migration from a large mainland influences genetic load and
    population numbers on an island, in a scenario where fitness-affecting variants
    are unconditionally deleterious, and where numbers decline with increasing load.
    Our analysis shows that migration can have qualitatively different effects, depending
    on the total mutation target and fitness effects of deleterious variants. In particular,
    we find that populations exhibit a genetic Allee effect across a wide range of
    parameter combinations, when variants are partially recessive, cycling between
    low-load (large-population) and high-load (sink) states. Increased migration reduces
    load in the sink state (by increasing heterozygosity) but further inflates load
    in the large-population state (by hindering purging). We identify various critical
    parameter thresholds at which one or other stable state collapses, and discuss
    how these thresholds are influenced by the genetic versus demographic effects
    of migration. Our analysis is based on a ‘semi-deterministic’ analysis, which
    accounts for genetic drift but neglects demographic stochasticity. We also compare
    against simulations which account for both demographic stochasticity and drift.
    Our results clarify the importance of gene flow as a key determinant of extinction
    risk in peripheral populations, even in the absence of ecological gradients. This
    article is part of the theme issue ‘Species’ ranges in the face of changing environments
    (part I)’.
acknowledgement: This research was partly funded by the Austrian Science Fund (FWF)
  (grant no. P-32896B).
article_number: '20210010'
article_processing_charge: No
article_type: original
author:
- first_name: Himani
  full_name: Sachdeva, Himani
  last_name: Sachdeva
- first_name: Oluwafunmilola O
  full_name: Olusanya, Oluwafunmilola O
  id: 41AD96DC-F248-11E8-B48F-1D18A9856A87
  last_name: Olusanya
  orcid: 0000-0003-1971-8314
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: 'Sachdeva H, Olusanya OO, Barton NH. Genetic load and extinction in peripheral
    populations: The roles of migration, drift and demographic stochasticity. <i>Philosophical
    Transactions of the Royal Society B</i>. 2022;377(1846). doi:<a href="https://doi.org/10.1098/rstb.2021.0010">10.1098/rstb.2021.0010</a>'
  apa: 'Sachdeva, H., Olusanya, O. O., &#38; Barton, N. H. (2022). Genetic load and
    extinction in peripheral populations: The roles of migration, drift and demographic
    stochasticity. <i>Philosophical Transactions of the Royal Society B</i>. The Royal
    Society. <a href="https://doi.org/10.1098/rstb.2021.0010">https://doi.org/10.1098/rstb.2021.0010</a>'
  chicago: 'Sachdeva, Himani, Oluwafunmilola O Olusanya, and Nicholas H Barton. “Genetic
    Load and Extinction in Peripheral Populations: The Roles of Migration, Drift and
    Demographic Stochasticity.” <i>Philosophical Transactions of the Royal Society
    B</i>. The Royal Society, 2022. <a href="https://doi.org/10.1098/rstb.2021.0010">https://doi.org/10.1098/rstb.2021.0010</a>.'
  ieee: 'H. Sachdeva, O. O. Olusanya, and N. H. Barton, “Genetic load and extinction
    in peripheral populations: The roles of migration, drift and demographic stochasticity,”
    <i>Philosophical Transactions of the Royal Society B</i>, vol. 377, no. 1846.
    The Royal Society, 2022.'
  ista: 'Sachdeva H, Olusanya OO, Barton NH. 2022. Genetic load and extinction in
    peripheral populations: The roles of migration, drift and demographic stochasticity.
    Philosophical Transactions of the Royal Society B. 377(1846), 20210010.'
  mla: 'Sachdeva, Himani, et al. “Genetic Load and Extinction in Peripheral Populations:
    The Roles of Migration, Drift and Demographic Stochasticity.” <i>Philosophical
    Transactions of the Royal Society B</i>, vol. 377, no. 1846, 20210010, The Royal
    Society, 2022, doi:<a href="https://doi.org/10.1098/rstb.2021.0010">10.1098/rstb.2021.0010</a>.'
  short: H. Sachdeva, O.O. Olusanya, N.H. Barton, Philosophical Transactions of the
    Royal Society B 377 (2022).
date_created: 2022-01-24T10:34:53Z
date_published: 2022-01-24T00:00:00Z
date_updated: 2025-05-26T09:05:09Z
day: '24'
ddc:
- '576'
department:
- _id: GradSch
- _id: NiBa
doi: 10.1098/rstb.2021.0010
external_id:
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  - '000745854300008'
  pmid:
  - '35067097'
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intvolume: '       377'
isi: 1
issue: '1846'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: c08d3278-5a5b-11eb-8a69-fdb09b55f4b8
  grant_number: P32896
  name: Causes and consequences of population fragmentation
publication: Philosophical Transactions of the Royal Society B
publication_identifier:
  eissn:
  - 1471-2970
  issn:
  - 0962-8436
publication_status: published
publisher: The Royal Society
quality_controlled: '1'
related_material:
  link:
  - relation: earlier_version
    url: https://doi.org/10.1101/2021.08.05.455207
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  - id: '14711'
    relation: dissertation_contains
    status: public
status: public
title: 'Genetic load and extinction in peripheral populations: The roles of migration,
  drift and demographic stochasticity'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 377
year: '2022'
...
---
_id: '10727'
abstract:
- lang: eng
  text: "Social insects are a common model to study disease dynamics in social animals.
    Even though pathogens should thrive in social insect colonies as the hosts engage
    in frequent social interactions, are closely related and live in a pathogen-rich
    environment, disease outbreaks are rare. This is because social insects have evolved
    mechanisms to keep pathogens at bay – and fight disease as a collective. Social
    insect colonies are often viewed as “superorganisms” with division of labor between
    reproductive “germ-like” queens and males and “somatic” workers, which together
    form an interdependent reproductive unit that parallels a multicellular body.
    Superorganisms possess a “social immune system” that comprises of collective disease
    defenses performed by the workers - summarized as “social immunity”. In social
    groups immunization (reduced susceptibility to a parasite upon secondary exposure
    to the same parasite) can e.g. be triggered by social interactions (“social immunization”).
    Social immunization can be caused by (i) asymptomatic low-level infections that
    are acquired during caregiving to a contagious individual that can give an immune
    boost, which can induce protection upon later encounter with the same pathogen
    (active immunization) or (ii) by transfer of immune effectors between individuals
    (passive immunization).\r\nIn the second chapter, I built up on a study that I
    co-authored that found that low-level infections can not only be protective, but
    also be costly and make the host more susceptible to detrimental superinfections
    after contact to a very dissimilar pathogen. I here now tested different degrees
    of phylogenetically-distant fungal strains of M. brunneum and M. robertsii in
    L. neglectus and can describe the occurrence of cross-protection of social immunization
    if the first and second pathogen are from the same level. Interestingly, low-level
    infections only provided protection when the first strain was less virulent than
    the second strain and elicited higher immune gene expression.\r\nIn the third
    and fourth chapters, I expanded on the role of social immunity in sexual selection,
    a so far unstudied field. I used the fungus Metarhizium robertsii and the ant
    Cardiocondyla obscurior as a model, as in this species mating occurs in the presence
    of workers and can be studied under laboratory conditions. Before males mate with
    virgin queens in the nest they engage in fierce combat over the access to their
    mating partners.\r\nFirst, I focused on male-male competition in the third chapter
    and found that fighting with a contagious male is costly as it can lead to contamination
    of the rival, but that workers can decrease the risk of disease contraction by
    performing sanitary care.\r\nIn the fourth chapter, I studied the effect of fungal
    infection on survival and mating success of sexuals (freshly emerged queens and
    males) and found that worker-performed sanitary care can buffer the negative effect
    that a pathogenic contagion would have on sexuals by spore removal from the exposed
    individuals. When social immunity was prevented and queens could contract spores
    from their mating partner, very low dosages led to negative consequences: their
    lifespan was reduced and they produced fewer offspring with poor immunocompetence
    compared to healthy queens. Interestingly, cohabitation with a late-stage infected
    male where no spore transfer was possible had a positive effect on offspring immunity
    – male offspring of mothers that apparently perceived an infected partner in their
    vicinity reacted more sensitively to fungal challenge than male offspring without
    paternal pathogen history."
acknowledged_ssus:
- _id: LifeSc
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Sina
  full_name: Metzler, Sina
  id: 48204546-F248-11E8-B48F-1D18A9856A87
  last_name: Metzler
  orcid: 0000-0002-9547-2494
citation:
  ama: Metzler S. Pathogen-mediated sexual selection and immunization in ant colonies.
    2022. doi:<a href="https://doi.org/10.15479/AT:ISTA:10727">10.15479/AT:ISTA:10727</a>
  apa: Metzler, S. (2022). <i>Pathogen-mediated sexual selection and immunization
    in ant colonies</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:10727">https://doi.org/10.15479/AT:ISTA:10727</a>
  chicago: Metzler, Sina. “Pathogen-Mediated Sexual Selection and Immunization in
    Ant Colonies.” Institute of Science and Technology Austria, 2022. <a href="https://doi.org/10.15479/AT:ISTA:10727">https://doi.org/10.15479/AT:ISTA:10727</a>.
  ieee: S. Metzler, “Pathogen-mediated sexual selection and immunization in ant colonies,”
    Institute of Science and Technology Austria, 2022.
  ista: Metzler S. 2022. Pathogen-mediated sexual selection and immunization in ant
    colonies. Institute of Science and Technology Austria.
  mla: Metzler, Sina. <i>Pathogen-Mediated Sexual Selection and Immunization in Ant
    Colonies</i>. Institute of Science and Technology Austria, 2022, doi:<a href="https://doi.org/10.15479/AT:ISTA:10727">10.15479/AT:ISTA:10727</a>.
  short: S. Metzler, Pathogen-Mediated Sexual Selection and Immunization in Ant Colonies,
    Institute of Science and Technology Austria, 2022.
date_created: 2022-02-04T15:45:12Z
date_published: 2022-02-07T00:00:00Z
date_updated: 2023-09-07T13:43:23Z
day: '07'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: SyCr
doi: 10.15479/AT:ISTA:10727
ec_funded: 1
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file_date_updated: 2023-02-04T23:30:03Z
has_accepted_license: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 2649B4DE-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '771402'
  name: Epidemics in ant societies on a chip
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
title: Pathogen-mediated sexual selection and immunization in ant colonies
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2022'
...
---
_id: '10759'
abstract:
- lang: eng
  text: In this Thesis, I study composite quantum impurities with variational techniques,
    both inspired by machine learning as well as fully analytic. I supplement this
    with exploration of other applications of machine learning, in particular artificial
    neural networks, in many-body physics. In Chapters 3 and 4, I study quasiparticle
    systems with variational approach. I derive a Hamiltonian describing the angulon
    quasiparticle in the presence of a magnetic field. I apply analytic variational
    treatment to this Hamiltonian. Then, I introduce a variational approach for non-additive
    systems, based on artificial neural networks. I exemplify this approach on the
    example of the polaron quasiparticle (Fröhlich Hamiltonian). In Chapter 5, I continue
    using artificial neural networks, albeit in a different setting. I apply artificial
    neural networks to detect phases from snapshots of two types physical systems.
    Namely, I study Monte Carlo snapshots of multilayer classical spin models as well
    as molecular dynamics maps of colloidal systems. The main type of networks that
    I use here are convolutional neural networks, known for their applicability to
    image data.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Wojciech
  full_name: Rzadkowski, Wojciech
  id: 48C55298-F248-11E8-B48F-1D18A9856A87
  last_name: Rzadkowski
  orcid: 0000-0002-1106-4419
citation:
  ama: Rzadkowski W. Analytic and machine learning approaches to composite quantum
    impurities. 2022. doi:<a href="https://doi.org/10.15479/at:ista:10759">10.15479/at:ista:10759</a>
  apa: Rzadkowski, W. (2022). <i>Analytic and machine learning approaches to composite
    quantum impurities</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:10759">https://doi.org/10.15479/at:ista:10759</a>
  chicago: Rzadkowski, Wojciech. “Analytic and Machine Learning Approaches to Composite
    Quantum Impurities.” Institute of Science and Technology Austria, 2022. <a href="https://doi.org/10.15479/at:ista:10759">https://doi.org/10.15479/at:ista:10759</a>.
  ieee: W. Rzadkowski, “Analytic and machine learning approaches to composite quantum
    impurities,” Institute of Science and Technology Austria, 2022.
  ista: Rzadkowski W. 2022. Analytic and machine learning approaches to composite
    quantum impurities. Institute of Science and Technology Austria.
  mla: Rzadkowski, Wojciech. <i>Analytic and Machine Learning Approaches to Composite
    Quantum Impurities</i>. Institute of Science and Technology Austria, 2022, doi:<a
    href="https://doi.org/10.15479/at:ista:10759">10.15479/at:ista:10759</a>.
  short: W. Rzadkowski, Analytic and Machine Learning Approaches to Composite Quantum
    Impurities, Institute of Science and Technology Austria, 2022.
date_created: 2022-02-16T13:27:37Z
date_published: 2022-02-21T00:00:00Z
date_updated: 2024-08-07T07:16:53Z
day: '21'
ddc:
- '530'
degree_awarded: PhD
department:
- _id: GradSch
- _id: MiLe
doi: 10.15479/at:ista:10759
ec_funded: 1
file:
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  checksum: 0fc54ad1eaede879c665ac9b53c93e22
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  date_created: 2022-02-21T13:58:16Z
  date_updated: 2022-02-22T07:20:12Z
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  success: 1
file_date_updated: 2022-02-22T07:20:12Z
has_accepted_license: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: '120'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    status: public
  - id: '7956'
    relation: part_of_dissertation
    status: public
  - id: '415'
    relation: part_of_dissertation
    status: public
  - id: '8644'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Mikhail
  full_name: Lemeshko, Mikhail
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
title: Analytic and machine learning approaches to composite quantum impurities
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2022'
...
---
_id: '10787'
abstract:
- lang: eng
  text: "A species distributed across diverse environments may adapt to local conditions.
    We ask how quickly such a species changes its range in response to changed conditions.
    Szép et al. (Szép E, Sachdeva H, Barton NH. 2021 Polygenic local adaptation in
    metapopulations: a stochastic eco-evolutionary model. Evolution75, 1030–1045 (doi:10.1111/evo.14210))
    used the infinite island model to find the stationary distribution of allele frequencies
    and deme sizes. We extend this to find how a metapopulation responds to changes
    in carrying capacity, selection strength, or migration rate when deme sizes are
    fixed. We further develop a ‘fixed-state’ approximation. Under this approximation,
    polymorphism is only possible for a narrow range of habitat proportions when selection
    is weak compared to drift, but for a much wider range otherwise. When rates of
    selection or migration relative to drift change in a single deme of the metapopulation,
    the population takes a time of order m−1 to reach the new equilibrium. However,
    even with many loci, there can be substantial fluctuations in net adaptation,
    because at each locus, alleles randomly get lost or fixed. Thus, in a finite metapopulation,
    variation may gradually be lost by chance, even if it would persist in an infinite
    metapopulation. When conditions change across the whole metapopulation, there
    can be rapid change, which is predicted well by the fixed-state approximation.
    This work helps towards an understanding of how metapopulations extend their range
    across diverse environments.\r\nThis article is part of the theme issue ‘Species’
    ranges in the face of changing environments (Part II)’."
acknowledgement: This research was partly funded by the Austrian Science Fund (FWF)
  [FWF P-32896B].
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Oluwafunmilola O
  full_name: Olusanya, Oluwafunmilola O
  id: 41AD96DC-F248-11E8-B48F-1D18A9856A87
  last_name: Olusanya
  orcid: 0000-0003-1971-8314
citation:
  ama: 'Barton NH, Olusanya OO. The response of a metapopulation to a changing environment.
    <i>Philosophical Transactions of the Royal Society B: Biological Sciences</i>.
    2022;377(1848). doi:<a href="https://doi.org/10.1098/rstb.2021.0009">10.1098/rstb.2021.0009</a>'
  apa: 'Barton, N. H., &#38; Olusanya, O. O. (2022). The response of a metapopulation
    to a changing environment. <i>Philosophical Transactions of the Royal Society
    B: Biological Sciences</i>. The Royal Society. <a href="https://doi.org/10.1098/rstb.2021.0009">https://doi.org/10.1098/rstb.2021.0009</a>'
  chicago: 'Barton, Nicholas H, and Oluwafunmilola O Olusanya. “The Response of a
    Metapopulation to a Changing Environment.” <i>Philosophical Transactions of the
    Royal Society B: Biological Sciences</i>. The Royal Society, 2022. <a href="https://doi.org/10.1098/rstb.2021.0009">https://doi.org/10.1098/rstb.2021.0009</a>.'
  ieee: 'N. H. Barton and O. O. Olusanya, “The response of a metapopulation to a changing
    environment,” <i>Philosophical Transactions of the Royal Society B: Biological
    Sciences</i>, vol. 377, no. 1848. The Royal Society, 2022.'
  ista: 'Barton NH, Olusanya OO. 2022. The response of a metapopulation to a changing
    environment. Philosophical Transactions of the Royal Society B: Biological Sciences.
    377(1848).'
  mla: 'Barton, Nicholas H., and Oluwafunmilola O. Olusanya. “The Response of a Metapopulation
    to a Changing Environment.” <i>Philosophical Transactions of the Royal Society
    B: Biological Sciences</i>, vol. 377, no. 1848, The Royal Society, 2022, doi:<a
    href="https://doi.org/10.1098/rstb.2021.0009">10.1098/rstb.2021.0009</a>.'
  short: 'N.H. Barton, O.O. Olusanya, Philosophical Transactions of the Royal Society
    B: Biological Sciences 377 (2022).'
date_created: 2022-02-21T16:08:10Z
date_published: 2022-04-11T00:00:00Z
date_updated: 2025-05-26T09:05:09Z
day: '11'
ddc:
- '570'
department:
- _id: GradSch
- _id: NiBa
doi: 10.1098/rstb.2021.0009
external_id:
  isi:
  - '000758140300001'
  pmid:
  - '35184588'
file:
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intvolume: '       377'
isi: 1
issue: '1848'
keyword:
- General Agricultural and Biological Sciences
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: c08d3278-5a5b-11eb-8a69-fdb09b55f4b8
  grant_number: P32896
  name: Causes and consequences of population fragmentation
publication: 'Philosophical Transactions of the Royal Society B: Biological Sciences'
publication_identifier:
  eissn:
  - 1471-2970
  issn:
  - 0962-8436
publication_status: published
publisher: The Royal Society
quality_controlled: '1'
related_material:
  record:
  - id: '14711'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: The response of a metapopulation to a changing environment
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 377
year: '2022'
...
---
_id: '10799'
abstract:
- lang: eng
  text: "Because of the increasing popularity of machine learning methods, it is becoming
    important to understand the impact of learned components on automated decision-making
    systems and to guarantee that their consequences are beneficial to society. In
    other words, it is necessary to ensure that machine learning is sufficiently trustworthy
    to be used in real-world applications. This thesis studies two properties of machine
    learning models that are highly desirable for the\r\nsake of reliability: robustness
    and fairness. In the first part of the thesis we study the robustness of learning
    algorithms to training data corruption. Previous work has shown that machine learning
    models are vulnerable to a range\r\nof training set issues, varying from label
    noise through systematic biases to worst-case data manipulations. This is an especially
    relevant problem from a present perspective, since modern machine learning methods
    are particularly data hungry and therefore practitioners often have to rely on
    data collected from various external sources, e.g. from the Internet, from app
    users or via crowdsourcing. Naturally, such sources vary greatly in the quality
    and reliability of the\r\ndata they provide. With these considerations in mind,
    we study the problem of designing machine learning algorithms that are robust
    to corruptions in data coming from multiple sources. We show that, in contrast
    to the case of a single dataset with outliers, successful learning within this
    model is possible both theoretically and practically, even under worst-case data
    corruptions. The second part of this thesis deals with fairness-aware machine
    learning. There are multiple areas where machine learning models have shown promising
    results, but where careful considerations are required, in order to avoid discrimanative
    decisions taken by such learned components. Ensuring fairness can be particularly
    challenging, because real-world training datasets are expected to contain various
    forms of historical bias that may affect the learning process. In this thesis
    we show that data corruption can indeed render the problem of achieving fairness
    impossible, by tightly characterizing the theoretical limits of fair learning
    under worst-case data manipulations. However, assuming access to clean data, we
    also show how fairness-aware learning can be made practical in contexts beyond
    binary classification, in particular in the challenging learning to rank setting."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Nikola H
  full_name: Konstantinov, Nikola H
  id: 4B9D76E4-F248-11E8-B48F-1D18A9856A87
  last_name: Konstantinov
citation:
  ama: Konstantinov NH. Robustness and fairness in machine learning. 2022. doi:<a
    href="https://doi.org/10.15479/at:ista:10799">10.15479/at:ista:10799</a>
  apa: Konstantinov, N. H. (2022). <i>Robustness and fairness in machine learning</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:10799">https://doi.org/10.15479/at:ista:10799</a>
  chicago: Konstantinov, Nikola H. “Robustness and Fairness in Machine Learning.”
    Institute of Science and Technology Austria, 2022. <a href="https://doi.org/10.15479/at:ista:10799">https://doi.org/10.15479/at:ista:10799</a>.
  ieee: N. H. Konstantinov, “Robustness and fairness in machine learning,” Institute
    of Science and Technology Austria, 2022.
  ista: Konstantinov NH. 2022. Robustness and fairness in machine learning. Institute
    of Science and Technology Austria.
  mla: Konstantinov, Nikola H. <i>Robustness and Fairness in Machine Learning</i>.
    Institute of Science and Technology Austria, 2022, doi:<a href="https://doi.org/10.15479/at:ista:10799">10.15479/at:ista:10799</a>.
  short: N.H. Konstantinov, Robustness and Fairness in Machine Learning, Institute
    of Science and Technology Austria, 2022.
date_created: 2022-02-28T13:03:49Z
date_published: 2022-03-08T00:00:00Z
date_updated: 2023-10-17T12:31:54Z
day: '08'
ddc:
- '000'
degree_awarded: PhD
department:
- _id: GradSch
- _id: ChLa
doi: 10.15479/at:ista:10799
ec_funded: 1
file:
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  file_size: 22841103
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file_date_updated: 2022-03-10T12:11:48Z
has_accepted_license: '1'
keyword:
- robustness
- fairness
- machine learning
- PAC learning
- adversarial learning
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: '176'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication_identifier:
  isbn:
  - 978-3-99078-015-2
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    status: public
  - id: '10802'
    relation: part_of_dissertation
    status: public
  - id: '6590'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
title: Robustness and fairness in machine learning
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2022'
...
---
_id: '10842'
abstract:
- lang: eng
  text: We determine the unique factorization of some polynomials over a finite local
    commutative ring with identity explicitly. This solves and generalizes the main
    conjecture of Qian, Shi and Solé in [13]. We also give some applications to enumeration
    of certain generalized double circulant self-dual and linear complementary dual
    (LCD) codes over some finite rings together with an application in asymptotic
    coding theory.
acknowledgement: The authors would like to thank Prof. Dr. Minjia Shi for bringing
  [13, Conjecture 3.5] to our attention. We would also like to thank the associate
  editor and anonymous reviewers for their valuable comments and suggestions which
  improved and clarified the manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Seyda
  full_name: Köse, Seyda
  id: 8ba3170d-dc85-11ea-9058-c4251c96a6eb
  last_name: Köse
- first_name: Ferruh
  full_name: Özbudak, Ferruh
  last_name: Özbudak
citation:
  ama: Köse S, Özbudak F. Factorization of some polynomials over finite local commutative
    rings and applications to certain self-dual and LCD codes. <i>Cryptography and
    Communications</i>. 2022;14(4):933-948. doi:<a href="https://doi.org/10.1007/s12095-022-00557-8">10.1007/s12095-022-00557-8</a>
  apa: Köse, S., &#38; Özbudak, F. (2022). Factorization of some polynomials over
    finite local commutative rings and applications to certain self-dual and LCD codes.
    <i>Cryptography and Communications</i>. Springer Nature. <a href="https://doi.org/10.1007/s12095-022-00557-8">https://doi.org/10.1007/s12095-022-00557-8</a>
  chicago: Köse, Seyda, and Ferruh Özbudak. “Factorization of Some Polynomials over
    Finite Local Commutative Rings and Applications to Certain Self-Dual and LCD Codes.”
    <i>Cryptography and Communications</i>. Springer Nature, 2022. <a href="https://doi.org/10.1007/s12095-022-00557-8">https://doi.org/10.1007/s12095-022-00557-8</a>.
  ieee: S. Köse and F. Özbudak, “Factorization of some polynomials over finite local
    commutative rings and applications to certain self-dual and LCD codes,” <i>Cryptography
    and Communications</i>, vol. 14, no. 4. Springer Nature, pp. 933–948, 2022.
  ista: Köse S, Özbudak F. 2022. Factorization of some polynomials over finite local
    commutative rings and applications to certain self-dual and LCD codes. Cryptography
    and Communications. 14(4), 933–948.
  mla: Köse, Seyda, and Ferruh Özbudak. “Factorization of Some Polynomials over Finite
    Local Commutative Rings and Applications to Certain Self-Dual and LCD Codes.”
    <i>Cryptography and Communications</i>, vol. 14, no. 4, Springer Nature, 2022,
    pp. 933–48, doi:<a href="https://doi.org/10.1007/s12095-022-00557-8">10.1007/s12095-022-00557-8</a>.
  short: S. Köse, F. Özbudak, Cryptography and Communications 14 (2022) 933–948.
date_created: 2022-03-10T12:16:19Z
date_published: 2022-07-01T00:00:00Z
date_updated: 2023-09-05T15:35:55Z
day: '01'
department:
- _id: GradSch
doi: 10.1007/s12095-022-00557-8
external_id:
  isi:
  - '000766422000002'
intvolume: '        14'
isi: 1
issue: '4'
keyword:
- Applied Mathematics
- Computational Theory and Mathematics
- Computer Networks and Communications
language:
- iso: eng
month: '07'
oa_version: None
page: 933-948
publication: Cryptography and Communications
publication_identifier:
  eissn:
  - 1936-2455
  issn:
  - 1936-2447
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Factorization of some polynomials over finite local commutative rings and applications
  to certain self-dual and LCD codes
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 14
year: '2022'
...
---
_id: '10850'
abstract:
- lang: eng
  text: "We study two interacting quantum particles forming a bound state in d-dimensional
    free\r\nspace, and constrain the particles in k directions to (0, ∞)k ×Rd−k, with
    Neumann boundary\r\nconditions. First, we prove that the ground state energy strictly
    decreases upon going from k\r\nto k+1. This shows that the particles stick to
    the corner where all boundary planes intersect.\r\nSecond, we show that for all
    k the resulting Hamiltonian, after removing the free part of the\r\nkinetic energy,
    has only finitely many eigenvalues below the essential spectrum. This paper\r\ngeneralizes
    the work of Egger, Kerner and Pankrashkin (J. Spectr. Theory 10(4):1413–1444,\r\n2020)
    to dimensions d > 1."
acknowledgement: We thank Rupert Frank for contributing Appendix B. Funding from the
  European Union's Horizon 2020 research and innovation programme under the ERC grant
  agreement No. 694227 is gratefully acknowledged.
article_number: '109455'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Barbara
  full_name: Roos, Barbara
  id: 5DA90512-D80F-11E9-8994-2E2EE6697425
  last_name: Roos
  orcid: 0000-0002-9071-5880
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
citation:
  ama: Roos B, Seiringer R. Two-particle bound states at interfaces and corners. <i>Journal
    of Functional Analysis</i>. 2022;282(12). doi:<a href="https://doi.org/10.1016/j.jfa.2022.109455">10.1016/j.jfa.2022.109455</a>
  apa: Roos, B., &#38; Seiringer, R. (2022). Two-particle bound states at interfaces
    and corners. <i>Journal of Functional Analysis</i>. Elsevier. <a href="https://doi.org/10.1016/j.jfa.2022.109455">https://doi.org/10.1016/j.jfa.2022.109455</a>
  chicago: Roos, Barbara, and Robert Seiringer. “Two-Particle Bound States at Interfaces
    and Corners.” <i>Journal of Functional Analysis</i>. Elsevier, 2022. <a href="https://doi.org/10.1016/j.jfa.2022.109455">https://doi.org/10.1016/j.jfa.2022.109455</a>.
  ieee: B. Roos and R. Seiringer, “Two-particle bound states at interfaces and corners,”
    <i>Journal of Functional Analysis</i>, vol. 282, no. 12. Elsevier, 2022.
  ista: Roos B, Seiringer R. 2022. Two-particle bound states at interfaces and corners.
    Journal of Functional Analysis. 282(12), 109455.
  mla: Roos, Barbara, and Robert Seiringer. “Two-Particle Bound States at Interfaces
    and Corners.” <i>Journal of Functional Analysis</i>, vol. 282, no. 12, 109455,
    Elsevier, 2022, doi:<a href="https://doi.org/10.1016/j.jfa.2022.109455">10.1016/j.jfa.2022.109455</a>.
  short: B. Roos, R. Seiringer, Journal of Functional Analysis 282 (2022).
date_created: 2022-03-16T08:41:53Z
date_published: 2022-06-15T00:00:00Z
date_updated: 2023-10-27T10:37:29Z
day: '15'
ddc:
- '510'
department:
- _id: GradSch
- _id: RoSe
doi: 10.1016/j.jfa.2022.109455
ec_funded: 1
external_id:
  arxiv:
  - '2105.04874'
  isi:
  - '000795160200009'
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  success: 1
file_date_updated: 2022-08-02T10:37:55Z
has_accepted_license: '1'
intvolume: '       282'
isi: 1
issue: '12'
keyword:
- Analysis
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694227'
  name: Analysis of quantum many-body systems
publication: Journal of Functional Analysis
publication_identifier:
  issn:
  - 0022-1236
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
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    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Two-particle bound states at interfaces and corners
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 282
year: '2022'
...
