---
_id: '15037'
abstract:
- lang: eng
  text: Protein abundance and localization at the plasma membrane (PM) shapes plant
    development and mediates adaptation to changing environmental conditions. It is
    regulated by ubiquitination, a post-translational modification crucial for the
    proper sorting of endocytosed PM proteins to the vacuole for subsequent degradation.
    To understand the significance and the variety of roles played by this reversible
    modification, the function of ubiquitin receptors, which translate the ubiquitin
    signature into a cellular response, needs to be elucidated. In this study, we
    show that TOL (TOM1-like) proteins function in plants as multivalent ubiquitin
    receptors, governing ubiquitinated cargo delivery to the vacuole via the conserved
    Endosomal Sorting Complex Required for Transport (ESCRT) pathway. TOL2 and TOL6
    interact with components of the ESCRT machinery and bind to K63-linked ubiquitin
    via two tandemly arranged conserved ubiquitin-binding domains. Mutation of these
    domains results not only in a loss of ubiquitin binding but also altered localization,
    abolishing TOL6 ubiquitin receptor activity. Function and localization of TOL6
    is itself regulated by ubiquitination, whereby TOL6 ubiquitination potentially
    modulates degradation of PM-localized cargoes, assisting in the fine-tuning of
    the delicate interplay between protein recycling and downregulation. Taken together,
    our findings demonstrate the function and regulation of a ubiquitin receptor that
    mediates vacuolar degradation of PM proteins in higher plants.
article_processing_charge: No
article_type: original
author:
- first_name: Jeanette
  full_name: Moulinier-Anzola, Jeanette
  last_name: Moulinier-Anzola
- first_name: Maximilian
  full_name: Schwihla, Maximilian
  last_name: Schwihla
- first_name: Lucinda
  full_name: De-Araújo, Lucinda
  last_name: De-Araújo
- first_name: Christina
  full_name: Artner, Christina
  id: 45DF286A-F248-11E8-B48F-1D18A9856A87
  last_name: Artner
- first_name: Lisa
  full_name: Jörg, Lisa
  last_name: Jörg
- first_name: Nataliia
  full_name: Konstantinova, Nataliia
  last_name: Konstantinova
- first_name: Christian
  full_name: Luschnig, Christian
  last_name: Luschnig
- first_name: Barbara
  full_name: Korbei, Barbara
  last_name: Korbei
citation:
  ama: Moulinier-Anzola J, Schwihla M, De-Araújo L, et al. TOLs function as ubiquitin
    receptors in the early steps of the ESCRT pathway in higher plants. <i>Molecular
    Plant</i>. 2020;13(5):717-731. doi:<a href="https://doi.org/10.1016/j.molp.2020.02.012">10.1016/j.molp.2020.02.012</a>
  apa: Moulinier-Anzola, J., Schwihla, M., De-Araújo, L., Artner, C., Jörg, L., Konstantinova,
    N., … Korbei, B. (2020). TOLs function as ubiquitin receptors in the early steps
    of the ESCRT pathway in higher plants. <i>Molecular Plant</i>. Elsevier. <a href="https://doi.org/10.1016/j.molp.2020.02.012">https://doi.org/10.1016/j.molp.2020.02.012</a>
  chicago: Moulinier-Anzola, Jeanette, Maximilian Schwihla, Lucinda De-Araújo, Christina
    Artner, Lisa Jörg, Nataliia Konstantinova, Christian Luschnig, and Barbara Korbei.
    “TOLs Function as Ubiquitin Receptors in the Early Steps of the ESCRT Pathway
    in Higher Plants.” <i>Molecular Plant</i>. Elsevier, 2020. <a href="https://doi.org/10.1016/j.molp.2020.02.012">https://doi.org/10.1016/j.molp.2020.02.012</a>.
  ieee: J. Moulinier-Anzola <i>et al.</i>, “TOLs function as ubiquitin receptors in
    the early steps of the ESCRT pathway in higher plants,” <i>Molecular Plant</i>,
    vol. 13, no. 5. Elsevier, pp. 717–731, 2020.
  ista: Moulinier-Anzola J, Schwihla M, De-Araújo L, Artner C, Jörg L, Konstantinova
    N, Luschnig C, Korbei B. 2020. TOLs function as ubiquitin receptors in the early
    steps of the ESCRT pathway in higher plants. Molecular Plant. 13(5), 717–731.
  mla: Moulinier-Anzola, Jeanette, et al. “TOLs Function as Ubiquitin Receptors in
    the Early Steps of the ESCRT Pathway in Higher Plants.” <i>Molecular Plant</i>,
    vol. 13, no. 5, Elsevier, 2020, pp. 717–31, doi:<a href="https://doi.org/10.1016/j.molp.2020.02.012">10.1016/j.molp.2020.02.012</a>.
  short: J. Moulinier-Anzola, M. Schwihla, L. De-Araújo, C. Artner, L. Jörg, N. Konstantinova,
    C. Luschnig, B. Korbei, Molecular Plant 13 (2020) 717–731.
date_created: 2024-02-28T08:55:56Z
date_published: 2020-05-04T00:00:00Z
date_updated: 2024-02-28T12:41:52Z
day: '04'
ddc:
- '580'
department:
- _id: EvBe
doi: 10.1016/j.molp.2020.02.012
external_id:
  pmid:
  - '32087370'
file:
- access_level: open_access
  checksum: c538a5008f7827f62d17d40a3bfabe65
  content_type: application/pdf
  creator: dernst
  date_created: 2024-02-28T12:39:56Z
  date_updated: 2024-02-28T12:39:56Z
  file_id: '15038'
  file_name: 2020_MolecularPlant_MoulinierAnzola.pdf
  file_size: 3089212
  relation: main_file
  success: 1
file_date_updated: 2024-02-28T12:39:56Z
has_accepted_license: '1'
intvolume: '        13'
issue: '5'
keyword:
- Plant Science
- Molecular Biology
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '05'
oa: 1
oa_version: Published Version
page: 717-731
pmid: 1
publication: Molecular Plant
publication_identifier:
  issn:
  - 1674-2052
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: TOLs function as ubiquitin receptors in the early steps of the ESCRT pathway
  in higher plants
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2020'
...
---
_id: '15055'
abstract:
- lang: eng
  text: <jats:p>Markov decision processes (MDPs) are the defacto framework for sequential
    decision making in the presence of stochastic uncertainty. A classical optimization
    criterion for MDPs is to maximize the expected discounted-sum payoff, which ignores
    low probability catastrophic events with highly negative impact on the system.
    On the other hand, risk-averse policies require the probability of undesirable
    events to be below a given threshold, but they do not account for optimization
    of the expected payoff. We consider MDPs with discounted-sum payoff with failure
    states which represent catastrophic outcomes. The objective of risk-constrained
    planning is to maximize the expected discounted-sum payoff among risk-averse policies
    that ensure the probability to encounter a failure state is below a desired threshold.
    Our main contribution is an efficient risk-constrained planning algorithm that
    combines UCT-like search with a predictor learned through interaction with the
    MDP (in the style of AlphaZero) and with a risk-constrained action selection via
    linear programming. We demonstrate the effectiveness of our approach with experiments
    on classical MDPs from the literature, including benchmarks with an order of 106
    states.</jats:p>
acknowledgement: Krishnendu Chatterjee is supported by the Austrian Science Fund (FWF)
  NFN Grant No. S11407-N23 (RiSE/SHiNE), and COST Action GAMENET. Tomas Brazdil is
  supported by the Grant Agency of Masaryk University grant no. MUNI/G/0739/2017 and
  by the Czech Science Foundation grant No. 18-11193S. Petr Novotny and Jirı Vahala
  are supported by the Czech Science Foundation grant No. GJ19-15134Y.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Tomáš
  full_name: Brázdil, Tomáš
  last_name: Brázdil
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Petr
  full_name: Novotný, Petr
  last_name: Novotný
- first_name: Jiří
  full_name: Vahala, Jiří
  last_name: Vahala
citation:
  ama: Brázdil T, Chatterjee K, Novotný P, Vahala J. Reinforcement learning of risk-constrained
    policies in Markov decision processes. <i>Proceedings of the 34th AAAI Conference
    on Artificial Intelligence</i>. 2020;34(06):9794-9801. doi:<a href="https://doi.org/10.1609/aaai.v34i06.6531">10.1609/aaai.v34i06.6531</a>
  apa: 'Brázdil, T., Chatterjee, K., Novotný, P., &#38; Vahala, J. (2020). Reinforcement
    learning of risk-constrained policies in Markov decision processes. <i>Proceedings
    of the 34th AAAI Conference on Artificial Intelligence</i>. New York, NY, United
    States: Association for the Advancement of Artificial Intelligence. <a href="https://doi.org/10.1609/aaai.v34i06.6531">https://doi.org/10.1609/aaai.v34i06.6531</a>'
  chicago: Brázdil, Tomáš, Krishnendu Chatterjee, Petr Novotný, and Jiří Vahala. “Reinforcement
    Learning of Risk-Constrained Policies in Markov Decision Processes.” <i>Proceedings
    of the 34th AAAI Conference on Artificial Intelligence</i>. Association for the
    Advancement of Artificial Intelligence, 2020. <a href="https://doi.org/10.1609/aaai.v34i06.6531">https://doi.org/10.1609/aaai.v34i06.6531</a>.
  ieee: T. Brázdil, K. Chatterjee, P. Novotný, and J. Vahala, “Reinforcement learning
    of risk-constrained policies in Markov decision processes,” <i>Proceedings of
    the 34th AAAI Conference on Artificial Intelligence</i>, vol. 34, no. 06. Association
    for the Advancement of Artificial Intelligence, pp. 9794–9801, 2020.
  ista: Brázdil T, Chatterjee K, Novotný P, Vahala J. 2020. Reinforcement learning
    of risk-constrained policies in Markov decision processes. Proceedings of the
    34th AAAI Conference on Artificial Intelligence. 34(06), 9794–9801.
  mla: Brázdil, Tomáš, et al. “Reinforcement Learning of Risk-Constrained Policies
    in Markov Decision Processes.” <i>Proceedings of the 34th AAAI Conference on Artificial
    Intelligence</i>, vol. 34, no. 06, Association for the Advancement of Artificial
    Intelligence, 2020, pp. 9794–801, doi:<a href="https://doi.org/10.1609/aaai.v34i06.6531">10.1609/aaai.v34i06.6531</a>.
  short: T. Brázdil, K. Chatterjee, P. Novotný, J. Vahala, Proceedings of the 34th
    AAAI Conference on Artificial Intelligence 34 (2020) 9794–9801.
conference:
  end_date: 2020-02-12
  location: New York, NY, United States
  name: 'AAAI: Conference on Artificial Intelligence'
  start_date: 2020-02-07
date_created: 2024-03-04T08:07:22Z
date_published: 2020-04-03T00:00:00Z
date_updated: 2024-03-04T08:30:16Z
day: '03'
department:
- _id: KrCh
doi: 10.1609/aaai.v34i06.6531
external_id:
  arxiv:
  - '2002.12086'
intvolume: '        34'
issue: '06'
keyword:
- General Medicine
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2002.12086
month: '04'
oa: 1
oa_version: Preprint
page: 9794-9801
project:
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
publication: Proceedings of the 34th AAAI Conference on Artificial Intelligence
publication_identifier:
  issn:
  - 2374-3468
publication_status: published
publisher: Association for the Advancement of Artificial Intelligence
quality_controlled: '1'
status: public
title: Reinforcement learning of risk-constrained policies in Markov decision processes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2020'
...
---
_id: '15057'
abstract:
- lang: eng
  text: Vaccinia virus–related kinase (VRK) is an evolutionarily conserved nuclear
    protein kinase. VRK-1, the single Caenorhabditis elegans VRK ortholog, functions
    in cell division and germline proliferation. However, the role of VRK-1 in postmitotic
    cells and adult life span remains unknown. Here, we show that VRK-1 increases
    organismal longevity by activating the cellular energy sensor, AMP-activated protein
    kinase (AMPK), via direct phosphorylation. We found that overexpression of vrk-1
    in the soma of adult C. elegans increased life span and, conversely, inhibition
    of vrk-1 decreased life span. In addition, vrk-1 was required for longevity conferred
    by mutations that inhibit C. elegans mitochondrial respiration, which requires
    AMPK. VRK-1 directly phosphorylated and up-regulated AMPK in both C. elegans and
    cultured human cells. Thus, our data show that the somatic nuclear kinase, VRK-1,
    promotes longevity through AMPK activation, and this function appears to be conserved
    between C. elegans and humans.
acknowledgement: 'This research was supported by grants NRF-2019R1A3B2067745 and NRF-2017R1A5A1015366
  funded by the Korean Government (MSIT) through the National Research Foundation
  (NRF) of Korea to S.-J.V.L. and by grant Basic Science Research Program (No. 2019R1A2C2009440)
  funded by the Korean Government (MSIT) through the NRF of Korea to K.-T.K. '
article_number: aaw7824
article_processing_charge: No
article_type: original
author:
- first_name: Sangsoon
  full_name: Park, Sangsoon
  last_name: Park
- first_name: Murat
  full_name: Artan, Murat
  id: C407B586-6052-11E9-B3AE-7006E6697425
  last_name: Artan
  orcid: 0000-0001-8945-6992
- first_name: Seung Hyun
  full_name: Han, Seung Hyun
  last_name: Han
- first_name: Hae-Eun H.
  full_name: Park, Hae-Eun H.
  last_name: Park
- first_name: Yoonji
  full_name: Jung, Yoonji
  last_name: Jung
- first_name: Ara B.
  full_name: Hwang, Ara B.
  last_name: Hwang
- first_name: Won Sik
  full_name: Shin, Won Sik
  last_name: Shin
- first_name: Kyong-Tai
  full_name: Kim, Kyong-Tai
  last_name: Kim
- first_name: Seung-Jae V.
  full_name: Lee, Seung-Jae V.
  last_name: Lee
citation:
  ama: Park S, Artan M, Han SH, et al. VRK-1 extends life span by activation of AMPK
    via phosphorylation. <i>Science Advances</i>. 2020;6(27). doi:<a href="https://doi.org/10.1126/sciadv.aaw7824">10.1126/sciadv.aaw7824</a>
  apa: Park, S., Artan, M., Han, S. H., Park, H.-E. H., Jung, Y., Hwang, A. B., …
    Lee, S.-J. V. (2020). VRK-1 extends life span by activation of AMPK via phosphorylation.
    <i>Science Advances</i>. American Association for the Advancement of Science.
    <a href="https://doi.org/10.1126/sciadv.aaw7824">https://doi.org/10.1126/sciadv.aaw7824</a>
  chicago: Park, Sangsoon, Murat Artan, Seung Hyun Han, Hae-Eun H. Park, Yoonji Jung,
    Ara B. Hwang, Won Sik Shin, Kyong-Tai Kim, and Seung-Jae V. Lee. “VRK-1 Extends
    Life Span by Activation of AMPK via Phosphorylation.” <i>Science Advances</i>.
    American Association for the Advancement of Science, 2020. <a href="https://doi.org/10.1126/sciadv.aaw7824">https://doi.org/10.1126/sciadv.aaw7824</a>.
  ieee: S. Park <i>et al.</i>, “VRK-1 extends life span by activation of AMPK via
    phosphorylation,” <i>Science Advances</i>, vol. 6, no. 27. American Association
    for the Advancement of Science, 2020.
  ista: Park S, Artan M, Han SH, Park H-EH, Jung Y, Hwang AB, Shin WS, Kim K-T, Lee
    S-JV. 2020. VRK-1 extends life span by activation of AMPK via phosphorylation.
    Science Advances. 6(27), aaw7824.
  mla: Park, Sangsoon, et al. “VRK-1 Extends Life Span by Activation of AMPK via Phosphorylation.”
    <i>Science Advances</i>, vol. 6, no. 27, aaw7824, American Association for the
    Advancement of Science, 2020, doi:<a href="https://doi.org/10.1126/sciadv.aaw7824">10.1126/sciadv.aaw7824</a>.
  short: S. Park, M. Artan, S.H. Han, H.-E.H. Park, Y. Jung, A.B. Hwang, W.S. Shin,
    K.-T. Kim, S.-J.V. Lee, Science Advances 6 (2020).
date_created: 2024-03-04T09:41:57Z
date_published: 2020-07-01T00:00:00Z
date_updated: 2024-03-04T09:52:09Z
day: '01'
ddc:
- '570'
department:
- _id: MaDe
doi: 10.1126/sciadv.aaw7824
file:
- access_level: open_access
  checksum: a37157cd0de709dce5fe03f4a31cd0b6
  content_type: application/pdf
  creator: dernst
  date_created: 2024-03-04T09:46:41Z
  date_updated: 2024-03-04T09:46:41Z
  file_id: '15058'
  file_name: 2020_ScienceAdvances_Park.pdf
  file_size: 1864415
  relation: main_file
  success: 1
file_date_updated: 2024-03-04T09:46:41Z
has_accepted_license: '1'
intvolume: '         6'
issue: '27'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '07'
oa: 1
oa_version: Published Version
publication: Science Advances
publication_identifier:
  eissn:
  - 2375-2548
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
status: public
title: VRK-1 extends life span by activation of AMPK via phosphorylation
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2020'
...
---
_id: '15059'
abstract:
- lang: eng
  text: "In this paper we present a room temperature radiometer that can eliminate
    the need of using cryostats in satellite payload reducing its weight and improving
    reliability. The proposed radiometer is based on an electro-optic upconverter
    that boosts up microwave photons energy by upconverting them into an optical domain
    what makes them immune to thermal noise even if operating at room temperature.
    The converter uses a high-quality factor whispering gallery\r\nmode (WGM) resonator
    providing naturally narrow bandwidth and therefore might be useful for applications
    like microwave hyperspectral sensing. The upconversion process is explained by\r\nproviding
    essential information about photon conversion efficiency and sensitivity. To prove
    the concept, we describe an experiment which shows state-of-the-art photon conversion
    efficiency n=10-5 per mW of pump power at the frequency of 80 GHz."
acknowledgement: This work has been financially supported by Comunidad de Madrid S2018/NMT-4333
  ARTINLARA-CM projects, and “FUNDACIÓN SENER” REFTA projects.
article_processing_charge: No
author:
- first_name: Michal
  full_name: Wasiak, Michal
  last_name: Wasiak
- first_name: Gabriel Santamaria
  full_name: Botello, Gabriel Santamaria
  last_name: Botello
- first_name: Kerlos Atia
  full_name: Abdalmalak, Kerlos Atia
  last_name: Abdalmalak
- first_name: Florian
  full_name: Sedlmeir, Florian
  last_name: Sedlmeir
- first_name: Alfredo R
  full_name: Rueda Sanchez, Alfredo R
  id: 3B82B0F8-F248-11E8-B48F-1D18A9856A87
  last_name: Rueda Sanchez
  orcid: 0000-0001-6249-5860
- first_name: Daniel
  full_name: Segovia-Vargas, Daniel
  last_name: Segovia-Vargas
- first_name: Harald G. L.
  full_name: Schwefel, Harald G. L.
  last_name: Schwefel
- first_name: Luis Enrique Garcia
  full_name: Munoz, Luis Enrique Garcia
  last_name: Munoz
citation:
  ama: 'Wasiak M, Botello GS, Abdalmalak KA, et al. Compact millimeter and submillimeter-wave
    photonic radiometer for cubesats. In: <i>14th European Conference on Antennas
    and Propagation</i>. IEEE; 2020. doi:<a href="https://doi.org/10.23919/eucap48036.2020.9135962">10.23919/eucap48036.2020.9135962</a>'
  apa: 'Wasiak, M., Botello, G. S., Abdalmalak, K. A., Sedlmeir, F., Rueda Sanchez,
    A. R., Segovia-Vargas, D., … Munoz, L. E. G. (2020). Compact millimeter and submillimeter-wave
    photonic radiometer for cubesats. In <i>14th European Conference on Antennas and
    Propagation</i>. Copenhagen, Denmark: IEEE. <a href="https://doi.org/10.23919/eucap48036.2020.9135962">https://doi.org/10.23919/eucap48036.2020.9135962</a>'
  chicago: Wasiak, Michal, Gabriel Santamaria Botello, Kerlos Atia Abdalmalak, Florian
    Sedlmeir, Alfredo R Rueda Sanchez, Daniel Segovia-Vargas, Harald G. L. Schwefel,
    and Luis Enrique Garcia Munoz. “Compact Millimeter and Submillimeter-Wave Photonic
    Radiometer for Cubesats.” In <i>14th European Conference on Antennas and Propagation</i>.
    IEEE, 2020. <a href="https://doi.org/10.23919/eucap48036.2020.9135962">https://doi.org/10.23919/eucap48036.2020.9135962</a>.
  ieee: M. Wasiak <i>et al.</i>, “Compact millimeter and submillimeter-wave photonic
    radiometer for cubesats,” in <i>14th European Conference on Antennas and Propagation</i>,
    Copenhagen, Denmark, 2020.
  ista: 'Wasiak M, Botello GS, Abdalmalak KA, Sedlmeir F, Rueda Sanchez AR, Segovia-Vargas
    D, Schwefel HGL, Munoz LEG. 2020. Compact millimeter and submillimeter-wave photonic
    radiometer for cubesats. 14th European Conference on Antennas and Propagation.
    EuCAP: European Conference on Antennas and Propagation.'
  mla: Wasiak, Michal, et al. “Compact Millimeter and Submillimeter-Wave Photonic
    Radiometer for Cubesats.” <i>14th European Conference on Antennas and Propagation</i>,
    IEEE, 2020, doi:<a href="https://doi.org/10.23919/eucap48036.2020.9135962">10.23919/eucap48036.2020.9135962</a>.
  short: M. Wasiak, G.S. Botello, K.A. Abdalmalak, F. Sedlmeir, A.R. Rueda Sanchez,
    D. Segovia-Vargas, H.G.L. Schwefel, L.E.G. Munoz, in:, 14th European Conference
    on Antennas and Propagation, IEEE, 2020.
conference:
  end_date: 2020-03-20
  location: Copenhagen, Denmark
  name: 'EuCAP: European Conference on Antennas and Propagation'
  start_date: 2020-03-15
date_created: 2024-03-04T09:57:48Z
date_published: 2020-07-08T00:00:00Z
date_updated: 2024-03-04T10:02:49Z
day: '08'
department:
- _id: JoFi
doi: 10.23919/eucap48036.2020.9135962
language:
- iso: eng
month: '07'
oa_version: None
publication: 14th European Conference on Antennas and Propagation
publication_identifier:
  eisbn:
  - '9788831299008'
publication_status: published
publisher: IEEE
quality_controlled: '1'
status: public
title: Compact millimeter and submillimeter-wave photonic radiometer for cubesats
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '15061'
abstract:
- lang: eng
  text: The actin cytoskeleton, a dynamic network of actin filaments and associated
    F-actin–binding proteins, is fundamentally important in eukaryotes. α-Actinins
    are major F-actin bundlers that are inhibited by Ca2+ in nonmuscle cells. Here
    we report the mechanism of Ca2+-mediated regulation of Entamoeba histolytica α-actinin-2
    (EhActn2) with features expected for the common ancestor of Entamoeba and higher
    eukaryotic α-actinins. Crystal structures of Ca2+-free and Ca2+-bound EhActn2
    reveal a calmodulin-like domain (CaMD) uniquely inserted within the rod domain.
    Integrative studies reveal an exceptionally high affinity of the EhActn2 CaMD
    for Ca2+, binding of which can only be regulated in the presence of physiological
    concentrations of Mg2+. Ca2+ binding triggers an increase in protein multidomain
    rigidity, reducing conformational flexibility of F-actin–binding domains via interdomain
    cross-talk and consequently inhibiting F-actin bundling. In vivo studies uncover
    that EhActn2 plays an important role in phagocytic cup formation and might constitute
    a new drug target for amoebic dysentery.
acknowledged_ssus:
- _id: LifeSc
acknowledgement: "We thank the staff of the macromolecular crystallography (MX) and
  SAXS beamlines at the European Synchrotron Radiation facility, Diamond, and Swiss
  Light Source for excellent support, and the Life Sciences Facility of the Institute
  of Science and Technology Austria for usage of the rheometer. We thank Life Sciences
  editors for editing assistance. EM data were\r\nrecorded at the EM Facility of the
  Vienna BioCenter Core Facilities (Austria). Confocal microscopy was carried out
  at the Advanced Instrument Research Facility, Jawaharlal Nehru University. K.D.-C.’s
  research was supported by the Initial Training Network MUZIC (ITN-MUZIC) (N°238423),
  Austrian Science Fund (FWF) Projects I525, I1593, P22276, P19060, and W1221, Laura
  Bassi Centre of Optimized Structural Studies (N°253275), a Wellcome Trust Collaborative
  Award (201543/Z/16/Z), COST Action BM1405, Vienna Science and Technology Fund (WWTF)
  Chemical Biology Project LS17-008, and Christian Doppler Laboratory for High-Content
  Structural Biology and Biotechnology. K.Z., J.L.A., C.S., E.A.G., and A.S. were
  supported by the University of Vienna, J.K. by a Wellcome Trust Collaborative Award
  and by the Centre of Optimized Structural Studies, M.P. by FWF Project I1593, E.d.A.R.
  ITN-MUZIC, and FWF Projects I525 and I1593, and T.C.M. and L.C. by FWF Project I
  2408-B22. E.A.G. acknowledges the PhD program Structure and Interaction of Biological
  Macromolecules. M.B. acknowledges the University Grant Commission, India, for a
  senior research fellowship. A.B. acknowledges a JC Bose Fellowship from the Science
  Engineering Research Council. "
article_processing_charge: No
article_type: original
author:
- first_name: Nikos
  full_name: Pinotsis, Nikos
  last_name: Pinotsis
- first_name: Karolina
  full_name: Zielinska, Karolina
  last_name: Zielinska
- first_name: Mrigya
  full_name: Babuta, Mrigya
  last_name: Babuta
- first_name: Joan L.
  full_name: Arolas, Joan L.
  last_name: Arolas
- first_name: Julius
  full_name: Kostan, Julius
  last_name: Kostan
- first_name: Muhammad Bashir
  full_name: Khan, Muhammad Bashir
  last_name: Khan
- first_name: Claudia
  full_name: Schreiner, Claudia
  last_name: Schreiner
- first_name: Anita P
  full_name: Testa Salmazo, Anita P
  id: 41F1F098-F248-11E8-B48F-1D18A9856A87
  last_name: Testa Salmazo
- first_name: Luciano
  full_name: Ciccarelli, Luciano
  last_name: Ciccarelli
- first_name: Martin
  full_name: Puchinger, Martin
  last_name: Puchinger
- first_name: Eirini A.
  full_name: Gkougkoulia, Eirini A.
  last_name: Gkougkoulia
- first_name: Euripedes de Almeida
  full_name: Ribeiro, Euripedes de Almeida
  last_name: Ribeiro
- first_name: Thomas C.
  full_name: Marlovits, Thomas C.
  last_name: Marlovits
- first_name: Alok
  full_name: Bhattacharya, Alok
  last_name: Bhattacharya
- first_name: Kristina
  full_name: Djinovic-Carugo, Kristina
  last_name: Djinovic-Carugo
citation:
  ama: Pinotsis N, Zielinska K, Babuta M, et al. Calcium modulates the domain flexibility
    and function of an α-actinin similar to the ancestral α-actinin. <i>Proceedings
    of the National Academy of Sciences</i>. 2020;117(36):22101-22112. doi:<a href="https://doi.org/10.1073/pnas.1917269117">10.1073/pnas.1917269117</a>
  apa: Pinotsis, N., Zielinska, K., Babuta, M., Arolas, J. L., Kostan, J., Khan, M.
    B., … Djinovic-Carugo, K. (2020). Calcium modulates the domain flexibility and
    function of an α-actinin similar to the ancestral α-actinin. <i>Proceedings of
    the National Academy of Sciences</i>. Proceedings of the National Academy of Sciences.
    <a href="https://doi.org/10.1073/pnas.1917269117">https://doi.org/10.1073/pnas.1917269117</a>
  chicago: Pinotsis, Nikos, Karolina Zielinska, Mrigya Babuta, Joan L. Arolas, Julius
    Kostan, Muhammad Bashir Khan, Claudia Schreiner, et al. “Calcium Modulates the
    Domain Flexibility and Function of an α-Actinin Similar to the Ancestral α-Actinin.”
    <i>Proceedings of the National Academy of Sciences</i>. Proceedings of the National
    Academy of Sciences, 2020. <a href="https://doi.org/10.1073/pnas.1917269117">https://doi.org/10.1073/pnas.1917269117</a>.
  ieee: N. Pinotsis <i>et al.</i>, “Calcium modulates the domain flexibility and function
    of an α-actinin similar to the ancestral α-actinin,” <i>Proceedings of the National
    Academy of Sciences</i>, vol. 117, no. 36. Proceedings of the National Academy
    of Sciences, pp. 22101–22112, 2020.
  ista: Pinotsis N, Zielinska K, Babuta M, Arolas JL, Kostan J, Khan MB, Schreiner
    C, Testa Salmazo AP, Ciccarelli L, Puchinger M, Gkougkoulia EA, Ribeiro E de A,
    Marlovits TC, Bhattacharya A, Djinovic-Carugo K. 2020. Calcium modulates the domain
    flexibility and function of an α-actinin similar to the ancestral α-actinin. Proceedings
    of the National Academy of Sciences. 117(36), 22101–22112.
  mla: Pinotsis, Nikos, et al. “Calcium Modulates the Domain Flexibility and Function
    of an α-Actinin Similar to the Ancestral α-Actinin.” <i>Proceedings of the National
    Academy of Sciences</i>, vol. 117, no. 36, Proceedings of the National Academy
    of Sciences, 2020, pp. 22101–12, doi:<a href="https://doi.org/10.1073/pnas.1917269117">10.1073/pnas.1917269117</a>.
  short: N. Pinotsis, K. Zielinska, M. Babuta, J.L. Arolas, J. Kostan, M.B. Khan,
    C. Schreiner, A.P. Testa Salmazo, L. Ciccarelli, M. Puchinger, E.A. Gkougkoulia,
    E. de A. Ribeiro, T.C. Marlovits, A. Bhattacharya, K. Djinovic-Carugo, Proceedings
    of the National Academy of Sciences 117 (2020) 22101–22112.
date_created: 2024-03-04T10:03:52Z
date_published: 2020-09-08T00:00:00Z
date_updated: 2024-03-04T10:14:44Z
day: '08'
department:
- _id: CaBe
doi: 10.1073/pnas.1917269117
external_id:
  pmid:
  - '32848067'
intvolume: '       117'
issue: '36'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1073/pnas.191726911
month: '09'
oa: 1
oa_version: Published Version
page: 22101-22112
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
  eissn:
  - 1091-6490
  issn:
  - 0027-8424
publication_status: published
publisher: Proceedings of the National Academy of Sciences
quality_controlled: '1'
status: public
title: Calcium modulates the domain flexibility and function of an α-actinin similar
  to the ancestral α-actinin
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 117
year: '2020'
...
---
_id: '15063'
abstract:
- lang: eng
  text: We consider the least singular value of a large random matrix with real or
    complex i.i.d. Gaussian entries shifted by a constant z∈C. We prove an optimal
    lower tail estimate on this singular value in the critical regime where z is around
    the spectral edge, thus improving the classical bound of Sankar, Spielman and
    Teng (SIAM J. Matrix Anal. Appl. 28:2 (2006), 446–476) for the particular shift-perturbation
    in the edge regime. Lacking Brézin–Hikami formulas in the real case, we rely on
    the superbosonization formula (Comm. Math. Phys. 283:2 (2008), 343–395).
acknowledgement: Partially supported by ERC Advanced Grant No. 338804. This project
  has received funding from the European Union’s Horizon 2020 research and innovation
  programme under the Marie Sklodowska-Curie Grant Agreement No. 66538
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Giorgio
  full_name: Cipolloni, Giorgio
  id: 42198EFA-F248-11E8-B48F-1D18A9856A87
  last_name: Cipolloni
  orcid: 0000-0002-4901-7992
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Dominik J
  full_name: Schröder, Dominik J
  id: 408ED176-F248-11E8-B48F-1D18A9856A87
  last_name: Schröder
  orcid: 0000-0002-2904-1856
citation:
  ama: Cipolloni G, Erdös L, Schröder DJ. Optimal lower bound on the least singular
    value of the shifted Ginibre ensemble. <i>Probability and Mathematical Physics</i>.
    2020;1(1):101-146. doi:<a href="https://doi.org/10.2140/pmp.2020.1.101">10.2140/pmp.2020.1.101</a>
  apa: Cipolloni, G., Erdös, L., &#38; Schröder, D. J. (2020). Optimal lower bound
    on the least singular value of the shifted Ginibre ensemble. <i>Probability and
    Mathematical Physics</i>. Mathematical Sciences Publishers. <a href="https://doi.org/10.2140/pmp.2020.1.101">https://doi.org/10.2140/pmp.2020.1.101</a>
  chicago: Cipolloni, Giorgio, László Erdös, and Dominik J Schröder. “Optimal Lower
    Bound on the Least Singular Value of the Shifted Ginibre Ensemble.” <i>Probability
    and Mathematical Physics</i>. Mathematical Sciences Publishers, 2020. <a href="https://doi.org/10.2140/pmp.2020.1.101">https://doi.org/10.2140/pmp.2020.1.101</a>.
  ieee: G. Cipolloni, L. Erdös, and D. J. Schröder, “Optimal lower bound on the least
    singular value of the shifted Ginibre ensemble,” <i>Probability and Mathematical
    Physics</i>, vol. 1, no. 1. Mathematical Sciences Publishers, pp. 101–146, 2020.
  ista: Cipolloni G, Erdös L, Schröder DJ. 2020. Optimal lower bound on the least
    singular value of the shifted Ginibre ensemble. Probability and Mathematical Physics.
    1(1), 101–146.
  mla: Cipolloni, Giorgio, et al. “Optimal Lower Bound on the Least Singular Value
    of the Shifted Ginibre Ensemble.” <i>Probability and Mathematical Physics</i>,
    vol. 1, no. 1, Mathematical Sciences Publishers, 2020, pp. 101–46, doi:<a href="https://doi.org/10.2140/pmp.2020.1.101">10.2140/pmp.2020.1.101</a>.
  short: G. Cipolloni, L. Erdös, D.J. Schröder, Probability and Mathematical Physics
    1 (2020) 101–146.
date_created: 2024-03-04T10:27:57Z
date_published: 2020-11-16T00:00:00Z
date_updated: 2024-03-04T10:33:15Z
day: '16'
department:
- _id: LaEr
doi: 10.2140/pmp.2020.1.101
ec_funded: 1
external_id:
  arxiv:
  - '1908.01653'
intvolume: '         1'
issue: '1'
keyword:
- General Medicine
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.1908.01653
month: '11'
oa: 1
oa_version: Preprint
page: 101-146
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication: Probability and Mathematical Physics
publication_identifier:
  issn:
  - 2690-1005
  - 2690-0998
publication_status: published
publisher: Mathematical Sciences Publishers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Optimal lower bound on the least singular value of the shifted Ginibre ensemble
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1
year: '2020'
...
---
_id: '15064'
abstract:
- lang: eng
  text: We call a continuous self-map that reveals itself through a discrete set of
    point-value pairs a sampled dynamical system. Capturing the available information
    with chain maps on Delaunay complexes, we use persistent homology to quantify
    the evidence of recurrent behavior. We establish a sampling theorem to recover
    the eigenspaces of the endomorphism on homology induced by the self-map. Using
    a combinatorial gradient flow arising from the discrete Morse theory for Čech
    and Delaunay complexes, we construct a chain map to transform the problem from
    the natural but expensive Čech complexes to the computationally efficient Delaunay
    triangulations. The fast chain map algorithm has applications beyond dynamical
    systems.
acknowledgement: This research has been supported by the DFG Collaborative Research
  Center SFB/TRR 109 “Discretization in Geometry and Dynamics”, by Polish MNiSzW Grant
  No. 2621/7.PR/12/2013/2, by the Polish National Science Center under Maestro Grant
  No. 2014/14/A/ST1/00453 and Grant No. DEC-2013/09/N/ST6/02995. Open Access funding
  provided by Projekt DEAL.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: U.
  full_name: Bauer, U.
  last_name: Bauer
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Grzegorz
  full_name: Jablonski, Grzegorz
  id: 4483EF78-F248-11E8-B48F-1D18A9856A87
  last_name: Jablonski
  orcid: 0000-0002-3536-9866
- first_name: M.
  full_name: Mrozek, M.
  last_name: Mrozek
citation:
  ama: Bauer U, Edelsbrunner H, Jablonski G, Mrozek M. Čech-Delaunay gradient flow
    and homology inference for self-maps. <i>Journal of Applied and Computational
    Topology</i>. 2020;4(4):455-480. doi:<a href="https://doi.org/10.1007/s41468-020-00058-8">10.1007/s41468-020-00058-8</a>
  apa: Bauer, U., Edelsbrunner, H., Jablonski, G., &#38; Mrozek, M. (2020). Čech-Delaunay
    gradient flow and homology inference for self-maps. <i>Journal of Applied and
    Computational Topology</i>. Springer Nature. <a href="https://doi.org/10.1007/s41468-020-00058-8">https://doi.org/10.1007/s41468-020-00058-8</a>
  chicago: Bauer, U., Herbert Edelsbrunner, Grzegorz Jablonski, and M. Mrozek. “Čech-Delaunay
    Gradient Flow and Homology Inference for Self-Maps.” <i>Journal of Applied and
    Computational Topology</i>. Springer Nature, 2020. <a href="https://doi.org/10.1007/s41468-020-00058-8">https://doi.org/10.1007/s41468-020-00058-8</a>.
  ieee: U. Bauer, H. Edelsbrunner, G. Jablonski, and M. Mrozek, “Čech-Delaunay gradient
    flow and homology inference for self-maps,” <i>Journal of Applied and Computational
    Topology</i>, vol. 4, no. 4. Springer Nature, pp. 455–480, 2020.
  ista: Bauer U, Edelsbrunner H, Jablonski G, Mrozek M. 2020. Čech-Delaunay gradient
    flow and homology inference for self-maps. Journal of Applied and Computational
    Topology. 4(4), 455–480.
  mla: Bauer, U., et al. “Čech-Delaunay Gradient Flow and Homology Inference for Self-Maps.”
    <i>Journal of Applied and Computational Topology</i>, vol. 4, no. 4, Springer
    Nature, 2020, pp. 455–80, doi:<a href="https://doi.org/10.1007/s41468-020-00058-8">10.1007/s41468-020-00058-8</a>.
  short: U. Bauer, H. Edelsbrunner, G. Jablonski, M. Mrozek, Journal of Applied and
    Computational Topology 4 (2020) 455–480.
date_created: 2024-03-04T10:47:49Z
date_published: 2020-12-01T00:00:00Z
date_updated: 2024-03-04T10:54:04Z
day: '01'
ddc:
- '500'
department:
- _id: HeEd
doi: 10.1007/s41468-020-00058-8
file:
- access_level: open_access
  checksum: eed1168b6e66cd55272c19bb7fca8a1c
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  creator: dernst
  date_created: 2024-03-04T10:52:42Z
  date_updated: 2024-03-04T10:52:42Z
  file_id: '15065'
  file_name: 2020_JourApplCompTopology_Bauer.pdf
  file_size: 851190
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intvolume: '         4'
issue: '4'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 455-480
publication: Journal of Applied and Computational Topology
publication_identifier:
  eissn:
  - 2367-1734
  issn:
  - 2367-1726
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Čech-Delaunay gradient flow and homology inference for self-maps
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2020'
...
---
_id: '15074'
abstract:
- lang: eng
  text: We introduce a new graph problem, the token dropping game, and we show how
    to solve it efficiently in a distributed setting. We use the token dropping game
    as a tool to design an efficient distributed algorithm for the stable orientation
    problem, which is a special case of the more general locally optimal semi-matching
    problem. The prior work by Czygrinow et al. (DISC 2012) finds a locally optimal
    semi-matching in O(Δ⁵) rounds in graphs of maximum degree Δ, which directly implies
    an algorithm with the same runtime for stable orientations. We improve the runtime
    to O(Δ⁴) for stable orientations and prove a lower bound of Ω(Δ) rounds.
alternative_title:
- LIPIcs
article_number: '40'
article_processing_charge: No
arxiv: 1
author:
- first_name: Sebastian
  full_name: Brandt, Sebastian
  last_name: Brandt
- first_name: Barbara
  full_name: Keller, Barbara
  last_name: Keller
- first_name: Joel
  full_name: Rybicki, Joel
  id: 334EFD2E-F248-11E8-B48F-1D18A9856A87
  last_name: Rybicki
  orcid: 0000-0002-6432-6646
- first_name: Jukka
  full_name: Suomela, Jukka
  last_name: Suomela
- first_name: Jara
  full_name: Uitto, Jara
  last_name: Uitto
citation:
  ama: 'Brandt S, Keller B, Rybicki J, Suomela J, Uitto J. Brief announcement: Efficient
    load-balancing through distributed token dropping. In: <i>34th International Symposium
    on Distributed Computing</i>. Vol 179. Schloss Dagstuhl - Leibniz-Zentrum für
    Informatik; 2020. doi:<a href="https://doi.org/10.4230/LIPIcs.DISC.2020.40">10.4230/LIPIcs.DISC.2020.40</a>'
  apa: 'Brandt, S., Keller, B., Rybicki, J., Suomela, J., &#38; Uitto, J. (2020).
    Brief announcement: Efficient load-balancing through distributed token dropping.
    In <i>34th International Symposium on Distributed Computing</i> (Vol. 179). Virtual:
    Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href="https://doi.org/10.4230/LIPIcs.DISC.2020.40">https://doi.org/10.4230/LIPIcs.DISC.2020.40</a>'
  chicago: 'Brandt, Sebastian, Barbara Keller, Joel Rybicki, Jukka Suomela, and Jara
    Uitto. “Brief Announcement: Efficient Load-Balancing through Distributed Token
    Dropping.” In <i>34th International Symposium on Distributed Computing</i>, Vol.
    179. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2020. <a href="https://doi.org/10.4230/LIPIcs.DISC.2020.40">https://doi.org/10.4230/LIPIcs.DISC.2020.40</a>.'
  ieee: 'S. Brandt, B. Keller, J. Rybicki, J. Suomela, and J. Uitto, “Brief announcement:
    Efficient load-balancing through distributed token dropping,” in <i>34th International
    Symposium on Distributed Computing</i>, Virtual, 2020, vol. 179.'
  ista: 'Brandt S, Keller B, Rybicki J, Suomela J, Uitto J. 2020. Brief announcement:
    Efficient load-balancing through distributed token dropping. 34th International
    Symposium on Distributed Computing. DISC: Symposium on Distributed Computing,
    LIPIcs, vol. 179, 40.'
  mla: 'Brandt, Sebastian, et al. “Brief Announcement: Efficient Load-Balancing through
    Distributed Token Dropping.” <i>34th International Symposium on Distributed Computing</i>,
    vol. 179, 40, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2020, doi:<a
    href="https://doi.org/10.4230/LIPIcs.DISC.2020.40">10.4230/LIPIcs.DISC.2020.40</a>.'
  short: S. Brandt, B. Keller, J. Rybicki, J. Suomela, J. Uitto, in:, 34th International
    Symposium on Distributed Computing, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2020.
conference:
  end_date: 2020-10-16
  location: Virtual
  name: 'DISC: Symposium on Distributed Computing'
  start_date: 2020-10-12
date_created: 2024-03-05T07:09:12Z
date_published: 2020-10-07T00:00:00Z
date_updated: 2024-03-05T07:13:13Z
day: '07'
ddc:
- '000'
department:
- _id: DaAl
doi: 10.4230/LIPIcs.DISC.2020.40
external_id:
  arxiv:
  - '2005.07761'
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  checksum: 23e2d9321aef53092dc1e24a8ab82d72
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  date_created: 2024-03-05T07:08:27Z
  date_updated: 2024-03-05T07:08:27Z
  file_id: '15075'
  file_name: 2020_LIPIcs_Brandt.pdf
  file_size: 303529
  relation: main_file
  success: 1
file_date_updated: 2024-03-05T07:08:27Z
has_accepted_license: '1'
intvolume: '       179'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/3.0/
month: '10'
oa: 1
oa_version: Published Version
publication: 34th International Symposium on Distributed Computing
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
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    status: public
scopus_import: '1'
status: public
title: 'Brief announcement: Efficient load-balancing through distributed token dropping'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/3.0/legalcode
  name: Creative Commons Attribution 3.0 Unported (CC BY 3.0)
  short: CC BY (3.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 179
year: '2020'
...
---
_id: '15077'
abstract:
- lang: eng
  text: "We consider the following dynamic load-balancing process: given an underlying
    graph G with n nodes, in each step t≥ 0, one unit of load is created, and placed
    at a randomly chosen graph node. In the same step, the chosen node picks a random
    neighbor, and the two nodes balance their loads by averaging them. We are interested
    in the expected gap between the minimum and maximum loads at nodes as the process
    progresses, and its dependence on n and on the graph structure. Variants of the
    above graphical balanced allocation process have been studied previously by Peres,
    Talwar, and Wieder [Peres et al., 2015], and by Sauerwald and Sun [Sauerwald and
    Sun, 2015]. These authors left as open the question of characterizing the gap
    in the case of cycle graphs in the dynamic case, where weights are created during
    the algorithm’s execution. For this case, the only known upper bound is of \U0001D4AA(n
    log n), following from a majorization argument due to [Peres et al., 2015], which
    analyzes a related graphical allocation process. In this paper, we provide an
    upper bound of \U0001D4AA (√n log n) on the expected gap of the above process
    for cycles of length n. We introduce a new potential analysis technique, which
    enables us to bound the difference in load between k-hop neighbors on the cycle,
    for any k ≤ n/2. We complement this with a \"gap covering\" argument, which bounds
    the maximum value of the gap by bounding its value across all possible subsets
    of a certain structure, and recursively bounding the gaps within each subset.
    We provide analytical and experimental evidence that our upper bound on the gap
    is tight up to a logarithmic factor."
acknowledgement: "The authors sincerely thank Thomas Sauerwald and George Giakkoupis
  for insightful discussions, and Mohsen Ghaffari, Yuval Peres, and Udi Wieder for
  feedback on earlier\r\nversions of this draft. We also thank the ICALP anonymous
  reviewers for their very useful comments.\r\nFunding: European Research Council
  funding award PR1042ERC01"
alternative_title:
- LIPIcs
article_number: '7'
article_processing_charge: No
arxiv: 1
author:
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
- first_name: Giorgi
  full_name: Nadiradze, Giorgi
  id: 3279A00C-F248-11E8-B48F-1D18A9856A87
  last_name: Nadiradze
  orcid: 0000-0001-5634-0731
- first_name: Amirmojtaba
  full_name: Sabour, Amirmojtaba
  id: bcc145fd-e77f-11ea-ae8b-80d661dbff67
  last_name: Sabour
citation:
  ama: 'Alistarh D-A, Nadiradze G, Sabour A. Dynamic averaging load balancing on cycles.
    In: <i>47th International Colloquium on Automata, Languages, and Programming</i>.
    Vol 168. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2020. doi:<a href="https://doi.org/10.4230/LIPIcs.ICALP.2020.7">10.4230/LIPIcs.ICALP.2020.7</a>'
  apa: 'Alistarh, D.-A., Nadiradze, G., &#38; Sabour, A. (2020). Dynamic averaging
    load balancing on cycles. In <i>47th International Colloquium on Automata, Languages,
    and Programming</i> (Vol. 168). Saarbrücken, Germany, Virtual: Schloss Dagstuhl
    - Leibniz-Zentrum für Informatik. <a href="https://doi.org/10.4230/LIPIcs.ICALP.2020.7">https://doi.org/10.4230/LIPIcs.ICALP.2020.7</a>'
  chicago: Alistarh, Dan-Adrian, Giorgi Nadiradze, and Amirmojtaba Sabour. “Dynamic
    Averaging Load Balancing on Cycles.” In <i>47th International Colloquium on Automata,
    Languages, and Programming</i>, Vol. 168. Schloss Dagstuhl - Leibniz-Zentrum für
    Informatik, 2020. <a href="https://doi.org/10.4230/LIPIcs.ICALP.2020.7">https://doi.org/10.4230/LIPIcs.ICALP.2020.7</a>.
  ieee: D.-A. Alistarh, G. Nadiradze, and A. Sabour, “Dynamic averaging load balancing
    on cycles,” in <i>47th International Colloquium on Automata, Languages, and Programming</i>,
    Saarbrücken, Germany, Virtual, 2020, vol. 168.
  ista: 'Alistarh D-A, Nadiradze G, Sabour A. 2020. Dynamic averaging load balancing
    on cycles. 47th International Colloquium on Automata, Languages, and Programming.
    ICALP: International Colloquium on Automata, Languages, and Programming, LIPIcs,
    vol. 168, 7.'
  mla: Alistarh, Dan-Adrian, et al. “Dynamic Averaging Load Balancing on Cycles.”
    <i>47th International Colloquium on Automata, Languages, and Programming</i>,
    vol. 168, 7, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2020, doi:<a href="https://doi.org/10.4230/LIPIcs.ICALP.2020.7">10.4230/LIPIcs.ICALP.2020.7</a>.
  short: D.-A. Alistarh, G. Nadiradze, A. Sabour, in:, 47th International Colloquium
    on Automata, Languages, and Programming, Schloss Dagstuhl - Leibniz-Zentrum für
    Informatik, 2020.
conference:
  end_date: 2020-07-11
  location: Saarbrücken, Germany, Virtual
  name: 'ICALP: International Colloquium on Automata, Languages, and Programming'
  start_date: 2020-07-08
date_created: 2024-03-05T07:25:37Z
date_published: 2020-06-29T00:00:00Z
date_updated: 2024-03-05T07:35:53Z
day: '29'
ddc:
- '000'
department:
- _id: DaAl
doi: 10.4230/LIPIcs.ICALP.2020.7
ec_funded: 1
external_id:
  arxiv:
  - '2003.09297'
file:
- access_level: open_access
  checksum: e5eb16199f4ccfd77a321977eb3f026f
  content_type: application/pdf
  creator: dernst
  date_created: 2024-03-05T07:25:15Z
  date_updated: 2024-03-05T07:25:15Z
  file_id: '15078'
  file_name: 2020_LIPIcs_Alistarh.pdf
  file_size: 782987
  relation: main_file
  success: 1
file_date_updated: 2024-03-05T07:25:15Z
has_accepted_license: '1'
intvolume: '       168'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
project:
- _id: 268A44D6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '805223'
  name: Elastic Coordination for Scalable Machine Learning
publication: 47th International Colloquium on Automata, Languages, and Programming
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
related_material:
  record:
  - id: '8286'
    relation: later_version
    status: public
scopus_import: '1'
status: public
title: Dynamic averaging load balancing on cycles
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/3.0/legalcode
  name: Creative Commons Attribution 3.0 Unported (CC BY 3.0)
  short: CC BY (3.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 168
year: '2020'
...
---
_id: '15082'
abstract:
- lang: eng
  text: "Two plane drawings of geometric graphs on the same set of points are called
    disjoint compatible if their union is plane and they do not have an edge in common.
    For a given set S of 2n points two plane drawings of perfect matchings M1 and
    M2 (which do not need to be disjoint nor compatible) are disjoint tree-compatible
    if there exists a plane drawing of a spanning tree T on S which is disjoint compatible
    to both M1 and M2.\r\nWe show that the graph of all disjoint tree-compatible perfect
    geometric matchings on 2n points in convex position is connected if and only if
    2n ≥ 10. Moreover, in that case the diameter\r\nof this graph is either 4 or 5,
    independent of n."
acknowledgement: Research on this work was initiated at the 6th Austrian-Japanese-Mexican-Spanish
  Workshop on Discrete Geometry and continued during the 16th European Geometric Graph-Week,
  both held near Strobl, Austria. We are grateful to the participants for the inspiring
  atmosphere. We especially thank Alexander Pilz for bringing this class of problems
  to our attention and Birgit Vogtenhuber for inspiring discussions. D.P. is partially
  supported by the FWF grant I 3340-N35 (Collaborative DACH project Arrangements and
  Drawings). The research stay of P.P. at IST Austria is funded by the project CZ.02.2.69/0.0/0.0/17_050/0008466
  Improvement of internationalization in the field of research and development at
  Charles University, through the support of quality projects MSCA-IF. This project
  has received funding from the European Union’s Horizon 2020 research and innovation
  programme under the Marie Skłodowska-Curie grant agreement No 734922.
article_number: '56'
article_processing_charge: No
author:
- first_name: Oswin
  full_name: Aichholzer, Oswin
  last_name: Aichholzer
- first_name: Julia
  full_name: Obmann, Julia
  last_name: Obmann
- first_name: Pavel
  full_name: Patak, Pavel
  id: B593B804-1035-11EA-B4F1-947645A5BB83
  last_name: Patak
- first_name: Daniel
  full_name: Perz, Daniel
  last_name: Perz
- first_name: Josef
  full_name: Tkadlec, Josef
  id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
  last_name: Tkadlec
  orcid: 0000-0002-1097-9684
citation:
  ama: 'Aichholzer O, Obmann J, Patak P, Perz D, Tkadlec J. Disjoint tree-compatible
    plane perfect matchings. In: <i>36th European Workshop on Computational Geometry</i>.
    ; 2020.'
  apa: Aichholzer, O., Obmann, J., Patak, P., Perz, D., &#38; Tkadlec, J. (2020).
    Disjoint tree-compatible plane perfect matchings. In <i>36th European Workshop
    on Computational Geometry</i>. Würzburg, Germany, Virtual.
  chicago: Aichholzer, Oswin, Julia Obmann, Pavel Patak, Daniel Perz, and Josef Tkadlec.
    “Disjoint Tree-Compatible Plane Perfect Matchings.” In <i>36th European Workshop
    on Computational Geometry</i>, 2020.
  ieee: O. Aichholzer, J. Obmann, P. Patak, D. Perz, and J. Tkadlec, “Disjoint tree-compatible
    plane perfect matchings,” in <i>36th European Workshop on Computational Geometry</i>,
    Würzburg, Germany, Virtual, 2020.
  ista: 'Aichholzer O, Obmann J, Patak P, Perz D, Tkadlec J. 2020. Disjoint tree-compatible
    plane perfect matchings. 36th European Workshop on Computational Geometry. EuroCG:
    European Workshop on Computational Geometry, 56.'
  mla: Aichholzer, Oswin, et al. “Disjoint Tree-Compatible Plane Perfect Matchings.”
    <i>36th European Workshop on Computational Geometry</i>, 56, 2020.
  short: O. Aichholzer, J. Obmann, P. Patak, D. Perz, J. Tkadlec, in:, 36th European
    Workshop on Computational Geometry, 2020.
conference:
  end_date: 2020-03-18
  location: Würzburg, Germany, Virtual
  name: 'EuroCG: European Workshop on Computational Geometry'
  start_date: 2020-03-16
date_created: 2024-03-05T08:57:17Z
date_published: 2020-04-01T00:00:00Z
date_updated: 2024-03-05T09:00:07Z
day: '01'
department:
- _id: KrCh
- _id: UlWa
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www1.pub.informatik.uni-wuerzburg.de/eurocg2020/data/uploads/papers/eurocg20_paper_56.pdf
month: '04'
oa: 1
oa_version: Published Version
publication: 36th European Workshop on Computational Geometry
publication_status: published
quality_controlled: '1'
status: public
title: Disjoint tree-compatible plane perfect matchings
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '13056'
abstract:
- lang: eng
  text: This datasets comprises all data shown in plots of the submitted article "Converting
    microwave and telecom photons with a silicon photonic nanomechanical interface".
    Additional raw data are available from the corresponding author on reasonable
    request.
article_processing_charge: No
author:
- first_name: Georg M
  full_name: Arnold, Georg M
  id: 3770C838-F248-11E8-B48F-1D18A9856A87
  last_name: Arnold
  orcid: 0000-0003-1397-7876
- first_name: Matthias
  full_name: Wulf, Matthias
  id: 45598606-F248-11E8-B48F-1D18A9856A87
  last_name: Wulf
  orcid: 0000-0001-6613-1378
- first_name: Shabir
  full_name: Barzanjeh, Shabir
  id: 2D25E1F6-F248-11E8-B48F-1D18A9856A87
  last_name: Barzanjeh
  orcid: 0000-0003-0415-1423
- first_name: Elena
  full_name: Redchenko, Elena
  id: 2C21D6E8-F248-11E8-B48F-1D18A9856A87
  last_name: Redchenko
- first_name: Alfredo R
  full_name: Rueda Sanchez, Alfredo R
  id: 3B82B0F8-F248-11E8-B48F-1D18A9856A87
  last_name: Rueda Sanchez
  orcid: 0000-0001-6249-5860
- first_name: William J
  full_name: Hease, William J
  id: 29705398-F248-11E8-B48F-1D18A9856A87
  last_name: Hease
  orcid: 0000-0001-9868-2166
- first_name: Farid
  full_name: Hassani, Farid
  id: 2AED110C-F248-11E8-B48F-1D18A9856A87
  last_name: Hassani
  orcid: 0000-0001-6937-5773
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
citation:
  ama: Arnold GM, Wulf M, Barzanjeh S, et al. Converting microwave and telecom photons
    with a silicon photonic nanomechanical interface. 2020. doi:<a href="https://doi.org/10.5281/ZENODO.3961561">10.5281/ZENODO.3961561</a>
  apa: Arnold, G. M., Wulf, M., Barzanjeh, S., Redchenko, E., Rueda Sanchez, A. R.,
    Hease, W. J., … Fink, J. M. (2020). Converting microwave and telecom photons with
    a silicon photonic nanomechanical interface. Zenodo. <a href="https://doi.org/10.5281/ZENODO.3961561">https://doi.org/10.5281/ZENODO.3961561</a>
  chicago: Arnold, Georg M, Matthias Wulf, Shabir Barzanjeh, Elena Redchenko, Alfredo
    R Rueda Sanchez, William J Hease, Farid Hassani, and Johannes M Fink. “Converting
    Microwave and Telecom Photons with a Silicon Photonic Nanomechanical Interface.”
    Zenodo, 2020. <a href="https://doi.org/10.5281/ZENODO.3961561">https://doi.org/10.5281/ZENODO.3961561</a>.
  ieee: G. M. Arnold <i>et al.</i>, “Converting microwave and telecom photons with
    a silicon photonic nanomechanical interface.” Zenodo, 2020.
  ista: Arnold GM, Wulf M, Barzanjeh S, Redchenko E, Rueda Sanchez AR, Hease WJ, Hassani
    F, Fink JM. 2020. Converting microwave and telecom photons with a silicon photonic
    nanomechanical interface, Zenodo, <a href="https://doi.org/10.5281/ZENODO.3961561">10.5281/ZENODO.3961561</a>.
  mla: Arnold, Georg M., et al. <i>Converting Microwave and Telecom Photons with a
    Silicon Photonic Nanomechanical Interface</i>. Zenodo, 2020, doi:<a href="https://doi.org/10.5281/ZENODO.3961561">10.5281/ZENODO.3961561</a>.
  short: G.M. Arnold, M. Wulf, S. Barzanjeh, E. Redchenko, A.R. Rueda Sanchez, W.J.
    Hease, F. Hassani, J.M. Fink, (2020).
date_created: 2023-05-23T13:37:41Z
date_published: 2020-07-27T00:00:00Z
date_updated: 2024-09-10T12:23:51Z
day: '27'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.5281/ZENODO.3961561
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5281/zenodo.3961562
month: '07'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
  record:
  - id: '8529'
    relation: used_in_publication
    status: public
status: public
title: Converting microwave and telecom photons with a silicon photonic nanomechanical
  interface
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '13060'
abstract:
- lang: eng
  text: Coinfections with multiple pathogens can result in complex within-host dynamics
    affecting virulence and transmission. Whilst multiple infections are intensively
    studied in solitary hosts, it is so far unresolved how social host interactions
    interfere with pathogen competition, and if this depends on coinfection diversity.
    We studied how the collective disease defenses of ants – their social immunity
    ­– influence pathogen competition in coinfections of same or different fungal
    pathogen species. Social immunity reduced virulence for all pathogen combinations,
    but interfered with spore production only in different-species coinfections. Here,
    it decreased overall pathogen sporulation success, whilst simultaneously increasing
    co-sporulation on individual cadavers and maintaining a higher pathogen diversity
    at the community-level. Mathematical modeling revealed that host sanitary care
    alone can modulate competitive outcomes between pathogens, giving advantage to
    fast-germinating, thus less grooming-sensitive ones. Host social interactions
    can hence modulate infection dynamics in coinfected group members, thereby altering
    pathogen communities at the host- and population-level.
article_processing_charge: No
author:
- first_name: Barbara
  full_name: Milutinovic, Barbara
  id: 2CDC32B8-F248-11E8-B48F-1D18A9856A87
  last_name: Milutinovic
  orcid: 0000-0002-8214-4758
- first_name: Miriam
  full_name: Stock, Miriam
  id: 42462816-F248-11E8-B48F-1D18A9856A87
  last_name: Stock
- first_name: Anna V
  full_name: Grasse, Anna V
  id: 406F989C-F248-11E8-B48F-1D18A9856A87
  last_name: Grasse
- first_name: Elisabeth
  full_name: Naderlinger, Elisabeth
  id: 31757262-F248-11E8-B48F-1D18A9856A87
  last_name: Naderlinger
- first_name: Christian
  full_name: Hilbe, Christian
  id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
  last_name: Hilbe
  orcid: 0000-0001-5116-955X
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
citation:
  ama: Milutinovic B, Stock M, Grasse AV, Naderlinger E, Hilbe C, Cremer S. Social
    immunity modulates competition between coinfecting pathogens. 2020. doi:<a href="https://doi.org/10.5061/DRYAD.CRJDFN318">10.5061/DRYAD.CRJDFN318</a>
  apa: Milutinovic, B., Stock, M., Grasse, A. V., Naderlinger, E., Hilbe, C., &#38;
    Cremer, S. (2020). Social immunity modulates competition between coinfecting pathogens.
    Dryad. <a href="https://doi.org/10.5061/DRYAD.CRJDFN318">https://doi.org/10.5061/DRYAD.CRJDFN318</a>
  chicago: Milutinovic, Barbara, Miriam Stock, Anna V Grasse, Elisabeth Naderlinger,
    Christian Hilbe, and Sylvia Cremer. “Social Immunity Modulates Competition between
    Coinfecting Pathogens.” Dryad, 2020. <a href="https://doi.org/10.5061/DRYAD.CRJDFN318">https://doi.org/10.5061/DRYAD.CRJDFN318</a>.
  ieee: B. Milutinovic, M. Stock, A. V. Grasse, E. Naderlinger, C. Hilbe, and S. Cremer,
    “Social immunity modulates competition between coinfecting pathogens.” Dryad,
    2020.
  ista: Milutinovic B, Stock M, Grasse AV, Naderlinger E, Hilbe C, Cremer S. 2020.
    Social immunity modulates competition between coinfecting pathogens, Dryad, <a
    href="https://doi.org/10.5061/DRYAD.CRJDFN318">10.5061/DRYAD.CRJDFN318</a>.
  mla: Milutinovic, Barbara, et al. <i>Social Immunity Modulates Competition between
    Coinfecting Pathogens</i>. Dryad, 2020, doi:<a href="https://doi.org/10.5061/DRYAD.CRJDFN318">10.5061/DRYAD.CRJDFN318</a>.
  short: B. Milutinovic, M. Stock, A.V. Grasse, E. Naderlinger, C. Hilbe, S. Cremer,
    (2020).
date_created: 2023-05-23T16:11:22Z
date_published: 2020-12-19T00:00:00Z
date_updated: 2023-09-05T16:04:48Z
day: '19'
ddc:
- '570'
department:
- _id: SyCr
- _id: KrCh
doi: 10.5061/DRYAD.CRJDFN318
license: https://creativecommons.org/publicdomain/zero/1.0/
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.crjdfn318
month: '12'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '7343'
    relation: used_in_publication
    status: public
status: public
title: Social immunity modulates competition between coinfecting pathogens
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '13065'
abstract:
- lang: eng
  text: Domestication is a human-induced selection process that imprints the genomes
    of domesticated populations over a short evolutionary time scale, and that occurs
    in a given demographic context. Reconstructing historical gene flow, effective
    population size changes and their timing is therefore of fundamental interest
    to understand how plant demography and human selection jointly shape genomic divergence
    during domestication. Yet, the comparison under a single statistical framework
    of independent domestication histories across different crop species has been
    little evaluated so far. Thus, it is unclear whether domestication leads to convergent
    demographic changes that similarly affect crop genomes. To address this question,
    we used existing and new transcriptome data on three crop species of Solanaceae
    (eggplant, pepper and tomato), together with their close wild relatives. We fitted
    twelve demographic models of increasing complexity on the unfolded joint allele
    frequency spectrum for each wild/crop pair, and we found evidence for both shared
    and species-specific demographic processes between species. A convergent history
    of domestication with gene-flow was inferred for all three species, along with
    evidence of strong reduction in the effective population size during the cultivation
    stage of tomato and pepper. The absence of any reduction in size of the crop in
    eggplant stands out from the classical view of the domestication process; as does
    the existence of a “protracted period” of management before cultivation. Our results
    also suggest divergent management strategies of modern cultivars among species
    as their current demography substantially differs. Finally, the timing of domestication
    is species-specific and supported by the few historical records available.
article_processing_charge: No
author:
- first_name: Stephanie
  full_name: Arnoux, Stephanie
  last_name: Arnoux
- first_name: Christelle
  full_name: Fraisse, Christelle
  id: 32DF5794-F248-11E8-B48F-1D18A9856A87
  last_name: Fraisse
  orcid: 0000-0001-8441-5075
- first_name: Christopher
  full_name: Sauvage, Christopher
  last_name: Sauvage
citation:
  ama: 'Arnoux S, Fraisse C, Sauvage C. VCF files of synonymous SNPs related to: Genomic
    inference of complex domestication histories in three Solanaceae species. 2020.
    doi:<a href="https://doi.org/10.5061/DRYAD.Q2BVQ83HD">10.5061/DRYAD.Q2BVQ83HD</a>'
  apa: 'Arnoux, S., Fraisse, C., &#38; Sauvage, C. (2020). VCF files of synonymous
    SNPs related to: Genomic inference of complex domestication histories in three
    Solanaceae species. Dryad. <a href="https://doi.org/10.5061/DRYAD.Q2BVQ83HD">https://doi.org/10.5061/DRYAD.Q2BVQ83HD</a>'
  chicago: 'Arnoux, Stephanie, Christelle Fraisse, and Christopher Sauvage. “VCF Files
    of Synonymous SNPs Related to: Genomic Inference of Complex Domestication Histories
    in Three Solanaceae Species.” Dryad, 2020. <a href="https://doi.org/10.5061/DRYAD.Q2BVQ83HD">https://doi.org/10.5061/DRYAD.Q2BVQ83HD</a>.'
  ieee: 'S. Arnoux, C. Fraisse, and C. Sauvage, “VCF files of synonymous SNPs related
    to: Genomic inference of complex domestication histories in three Solanaceae species.”
    Dryad, 2020.'
  ista: 'Arnoux S, Fraisse C, Sauvage C. 2020. VCF files of synonymous SNPs related
    to: Genomic inference of complex domestication histories in three Solanaceae species,
    Dryad, <a href="https://doi.org/10.5061/DRYAD.Q2BVQ83HD">10.5061/DRYAD.Q2BVQ83HD</a>.'
  mla: 'Arnoux, Stephanie, et al. <i>VCF Files of Synonymous SNPs Related to: Genomic
    Inference of Complex Domestication Histories in Three Solanaceae Species</i>.
    Dryad, 2020, doi:<a href="https://doi.org/10.5061/DRYAD.Q2BVQ83HD">10.5061/DRYAD.Q2BVQ83HD</a>.'
  short: S. Arnoux, C. Fraisse, C. Sauvage, (2020).
date_created: 2023-05-23T16:30:20Z
date_published: 2020-10-19T00:00:00Z
date_updated: 2023-08-04T11:19:26Z
day: '19'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.5061/DRYAD.Q2BVQ83HD
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.q2bvq83hd
month: '10'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  link:
  - relation: software
    url: https://github.com/starnoux/arnoux_et_al_2019
  record:
  - id: '8928'
    relation: used_in_publication
    status: public
status: public
title: 'VCF files of synonymous SNPs related to: Genomic inference of complex domestication
  histories in three Solanaceae species'
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '13070'
abstract:
- lang: eng
  text: This dataset comprises all data shown in the figures of the submitted article
    "Surpassing the resistance quantum with a geometric superinductor". Additional
    raw data are available from the corresponding author on reasonable request.
article_processing_charge: No
author:
- first_name: Matilda
  full_name: Peruzzo, Matilda
  id: 3F920B30-F248-11E8-B48F-1D18A9856A87
  last_name: Peruzzo
  orcid: 0000-0002-3415-4628
- first_name: Andrea
  full_name: Trioni, Andrea
  id: 42F71B44-F248-11E8-B48F-1D18A9856A87
  last_name: Trioni
- first_name: Farid
  full_name: Hassani, Farid
  id: 2AED110C-F248-11E8-B48F-1D18A9856A87
  last_name: Hassani
  orcid: 0000-0001-6937-5773
- first_name: Martin
  full_name: Zemlicka, Martin
  id: 2DCF8DE6-F248-11E8-B48F-1D18A9856A87
  last_name: Zemlicka
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
citation:
  ama: Peruzzo M, Trioni A, Hassani F, Zemlicka M, Fink JM. Surpassing the resistance
    quantum with a geometric superinductor. 2020. doi:<a href="https://doi.org/10.5281/ZENODO.4052882">10.5281/ZENODO.4052882</a>
  apa: Peruzzo, M., Trioni, A., Hassani, F., Zemlicka, M., &#38; Fink, J. M. (2020).
    Surpassing the resistance quantum with a geometric superinductor. Zenodo. <a href="https://doi.org/10.5281/ZENODO.4052882">https://doi.org/10.5281/ZENODO.4052882</a>
  chicago: Peruzzo, Matilda, Andrea Trioni, Farid Hassani, Martin Zemlicka, and Johannes
    M Fink. “Surpassing the Resistance Quantum with a Geometric Superinductor.” Zenodo,
    2020. <a href="https://doi.org/10.5281/ZENODO.4052882">https://doi.org/10.5281/ZENODO.4052882</a>.
  ieee: M. Peruzzo, A. Trioni, F. Hassani, M. Zemlicka, and J. M. Fink, “Surpassing
    the resistance quantum with a geometric superinductor.” Zenodo, 2020.
  ista: Peruzzo M, Trioni A, Hassani F, Zemlicka M, Fink JM. 2020. Surpassing the
    resistance quantum with a geometric superinductor, Zenodo, <a href="https://doi.org/10.5281/ZENODO.4052882">10.5281/ZENODO.4052882</a>.
  mla: Peruzzo, Matilda, et al. <i>Surpassing the Resistance Quantum with a Geometric
    Superinductor</i>. Zenodo, 2020, doi:<a href="https://doi.org/10.5281/ZENODO.4052882">10.5281/ZENODO.4052882</a>.
  short: M. Peruzzo, A. Trioni, F. Hassani, M. Zemlicka, J.M. Fink, (2020).
date_created: 2023-05-23T16:42:30Z
date_published: 2020-09-27T00:00:00Z
date_updated: 2024-09-10T12:23:56Z
day: '27'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.5281/ZENODO.4052882
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5281/zenodo.4052883
month: '09'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
  record:
  - id: '8755'
    relation: used_in_publication
    status: public
status: public
title: Surpassing the resistance quantum with a geometric superinductor
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '13071'
abstract:
- lang: eng
  text: This dataset comprises all data shown in the plots of the main part of the
    submitted article "Bidirectional Electro-Optic Wavelength Conversion in the Quantum
    Ground State". Additional raw data are available from the corresponding author
    on reasonable request.
article_processing_charge: No
author:
- first_name: William J
  full_name: Hease, William J
  id: 29705398-F248-11E8-B48F-1D18A9856A87
  last_name: Hease
  orcid: 0000-0001-9868-2166
- first_name: Alfredo R
  full_name: Rueda Sanchez, Alfredo R
  id: 3B82B0F8-F248-11E8-B48F-1D18A9856A87
  last_name: Rueda Sanchez
  orcid: 0000-0001-6249-5860
- first_name: Rishabh
  full_name: Sahu, Rishabh
  id: 47D26E34-F248-11E8-B48F-1D18A9856A87
  last_name: Sahu
  orcid: 0000-0001-6264-2162
- first_name: Matthias
  full_name: Wulf, Matthias
  id: 45598606-F248-11E8-B48F-1D18A9856A87
  last_name: Wulf
  orcid: 0000-0001-6613-1378
- first_name: Georg M
  full_name: Arnold, Georg M
  id: 3770C838-F248-11E8-B48F-1D18A9856A87
  last_name: Arnold
  orcid: 0000-0003-1397-7876
- first_name: Harald
  full_name: Schwefel, Harald
  last_name: Schwefel
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
citation:
  ama: Hease WJ, Rueda Sanchez AR, Sahu R, et al. Bidirectional electro-optic wavelength
    conversion in the quantum ground state. 2020. doi:<a href="https://doi.org/10.5281/ZENODO.4266025">10.5281/ZENODO.4266025</a>
  apa: Hease, W. J., Rueda Sanchez, A. R., Sahu, R., Wulf, M., Arnold, G. M., Schwefel,
    H., &#38; Fink, J. M. (2020). Bidirectional electro-optic wavelength conversion
    in the quantum ground state. Zenodo. <a href="https://doi.org/10.5281/ZENODO.4266025">https://doi.org/10.5281/ZENODO.4266025</a>
  chicago: Hease, William J, Alfredo R Rueda Sanchez, Rishabh Sahu, Matthias Wulf,
    Georg M Arnold, Harald Schwefel, and Johannes M Fink. “Bidirectional Electro-Optic
    Wavelength Conversion in the Quantum Ground State.” Zenodo, 2020. <a href="https://doi.org/10.5281/ZENODO.4266025">https://doi.org/10.5281/ZENODO.4266025</a>.
  ieee: W. J. Hease <i>et al.</i>, “Bidirectional electro-optic wavelength conversion
    in the quantum ground state.” Zenodo, 2020.
  ista: Hease WJ, Rueda Sanchez AR, Sahu R, Wulf M, Arnold GM, Schwefel H, Fink JM.
    2020. Bidirectional electro-optic wavelength conversion in the quantum ground
    state, Zenodo, <a href="https://doi.org/10.5281/ZENODO.4266025">10.5281/ZENODO.4266025</a>.
  mla: Hease, William J., et al. <i>Bidirectional Electro-Optic Wavelength Conversion
    in the Quantum Ground State</i>. Zenodo, 2020, doi:<a href="https://doi.org/10.5281/ZENODO.4266025">10.5281/ZENODO.4266025</a>.
  short: W.J. Hease, A.R. Rueda Sanchez, R. Sahu, M. Wulf, G.M. Arnold, H. Schwefel,
    J.M. Fink, (2020).
date_created: 2023-05-23T16:44:11Z
date_published: 2020-11-10T00:00:00Z
date_updated: 2024-09-10T12:23:54Z
day: '10'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.5281/ZENODO.4266025
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5281/zenodo.4266026
month: '11'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
  record:
  - id: '9114'
    relation: used_in_publication
    status: public
status: public
title: Bidirectional electro-optic wavelength conversion in the quantum ground state
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '13073'
abstract:
- lang: eng
  text: The Mytilus complex of marine mussel species forms a mosaic of hybrid zones,
    found across temperate regions of the globe. This allows us to study "replicated"
    instances of secondary contact between closely-related species. Previous work
    on this complex has shown that local introgression is both widespread and highly
    heterogeneous, and has identified SNPs that are outliers of differentiation between
    lineages. Here, we developed an ancestry-informative panel of such SNPs. We then
    compared their frequencies in newly-sampled populations, including samples from
    within the hybrid zones, and parental populations at different distances from
    the contact. Results show that close to the hybrid zones, some outlier loci are
    near to fixation for the heterospecific allele, suggesting enhanced local introgression,
    or the local sweep of a shared ancestral allele. Conversely, genomic cline analyses,
    treating local parental populations as the reference, reveal a globally high concordance
    among loci, albeit with a few signals of asymmetric introgression. Enhanced local
    introgression at specific loci is consistent with the early transfer of adaptive
    variants after contact, possibly including asymmetric bi-stable variants (Dobzhansky-Muller
    incompatibilities), or haplotypes loaded with fewer deleterious mutations. Having
    escaped one barrier, however, these variants can be trapped or delayed at the
    next barrier, confining the introgression locally. These results shed light on
    the decay of species barriers during phases of contact.
article_processing_charge: No
author:
- first_name: Alexis
  full_name: Simon, Alexis
  last_name: Simon
- first_name: Christelle
  full_name: Fraisse, Christelle
  id: 32DF5794-F248-11E8-B48F-1D18A9856A87
  last_name: Fraisse
  orcid: 0000-0001-8441-5075
- first_name: Tahani
  full_name: El Ayari, Tahani
  last_name: El Ayari
- first_name: Cathy
  full_name: Liautard-Haag, Cathy
  last_name: Liautard-Haag
- first_name: Petr
  full_name: Strelkov, Petr
  last_name: Strelkov
- first_name: John
  full_name: Welch, John
  last_name: Welch
- first_name: Nicolas
  full_name: Bierne, Nicolas
  last_name: Bierne
citation:
  ama: Simon A, Fraisse C, El Ayari T, et al. How do species barriers decay? concordance
    and local introgression in mosaic hybrid zones of mussels. 2020. doi:<a href="https://doi.org/10.5061/DRYAD.R4XGXD29N">10.5061/DRYAD.R4XGXD29N</a>
  apa: Simon, A., Fraisse, C., El Ayari, T., Liautard-Haag, C., Strelkov, P., Welch,
    J., &#38; Bierne, N. (2020). How do species barriers decay? concordance and local
    introgression in mosaic hybrid zones of mussels. Dryad. <a href="https://doi.org/10.5061/DRYAD.R4XGXD29N">https://doi.org/10.5061/DRYAD.R4XGXD29N</a>
  chicago: Simon, Alexis, Christelle Fraisse, Tahani El Ayari, Cathy Liautard-Haag,
    Petr Strelkov, John Welch, and Nicolas Bierne. “How Do Species Barriers Decay?
    Concordance and Local Introgression in Mosaic Hybrid Zones of Mussels.” Dryad,
    2020. <a href="https://doi.org/10.5061/DRYAD.R4XGXD29N">https://doi.org/10.5061/DRYAD.R4XGXD29N</a>.
  ieee: A. Simon <i>et al.</i>, “How do species barriers decay? concordance and local
    introgression in mosaic hybrid zones of mussels.” Dryad, 2020.
  ista: Simon A, Fraisse C, El Ayari T, Liautard-Haag C, Strelkov P, Welch J, Bierne
    N. 2020. How do species barriers decay? concordance and local introgression in
    mosaic hybrid zones of mussels, Dryad, <a href="https://doi.org/10.5061/DRYAD.R4XGXD29N">10.5061/DRYAD.R4XGXD29N</a>.
  mla: Simon, Alexis, et al. <i>How Do Species Barriers Decay? Concordance and Local
    Introgression in Mosaic Hybrid Zones of Mussels</i>. Dryad, 2020, doi:<a href="https://doi.org/10.5061/DRYAD.R4XGXD29N">10.5061/DRYAD.R4XGXD29N</a>.
  short: A. Simon, C. Fraisse, T. El Ayari, C. Liautard-Haag, P. Strelkov, J. Welch,
    N. Bierne, (2020).
date_created: 2023-05-23T16:48:27Z
date_published: 2020-09-22T00:00:00Z
date_updated: 2023-08-04T11:04:11Z
day: '22'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.5061/DRYAD.R4XGXD29N
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.r4xgxd29n
month: '09'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '8708'
    relation: used_in_publication
    status: public
status: public
title: How do species barriers decay? concordance and local introgression in mosaic
  hybrid zones of mussels
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '14125'
abstract:
- lang: eng
  text: "Motivation: Recent technological advances have led to an increase in the
    production and availability of single-cell data. The ability to integrate a set
    of multi-technology measurements would allow the identification of biologically
    or clinically meaningful observations through the unification of the perspectives
    afforded by each technology. In most cases, however, profiling technologies consume
    the used cells and thus pairwise correspondences between datasets are lost. Due
    to the sheer size single-cell datasets can acquire, scalable algorithms that are
    able to universally match single-cell measurements carried out in one cell to
    its corresponding sibling in another technology are needed.\r\nResults: We propose
    Single-Cell data Integration via Matching (SCIM), a scalable approach to recover
    such correspondences in two or more technologies. SCIM assumes that cells share
    a common (low-dimensional) underlying structure and that the underlying cell distribution
    is approximately constant across technologies. It constructs a technology-invariant
    latent space using an autoencoder framework with an adversarial objective. Multi-modal
    datasets are integrated by pairing cells across technologies using a bipartite
    matching scheme that operates on the low-dimensional latent representations. We
    evaluate SCIM on a simulated cellular branching process and show that the cell-to-cell
    matches derived by SCIM reflect the same pseudotime on the simulated dataset.
    Moreover, we apply our method to two real-world scenarios, a melanoma tumor sample
    and a human bone marrow sample, where we pair cells from a scRNA dataset to their
    sibling cells in a CyTOF dataset achieving 90% and 78% cell-matching accuracy
    for each one of the samples, respectively."
article_processing_charge: No
article_type: original
author:
- first_name: Stefan G
  full_name: Stark, Stefan G
  last_name: Stark
- first_name: Joanna
  full_name: Ficek, Joanna
  last_name: Ficek
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
- first_name: Ximena
  full_name: Bonilla, Ximena
  last_name: Bonilla
- first_name: Stéphane
  full_name: Chevrier, Stéphane
  last_name: Chevrier
- first_name: Franziska
  full_name: Singer, Franziska
  last_name: Singer
- first_name: Rudolf
  full_name: Aebersold, Rudolf
  last_name: Aebersold
- first_name: Faisal S
  full_name: Al-Quaddoomi, Faisal S
  last_name: Al-Quaddoomi
- first_name: Jonas
  full_name: Albinus, Jonas
  last_name: Albinus
- first_name: Ilaria
  full_name: Alborelli, Ilaria
  last_name: Alborelli
- first_name: Sonali
  full_name: Andani, Sonali
  last_name: Andani
- first_name: Per-Olof
  full_name: Attinger, Per-Olof
  last_name: Attinger
- first_name: Marina
  full_name: Bacac, Marina
  last_name: Bacac
- first_name: Daniel
  full_name: Baumhoer, Daniel
  last_name: Baumhoer
- first_name: Beatrice
  full_name: Beck-Schimmer, Beatrice
  last_name: Beck-Schimmer
- first_name: Niko
  full_name: Beerenwinkel, Niko
  last_name: Beerenwinkel
- first_name: Christian
  full_name: Beisel, Christian
  last_name: Beisel
- first_name: Lara
  full_name: Bernasconi, Lara
  last_name: Bernasconi
- first_name: Anne
  full_name: Bertolini, Anne
  last_name: Bertolini
- first_name: Bernd
  full_name: Bodenmiller, Bernd
  last_name: Bodenmiller
- first_name: Ximena
  full_name: Bonilla, Ximena
  last_name: Bonilla
- first_name: Ruben
  full_name: Casanova, Ruben
  last_name: Casanova
- first_name: Stéphane
  full_name: Chevrier, Stéphane
  last_name: Chevrier
- first_name: Natalia
  full_name: Chicherova, Natalia
  last_name: Chicherova
- first_name: Maya
  full_name: D'Costa, Maya
  last_name: D'Costa
- first_name: Esther
  full_name: Danenberg, Esther
  last_name: Danenberg
- first_name: Natalie
  full_name: Davidson, Natalie
  last_name: Davidson
- first_name: Monica-Andreea Dră
  full_name: gan, Monica-Andreea Dră
  last_name: gan
- first_name: Reinhard
  full_name: Dummer, Reinhard
  last_name: Dummer
- first_name: Stefanie
  full_name: Engler, Stefanie
  last_name: Engler
- first_name: Martin
  full_name: Erkens, Martin
  last_name: Erkens
- first_name: Katja
  full_name: Eschbach, Katja
  last_name: Eschbach
- first_name: Cinzia
  full_name: Esposito, Cinzia
  last_name: Esposito
- first_name: André
  full_name: Fedier, André
  last_name: Fedier
- first_name: Pedro
  full_name: Ferreira, Pedro
  last_name: Ferreira
- first_name: Joanna
  full_name: Ficek, Joanna
  last_name: Ficek
- first_name: Anja L
  full_name: Frei, Anja L
  last_name: Frei
- first_name: Bruno
  full_name: Frey, Bruno
  last_name: Frey
- first_name: Sandra
  full_name: Goetze, Sandra
  last_name: Goetze
- first_name: Linda
  full_name: Grob, Linda
  last_name: Grob
- first_name: Gabriele
  full_name: Gut, Gabriele
  last_name: Gut
- first_name: Detlef
  full_name: Günther, Detlef
  last_name: Günther
- first_name: Martina
  full_name: Haberecker, Martina
  last_name: Haberecker
- first_name: Pirmin
  full_name: Haeuptle, Pirmin
  last_name: Haeuptle
- first_name: Viola
  full_name: Heinzelmann-Schwarz, Viola
  last_name: Heinzelmann-Schwarz
- first_name: Sylvia
  full_name: Herter, Sylvia
  last_name: Herter
- first_name: Rene
  full_name: Holtackers, Rene
  last_name: Holtackers
- first_name: Tamara
  full_name: Huesser, Tamara
  last_name: Huesser
- first_name: Anja
  full_name: Irmisch, Anja
  last_name: Irmisch
- first_name: Francis
  full_name: Jacob, Francis
  last_name: Jacob
- first_name: Andrea
  full_name: Jacobs, Andrea
  last_name: Jacobs
- first_name: Tim M
  full_name: Jaeger, Tim M
  last_name: Jaeger
- first_name: Katharina
  full_name: Jahn, Katharina
  last_name: Jahn
- first_name: Alva R
  full_name: James, Alva R
  last_name: James
- first_name: Philip M
  full_name: Jermann, Philip M
  last_name: Jermann
- first_name: André
  full_name: Kahles, André
  last_name: Kahles
- first_name: Abdullah
  full_name: Kahraman, Abdullah
  last_name: Kahraman
- first_name: Viktor H
  full_name: Koelzer, Viktor H
  last_name: Koelzer
- first_name: Werner
  full_name: Kuebler, Werner
  last_name: Kuebler
- first_name: Jack
  full_name: Kuipers, Jack
  last_name: Kuipers
- first_name: Christian P
  full_name: Kunze, Christian P
  last_name: Kunze
- first_name: Christian
  full_name: Kurzeder, Christian
  last_name: Kurzeder
- first_name: Kjong-Van
  full_name: Lehmann, Kjong-Van
  last_name: Lehmann
- first_name: Mitchell
  full_name: Levesque, Mitchell
  last_name: Levesque
- first_name: Sebastian
  full_name: Lugert, Sebastian
  last_name: Lugert
- first_name: Gerd
  full_name: Maass, Gerd
  last_name: Maass
- first_name: Markus
  full_name: Manz, Markus
  last_name: Manz
- first_name: Philipp
  full_name: Markolin, Philipp
  last_name: Markolin
- first_name: Julien
  full_name: Mena, Julien
  last_name: Mena
- first_name: Ulrike
  full_name: Menzel, Ulrike
  last_name: Menzel
- first_name: Julian M
  full_name: Metzler, Julian M
  last_name: Metzler
- first_name: Nicola
  full_name: Miglino, Nicola
  last_name: Miglino
- first_name: Emanuela S
  full_name: Milani, Emanuela S
  last_name: Milani
- first_name: Holger
  full_name: Moch, Holger
  last_name: Moch
- first_name: Simone
  full_name: Muenst, Simone
  last_name: Muenst
- first_name: Riccardo
  full_name: Murri, Riccardo
  last_name: Murri
- first_name: Charlotte KY
  full_name: Ng, Charlotte KY
  last_name: Ng
- first_name: Stefan
  full_name: Nicolet, Stefan
  last_name: Nicolet
- first_name: Marta
  full_name: Nowak, Marta
  last_name: Nowak
- first_name: Patrick GA
  full_name: Pedrioli, Patrick GA
  last_name: Pedrioli
- first_name: Lucas
  full_name: Pelkmans, Lucas
  last_name: Pelkmans
- first_name: Salvatore
  full_name: Piscuoglio, Salvatore
  last_name: Piscuoglio
- first_name: Michael
  full_name: Prummer, Michael
  last_name: Prummer
- first_name: Mathilde
  full_name: Ritter, Mathilde
  last_name: Ritter
- first_name: Christian
  full_name: Rommel, Christian
  last_name: Rommel
- first_name: María L
  full_name: Rosano-González, María L
  last_name: Rosano-González
- first_name: Gunnar
  full_name: Rätsch, Gunnar
  last_name: Rätsch
- first_name: Natascha
  full_name: Santacroce, Natascha
  last_name: Santacroce
- first_name: Jacobo Sarabia del
  full_name: Castillo, Jacobo Sarabia del
  last_name: Castillo
- first_name: Ramona
  full_name: Schlenker, Ramona
  last_name: Schlenker
- first_name: Petra C
  full_name: Schwalie, Petra C
  last_name: Schwalie
- first_name: Severin
  full_name: Schwan, Severin
  last_name: Schwan
- first_name: Tobias
  full_name: Schär, Tobias
  last_name: Schär
- first_name: Gabriela
  full_name: Senti, Gabriela
  last_name: Senti
- first_name: Franziska
  full_name: Singer, Franziska
  last_name: Singer
- first_name: Sujana
  full_name: Sivapatham, Sujana
  last_name: Sivapatham
- first_name: Berend
  full_name: Snijder, Berend
  last_name: Snijder
- first_name: Bettina
  full_name: Sobottka, Bettina
  last_name: Sobottka
- first_name: Vipin T
  full_name: Sreedharan, Vipin T
  last_name: Sreedharan
- first_name: Stefan
  full_name: Stark, Stefan
  last_name: Stark
- first_name: Daniel J
  full_name: Stekhoven, Daniel J
  last_name: Stekhoven
- first_name: Alexandre PA
  full_name: Theocharides, Alexandre PA
  last_name: Theocharides
- first_name: Tinu M
  full_name: Thomas, Tinu M
  last_name: Thomas
- first_name: Markus
  full_name: Tolnay, Markus
  last_name: Tolnay
- first_name: Vinko
  full_name: Tosevski, Vinko
  last_name: Tosevski
- first_name: Nora C
  full_name: Toussaint, Nora C
  last_name: Toussaint
- first_name: Mustafa A
  full_name: Tuncel, Mustafa A
  last_name: Tuncel
- first_name: Marina
  full_name: Tusup, Marina
  last_name: Tusup
- first_name: Audrey Van
  full_name: Drogen, Audrey Van
  last_name: Drogen
- first_name: Marcus
  full_name: Vetter, Marcus
  last_name: Vetter
- first_name: Tatjana
  full_name: Vlajnic, Tatjana
  last_name: Vlajnic
- first_name: Sandra
  full_name: Weber, Sandra
  last_name: Weber
- first_name: Walter P
  full_name: Weber, Walter P
  last_name: Weber
- first_name: Rebekka
  full_name: Wegmann, Rebekka
  last_name: Wegmann
- first_name: Michael
  full_name: Weller, Michael
  last_name: Weller
- first_name: Fabian
  full_name: Wendt, Fabian
  last_name: Wendt
- first_name: Norbert
  full_name: Wey, Norbert
  last_name: Wey
- first_name: Andreas
  full_name: Wicki, Andreas
  last_name: Wicki
- first_name: Bernd
  full_name: Wollscheid, Bernd
  last_name: Wollscheid
- first_name: Shuqing
  full_name: Yu, Shuqing
  last_name: Yu
- first_name: Johanna
  full_name: Ziegler, Johanna
  last_name: Ziegler
- first_name: Marc
  full_name: Zimmermann, Marc
  last_name: Zimmermann
- first_name: Martin
  full_name: Zoche, Martin
  last_name: Zoche
- first_name: Gregor
  full_name: Zuend, Gregor
  last_name: Zuend
- first_name: Gunnar
  full_name: Rätsch, Gunnar
  last_name: Rätsch
- first_name: Kjong-Van
  full_name: Lehmann, Kjong-Van
  last_name: Lehmann
citation:
  ama: 'Stark SG, Ficek J, Locatello F, et al. SCIM: Universal single-cell matching
    with unpaired feature sets. <i>Bioinformatics</i>. 2020;36(Supplement_2):i919-i927.
    doi:<a href="https://doi.org/10.1093/bioinformatics/btaa843">10.1093/bioinformatics/btaa843</a>'
  apa: 'Stark, S. G., Ficek, J., Locatello, F., Bonilla, X., Chevrier, S., Singer,
    F., … Lehmann, K.-V. (2020). SCIM: Universal single-cell matching with unpaired
    feature sets. <i>Bioinformatics</i>. Oxford University Press. <a href="https://doi.org/10.1093/bioinformatics/btaa843">https://doi.org/10.1093/bioinformatics/btaa843</a>'
  chicago: 'Stark, Stefan G, Joanna Ficek, Francesco Locatello, Ximena Bonilla, Stéphane
    Chevrier, Franziska Singer, Rudolf Aebersold, et al. “SCIM: Universal Single-Cell
    Matching with Unpaired Feature Sets.” <i>Bioinformatics</i>. Oxford University
    Press, 2020. <a href="https://doi.org/10.1093/bioinformatics/btaa843">https://doi.org/10.1093/bioinformatics/btaa843</a>.'
  ieee: 'S. G. Stark <i>et al.</i>, “SCIM: Universal single-cell matching with unpaired
    feature sets,” <i>Bioinformatics</i>, vol. 36, no. Supplement_2. Oxford University
    Press, pp. i919–i927, 2020.'
  ista: 'Stark SG et al. 2020. SCIM: Universal single-cell matching with unpaired
    feature sets. Bioinformatics. 36(Supplement_2), i919–i927.'
  mla: 'Stark, Stefan G., et al. “SCIM: Universal Single-Cell Matching with Unpaired
    Feature Sets.” <i>Bioinformatics</i>, vol. 36, no. Supplement_2, Oxford University
    Press, 2020, pp. i919–27, doi:<a href="https://doi.org/10.1093/bioinformatics/btaa843">10.1093/bioinformatics/btaa843</a>.'
  short: S.G. Stark, J. Ficek, F. Locatello, X. Bonilla, S. Chevrier, F. Singer, R.
    Aebersold, F.S. Al-Quaddoomi, J. Albinus, I. Alborelli, S. Andani, P.-O. Attinger,
    M. Bacac, D. Baumhoer, B. Beck-Schimmer, N. Beerenwinkel, C. Beisel, L. Bernasconi,
    A. Bertolini, B. Bodenmiller, X. Bonilla, R. Casanova, S. Chevrier, N. Chicherova,
    M. D’Costa, E. Danenberg, N. Davidson, M.-A.D. gan, R. Dummer, S. Engler, M. Erkens,
    K. Eschbach, C. Esposito, A. Fedier, P. Ferreira, J. Ficek, A.L. Frei, B. Frey,
    S. Goetze, L. Grob, G. Gut, D. Günther, M. Haberecker, P. Haeuptle, V. Heinzelmann-Schwarz,
    S. Herter, R. Holtackers, T. Huesser, A. Irmisch, F. Jacob, A. Jacobs, T.M. Jaeger,
    K. Jahn, A.R. James, P.M. Jermann, A. Kahles, A. Kahraman, V.H. Koelzer, W. Kuebler,
    J. Kuipers, C.P. Kunze, C. Kurzeder, K.-V. Lehmann, M. Levesque, S. Lugert, G.
    Maass, M. Manz, P. Markolin, J. Mena, U. Menzel, J.M. Metzler, N. Miglino, E.S.
    Milani, H. Moch, S. Muenst, R. Murri, C.K. Ng, S. Nicolet, M. Nowak, P.G. Pedrioli,
    L. Pelkmans, S. Piscuoglio, M. Prummer, M. Ritter, C. Rommel, M.L. Rosano-González,
    G. Rätsch, N. Santacroce, J.S. del Castillo, R. Schlenker, P.C. Schwalie, S. Schwan,
    T. Schär, G. Senti, F. Singer, S. Sivapatham, B. Snijder, B. Sobottka, V.T. Sreedharan,
    S. Stark, D.J. Stekhoven, A.P. Theocharides, T.M. Thomas, M. Tolnay, V. Tosevski,
    N.C. Toussaint, M.A. Tuncel, M. Tusup, A.V. Drogen, M. Vetter, T. Vlajnic, S.
    Weber, W.P. Weber, R. Wegmann, M. Weller, F. Wendt, N. Wey, A. Wicki, B. Wollscheid,
    S. Yu, J. Ziegler, M. Zimmermann, M. Zoche, G. Zuend, G. Rätsch, K.-V. Lehmann,
    Bioinformatics 36 (2020) i919–i927.
date_created: 2023-08-21T12:28:20Z
date_published: 2020-12-01T00:00:00Z
date_updated: 2023-09-11T10:21:00Z
day: '01'
department:
- _id: FrLo
doi: 10.1093/bioinformatics/btaa843
extern: '1'
external_id:
  pmid:
  - '33381818'
intvolume: '        36'
issue: Supplement_2
keyword:
- Computational Mathematics
- Computational Theory and Mathematics
- Computer Science Applications
- Molecular Biology
- Biochemistry
- Statistics and Probability
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1093/bioinformatics/btaa843
month: '12'
oa: 1
oa_version: Published Version
page: i919-i927
pmid: 1
publication: Bioinformatics
publication_identifier:
  eissn:
  - 1367-4811
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/ratschlab/scim
scopus_import: '1'
status: public
title: 'SCIM: Universal single-cell matching with unpaired feature sets'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2020'
...
---
_id: '14186'
abstract:
- lang: eng
  text: "The goal of the unsupervised learning of disentangled representations is
    to\r\nseparate the independent explanatory factors of variation in the data without\r\naccess
    to supervision. In this paper, we summarize the results of Locatello et\r\nal.,
    2019, and focus on their implications for practitioners. We discuss the\r\ntheoretical
    result showing that the unsupervised learning of disentangled\r\nrepresentations
    is fundamentally impossible without inductive biases and the\r\npractical challenges
    it entails. Finally, we comment on our experimental\r\nfindings, highlighting
    the limitations of state-of-the-art approaches and\r\ndirections for future research."
article_processing_charge: No
arxiv: 1
author:
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
- first_name: Stefan
  full_name: Bauer, Stefan
  last_name: Bauer
- first_name: Mario
  full_name: Lucic, Mario
  last_name: Lucic
- first_name: Gunnar
  full_name: Rätsch, Gunnar
  last_name: Rätsch
- first_name: Sylvain
  full_name: Gelly, Sylvain
  last_name: Gelly
- first_name: Bernhard
  full_name: Schölkopf, Bernhard
  last_name: Schölkopf
- first_name: Olivier
  full_name: Bachem, Olivier
  last_name: Bachem
citation:
  ama: 'Locatello F, Bauer S, Lucic M, et al. A commentary on the unsupervised learning
    of disentangled representations. In: <i>The 34th AAAI Conference on Artificial
    Intelligence</i>. Vol 34. Association for the Advancement of Artificial Intelligence;
    2020:13681-13684. doi:<a href="https://doi.org/10.1609/aaai.v34i09.7120">10.1609/aaai.v34i09.7120</a>'
  apa: 'Locatello, F., Bauer, S., Lucic, M., Rätsch, G., Gelly, S., Schölkopf, B.,
    &#38; Bachem, O. (2020). A commentary on the unsupervised learning of disentangled
    representations. In <i>The 34th AAAI Conference on Artificial Intelligence</i>
    (Vol. 34, pp. 13681–13684). New York, NY, United States: Association for the Advancement
    of Artificial Intelligence. <a href="https://doi.org/10.1609/aaai.v34i09.7120">https://doi.org/10.1609/aaai.v34i09.7120</a>'
  chicago: Locatello, Francesco, Stefan Bauer, Mario Lucic, Gunnar Rätsch, Sylvain
    Gelly, Bernhard Schölkopf, and Olivier Bachem. “A Commentary on the Unsupervised
    Learning of Disentangled Representations.” In <i>The 34th AAAI Conference on Artificial
    Intelligence</i>, 34:13681–84. Association for the Advancement of Artificial Intelligence,
    2020. <a href="https://doi.org/10.1609/aaai.v34i09.7120">https://doi.org/10.1609/aaai.v34i09.7120</a>.
  ieee: F. Locatello <i>et al.</i>, “A commentary on the unsupervised learning of
    disentangled representations,” in <i>The 34th AAAI Conference on Artificial Intelligence</i>,
    New York, NY, United States, 2020, vol. 34, no. 9, pp. 13681–13684.
  ista: 'Locatello F, Bauer S, Lucic M, Rätsch G, Gelly S, Schölkopf B, Bachem O.
    2020. A commentary on the unsupervised learning of disentangled representations.
    The 34th AAAI Conference on Artificial Intelligence. AAAI: Conference on Artificial
    Intelligence vol. 34, 13681–13684.'
  mla: Locatello, Francesco, et al. “A Commentary on the Unsupervised Learning of
    Disentangled Representations.” <i>The 34th AAAI Conference on Artificial Intelligence</i>,
    vol. 34, no. 9, Association for the Advancement of Artificial Intelligence, 2020,
    pp. 13681–84, doi:<a href="https://doi.org/10.1609/aaai.v34i09.7120">10.1609/aaai.v34i09.7120</a>.
  short: F. Locatello, S. Bauer, M. Lucic, G. Rätsch, S. Gelly, B. Schölkopf, O. Bachem,
    in:, The 34th AAAI Conference on Artificial Intelligence, Association for the
    Advancement of Artificial Intelligence, 2020, pp. 13681–13684.
conference:
  end_date: 2020-02-12
  location: New York, NY, United States
  name: 'AAAI: Conference on Artificial Intelligence'
  start_date: 2020-02-07
date_created: 2023-08-22T14:07:26Z
date_published: 2020-07-28T00:00:00Z
date_updated: 2023-09-12T07:44:48Z
day: '28'
department:
- _id: FrLo
doi: 10.1609/aaai.v34i09.7120
extern: '1'
external_id:
  arxiv:
  - '2007.14184'
intvolume: '        34'
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2007.14184
month: '07'
oa: 1
oa_version: Preprint
page: 13681-13684
publication: The 34th AAAI Conference on Artificial Intelligence
publication_identifier:
  eissn:
  - 2374-3468
  isbn:
  - '9781577358350'
publication_status: published
publisher: Association for the Advancement of Artificial Intelligence
quality_controlled: '1'
scopus_import: '1'
status: public
title: A commentary on the unsupervised learning of disentangled representations
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2020'
...
---
_id: '14187'
abstract:
- lang: eng
  text: "We propose a novel Stochastic Frank-Wolfe (a.k.a. conditional gradient)\r\nalgorithm
    for constrained smooth finite-sum minimization with a generalized\r\nlinear prediction/structure.
    This class of problems includes empirical risk\r\nminimization with sparse, low-rank,
    or other structured constraints. The\r\nproposed method is simple to implement,
    does not require step-size tuning, and\r\nhas a constant per-iteration cost that
    is independent of the dataset size.\r\nFurthermore, as a byproduct of the method
    we obtain a stochastic estimator of\r\nthe Frank-Wolfe gap that can be used as
    a stopping criterion. Depending on the\r\nsetting, the proposed method matches
    or improves on the best computational\r\nguarantees for Stochastic Frank-Wolfe
    algorithms. Benchmarks on several\r\ndatasets highlight different regimes in which
    the proposed method exhibits a\r\nfaster empirical convergence than related methods.
    Finally, we provide an\r\nimplementation of all considered methods in an open-source
    package."
alternative_title:
- PMLR
article_processing_charge: No
arxiv: 1
author:
- first_name: Geoffrey
  full_name: Négiar, Geoffrey
  last_name: Négiar
- first_name: Gideon
  full_name: Dresdner, Gideon
  last_name: Dresdner
- first_name: Alicia
  full_name: Tsai, Alicia
  last_name: Tsai
- first_name: Laurent El
  full_name: Ghaoui, Laurent El
  last_name: Ghaoui
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
- first_name: Robert M.
  full_name: Freund, Robert M.
  last_name: Freund
- first_name: Fabian
  full_name: Pedregosa, Fabian
  last_name: Pedregosa
citation:
  ama: 'Négiar G, Dresdner G, Tsai A, et al. Stochastic Frank-Wolfe for constrained
    finite-sum minimization. In: <i>Proceedings of the 37th International Conference
    on Machine Learning</i>. Vol 119. ; 2020:7253-7262.'
  apa: Négiar, G., Dresdner, G., Tsai, A., Ghaoui, L. E., Locatello, F., Freund, R.
    M., &#38; Pedregosa, F. (2020). Stochastic Frank-Wolfe for constrained finite-sum
    minimization. In <i>Proceedings of the 37th International Conference on Machine
    Learning</i> (Vol. 119, pp. 7253–7262). Virtual.
  chicago: Négiar, Geoffrey, Gideon Dresdner, Alicia Tsai, Laurent El Ghaoui, Francesco
    Locatello, Robert M. Freund, and Fabian Pedregosa. “Stochastic Frank-Wolfe for
    Constrained Finite-Sum Minimization.” In <i>Proceedings of the 37th International
    Conference on Machine Learning</i>, 119:7253–62, 2020.
  ieee: G. Négiar <i>et al.</i>, “Stochastic Frank-Wolfe for constrained finite-sum
    minimization,” in <i>Proceedings of the 37th International Conference on Machine
    Learning</i>, Virtual, 2020, vol. 119, pp. 7253–7262.
  ista: Négiar G, Dresdner G, Tsai A, Ghaoui LE, Locatello F, Freund RM, Pedregosa
    F. 2020. Stochastic Frank-Wolfe for constrained finite-sum minimization. Proceedings
    of the 37th International Conference on Machine Learning. International Conference
    on Machine Learning, PMLR, vol. 119, 7253–7262.
  mla: Négiar, Geoffrey, et al. “Stochastic Frank-Wolfe for Constrained Finite-Sum
    Minimization.” <i>Proceedings of the 37th International Conference on Machine
    Learning</i>, vol. 119, 2020, pp. 7253–62.
  short: G. Négiar, G. Dresdner, A. Tsai, L.E. Ghaoui, F. Locatello, R.M. Freund,
    F. Pedregosa, in:, Proceedings of the 37th International Conference on Machine
    Learning, 2020, pp. 7253–7262.
conference:
  end_date: 2020-07-18
  location: Virtual
  name: International Conference on Machine Learning
  start_date: 2020-07-13
date_created: 2023-08-22T14:07:52Z
date_published: 2020-07-27T00:00:00Z
date_updated: 2023-09-12T08:03:40Z
day: '27'
department:
- _id: FrLo
extern: '1'
external_id:
  arxiv:
  - '2002.11860'
intvolume: '       119'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2002.11860
month: '07'
oa: 1
oa_version: Preprint
page: 7253-7262
publication: Proceedings of the 37th International Conference on Machine Learning
publication_status: published
quality_controlled: '1'
status: public
title: Stochastic Frank-Wolfe for constrained finite-sum minimization
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 119
year: '2020'
...
---
_id: '14188'
abstract:
- lang: eng
  text: "Intelligent agents should be able to learn useful representations by\r\nobserving
    changes in their environment. We model such observations as pairs of\r\nnon-i.i.d.
    images sharing at least one of the underlying factors of variation.\r\nFirst,
    we theoretically show that only knowing how many factors have changed,\r\nbut
    not which ones, is sufficient to learn disentangled representations.\r\nSecond,
    we provide practical algorithms that learn disentangled representations\r\nfrom
    pairs of images without requiring annotation of groups, individual\r\nfactors,
    or the number of factors that have changed. Third, we perform a\r\nlarge-scale
    empirical study and show that such pairs of observations are\r\nsufficient to
    reliably learn disentangled representations on several benchmark\r\ndata sets.
    Finally, we evaluate our learned representations and find that they\r\nare simultaneously
    useful on a diverse suite of tasks, including generalization\r\nunder covariate
    shifts, fairness, and abstract reasoning. Overall, our results\r\ndemonstrate
    that weak supervision enables learning of useful disentangled\r\nrepresentations
    in realistic scenarios."
alternative_title:
- PMLR
article_processing_charge: No
arxiv: 1
author:
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
- first_name: Ben
  full_name: Poole, Ben
  last_name: Poole
- first_name: Gunnar
  full_name: Rätsch, Gunnar
  last_name: Rätsch
- first_name: Bernhard
  full_name: Schölkopf, Bernhard
  last_name: Schölkopf
- first_name: Olivier
  full_name: Bachem, Olivier
  last_name: Bachem
- first_name: Michael
  full_name: Tschannen, Michael
  last_name: Tschannen
citation:
  ama: 'Locatello F, Poole B, Rätsch G, Schölkopf B, Bachem O, Tschannen M. Weakly-supervised
    disentanglement without compromises. In: <i>Proceedings of the 37th International
    Conference on Machine Learning</i>. Vol 119. ; 2020:6348–6359.'
  apa: Locatello, F., Poole, B., Rätsch, G., Schölkopf, B., Bachem, O., &#38; Tschannen,
    M. (2020). Weakly-supervised disentanglement without compromises. In <i>Proceedings
    of the 37th International Conference on Machine Learning</i> (Vol. 119, pp. 6348–6359).
    Virtual.
  chicago: Locatello, Francesco, Ben Poole, Gunnar Rätsch, Bernhard Schölkopf, Olivier
    Bachem, and Michael Tschannen. “Weakly-Supervised Disentanglement without Compromises.”
    In <i>Proceedings of the 37th International Conference on Machine Learning</i>,
    119:6348–6359, 2020.
  ieee: F. Locatello, B. Poole, G. Rätsch, B. Schölkopf, O. Bachem, and M. Tschannen,
    “Weakly-supervised disentanglement without compromises,” in <i>Proceedings of
    the 37th International Conference on Machine Learning</i>, Virtual, 2020, vol.
    119, pp. 6348–6359.
  ista: Locatello F, Poole B, Rätsch G, Schölkopf B, Bachem O, Tschannen M. 2020.
    Weakly-supervised disentanglement without compromises. Proceedings of the 37th
    International Conference on Machine Learning. International Conference on Machine
    Learning, PMLR, vol. 119, 6348–6359.
  mla: Locatello, Francesco, et al. “Weakly-Supervised Disentanglement without Compromises.”
    <i>Proceedings of the 37th International Conference on Machine Learning</i>, vol.
    119, 2020, pp. 6348–6359.
  short: F. Locatello, B. Poole, G. Rätsch, B. Schölkopf, O. Bachem, M. Tschannen,
    in:, Proceedings of the 37th International Conference on Machine Learning, 2020,
    pp. 6348–6359.
conference:
  end_date: 2020-07-18
  location: Virtual
  name: International Conference on Machine Learning
  start_date: 2020-07-13
date_created: 2023-08-22T14:08:14Z
date_published: 2020-07-07T00:00:00Z
date_updated: 2023-09-12T07:59:29Z
day: '07'
department:
- _id: FrLo
extern: '1'
external_id:
  arxiv:
  - '2002.02886'
intvolume: '       119'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2002.02886
month: '07'
oa: 1
oa_version: Preprint
page: 6348–6359
publication: Proceedings of the 37th International Conference on Machine Learning
publication_status: published
quality_controlled: '1'
scopus_import: '1'
status: public
title: Weakly-supervised disentanglement without compromises
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 119
year: '2020'
...
