---
_id: '14179'
abstract:
- lang: eng
  text: Self-supervised representation learning has shown remarkable success in a
    number of domains. A common practice is to perform data augmentation via hand-crafted
    transformations intended to leave the semantics of the data invariant. We seek
    to understand the empirical success of this approach from a theoretical perspective.
    We formulate the augmentation process as a latent variable model by postulating
    a partition of the latent representation into a content component, which is assumed
    invariant to augmentation, and a style component, which is allowed to change.
    Unlike prior work on disentanglement and independent component analysis, we allow
    for both nontrivial statistical and causal dependencies in the latent space. We
    study the identifiability of the latent representation based on pairs of views
    of the observations and prove sufficient conditions that allow us to identify
    the invariant content partition up to an invertible mapping in both generative
    and discriminative settings. We find numerical simulations with dependent latent
    variables are consistent with our theory. Lastly, we introduce Causal3DIdent,
    a dataset of high-dimensional, visually complex images with rich causal dependencies,
    which we use to study the effect of data augmentations performed in practice.
article_processing_charge: No
arxiv: 1
author:
- first_name: Julius von
  full_name: Kügelgen, Julius von
  last_name: Kügelgen
- first_name: Yash
  full_name: Sharma, Yash
  last_name: Sharma
- first_name: Luigi
  full_name: Gresele, Luigi
  last_name: Gresele
- first_name: Wieland
  full_name: Brendel, Wieland
  last_name: Brendel
- first_name: Bernhard
  full_name: Schölkopf, Bernhard
  last_name: Schölkopf
- first_name: Michel
  full_name: Besserve, Michel
  last_name: Besserve
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
citation:
  ama: 'Kügelgen J von, Sharma Y, Gresele L, et al. Self-supervised learning with
    data augmentations provably isolates content from style. In: <i>Advances in Neural
    Information Processing Systems</i>. Vol 34. ; 2021:16451-16467.'
  apa: Kügelgen, J. von, Sharma, Y., Gresele, L., Brendel, W., Schölkopf, B., Besserve,
    M., &#38; Locatello, F. (2021). Self-supervised learning with data augmentations
    provably isolates content from style. In <i>Advances in Neural Information Processing
    Systems</i> (Vol. 34, pp. 16451–16467). Virtual.
  chicago: Kügelgen, Julius von, Yash Sharma, Luigi Gresele, Wieland Brendel, Bernhard
    Schölkopf, Michel Besserve, and Francesco Locatello. “Self-Supervised Learning
    with Data Augmentations Provably Isolates Content from Style.” In <i>Advances
    in Neural Information Processing Systems</i>, 34:16451–67, 2021.
  ieee: J. von Kügelgen <i>et al.</i>, “Self-supervised learning with data augmentations
    provably isolates content from style,” in <i>Advances in Neural Information Processing
    Systems</i>, Virtual, 2021, vol. 34, pp. 16451–16467.
  ista: 'Kügelgen J von, Sharma Y, Gresele L, Brendel W, Schölkopf B, Besserve M,
    Locatello F. 2021. Self-supervised learning with data augmentations provably isolates
    content from style. Advances in Neural Information Processing Systems. NeurIPS:
    Neural Information Processing Systems vol. 34, 16451–16467.'
  mla: Kügelgen, Julius von, et al. “Self-Supervised Learning with Data Augmentations
    Provably Isolates Content from Style.” <i>Advances in Neural Information Processing
    Systems</i>, vol. 34, 2021, pp. 16451–67.
  short: J. von Kügelgen, Y. Sharma, L. Gresele, W. Brendel, B. Schölkopf, M. Besserve,
    F. Locatello, in:, Advances in Neural Information Processing Systems, 2021, pp.
    16451–16467.
conference:
  end_date: 2021-12-10
  location: Virtual
  name: 'NeurIPS: Neural Information Processing Systems'
  start_date: 2021-12-07
date_created: 2023-08-22T14:04:36Z
date_published: 2021-06-08T00:00:00Z
date_updated: 2023-09-11T10:33:19Z
day: '08'
department:
- _id: FrLo
extern: '1'
external_id:
  arxiv:
  - '2106.04619'
intvolume: '        34'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2106.04619
month: '06'
oa: 1
oa_version: Preprint
page: 16451-16467
publication: Advances in Neural Information Processing Systems
publication_identifier:
  isbn:
  - '9781713845393'
publication_status: published
quality_controlled: '1'
status: public
title: Self-supervised learning with data augmentations provably isolates content
  from style
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2021'
...
---
_id: '14180'
abstract:
- lang: eng
  text: 'Modern neural network architectures can leverage large amounts of data to
    generalize well within the training distribution. However, they are less capable
    of systematic generalization to data drawn from unseen but related distributions,
    a feat that is hypothesized to require compositional reasoning and reuse of knowledge.
    In this work, we present Neural Interpreters, an architecture that factorizes
    inference in a self-attention network as a system of modules, which we call \emph{functions}.
    Inputs to the model are routed through a sequence of functions in a way that is
    end-to-end learned. The proposed architecture can flexibly compose computation
    along width and depth, and lends itself well to capacity extension after training.
    To demonstrate the versatility of Neural Interpreters, we evaluate it in two distinct
    settings: image classification and visual abstract reasoning on Raven Progressive
    Matrices. In the former, we show that Neural Interpreters perform on par with
    the vision transformer using fewer parameters, while being transferrable to a
    new task in a sample efficient manner. In the latter, we find that Neural Interpreters
    are competitive with respect to the state-of-the-art in terms of systematic generalization. '
article_processing_charge: No
arxiv: 1
author:
- first_name: Nasim
  full_name: Rahaman, Nasim
  last_name: Rahaman
- first_name: Muhammad Waleed
  full_name: Gondal, Muhammad Waleed
  last_name: Gondal
- first_name: Shruti
  full_name: Joshi, Shruti
  last_name: Joshi
- first_name: Peter
  full_name: Gehler, Peter
  last_name: Gehler
- first_name: Yoshua
  full_name: Bengio, Yoshua
  last_name: Bengio
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
- first_name: Bernhard
  full_name: Schölkopf, Bernhard
  last_name: Schölkopf
citation:
  ama: 'Rahaman N, Gondal MW, Joshi S, et al. Dynamic inference with neural interpreters.
    In: <i>Advances in Neural Information Processing Systems</i>. Vol 34. ; 2021:10985-10998.'
  apa: Rahaman, N., Gondal, M. W., Joshi, S., Gehler, P., Bengio, Y., Locatello, F.,
    &#38; Schölkopf, B. (2021). Dynamic inference with neural interpreters. In <i>Advances
    in Neural Information Processing Systems</i> (Vol. 34, pp. 10985–10998). Virtual.
  chicago: Rahaman, Nasim, Muhammad Waleed Gondal, Shruti Joshi, Peter Gehler, Yoshua
    Bengio, Francesco Locatello, and Bernhard Schölkopf. “Dynamic Inference with Neural
    Interpreters.” In <i>Advances in Neural Information Processing Systems</i>, 34:10985–98,
    2021.
  ieee: N. Rahaman <i>et al.</i>, “Dynamic inference with neural interpreters,” in
    <i>Advances in Neural Information Processing Systems</i>, Virtual, 2021, vol.
    34, pp. 10985–10998.
  ista: 'Rahaman N, Gondal MW, Joshi S, Gehler P, Bengio Y, Locatello F, Schölkopf
    B. 2021. Dynamic inference with neural interpreters. Advances in Neural Information
    Processing Systems. NeurIPS: Neural Information Processing Systems vol. 34, 10985–10998.'
  mla: Rahaman, Nasim, et al. “Dynamic Inference with Neural Interpreters.” <i>Advances
    in Neural Information Processing Systems</i>, vol. 34, 2021, pp. 10985–98.
  short: N. Rahaman, M.W. Gondal, S. Joshi, P. Gehler, Y. Bengio, F. Locatello, B.
    Schölkopf, in:, Advances in Neural Information Processing Systems, 2021, pp. 10985–10998.
conference:
  end_date: 2021-12-10
  location: Virtual
  name: 'NeurIPS: Neural Information Processing Systems'
  start_date: 2021-12-07
date_created: 2023-08-22T14:04:55Z
date_published: 2021-10-12T00:00:00Z
date_updated: 2023-09-11T11:33:46Z
day: '12'
department:
- _id: FrLo
extern: '1'
external_id:
  arxiv:
  - '2110.06399'
intvolume: '        34'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2110.06399
month: '10'
oa: 1
oa_version: Preprint
page: 10985-10998
publication: Advances in Neural Information Processing Systems
publication_identifier:
  isbn:
  - '9781713845393'
publication_status: published
quality_controlled: '1'
status: public
title: Dynamic inference with neural interpreters
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2021'
...
---
_id: '14181'
abstract:
- lang: eng
  text: Variational Inference makes a trade-off between the capacity of the variational
    family and the tractability of finding an approximate posterior distribution.
    Instead, Boosting Variational Inference allows practitioners to obtain increasingly
    good posterior approximations by spending more compute. The main obstacle to widespread
    adoption of Boosting Variational Inference is the amount of resources necessary
    to improve over a strong Variational Inference baseline. In our work, we trace
    this limitation back to the global curvature of the KL-divergence. We characterize
    how the global curvature impacts time and memory consumption, address the problem
    with the notion of local curvature, and provide a novel approximate backtracking
    algorithm for estimating local curvature. We give new theoretical convergence
    rates for our algorithms and provide experimental validation on synthetic and
    real-world datasets.
article_processing_charge: No
arxiv: 1
author:
- first_name: Gideon
  full_name: Dresdner, Gideon
  last_name: Dresdner
- first_name: Saurav
  full_name: Shekhar, Saurav
  last_name: Shekhar
- first_name: Fabian
  full_name: Pedregosa, Fabian
  last_name: Pedregosa
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
- first_name: Gunnar
  full_name: Rätsch, Gunnar
  last_name: Rätsch
citation:
  ama: 'Dresdner G, Shekhar S, Pedregosa F, Locatello F, Rätsch G. Boosting variational
    inference with locally adaptive step-sizes. In: <i>Proceedings of the Thirtieth
    International Joint Conference on Artificial Intelligence</i>. International Joint
    Conferences on Artificial Intelligence; 2021:2337-2343. doi:<a href="https://doi.org/10.24963/ijcai.2021/322">10.24963/ijcai.2021/322</a>'
  apa: 'Dresdner, G., Shekhar, S., Pedregosa, F., Locatello, F., &#38; Rätsch, G.
    (2021). Boosting variational inference with locally adaptive step-sizes. In <i>Proceedings
    of the Thirtieth International Joint Conference on Artificial Intelligence</i>
    (pp. 2337–2343). Montreal, Canada: International Joint Conferences on Artificial
    Intelligence. <a href="https://doi.org/10.24963/ijcai.2021/322">https://doi.org/10.24963/ijcai.2021/322</a>'
  chicago: Dresdner, Gideon, Saurav Shekhar, Fabian Pedregosa, Francesco Locatello,
    and Gunnar Rätsch. “Boosting Variational Inference with Locally Adaptive Step-Sizes.”
    In <i>Proceedings of the Thirtieth International Joint Conference on Artificial
    Intelligence</i>, 2337–43. International Joint Conferences on Artificial Intelligence,
    2021. <a href="https://doi.org/10.24963/ijcai.2021/322">https://doi.org/10.24963/ijcai.2021/322</a>.
  ieee: G. Dresdner, S. Shekhar, F. Pedregosa, F. Locatello, and G. Rätsch, “Boosting
    variational inference with locally adaptive step-sizes,” in <i>Proceedings of
    the Thirtieth International Joint Conference on Artificial Intelligence</i>, Montreal,
    Canada, 2021, pp. 2337–2343.
  ista: 'Dresdner G, Shekhar S, Pedregosa F, Locatello F, Rätsch G. 2021. Boosting
    variational inference with locally adaptive step-sizes. Proceedings of the Thirtieth
    International Joint Conference on Artificial Intelligence. IJCAI: International
    Joint Conference on Artificial Intelligence, 2337–2343.'
  mla: Dresdner, Gideon, et al. “Boosting Variational Inference with Locally Adaptive
    Step-Sizes.” <i>Proceedings of the Thirtieth International Joint Conference on
    Artificial Intelligence</i>, International Joint Conferences on Artificial Intelligence,
    2021, pp. 2337–43, doi:<a href="https://doi.org/10.24963/ijcai.2021/322">10.24963/ijcai.2021/322</a>.
  short: G. Dresdner, S. Shekhar, F. Pedregosa, F. Locatello, G. Rätsch, in:, Proceedings
    of the Thirtieth International Joint Conference on Artificial Intelligence, International
    Joint Conferences on Artificial Intelligence, 2021, pp. 2337–2343.
conference:
  end_date: 2021-08-27
  location: Montreal, Canada
  name: 'IJCAI: International Joint Conference on Artificial Intelligence'
  start_date: 2021-08-19
date_created: 2023-08-22T14:05:14Z
date_published: 2021-05-19T00:00:00Z
date_updated: 2023-09-11T11:14:30Z
day: '19'
department:
- _id: FrLo
doi: 10.24963/ijcai.2021/322
extern: '1'
external_id:
  arxiv:
  - '2105.09240'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2105.09240
month: '05'
oa: 1
oa_version: Published Version
page: 2337-2343
publication: Proceedings of the Thirtieth International Joint Conference on Artificial
  Intelligence
publication_identifier:
  eisbn:
  - '9780999241196'
publication_status: published
publisher: International Joint Conferences on Artificial Intelligence
quality_controlled: '1'
status: public
title: Boosting variational inference with locally adaptive step-sizes
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '14182'
abstract:
- lang: eng
  text: "When machine learning systems meet real world applications, accuracy is only\r\none
    of several requirements. In this paper, we assay a complementary\r\nperspective
    originating from the increasing availability of pre-trained and\r\nregularly improving
    state-of-the-art models. While new improved models develop\r\nat a fast pace,
    downstream tasks vary more slowly or stay constant. Assume that\r\nwe have a large
    unlabelled data set for which we want to maintain accurate\r\npredictions. Whenever
    a new and presumably better ML models becomes available,\r\nwe encounter two problems:
    (i) given a limited budget, which data points should\r\nbe re-evaluated using
    the new model?; and (ii) if the new predictions differ\r\nfrom the current ones,
    should we update? Problem (i) is about compute cost,\r\nwhich matters for very
    large data sets and models. Problem (ii) is about\r\nmaintaining consistency of
    the predictions, which can be highly relevant for\r\ndownstream applications;
    our demand is to avoid negative flips, i.e., changing\r\ncorrect to incorrect
    predictions. In this paper, we formalize the Prediction\r\nUpdate Problem and
    present an efficient probabilistic approach as answer to the\r\nabove questions.
    In extensive experiments on standard classification benchmark\r\ndata sets, we
    show that our method outperforms alternative strategies along key\r\nmetrics for
    backward-compatible prediction updates."
article_processing_charge: No
arxiv: 1
author:
- first_name: Frederik
  full_name: Träuble, Frederik
  last_name: Träuble
- first_name: Julius von
  full_name: Kügelgen, Julius von
  last_name: Kügelgen
- first_name: Matthäus
  full_name: Kleindessner, Matthäus
  last_name: Kleindessner
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
- first_name: Bernhard
  full_name: Schölkopf, Bernhard
  last_name: Schölkopf
- first_name: Peter
  full_name: Gehler, Peter
  last_name: Gehler
citation:
  ama: 'Träuble F, Kügelgen J von, Kleindessner M, Locatello F, Schölkopf B, Gehler
    P. Backward-compatible prediction updates: A probabilistic approach. In: <i>35th
    Conference on Neural Information Processing Systems</i>. Vol 34. ; 2021:116-128.'
  apa: 'Träuble, F., Kügelgen, J. von, Kleindessner, M., Locatello, F., Schölkopf,
    B., &#38; Gehler, P. (2021). Backward-compatible prediction updates: A probabilistic
    approach. In <i>35th Conference on Neural Information Processing Systems</i> (Vol.
    34, pp. 116–128). Virtual.'
  chicago: 'Träuble, Frederik, Julius von Kügelgen, Matthäus Kleindessner, Francesco
    Locatello, Bernhard Schölkopf, and Peter Gehler. “Backward-Compatible Prediction
    Updates: A Probabilistic Approach.” In <i>35th Conference on Neural Information
    Processing Systems</i>, 34:116–28, 2021.'
  ieee: 'F. Träuble, J. von Kügelgen, M. Kleindessner, F. Locatello, B. Schölkopf,
    and P. Gehler, “Backward-compatible prediction updates: A probabilistic approach,”
    in <i>35th Conference on Neural Information Processing Systems</i>, Virtual, 2021,
    vol. 34, pp. 116–128.'
  ista: 'Träuble F, Kügelgen J von, Kleindessner M, Locatello F, Schölkopf B, Gehler
    P. 2021. Backward-compatible prediction updates: A probabilistic approach. 35th
    Conference on Neural Information Processing Systems. NeurIPS: Neural Information
    Processing Systems vol. 34, 116–128.'
  mla: 'Träuble, Frederik, et al. “Backward-Compatible Prediction Updates: A Probabilistic
    Approach.” <i>35th Conference on Neural Information Processing Systems</i>, vol.
    34, 2021, pp. 116–28.'
  short: F. Träuble, J. von Kügelgen, M. Kleindessner, F. Locatello, B. Schölkopf,
    P. Gehler, in:, 35th Conference on Neural Information Processing Systems, 2021,
    pp. 116–128.
conference:
  end_date: 2021-12-10
  location: Virtual
  name: 'NeurIPS: Neural Information Processing Systems'
  start_date: 2021-12-07
date_created: 2023-08-22T14:05:41Z
date_published: 2021-07-02T00:00:00Z
date_updated: 2023-09-11T11:31:59Z
day: '02'
department:
- _id: FrLo
extern: '1'
external_id:
  arxiv:
  - '2107.01057'
intvolume: '        34'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2107.01057
month: '07'
oa: 1
oa_version: Preprint
page: 116-128
publication: 35th Conference on Neural Information Processing Systems
publication_identifier:
  isbn:
  - '9781713845393'
publication_status: published
quality_controlled: '1'
status: public
title: 'Backward-compatible prediction updates: A probabilistic approach'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2021'
...
---
_id: '14221'
abstract:
- lang: eng
  text: 'The world is structured in countless ways. It may be prudent to enforce corresponding
    structural properties to a learning algorithm''s solution, such as incorporating
    prior beliefs, natural constraints, or causal structures. Doing so may translate
    to faster, more accurate, and more flexible models, which may directly relate
    to real-world impact. In this dissertation, we consider two different research
    areas that concern structuring a learning algorithm''s solution: when the structure
    is known and when it has to be discovered.'
article_number: '2111.13693'
article_processing_charge: No
arxiv: 1
author:
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
citation:
  ama: Locatello F. Enforcing and discovering structure in machine learning. <i>arXiv</i>.
    doi:<a href="https://doi.org/10.48550/arXiv.2111.13693">10.48550/arXiv.2111.13693</a>
  apa: Locatello, F. (n.d.). Enforcing and discovering structure in machine learning.
    <i>arXiv</i>. <a href="https://doi.org/10.48550/arXiv.2111.13693">https://doi.org/10.48550/arXiv.2111.13693</a>
  chicago: Locatello, Francesco. “Enforcing and Discovering Structure in Machine Learning.”
    <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/arXiv.2111.13693">https://doi.org/10.48550/arXiv.2111.13693</a>.
  ieee: F. Locatello, “Enforcing and discovering structure in machine learning,” <i>arXiv</i>.
    .
  ista: Locatello F. Enforcing and discovering structure in machine learning. arXiv,
    2111.13693.
  mla: Locatello, Francesco. “Enforcing and Discovering Structure in Machine Learning.”
    <i>ArXiv</i>, 2111.13693, doi:<a href="https://doi.org/10.48550/arXiv.2111.13693">10.48550/arXiv.2111.13693</a>.
  short: F. Locatello, ArXiv (n.d.).
date_created: 2023-08-22T14:23:35Z
date_published: 2021-11-26T00:00:00Z
date_updated: 2023-09-12T07:04:44Z
day: '26'
department:
- _id: FrLo
doi: 10.48550/arXiv.2111.13693
extern: '1'
external_id:
  arxiv:
  - '2111.13693'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2111.13693
month: '11'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: submitted
status: public
title: Enforcing and discovering structure in machine learning
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '9002'
abstract:
- lang: eng
  text: ' We prove that, for the binary erasure channel (BEC), the polar-coding paradigm
    gives rise to codes that not only approach the Shannon limit but do so under the
    best possible scaling of their block length as a function of the gap to capacity.
    This result exhibits the first known family of binary codes that attain both optimal
    scaling and quasi-linear complexity of encoding and decoding. Our proof is based
    on the construction and analysis of binary polar codes with large kernels. When
    communicating reliably at rates within ε>0 of capacity, the code length n often
    scales as O(1/εμ), where the constant μ is called the scaling exponent. It is
    known that the optimal scaling exponent is μ=2, and it is achieved by random linear
    codes. The scaling exponent of conventional polar codes (based on the 2×2 kernel)
    on the BEC is μ=3.63. This falls far short of the optimal scaling guaranteed by
    random codes. Our main contribution is a rigorous proof of the following result:
    for the BEC, there exist ℓ×ℓ binary kernels, such that polar codes constructed
    from these kernels achieve scaling exponent μ(ℓ) that tends to the optimal value
    of 2 as ℓ grows. We furthermore characterize precisely how large ℓ needs to be
    as a function of the gap between μ(ℓ) and 2. The resulting binary codes maintain
    the recursive structure of conventional polar codes, and thereby achieve construction
    complexity O(n) and encoding/decoding complexity O(nlogn).'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Arman
  full_name: Fazeli, Arman
  last_name: Fazeli
- first_name: Hamed
  full_name: Hassani, Hamed
  last_name: Hassani
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
- first_name: Alexander
  full_name: Vardy, Alexander
  last_name: Vardy
citation:
  ama: 'Fazeli A, Hassani H, Mondelli M, Vardy A. Binary linear codes with optimal
    scaling: Polar codes with large kernels. <i>IEEE Transactions on Information Theory</i>.
    2021;67(9):5693-5710. doi:<a href="https://doi.org/10.1109/TIT.2020.3038806">10.1109/TIT.2020.3038806</a>'
  apa: 'Fazeli, A., Hassani, H., Mondelli, M., &#38; Vardy, A. (2021). Binary linear
    codes with optimal scaling: Polar codes with large kernels. <i>IEEE Transactions
    on Information Theory</i>. IEEE. <a href="https://doi.org/10.1109/TIT.2020.3038806">https://doi.org/10.1109/TIT.2020.3038806</a>'
  chicago: 'Fazeli, Arman, Hamed Hassani, Marco Mondelli, and Alexander Vardy. “Binary
    Linear Codes with Optimal Scaling: Polar Codes with Large Kernels.” <i>IEEE Transactions
    on Information Theory</i>. IEEE, 2021. <a href="https://doi.org/10.1109/TIT.2020.3038806">https://doi.org/10.1109/TIT.2020.3038806</a>.'
  ieee: 'A. Fazeli, H. Hassani, M. Mondelli, and A. Vardy, “Binary linear codes with
    optimal scaling: Polar codes with large kernels,” <i>IEEE Transactions on Information
    Theory</i>, vol. 67, no. 9. IEEE, pp. 5693–5710, 2021.'
  ista: 'Fazeli A, Hassani H, Mondelli M, Vardy A. 2021. Binary linear codes with
    optimal scaling: Polar codes with large kernels. IEEE Transactions on Information
    Theory. 67(9), 5693–5710.'
  mla: 'Fazeli, Arman, et al. “Binary Linear Codes with Optimal Scaling: Polar Codes
    with Large Kernels.” <i>IEEE Transactions on Information Theory</i>, vol. 67,
    no. 9, IEEE, 2021, pp. 5693–710, doi:<a href="https://doi.org/10.1109/TIT.2020.3038806">10.1109/TIT.2020.3038806</a>.'
  short: A. Fazeli, H. Hassani, M. Mondelli, A. Vardy, IEEE Transactions on Information
    Theory 67 (2021) 5693–5710.
date_created: 2021-01-10T23:01:18Z
date_published: 2021-09-01T00:00:00Z
date_updated: 2024-03-07T12:18:50Z
day: '01'
department:
- _id: MaMo
doi: 10.1109/TIT.2020.3038806
external_id:
  arxiv:
  - '1711.01339'
intvolume: '        67'
issue: '9'
language:
- iso: eng
month: '09'
oa_version: Preprint
page: 5693-5710
publication: IEEE Transactions on Information Theory
publication_identifier:
  eissn:
  - 1557-9654
  issn:
  - 0018-9448
publication_status: published
publisher: IEEE
quality_controlled: '1'
related_material:
  record:
  - id: '6665'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: 'Binary linear codes with optimal scaling: Polar codes with large kernels'
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 67
year: '2021'
...
---
_id: '9005'
abstract:
- lang: eng
  text: Studies on the experimental realization of two-dimensional anyons in terms
    of quasiparticles have been restricted, so far, to only anyons on the plane. It
    is known, however, that the geometry and topology of space can have significant
    effects on quantum statistics for particles moving on it. Here, we have undertaken
    the first step toward realizing the emerging fractional statistics for particles
    restricted to move on the sphere instead of on the plane. We show that such a
    model arises naturally in the context of quantum impurity problems. In particular,
    we demonstrate a setup in which the lowest-energy spectrum of two linear bosonic
    or fermionic molecules immersed in a quantum many-particle environment can coincide
    with the anyonic spectrum on the sphere. This paves the way toward the experimental
    realization of anyons on the sphere using molecular impurities. Furthermore, since
    a change in the alignment of the molecules corresponds to the exchange of the
    particles on the sphere, such a realization reveals a novel type of exclusion
    principle for molecular impurities, which could also be of use as a powerful technique
    to measure the statistics parameter. Finally, our approach opens up a simple numerical
    route to investigate the spectra of many anyons on the sphere. Accordingly, we
    present the spectrum of two anyons on the sphere in the presence of a Dirac monopole
    field.
acknowledgement: "We are grateful to A. Ghazaryan for valuable discussions and also
  thank the anonymous referees for comments. D.L. acknowledges financial support from
  the G¨oran Gustafsson Foundation (grant no. 1804) and LMU Munich. M.L. gratefully
  acknowledges financial support\r\nby the European Research Council (ERC) under the
  European Union’s Horizon 2020 research and innovation programme (grant agreements
  No 801770)."
article_number: '015301'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Morris
  full_name: Brooks, Morris
  id: B7ECF9FC-AA38-11E9-AC9A-0930E6697425
  last_name: Brooks
  orcid: 0000-0002-6249-0928
- first_name: Mikhail
  full_name: Lemeshko, Mikhail
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
- first_name: D.
  full_name: Lundholm, D.
  last_name: Lundholm
- first_name: Enderalp
  full_name: Yakaboylu, Enderalp
  id: 38CB71F6-F248-11E8-B48F-1D18A9856A87
  last_name: Yakaboylu
  orcid: 0000-0001-5973-0874
citation:
  ama: Brooks M, Lemeshko M, Lundholm D, Yakaboylu E. Molecular impurities as a realization
    of anyons on the two-sphere. <i>Physical Review Letters</i>. 2021;126(1). doi:<a
    href="https://doi.org/10.1103/PhysRevLett.126.015301">10.1103/PhysRevLett.126.015301</a>
  apa: Brooks, M., Lemeshko, M., Lundholm, D., &#38; Yakaboylu, E. (2021). Molecular
    impurities as a realization of anyons on the two-sphere. <i>Physical Review Letters</i>.
    American Physical Society. <a href="https://doi.org/10.1103/PhysRevLett.126.015301">https://doi.org/10.1103/PhysRevLett.126.015301</a>
  chicago: Brooks, Morris, Mikhail Lemeshko, D. Lundholm, and Enderalp Yakaboylu.
    “Molecular Impurities as a Realization of Anyons on the Two-Sphere.” <i>Physical
    Review Letters</i>. American Physical Society, 2021. <a href="https://doi.org/10.1103/PhysRevLett.126.015301">https://doi.org/10.1103/PhysRevLett.126.015301</a>.
  ieee: M. Brooks, M. Lemeshko, D. Lundholm, and E. Yakaboylu, “Molecular impurities
    as a realization of anyons on the two-sphere,” <i>Physical Review Letters</i>,
    vol. 126, no. 1. American Physical Society, 2021.
  ista: Brooks M, Lemeshko M, Lundholm D, Yakaboylu E. 2021. Molecular impurities
    as a realization of anyons on the two-sphere. Physical Review Letters. 126(1),
    015301.
  mla: Brooks, Morris, et al. “Molecular Impurities as a Realization of Anyons on
    the Two-Sphere.” <i>Physical Review Letters</i>, vol. 126, no. 1, 015301, American
    Physical Society, 2021, doi:<a href="https://doi.org/10.1103/PhysRevLett.126.015301">10.1103/PhysRevLett.126.015301</a>.
  short: M. Brooks, M. Lemeshko, D. Lundholm, E. Yakaboylu, Physical Review Letters
    126 (2021).
date_created: 2021-01-17T23:01:10Z
date_published: 2021-01-08T00:00:00Z
date_updated: 2023-08-07T13:32:10Z
day: '08'
department:
- _id: MiLe
- _id: RoSe
doi: 10.1103/PhysRevLett.126.015301
ec_funded: 1
external_id:
  arxiv:
  - '2009.05948'
  isi:
  - '000606325000003'
intvolume: '       126'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2009.05948
month: '01'
oa: 1
oa_version: Preprint
project:
- _id: 2688CF98-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '801770'
  name: 'Angulon: physics and applications of a new quasiparticle'
publication: Physical Review Letters
publication_identifier:
  eissn:
  - '10797114'
  issn:
  - '00319007'
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/dancing-molecules-and-two-dimensional-particles/
  record:
  - id: '12390'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Molecular impurities as a realization of anyons on the two-sphere
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 126
year: '2021'
...
---
_id: '9006'
abstract:
- lang: eng
  text: Cytoplasm is a gel-like crowded environment composed of various macromolecules,
    organelles, cytoskeletal networks, and cytosol. The structure of the cytoplasm
    is highly organized and heterogeneous due to the crowding of its constituents
    and their effective compartmentalization. In such an environment, the diffusive
    dynamics of the molecules are restricted, an effect that is further amplified
    by clustering and anchoring of molecules. Despite the crowded nature of the cytoplasm
    at the microscopic scale, large-scale reorganization of the cytoplasm is essential
    for important cellular functions, such as cell division and polarization. How
    such mesoscale reorganization of the cytoplasm is achieved, especially for large
    cells such as oocytes or syncytial tissues that can span hundreds of micrometers
    in size, is only beginning to be understood. In this review, we will discuss recent
    advances in elucidating the molecular, cellular, and biophysical mechanisms by
    which the cytoskeleton drives cytoplasmic reorganization across different scales,
    structures, and species.
acknowledgement: We would like to thank Justine Renno for illustrations and Edouard
  Hannezo and members of the Heisenberg group for their comments on previous versions
  of the manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Shayan
  full_name: Shamipour, Shayan
  id: 40B34FE2-F248-11E8-B48F-1D18A9856A87
  last_name: Shamipour
- first_name: Silvia
  full_name: Caballero Mancebo, Silvia
  id: 2F1E1758-F248-11E8-B48F-1D18A9856A87
  last_name: Caballero Mancebo
  orcid: 0000-0002-5223-3346
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Shamipour S, Caballero Mancebo S, Heisenberg C-PJ. Cytoplasm’s got moves. <i>Developmental
    Cell</i>. 2021;56(2):P213-226. doi:<a href="https://doi.org/10.1016/j.devcel.2020.12.002">10.1016/j.devcel.2020.12.002</a>
  apa: Shamipour, S., Caballero Mancebo, S., &#38; Heisenberg, C.-P. J. (2021). Cytoplasm’s
    got moves. <i>Developmental Cell</i>. Elsevier. <a href="https://doi.org/10.1016/j.devcel.2020.12.002">https://doi.org/10.1016/j.devcel.2020.12.002</a>
  chicago: Shamipour, Shayan, Silvia Caballero Mancebo, and Carl-Philipp J Heisenberg.
    “Cytoplasm’s Got Moves.” <i>Developmental Cell</i>. Elsevier, 2021. <a href="https://doi.org/10.1016/j.devcel.2020.12.002">https://doi.org/10.1016/j.devcel.2020.12.002</a>.
  ieee: S. Shamipour, S. Caballero Mancebo, and C.-P. J. Heisenberg, “Cytoplasm’s
    got moves,” <i>Developmental Cell</i>, vol. 56, no. 2. Elsevier, pp. P213-226,
    2021.
  ista: Shamipour S, Caballero Mancebo S, Heisenberg C-PJ. 2021. Cytoplasm’s got moves.
    Developmental Cell. 56(2), P213-226.
  mla: Shamipour, Shayan, et al. “Cytoplasm’s Got Moves.” <i>Developmental Cell</i>,
    vol. 56, no. 2, Elsevier, 2021, pp. P213-226, doi:<a href="https://doi.org/10.1016/j.devcel.2020.12.002">10.1016/j.devcel.2020.12.002</a>.
  short: S. Shamipour, S. Caballero Mancebo, C.-P.J. Heisenberg, Developmental Cell
    56 (2021) P213-226.
date_created: 2021-01-17T23:01:10Z
date_published: 2021-01-25T00:00:00Z
date_updated: 2024-03-25T23:30:10Z
day: '25'
department:
- _id: CaHe
doi: 10.1016/j.devcel.2020.12.002
external_id:
  isi:
  - '000613273900009'
  pmid:
  - '33321104'
intvolume: '        56'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.devcel.2020.12.002
month: '01'
oa: 1
oa_version: Published Version
page: P213-226
pmid: 1
publication: Developmental Cell
publication_identifier:
  eissn:
  - '18781551'
  issn:
  - '15345807'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  record:
  - id: '9623'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Cytoplasm's got moves
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 56
year: '2021'
...
---
_id: '9009'
abstract:
- lang: eng
  text: Recent advancements in live cell imaging technologies have identified the
    phenomenon of intracellular propagation of late apoptotic events, such as cytochrome
    c release and caspase activation. The mechanism, prevalence, and speed of apoptosis
    propagation remain unclear. Additionally, no studies have demonstrated propagation
    of the pro-apoptotic protein, BAX. To evaluate the role of BAX in intracellular
    apoptotic propagation, we used high speed live-cell imaging to visualize fluorescently
    tagged-BAX recruitment to mitochondria in four immortalized cell lines. We show
    that propagation of mitochondrial BAX recruitment occurs in parallel to cytochrome
    c and SMAC/Diablo release and is affected by cellular morphology, such that cells
    with processes are more likely to exhibit propagation. The initiation of propagation
    events is most prevalent in the distal tips of processes, while the rate of propagation
    is influenced by the 2-dimensional width of the process. Propagation was rarely
    observed in the cell soma, which exhibited near synchronous recruitment of BAX.
    Propagation velocity is not affected by mitochondrial volume in segments of processes,
    but is negatively affected by mitochondrial density. There was no evidence of
    a propagating wave of increased levels of intracellular calcium ions. Alternatively,
    we did observe a uniform increase in superoxide build-up in cellular mitochondria,
    which was released as a propagating wave simultaneously with the propagating recruitment
    of BAX to the mitochondrial outer membrane.
acknowledgement: This work was supported by National Institute of Health grants R01
  EY030123, P30 EY016665, and T32 GM081061, an unrestricted research grant from Research
  to Prevent Blindness, Inc., and the Frederick A. Davis Endowment from the Department
  of Ophthalmology and Visual Sciences at the University of Wisconsin-Madison.
article_processing_charge: No
article_type: original
author:
- first_name: Joshua A.
  full_name: Grosser, Joshua A.
  last_name: Grosser
- first_name: Margaret E
  full_name: Maes, Margaret E
  id: 3838F452-F248-11E8-B48F-1D18A9856A87
  last_name: Maes
  orcid: 0000-0001-9642-1085
- first_name: Robert W.
  full_name: Nickells, Robert W.
  last_name: Nickells
citation:
  ama: Grosser JA, Maes ME, Nickells RW. Characteristics of intracellular propagation
    of mitochondrial BAX recruitment during apoptosis. <i>Apoptosis</i>. 2021;26(2):132-145.
    doi:<a href="https://doi.org/10.1007/s10495-020-01654-w">10.1007/s10495-020-01654-w</a>
  apa: Grosser, J. A., Maes, M. E., &#38; Nickells, R. W. (2021). Characteristics
    of intracellular propagation of mitochondrial BAX recruitment during apoptosis.
    <i>Apoptosis</i>. Springer Nature. <a href="https://doi.org/10.1007/s10495-020-01654-w">https://doi.org/10.1007/s10495-020-01654-w</a>
  chicago: Grosser, Joshua A., Margaret E Maes, and Robert W. Nickells. “Characteristics
    of Intracellular Propagation of Mitochondrial BAX Recruitment during Apoptosis.”
    <i>Apoptosis</i>. Springer Nature, 2021. <a href="https://doi.org/10.1007/s10495-020-01654-w">https://doi.org/10.1007/s10495-020-01654-w</a>.
  ieee: J. A. Grosser, M. E. Maes, and R. W. Nickells, “Characteristics of intracellular
    propagation of mitochondrial BAX recruitment during apoptosis,” <i>Apoptosis</i>,
    vol. 26, no. 2. Springer Nature, pp. 132–145, 2021.
  ista: Grosser JA, Maes ME, Nickells RW. 2021. Characteristics of intracellular propagation
    of mitochondrial BAX recruitment during apoptosis. Apoptosis. 26(2), 132–145.
  mla: Grosser, Joshua A., et al. “Characteristics of Intracellular Propagation of
    Mitochondrial BAX Recruitment during Apoptosis.” <i>Apoptosis</i>, vol. 26, no.
    2, Springer Nature, 2021, pp. 132–45, doi:<a href="https://doi.org/10.1007/s10495-020-01654-w">10.1007/s10495-020-01654-w</a>.
  short: J.A. Grosser, M.E. Maes, R.W. Nickells, Apoptosis 26 (2021) 132–145.
date_created: 2021-01-17T23:01:11Z
date_published: 2021-02-01T00:00:00Z
date_updated: 2023-08-07T13:32:40Z
day: '01'
department:
- _id: SaSi
doi: 10.1007/s10495-020-01654-w
external_id:
  isi:
  - '000606722600001'
  pmid:
  - '33426618'
intvolume: '        26'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082518/
month: '02'
oa: 1
oa_version: Submitted Version
page: 132-145
pmid: 1
publication: Apoptosis
publication_identifier:
  eissn:
  - 1573-675X
  issn:
  - 1360-8185
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Characteristics of intracellular propagation of mitochondrial BAX recruitment
  during apoptosis
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 26
year: '2021'
...
---
_id: '9010'
abstract:
- lang: eng
  text: Availability of the essential macronutrient nitrogen in soil plays a critical
    role in plant growth, development, and impacts agricultural productivity. Plants
    have evolved different strategies for sensing and responding to heterogeneous
    nitrogen distribution. Modulation of root system architecture, including primary
    root growth and branching, is among the most essential plant adaptions to ensure
    adequate nitrogen acquisition. However, the immediate molecular pathways coordinating
    the adjustment of root growth in response to distinct nitrogen sources, such as
    nitrate or ammonium, are poorly understood. Here, we show that growth as manifested
    by cell division and elongation is synchronized by coordinated auxin flux between
    two adjacent outer tissue layers of the root. This coordination is achieved by
    nitrate‐dependent dephosphorylation of the PIN2 auxin efflux carrier at a previously
    uncharacterized phosphorylation site, leading to subsequent PIN2 lateralization
    and thereby regulating auxin flow between adjacent tissues. A dynamic computer
    model based on our experimental data successfully recapitulates experimental observations.
    Our study provides mechanistic insights broadening our understanding of root growth
    mechanisms in dynamic environments.
acknowledged_ssus:
- _id: Bio
acknowledgement: 'We acknowledge Gergely Molnar for critical reading of the manuscript,
  Alexander Johnson for language editing and Yulija Salanenka for technical assistance.
  Work in the Benkova laboratory was supported by the Austrian Science Fund (FWF01_I1774S)
  to KO, RA and EB. Work in the Benkova laboratory was supported by the Austrian Science
  Fund (FWF01_I1774S) to KO, RA and EB and by the DOC Fellowship Programme of the
  AustrianAcademy of Sciences (25008) to C.A. Work in the Wabnik laboratory was supported
  by the Programa de Atraccion de Talento 2017 (Comunidad deMadrid, 2017-T1/BIO-5654
  to K.W.), Severo Ochoa Programme for Centres of Excellence in R&D from the Agencia
  Estatal de Investigacion of Spain (grantSEV-2016-0672 (2017-2021) to K.W. via the
  CBGP) and Programa Estatal de Generacion del Conocimiento y Fortalecimiento Científico
  y Tecnologico del Sistema de I+D+I 2019 (PGC2018-093387-A-I00) from MICIU (to K.W.).
  M.M.was supported by a postdoctoral contract associated to SEV-2016-0672.We acknowledge
  the Bioimaging Facility in IST-Austria and the Advanced Microscopy Facility of the
  Vienna Bio Center Core Facilities, member of the Vienna Bio Center Austria, for
  use of the OMX v43D SIM microscope. AJ was supported by the Austrian Science Fund
  (FWF): I03630 to J.F'
article_number: e106862
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Krisztina
  full_name: Ötvös, Krisztina
  id: 29B901B0-F248-11E8-B48F-1D18A9856A87
  last_name: Ötvös
  orcid: 0000-0002-5503-4983
- first_name: Marco
  full_name: Marconi, Marco
  last_name: Marconi
- first_name: Andrea
  full_name: Vega, Andrea
  last_name: Vega
- first_name: Jose
  full_name: O’Brien, Jose
  last_name: O’Brien
- first_name: Alexander J
  full_name: Johnson, Alexander J
  id: 46A62C3A-F248-11E8-B48F-1D18A9856A87
  last_name: Johnson
  orcid: 0000-0002-2739-8843
- first_name: Rashed
  full_name: Abualia, Rashed
  id: 4827E134-F248-11E8-B48F-1D18A9856A87
  last_name: Abualia
  orcid: 0000-0002-9357-9415
- first_name: Livio
  full_name: Antonielli, Livio
  last_name: Antonielli
- first_name: Juan C
  full_name: Montesinos López, Juan C
  id: 310A8E3E-F248-11E8-B48F-1D18A9856A87
  last_name: Montesinos López
  orcid: 0000-0001-9179-6099
- first_name: Yuzhou
  full_name: Zhang, Yuzhou
  id: 3B6137F2-F248-11E8-B48F-1D18A9856A87
  last_name: Zhang
  orcid: 0000-0003-2627-6956
- first_name: Shutang
  full_name: Tan, Shutang
  id: 2DE75584-F248-11E8-B48F-1D18A9856A87
  last_name: Tan
  orcid: 0000-0002-0471-8285
- first_name: Candela
  full_name: Cuesta, Candela
  id: 33A3C818-F248-11E8-B48F-1D18A9856A87
  last_name: Cuesta
  orcid: 0000-0003-1923-2410
- first_name: Christina
  full_name: Artner, Christina
  id: 45DF286A-F248-11E8-B48F-1D18A9856A87
  last_name: Artner
- first_name: Eleonore
  full_name: Bouguyon, Eleonore
  last_name: Bouguyon
- first_name: Alain
  full_name: Gojon, Alain
  last_name: Gojon
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Rodrigo A.
  full_name: Gutiérrez, Rodrigo A.
  last_name: Gutiérrez
- first_name: Krzysztof T
  full_name: Wabnik, Krzysztof T
  id: 4DE369A4-F248-11E8-B48F-1D18A9856A87
  last_name: Wabnik
  orcid: 0000-0001-7263-0560
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
citation:
  ama: Ötvös K, Marconi M, Vega A, et al. Modulation of plant root growth by nitrogen
    source-defined regulation of polar auxin transport. <i>EMBO Journal</i>. 2021;40(3).
    doi:<a href="https://doi.org/10.15252/embj.2020106862">10.15252/embj.2020106862</a>
  apa: Ötvös, K., Marconi, M., Vega, A., O’Brien, J., Johnson, A. J., Abualia, R.,
    … Benková, E. (2021). Modulation of plant root growth by nitrogen source-defined
    regulation of polar auxin transport. <i>EMBO Journal</i>. Embo Press. <a href="https://doi.org/10.15252/embj.2020106862">https://doi.org/10.15252/embj.2020106862</a>
  chicago: Ötvös, Krisztina, Marco Marconi, Andrea Vega, Jose O’Brien, Alexander J
    Johnson, Rashed Abualia, Livio Antonielli, et al. “Modulation of Plant Root Growth
    by Nitrogen Source-Defined Regulation of Polar Auxin Transport.” <i>EMBO Journal</i>.
    Embo Press, 2021. <a href="https://doi.org/10.15252/embj.2020106862">https://doi.org/10.15252/embj.2020106862</a>.
  ieee: K. Ötvös <i>et al.</i>, “Modulation of plant root growth by nitrogen source-defined
    regulation of polar auxin transport,” <i>EMBO Journal</i>, vol. 40, no. 3. Embo
    Press, 2021.
  ista: Ötvös K, Marconi M, Vega A, O’Brien J, Johnson AJ, Abualia R, Antonielli L,
    Montesinos López JC, Zhang Y, Tan S, Cuesta C, Artner C, Bouguyon E, Gojon A,
    Friml J, Gutiérrez RA, Wabnik KT, Benková E. 2021. Modulation of plant root growth
    by nitrogen source-defined regulation of polar auxin transport. EMBO Journal.
    40(3), e106862.
  mla: Ötvös, Krisztina, et al. “Modulation of Plant Root Growth by Nitrogen Source-Defined
    Regulation of Polar Auxin Transport.” <i>EMBO Journal</i>, vol. 40, no. 3, e106862,
    Embo Press, 2021, doi:<a href="https://doi.org/10.15252/embj.2020106862">10.15252/embj.2020106862</a>.
  short: K. Ötvös, M. Marconi, A. Vega, J. O’Brien, A.J. Johnson, R. Abualia, L. Antonielli,
    J.C. Montesinos López, Y. Zhang, S. Tan, C. Cuesta, C. Artner, E. Bouguyon, A.
    Gojon, J. Friml, R.A. Gutiérrez, K.T. Wabnik, E. Benková, EMBO Journal 40 (2021).
date_created: 2021-01-17T23:01:12Z
date_published: 2021-02-01T00:00:00Z
date_updated: 2024-03-25T23:30:22Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
- _id: EvBe
doi: 10.15252/embj.2020106862
external_id:
  isi:
  - '000604645600001'
  pmid:
  - ' 33399250'
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  file_id: '9110'
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  file_size: 2358617
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file_date_updated: 2021-02-11T12:28:29Z
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isi: 1
issue: '3'
language:
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month: '02'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 2542D156-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I 1774-B16
  name: Hormone cross-talk drives nutrient dependent plant development
- _id: 2685A872-B435-11E9-9278-68D0E5697425
  name: Hormonal regulation of plant adaptive responses to environmental signals
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
publication: EMBO Journal
publication_identifier:
  eissn:
  - '14602075'
  issn:
  - '02614189'
publication_status: published
publisher: Embo Press
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/a-plants-way-to-its-favorite-food/
  record:
  - id: '10303'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Modulation of plant root growth by nitrogen source-defined regulation of polar
  auxin transport
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 40
year: '2021'
...
---
_id: '9020'
abstract:
- lang: eng
  text: 'We study dynamics and thermodynamics of ion transport in narrow, water-filled
    channels, considered as effective 1D Coulomb systems. The long range nature of
    the inter-ion interactions comes about due to the dielectric constants mismatch
    between the water and the surrounding medium, confining the electric filed to
    stay mostly within the water-filled channel. Statistical mechanics of such Coulomb
    systems is dominated by entropic effects which may be accurately accounted for
    by mapping onto an effective quantum mechanics. In presence of multivalent ions
    the corresponding quantum mechanics appears to be non-Hermitian. In this review
    we discuss a framework for semiclassical calculations for the effective non-Hermitian
    Hamiltonians. Non-Hermiticity elevates WKB action integrals from the real line
    to closed cycles on a complex Riemann surfaces where direct calculations are not
    attainable. We circumvent this issue by applying tools from algebraic topology,
    such as the Picard-Fuchs equation. We discuss how its solutions relate to the
    thermodynamics and correlation functions of multivalent solutions within narrow,
    water-filled channels. '
acknowledgement: "A.K. was supported by NSF grants DMR-2037654. T.G. acknowledges
  funding from the Institute of Science and Technology (IST) Austria, and from the
  European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie
  Grant Agreement No. 754411.\r\nWe are indebted to Boris Shklovskii for introducing
  us to the problem, and Alexander Gorsky and Peter Koroteev for introducing us to
  the Picard-Fuchs methods. A very special thanks goes to Michael Janas for several
  years of excellent collaboration on these topics. TG thanks Michael Kreshchuk for
  introduction to the exact WKB method and great collaboration on related projects.
  Figure 3 and Figure 4 are reproduced from Reference [25] with friendly permission
  by the Russian Academy of Sciences. Figure 2, Figure 4, Figure 5, Figure 6, and
  Figure 8 are reproduced from Reference [26] with friendly permission by IOP Publishing."
article_number: e23010125
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Tobias
  full_name: Gulden, Tobias
  id: 1083E038-9F73-11E9-A4B5-532AE6697425
  last_name: Gulden
  orcid: 0000-0001-6814-7541
- first_name: Alex
  full_name: Kamenev, Alex
  last_name: Kamenev
citation:
  ama: Gulden T, Kamenev A. Dynamics of ion channels via non-hermitian quantum mechanics.
    <i>Entropy</i>. 2021;23(1). doi:<a href="https://doi.org/10.3390/e23010125">10.3390/e23010125</a>
  apa: Gulden, T., &#38; Kamenev, A. (2021). Dynamics of ion channels via non-hermitian
    quantum mechanics. <i>Entropy</i>. MDPI. <a href="https://doi.org/10.3390/e23010125">https://doi.org/10.3390/e23010125</a>
  chicago: Gulden, Tobias, and Alex Kamenev. “Dynamics of Ion Channels via Non-Hermitian
    Quantum Mechanics.” <i>Entropy</i>. MDPI, 2021. <a href="https://doi.org/10.3390/e23010125">https://doi.org/10.3390/e23010125</a>.
  ieee: T. Gulden and A. Kamenev, “Dynamics of ion channels via non-hermitian quantum
    mechanics,” <i>Entropy</i>, vol. 23, no. 1. MDPI, 2021.
  ista: Gulden T, Kamenev A. 2021. Dynamics of ion channels via non-hermitian quantum
    mechanics. Entropy. 23(1), e23010125.
  mla: Gulden, Tobias, and Alex Kamenev. “Dynamics of Ion Channels via Non-Hermitian
    Quantum Mechanics.” <i>Entropy</i>, vol. 23, no. 1, e23010125, MDPI, 2021, doi:<a
    href="https://doi.org/10.3390/e23010125">10.3390/e23010125</a>.
  short: T. Gulden, A. Kamenev, Entropy 23 (2021).
date_created: 2021-01-19T11:12:06Z
date_published: 2021-01-19T00:00:00Z
date_updated: 2023-08-07T13:34:18Z
day: '19'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.3390/e23010125
ec_funded: 1
external_id:
  arxiv:
  - '2012.01390'
  isi:
  - '000610122000001'
file:
- access_level: open_access
  checksum: 6cd0e706156827c45c740534bd32c179
  content_type: application/pdf
  creator: tgulden
  date_created: 2021-01-19T11:11:14Z
  date_updated: 2021-01-19T11:11:14Z
  file_id: '9021'
  file_name: Final published paper.pdf
  file_size: 981285
  relation: main_file
file_date_updated: 2021-01-19T11:11:14Z
has_accepted_license: '1'
intvolume: '        23'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Entropy
publication_identifier:
  eissn:
  - 1099-4300
publication_status: published
publisher: MDPI
quality_controlled: '1'
status: public
title: Dynamics of ion channels via non-hermitian quantum mechanics
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 23
year: '2021'
...
---
_id: '9022'
abstract:
- lang: eng
  text: "In the first part of the thesis we consider Hermitian random matrices. Firstly,
    we consider sample covariance matrices XX∗ with X having independent identically
    distributed (i.i.d.) centred entries. We prove a Central Limit Theorem for differences
    of linear statistics of XX∗ and its minor after removing the first column of X.
    Secondly, we consider Wigner-type matrices and prove that the eigenvalue statistics
    near cusp singularities of the limiting density of states are universal and that
    they form a Pearcey process. Since the limiting eigenvalue distribution admits
    only square root (edge) and cubic root (cusp) singularities, this concludes the
    third and last remaining case of the Wigner-Dyson-Mehta universality conjecture.
    The main technical ingredients are an optimal local law at the cusp, and the proof
    of the fast relaxation to equilibrium of the Dyson Brownian motion in the cusp
    regime.\r\nIn the second part we consider non-Hermitian matrices X with centred
    i.i.d. entries. We normalise the entries of X to have variance N −1. It is well
    known that the empirical eigenvalue density converges to the uniform distribution
    on the unit disk (circular law). In the first project, we prove universality of
    the local eigenvalue statistics close to the edge of the spectrum. This is the
    non-Hermitian analogue of the TracyWidom universality at the Hermitian edge. Technically
    we analyse the evolution of the spectral distribution of X along the Ornstein-Uhlenbeck
    flow for very long time\r\n(up to t = +∞). In the second project, we consider
    linear statistics of eigenvalues for macroscopic test functions f in the Sobolev
    space H2+ϵ and prove their convergence to the projection of the Gaussian Free
    Field on the unit disk. We prove this result for non-Hermitian matrices with real
    or complex entries. The main technical ingredients are: (i) local law for products
    of two resolvents at different spectral parameters, (ii) analysis of correlated
    Dyson Brownian motions.\r\nIn the third and final part we discuss the mathematically
    rigorous application of supersymmetric techniques (SUSY ) to give a lower tail
    estimate of the lowest singular value of X − z, with z ∈ C. More precisely, we
    use superbosonisation formula to give an integral representation of the resolvent
    of (X − z)(X − z)∗ which reduces to two and three contour integrals in the complex
    and real case, respectively. The rigorous analysis of these integrals is quite
    challenging since simple saddle point analysis cannot be applied (the main contribution
    comes from a non-trivial manifold). Our result\r\nimproves classical smoothing
    inequalities in the regime |z| ≈ 1; this result is essential to prove edge universality
    for i.i.d. non-Hermitian matrices."
acknowledgement: I gratefully acknowledge the financial support from the European
  Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie
  Grant Agreement No. 665385 and my advisor’s ERC Advanced Grant No. 338804.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Giorgio
  full_name: Cipolloni, Giorgio
  id: 42198EFA-F248-11E8-B48F-1D18A9856A87
  last_name: Cipolloni
  orcid: 0000-0002-4901-7992
citation:
  ama: Cipolloni G. Fluctuations in the spectrum of random matrices. 2021. doi:<a
    href="https://doi.org/10.15479/AT:ISTA:9022">10.15479/AT:ISTA:9022</a>
  apa: Cipolloni, G. (2021). <i>Fluctuations in the spectrum of random matrices</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:9022">https://doi.org/10.15479/AT:ISTA:9022</a>
  chicago: Cipolloni, Giorgio. “Fluctuations in the Spectrum of Random Matrices.”
    Institute of Science and Technology Austria, 2021. <a href="https://doi.org/10.15479/AT:ISTA:9022">https://doi.org/10.15479/AT:ISTA:9022</a>.
  ieee: G. Cipolloni, “Fluctuations in the spectrum of random matrices,” Institute
    of Science and Technology Austria, 2021.
  ista: Cipolloni G. 2021. Fluctuations in the spectrum of random matrices. Institute
    of Science and Technology Austria.
  mla: Cipolloni, Giorgio. <i>Fluctuations in the Spectrum of Random Matrices</i>.
    Institute of Science and Technology Austria, 2021, doi:<a href="https://doi.org/10.15479/AT:ISTA:9022">10.15479/AT:ISTA:9022</a>.
  short: G. Cipolloni, Fluctuations in the Spectrum of Random Matrices, Institute
    of Science and Technology Austria, 2021.
date_created: 2021-01-21T18:16:54Z
date_published: 2021-01-25T00:00:00Z
date_updated: 2023-09-07T13:29:32Z
day: '25'
ddc:
- '510'
degree_awarded: PhD
department:
- _id: GradSch
- _id: LaEr
doi: 10.15479/AT:ISTA:9022
ec_funded: 1
file:
- access_level: open_access
  checksum: 5a93658a5f19478372523ee232887e2b
  content_type: application/pdf
  creator: gcipollo
  date_created: 2021-01-25T14:19:03Z
  date_updated: 2021-01-25T14:19:03Z
  file_id: '9043'
  file_name: thesis.pdf
  file_size: 4127796
  relation: main_file
  success: 1
- access_level: closed
  checksum: e8270eddfe6a988e92a53c88d1d19b8c
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  creator: gcipollo
  date_created: 2021-01-25T14:19:10Z
  date_updated: 2021-01-25T14:19:10Z
  file_id: '9044'
  file_name: Thesis_files.zip
  file_size: 12775206
  relation: source_file
file_date_updated: 2021-01-25T14:19:10Z
has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: '380'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
title: Fluctuations in the spectrum of random matrices
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2021'
...
---
_id: '9036'
abstract:
- lang: eng
  text: In this short note, we prove that the square root of the quantum Jensen-Shannon
    divergence is a true metric on the cone of positive matrices, and hence in particular
    on the quantum state space.
acknowledgement: D. Virosztek was supported by the European Union's Horizon 2020 research
  and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 846294,
  and partially supported by the Hungarian National Research, Development and Innovation
  Office (NKFIH) via grants no. K124152, and no. KH129601.
article_number: '107595'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Daniel
  full_name: Virosztek, Daniel
  id: 48DB45DA-F248-11E8-B48F-1D18A9856A87
  last_name: Virosztek
  orcid: 0000-0003-1109-5511
citation:
  ama: Virosztek D. The metric property of the quantum Jensen-Shannon divergence.
    <i>Advances in Mathematics</i>. 2021;380(3). doi:<a href="https://doi.org/10.1016/j.aim.2021.107595">10.1016/j.aim.2021.107595</a>
  apa: Virosztek, D. (2021). The metric property of the quantum Jensen-Shannon divergence.
    <i>Advances in Mathematics</i>. Elsevier. <a href="https://doi.org/10.1016/j.aim.2021.107595">https://doi.org/10.1016/j.aim.2021.107595</a>
  chicago: Virosztek, Daniel. “The Metric Property of the Quantum Jensen-Shannon Divergence.”
    <i>Advances in Mathematics</i>. Elsevier, 2021. <a href="https://doi.org/10.1016/j.aim.2021.107595">https://doi.org/10.1016/j.aim.2021.107595</a>.
  ieee: D. Virosztek, “The metric property of the quantum Jensen-Shannon divergence,”
    <i>Advances in Mathematics</i>, vol. 380, no. 3. Elsevier, 2021.
  ista: Virosztek D. 2021. The metric property of the quantum Jensen-Shannon divergence.
    Advances in Mathematics. 380(3), 107595.
  mla: Virosztek, Daniel. “The Metric Property of the Quantum Jensen-Shannon Divergence.”
    <i>Advances in Mathematics</i>, vol. 380, no. 3, 107595, Elsevier, 2021, doi:<a
    href="https://doi.org/10.1016/j.aim.2021.107595">10.1016/j.aim.2021.107595</a>.
  short: D. Virosztek, Advances in Mathematics 380 (2021).
date_created: 2021-01-22T17:55:17Z
date_published: 2021-03-26T00:00:00Z
date_updated: 2023-08-07T13:34:48Z
day: '26'
department:
- _id: LaEr
doi: 10.1016/j.aim.2021.107595
ec_funded: 1
external_id:
  arxiv:
  - '1910.10447'
  isi:
  - '000619676100035'
intvolume: '       380'
isi: 1
issue: '3'
keyword:
- General Mathematics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1910.10447
month: '03'
oa: 1
oa_version: Preprint
project:
- _id: 26A455A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '846294'
  name: Geometric study of Wasserstein spaces and free probability
publication: Advances in Mathematics
publication_identifier:
  issn:
  - 0001-8708
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: The metric property of the quantum Jensen-Shannon divergence
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 380
year: '2021'
...
---
_id: '9037'
abstract:
- lang: eng
  text: "We continue our study of ‘no‐dimension’ analogues of basic theorems in combinatorial
    and convex geometry in Banach spaces. We generalize some results of the paper
    (Adiprasito, Bárány and Mustafa, ‘Theorems of Carathéodory, Helly, and Tverberg
    without dimension’, Proceedings of the Thirtieth Annual ACM‐SIAM Symposium on
    Discrete Algorithms (Society for Industrial and Applied Mathematics, San Diego,
    California, 2019) 2350–2360) and prove no‐dimension versions of the colored Tverberg
    theorem, the selection lemma and the weak  \U0001D700 ‐net theorem in Banach spaces
    of type  \U0001D45D>1 . To prove these results, we use the original ideas of Adiprasito,
    Bárány and Mustafa for the Euclidean case, our no‐dimension version of the Radon
    theorem and slightly modified version of the celebrated Maurey lemma."
acknowledgement: "I wish to thank Imre Bárány for bringing the problem to my attention.
  I am grateful to Marton Naszódi and Igor Tsiutsiurupa for useful remarks and help
  with the text.\r\nThe author acknowledges the financial support from the Ministry
  of Educational and Science of the Russian Federation in the framework of MegaGrant
  no 075‐15‐2019‐1926."
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Grigory
  full_name: Ivanov, Grigory
  id: 87744F66-5C6F-11EA-AFE0-D16B3DDC885E
  last_name: Ivanov
citation:
  ama: Ivanov G. No-dimension Tverberg’s theorem and its corollaries in Banach spaces
    of type p. <i>Bulletin of the London Mathematical Society</i>. 2021;53(2):631-641.
    doi:<a href="https://doi.org/10.1112/blms.12449">10.1112/blms.12449</a>
  apa: Ivanov, G. (2021). No-dimension Tverberg’s theorem and its corollaries in Banach
    spaces of type p. <i>Bulletin of the London Mathematical Society</i>. London Mathematical
    Society. <a href="https://doi.org/10.1112/blms.12449">https://doi.org/10.1112/blms.12449</a>
  chicago: Ivanov, Grigory. “No-Dimension Tverberg’s Theorem and Its Corollaries in
    Banach Spaces of Type P.” <i>Bulletin of the London Mathematical Society</i>.
    London Mathematical Society, 2021. <a href="https://doi.org/10.1112/blms.12449">https://doi.org/10.1112/blms.12449</a>.
  ieee: G. Ivanov, “No-dimension Tverberg’s theorem and its corollaries in Banach
    spaces of type p,” <i>Bulletin of the London Mathematical Society</i>, vol. 53,
    no. 2. London Mathematical Society, pp. 631–641, 2021.
  ista: Ivanov G. 2021. No-dimension Tverberg’s theorem and its corollaries in Banach
    spaces of type p. Bulletin of the London Mathematical Society. 53(2), 631–641.
  mla: Ivanov, Grigory. “No-Dimension Tverberg’s Theorem and Its Corollaries in Banach
    Spaces of Type P.” <i>Bulletin of the London Mathematical Society</i>, vol. 53,
    no. 2, London Mathematical Society, 2021, pp. 631–41, doi:<a href="https://doi.org/10.1112/blms.12449">10.1112/blms.12449</a>.
  short: G. Ivanov, Bulletin of the London Mathematical Society 53 (2021) 631–641.
date_created: 2021-01-24T23:01:08Z
date_published: 2021-04-01T00:00:00Z
date_updated: 2023-08-07T13:35:20Z
day: '01'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.1112/blms.12449
external_id:
  arxiv:
  - '1912.08561'
  isi:
  - '000607265100001'
file:
- access_level: open_access
  checksum: e6ceaa6470d835eb4c211cbdd38fdfd1
  content_type: application/pdf
  creator: kschuh
  date_created: 2021-08-06T09:59:45Z
  date_updated: 2021-08-06T09:59:45Z
  file_id: '9796'
  file_name: 2021_BLMS_Ivanov.pdf
  file_size: 194550
  relation: main_file
  success: 1
file_date_updated: 2021-08-06T09:59:45Z
has_accepted_license: '1'
intvolume: '        53'
isi: 1
issue: '2'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '04'
oa: 1
oa_version: Published Version
page: 631-641
publication: Bulletin of the London Mathematical Society
publication_identifier:
  eissn:
  - '14692120'
  issn:
  - '00246093'
publication_status: published
publisher: London Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: No-dimension Tverberg's theorem and its corollaries in Banach spaces of type
  p
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 53
year: '2021'
...
---
_id: '9046'
acknowledgement: Our work was supported by the Swedish Research Council (grant 2017-01527)
  to DIA
article_number: e1009172
article_processing_charge: No
article_type: original
author:
- first_name: Roderich
  full_name: Römhild, Roderich
  id: 68E56E44-62B0-11EA-B963-444F3DDC885E
  last_name: Römhild
  orcid: 0000-0001-9480-5261
- first_name: Dan I.
  full_name: Andersson, Dan I.
  last_name: Andersson
citation:
  ama: Römhild R, Andersson DI. Mechanisms and therapeutic potential of collateral
    sensitivity to antibiotics. <i>PLoS Pathogens</i>. 2021;17(1). doi:<a href="https://doi.org/10.1371/journal.ppat.1009172">10.1371/journal.ppat.1009172</a>
  apa: Römhild, R., &#38; Andersson, D. I. (2021). Mechanisms and therapeutic potential
    of collateral sensitivity to antibiotics. <i>PLoS Pathogens</i>. Public Library
    of Science. <a href="https://doi.org/10.1371/journal.ppat.1009172">https://doi.org/10.1371/journal.ppat.1009172</a>
  chicago: Römhild, Roderich, and Dan I. Andersson. “Mechanisms and Therapeutic Potential
    of Collateral Sensitivity to Antibiotics.” <i>PLoS Pathogens</i>. Public Library
    of Science, 2021. <a href="https://doi.org/10.1371/journal.ppat.1009172">https://doi.org/10.1371/journal.ppat.1009172</a>.
  ieee: R. Römhild and D. I. Andersson, “Mechanisms and therapeutic potential of collateral
    sensitivity to antibiotics,” <i>PLoS Pathogens</i>, vol. 17, no. 1. Public Library
    of Science, 2021.
  ista: Römhild R, Andersson DI. 2021. Mechanisms and therapeutic potential of collateral
    sensitivity to antibiotics. PLoS Pathogens. 17(1), e1009172.
  mla: Römhild, Roderich, and Dan I. Andersson. “Mechanisms and Therapeutic Potential
    of Collateral Sensitivity to Antibiotics.” <i>PLoS Pathogens</i>, vol. 17, no.
    1, e1009172, Public Library of Science, 2021, doi:<a href="https://doi.org/10.1371/journal.ppat.1009172">10.1371/journal.ppat.1009172</a>.
  short: R. Römhild, D.I. Andersson, PLoS Pathogens 17 (2021).
date_created: 2021-01-31T23:01:21Z
date_published: 2021-01-14T00:00:00Z
date_updated: 2023-08-07T13:36:55Z
day: '14'
ddc:
- '570'
department:
- _id: CaGu
doi: 10.1371/journal.ppat.1009172
external_id:
  isi:
  - '000610190400007'
  pmid:
  - '33444399'
file:
- access_level: open_access
  checksum: d745d7f8fcbb9b95fea16a36f94dee31
  content_type: application/pdf
  creator: dernst
  date_created: 2021-02-03T12:13:03Z
  date_updated: 2021-02-03T12:13:03Z
  file_id: '9070'
  file_name: 2021_PlosPathogens_Roemhild.pdf
  file_size: 570066
  relation: main_file
  success: 1
file_date_updated: 2021-02-03T12:13:03Z
has_accepted_license: '1'
intvolume: '        17'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS Pathogens
publication_identifier:
  eissn:
  - '15537374'
  issn:
  - '15537366'
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanisms and therapeutic potential of collateral sensitivity to antibiotics
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 17
year: '2021'
...
---
_id: '9047'
abstract:
- lang: eng
  text: This work analyzes the latency of the simplified successive cancellation (SSC)
    decoding scheme for polar codes proposed by Alamdar-Yazdi and Kschischang. It
    is shown that, unlike conventional successive cancellation decoding, where latency
    is linear in the block length, the latency of SSC decoding is sublinear. More
    specifically, the latency of SSC decoding is O(N1−1/μ) , where N is the block
    length and μ is the scaling exponent of the channel, which captures the speed
    of convergence of the rate to capacity. Numerical results demonstrate the tightness
    of the bound and show that most of the latency reduction arises from the parallel
    decoding of subcodes of rate 0 or 1.
acknowledgement: M. Mondelli was partially supported by grants NSF DMS-1613091, CCF-1714305,
  IIS-1741162, and ONR N00014-18-1-2729. S. A. Hashemi is supported by a Postdoctoral
  Fellowship from the Natural Sciences and Engineering Research Council of Canada
  (NSERC) and by Huawei. The authors would like to thank the anonymous reviewers for
  their comments that helped improving the quality of the manuscript.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
- first_name: Seyyed Ali
  full_name: Hashemi, Seyyed Ali
  last_name: Hashemi
- first_name: John M.
  full_name: Cioffi, John M.
  last_name: Cioffi
- first_name: Andrea
  full_name: Goldsmith, Andrea
  last_name: Goldsmith
citation:
  ama: Mondelli M, Hashemi SA, Cioffi JM, Goldsmith A. Sublinear latency for simplified
    successive cancellation decoding of polar codes. <i>IEEE Transactions on Wireless
    Communications</i>. 2021;20(1):18-27. doi:<a href="https://doi.org/10.1109/TWC.2020.3022922">10.1109/TWC.2020.3022922</a>
  apa: Mondelli, M., Hashemi, S. A., Cioffi, J. M., &#38; Goldsmith, A. (2021). Sublinear
    latency for simplified successive cancellation decoding of polar codes. <i>IEEE
    Transactions on Wireless Communications</i>. IEEE. <a href="https://doi.org/10.1109/TWC.2020.3022922">https://doi.org/10.1109/TWC.2020.3022922</a>
  chicago: Mondelli, Marco, Seyyed Ali Hashemi, John M. Cioffi, and Andrea Goldsmith.
    “Sublinear Latency for Simplified Successive Cancellation Decoding of Polar Codes.”
    <i>IEEE Transactions on Wireless Communications</i>. IEEE, 2021. <a href="https://doi.org/10.1109/TWC.2020.3022922">https://doi.org/10.1109/TWC.2020.3022922</a>.
  ieee: M. Mondelli, S. A. Hashemi, J. M. Cioffi, and A. Goldsmith, “Sublinear latency
    for simplified successive cancellation decoding of polar codes,” <i>IEEE Transactions
    on Wireless Communications</i>, vol. 20, no. 1. IEEE, pp. 18–27, 2021.
  ista: Mondelli M, Hashemi SA, Cioffi JM, Goldsmith A. 2021. Sublinear latency for
    simplified successive cancellation decoding of polar codes. IEEE Transactions
    on Wireless Communications. 20(1), 18–27.
  mla: Mondelli, Marco, et al. “Sublinear Latency for Simplified Successive Cancellation
    Decoding of Polar Codes.” <i>IEEE Transactions on Wireless Communications</i>,
    vol. 20, no. 1, IEEE, 2021, pp. 18–27, doi:<a href="https://doi.org/10.1109/TWC.2020.3022922">10.1109/TWC.2020.3022922</a>.
  short: M. Mondelli, S.A. Hashemi, J.M. Cioffi, A. Goldsmith, IEEE Transactions on
    Wireless Communications 20 (2021) 18–27.
date_created: 2021-01-31T23:01:21Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2023-08-07T13:36:25Z
day: '01'
department:
- _id: MaMo
doi: 10.1109/TWC.2020.3022922
external_id:
  arxiv:
  - '1909.04892'
  isi:
  - '000607808800002'
intvolume: '        20'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1909.04892
month: '01'
oa: 1
oa_version: Preprint
page: 18-27
publication: IEEE Transactions on Wireless Communications
publication_identifier:
  eissn:
  - '15582248'
  issn:
  - '15361276'
publication_status: published
publisher: IEEE
quality_controlled: '1'
related_material:
  record:
  - id: '8536'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Sublinear latency for simplified successive cancellation decoding of polar
  codes
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 20
year: '2021'
...
---
_id: '9048'
abstract:
- lang: eng
  text: The analogy between an equilibrium partition function and the return probability
    in many-body unitary dynamics has led to the concept of dynamical quantum phase
    transition (DQPT). DQPTs are defined by nonanalyticities in the return amplitude
    and are present in many models. In some cases, DQPTs can be related to equilibrium
    concepts, such as order parameters, yet their universal description is an open
    question. In this Letter, we provide first steps toward a classification of DQPTs
    by using a matrix product state description of unitary dynamics in the thermodynamic
    limit. This allows us to distinguish the two limiting cases of “precession” and
    “entanglement” DQPTs, which are illustrated using an analytical description in
    the quantum Ising model. While precession DQPTs are characterized by a large entanglement
    gap and are semiclassical in their nature, entanglement DQPTs occur near avoided
    crossings in the entanglement spectrum and can be distinguished by a complex pattern
    of nonlocal correlations. We demonstrate the existence of precession and entanglement
    DQPTs beyond Ising models, discuss observables that can distinguish them, and
    relate their interplay to complex DQPT phenomenology.
acknowledgement: "S. D. N. acknowledges funding from the Institute of Science and
  Technology (IST) Austria and from the European Union’s Horizon 2020 Research and
  Innovation Programme under the Marie Skłodowska-Curie Grant Agreement No. 754411.
  A. M. and M. S. were supported by the European Research Council (ERC) under the
  European Union’s Horizon 2020 Research and\r\nInnovation Programme (Grant Agreement
  No. 850899)."
article_number: '040602'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Stefano
  full_name: De Nicola, Stefano
  id: 42832B76-F248-11E8-B48F-1D18A9856A87
  last_name: De Nicola
  orcid: 0000-0002-4842-6671
- first_name: Alexios
  full_name: Michailidis, Alexios
  id: 36EBAD38-F248-11E8-B48F-1D18A9856A87
  last_name: Michailidis
  orcid: 0000-0002-8443-1064
- first_name: Maksym
  full_name: Serbyn, Maksym
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
citation:
  ama: De Nicola S, Michailidis A, Serbyn M. Entanglement view of dynamical quantum
    phase transitions. <i>Physical Review Letters</i>. 2021;126(4). doi:<a href="https://doi.org/10.1103/physrevlett.126.040602">10.1103/physrevlett.126.040602</a>
  apa: De Nicola, S., Michailidis, A., &#38; Serbyn, M. (2021). Entanglement view
    of dynamical quantum phase transitions. <i>Physical Review Letters</i>. American
    Physical Society. <a href="https://doi.org/10.1103/physrevlett.126.040602">https://doi.org/10.1103/physrevlett.126.040602</a>
  chicago: De Nicola, Stefano, Alexios Michailidis, and Maksym Serbyn. “Entanglement
    View of Dynamical Quantum Phase Transitions.” <i>Physical Review Letters</i>.
    American Physical Society, 2021. <a href="https://doi.org/10.1103/physrevlett.126.040602">https://doi.org/10.1103/physrevlett.126.040602</a>.
  ieee: S. De Nicola, A. Michailidis, and M. Serbyn, “Entanglement view of dynamical
    quantum phase transitions,” <i>Physical Review Letters</i>, vol. 126, no. 4. American
    Physical Society, 2021.
  ista: De Nicola S, Michailidis A, Serbyn M. 2021. Entanglement view of dynamical
    quantum phase transitions. Physical Review Letters. 126(4), 040602.
  mla: De Nicola, Stefano, et al. “Entanglement View of Dynamical Quantum Phase Transitions.”
    <i>Physical Review Letters</i>, vol. 126, no. 4, 040602, American Physical Society,
    2021, doi:<a href="https://doi.org/10.1103/physrevlett.126.040602">10.1103/physrevlett.126.040602</a>.
  short: S. De Nicola, A. Michailidis, M. Serbyn, Physical Review Letters 126 (2021).
date_created: 2021-02-01T09:20:00Z
date_published: 2021-01-29T00:00:00Z
date_updated: 2023-09-05T12:08:58Z
day: '29'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.1103/physrevlett.126.040602
ec_funded: 1
external_id:
  arxiv:
  - '2008.04894'
  isi:
  - '000613148200001'
file:
- access_level: open_access
  checksum: d9acbc502390ed7a97e631d23ae19ecd
  content_type: application/pdf
  creator: dernst
  date_created: 2021-02-03T12:47:04Z
  date_updated: 2021-02-03T12:47:04Z
  file_id: '9074'
  file_name: 2021_PhysicalRevLett_DeNicola.pdf
  file_size: 398075
  relation: main_file
  success: 1
file_date_updated: 2021-02-03T12:47:04Z
has_accepted_license: '1'
intvolume: '       126'
isi: 1
issue: '4'
keyword:
- General Physics and Astronomy
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '850899'
  name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: Entanglement view of dynamical quantum phase transitions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 126
year: '2021'
...
---
_id: '9056'
abstract:
- lang: eng
  text: "In this thesis we study persistence of multi-covers of Euclidean balls and
    the geometric structures underlying their computation, in particular Delaunay
    mosaics and Voronoi tessellations. The k-fold cover for some discrete input point
    set consists of the space where at least k balls of radius r around the input
    points overlap. Persistence is a notion that captures, in some sense, the topology
    of the shape underlying the input. While persistence is usually computed for the
    union of balls, the k-fold cover is of interest as it captures local density,\r\nand
    thus might approximate the shape of the input better if the input data is noisy.
    To compute persistence of these k-fold covers, we need a discretization that is
    provided by higher-order Delaunay mosaics. We present and implement a simple and
    efficient algorithm for the computation of higher-order Delaunay mosaics, and
    use it to give experimental results for their combinatorial properties. The algorithm
    makes use of a new geometric structure, the rhomboid tiling. It contains the higher-order
    Delaunay mosaics as slices, and by introducing a filtration\r\nfunction on the
    tiling, we also obtain higher-order α-shapes as slices. These allow us to compute
    persistence of the multi-covers for varying radius r; the computation for varying
    k is less straight-foward and involves the rhomboid tiling directly. We apply
    our algorithms to experimental sphere packings to shed light on their structural
    properties. Finally, inspired by periodic structures in packings and materials,
    we propose and implement an algorithm for periodic Delaunay triangulations to
    be integrated into the Computational Geometry Algorithms Library (CGAL), and discuss
    the implications on persistence for periodic data sets."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Georg F
  full_name: Osang, Georg F
  id: 464B40D6-F248-11E8-B48F-1D18A9856A87
  last_name: Osang
  orcid: 0000-0002-8882-5116
citation:
  ama: Osang GF. Multi-cover persistence and Delaunay mosaics. 2021. doi:<a href="https://doi.org/10.15479/AT:ISTA:9056">10.15479/AT:ISTA:9056</a>
  apa: Osang, G. F. (2021). <i>Multi-cover persistence and Delaunay mosaics</i>. Institute
    of Science and Technology Austria, Klosterneuburg. <a href="https://doi.org/10.15479/AT:ISTA:9056">https://doi.org/10.15479/AT:ISTA:9056</a>
  chicago: Osang, Georg F. “Multi-Cover Persistence and Delaunay Mosaics.” Institute
    of Science and Technology Austria, 2021. <a href="https://doi.org/10.15479/AT:ISTA:9056">https://doi.org/10.15479/AT:ISTA:9056</a>.
  ieee: G. F. Osang, “Multi-cover persistence and Delaunay mosaics,” Institute of
    Science and Technology Austria, Klosterneuburg, 2021.
  ista: 'Osang GF. 2021. Multi-cover persistence and Delaunay mosaics. Klosterneuburg:
    Institute of Science and Technology Austria.'
  mla: Osang, Georg F. <i>Multi-Cover Persistence and Delaunay Mosaics</i>. Institute
    of Science and Technology Austria, 2021, doi:<a href="https://doi.org/10.15479/AT:ISTA:9056">10.15479/AT:ISTA:9056</a>.
  short: G.F. Osang, Multi-Cover Persistence and Delaunay Mosaics, Institute of Science
    and Technology Austria, 2021.
date_created: 2021-02-02T14:11:06Z
date_published: 2021-02-01T00:00:00Z
date_updated: 2023-09-07T13:29:01Z
day: '01'
ddc:
- '006'
- '514'
- '516'
degree_awarded: PhD
department:
- _id: HeEd
- _id: GradSch
doi: 10.15479/AT:ISTA:9056
file:
- access_level: closed
  checksum: bcf27986147cab0533b6abadd74e7629
  content_type: application/zip
  creator: patrickd
  date_created: 2021-02-02T14:09:25Z
  date_updated: 2021-02-03T10:37:28Z
  file_id: '9063'
  file_name: thesis_source.zip
  file_size: 13446994
  relation: source_file
- access_level: open_access
  checksum: 9cc8af266579a464385bbe2aff6af606
  content_type: application/pdf
  creator: patrickd
  date_created: 2021-02-02T14:09:18Z
  date_updated: 2021-02-02T14:09:18Z
  file_id: '9064'
  file_name: thesis_pdfA2b.pdf
  file_size: 5210329
  relation: main_file
  success: 1
file_date_updated: 2021-02-03T10:37:28Z
has_accepted_license: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: '134'
place: Klosterneuburg
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '187'
    relation: part_of_dissertation
    status: public
  - id: '8703'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
title: Multi-cover persistence and Delaunay mosaics
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2021'
...
---
_id: '9073'
abstract:
- lang: eng
  text: The sensory and cognitive abilities of the mammalian neocortex are underpinned
    by intricate columnar and laminar circuits formed from an array of diverse neuronal
    populations. One approach to determining how interactions between these circuit
    components give rise to complex behavior is to investigate the rules by which
    cortical circuits are formed and acquire functionality during development. This
    review summarizes recent research on the development of the neocortex, from genetic
    determination in neural stem cells through to the dynamic role that specific neuronal
    populations play in the earliest circuits of neocortex, and how they contribute
    to emergent function and cognition. While many of these endeavors take advantage
    of model systems, consideration will also be given to advances in our understanding
    of activity in nascent human circuits. Such cross-species perspective is imperative
    when investigating the mechanisms underlying the dysfunction of early neocortical
    circuits in neurodevelopmental disorders, so that one can identify targets amenable
    to therapeutic intervention.
acknowledgement: Work in the I.L.H.-O. laboratory was supported by European Research
  Council Grant ERC-2015-CoG 681577 and German Research Foundation Ha 4466/10-1, Ha4466/11-1,
  Ha4466/12-1, SPP 1665, and SFB 936B5. Work in the S.J.B.B. laboratory was supported
  by Biotechnology and Biological Sciences Research Council BB/P003796/1, Medical
  Research Council MR/K004387/1 and MR/T033320/1, Wellcome Trust 215199/Z/19/Z and
  102386/Z/13/Z, and John Fell Fund. Work in the S.H. laboratory was supported by
  European Research Council Grants ERC-2016-CoG 725780 LinPro and FWF SFB F78. This
  work was supported by National Institutes of Health Grant NIMH 1R01MH110553 to N.V.D.M.G.
  Work in the J.A.C. laboratory was supported by the Ludwig Family Foundation, Simons
  Foundation SFARI Research Award, and National Institutes of Health/National Institute
  of Mental Health R01 MH102365 and R01MH113852. The B.V. laboratory was supported
  by Whitehall Foundation 2017-12-73, National Science Foundation 1736028, National
  Institutes of Health, National Institute of General Medical Sciences R01GM134363-01,
  and Halıcıoğlu Data Science Institute Fellowship. This work was supported by the
  University of California San Diego School of Medicine.
article_processing_charge: No
article_type: original
author:
- first_name: Ileana L.
  full_name: Hanganu-Opatz, Ileana L.
  last_name: Hanganu-Opatz
- first_name: Simon J. B.
  full_name: Butt, Simon J. B.
  last_name: Butt
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
- first_name: Natalia V.
  full_name: De Marco García, Natalia V.
  last_name: De Marco García
- first_name: Jessica A.
  full_name: Cardin, Jessica A.
  last_name: Cardin
- first_name: Bradley
  full_name: Voytek, Bradley
  last_name: Voytek
- first_name: Alysson R.
  full_name: Muotri, Alysson R.
  last_name: Muotri
citation:
  ama: Hanganu-Opatz IL, Butt SJB, Hippenmeyer S, et al. The logic of developing neocortical
    circuits in health and disease. <i>The Journal of Neuroscience</i>. 2021;41(5):813-822.
    doi:<a href="https://doi.org/10.1523/jneurosci.1655-20.2020">10.1523/jneurosci.1655-20.2020</a>
  apa: Hanganu-Opatz, I. L., Butt, S. J. B., Hippenmeyer, S., De Marco García, N.
    V., Cardin, J. A., Voytek, B., &#38; Muotri, A. R. (2021). The logic of developing
    neocortical circuits in health and disease. <i>The Journal of Neuroscience</i>.
    Society for Neuroscience. <a href="https://doi.org/10.1523/jneurosci.1655-20.2020">https://doi.org/10.1523/jneurosci.1655-20.2020</a>
  chicago: Hanganu-Opatz, Ileana L., Simon J. B. Butt, Simon Hippenmeyer, Natalia
    V. De Marco García, Jessica A. Cardin, Bradley Voytek, and Alysson R. Muotri.
    “The Logic of Developing Neocortical Circuits in Health and Disease.” <i>The Journal
    of Neuroscience</i>. Society for Neuroscience, 2021. <a href="https://doi.org/10.1523/jneurosci.1655-20.2020">https://doi.org/10.1523/jneurosci.1655-20.2020</a>.
  ieee: I. L. Hanganu-Opatz <i>et al.</i>, “The logic of developing neocortical circuits
    in health and disease,” <i>The Journal of Neuroscience</i>, vol. 41, no. 5. Society
    for Neuroscience, pp. 813–822, 2021.
  ista: Hanganu-Opatz IL, Butt SJB, Hippenmeyer S, De Marco García NV, Cardin JA,
    Voytek B, Muotri AR. 2021. The logic of developing neocortical circuits in health
    and disease. The Journal of Neuroscience. 41(5), 813–822.
  mla: Hanganu-Opatz, Ileana L., et al. “The Logic of Developing Neocortical Circuits
    in Health and Disease.” <i>The Journal of Neuroscience</i>, vol. 41, no. 5, Society
    for Neuroscience, 2021, pp. 813–22, doi:<a href="https://doi.org/10.1523/jneurosci.1655-20.2020">10.1523/jneurosci.1655-20.2020</a>.
  short: I.L. Hanganu-Opatz, S.J.B. Butt, S. Hippenmeyer, N.V. De Marco García, J.A.
    Cardin, B. Voytek, A.R. Muotri, The Journal of Neuroscience 41 (2021) 813–822.
date_created: 2021-02-03T12:23:51Z
date_published: 2021-02-03T00:00:00Z
date_updated: 2023-09-05T14:03:17Z
day: '03'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1523/jneurosci.1655-20.2020
ec_funded: 1
external_id:
  isi:
  - '000616763400002'
  pmid:
  - '33431633'
file:
- access_level: open_access
  checksum: 578fd7ed1a0aef74bce61bea2d987b33
  content_type: application/pdf
  creator: dernst
  date_created: 2022-05-27T06:59:55Z
  date_updated: 2022-05-27T06:59:55Z
  file_id: '11414'
  file_name: 2021_JourNeuroscience_Hanganu.pdf
  file_size: 1031150
  relation: main_file
  success: 1
file_date_updated: 2022-05-27T06:59:55Z
has_accepted_license: '1'
intvolume: '        41'
isi: 1
issue: '5'
keyword:
- General Neuroscience
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 813-822
pmid: 1
project:
- _id: 260018B0-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '725780'
  name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
- _id: 059F6AB4-7A3F-11EA-A408-12923DDC885E
  grant_number: F07805
  name: Molecular Mechanisms of Neural Stem Cell Lineage Progression
publication: The Journal of Neuroscience
publication_identifier:
  eissn:
  - 1529-2401
  issn:
  - 0270-6474
publication_status: published
publisher: Society for Neuroscience
quality_controlled: '1'
scopus_import: '1'
status: public
title: The logic of developing neocortical circuits in health and disease
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 41
year: '2021'
...
---
_id: '9082'
abstract:
- lang: eng
  text: Acquired mutations are sufficiently frequent such that the genome of a single
    cell offers a record of its history of cell divisions. Among more common somatic
    genomic alterations are loss of heterozygosity (LOH). Large LOH events are potentially
    detectable in single cell RNA sequencing (scRNA-seq) datasets as tracts of monoallelic
    expression for constitutionally heterozygous single nucleotide variants (SNVs)
    located among contiguous genes. We identified runs of monoallelic expression,
    consistent with LOH, uniquely distributed throughout the genome in single cell
    brain cortex transcriptomes of F1 hybrids involving different inbred mouse strains.
    We then phylogenetically reconstructed single cell lineages and simultaneously
    identified cell types by corresponding gene expression patterns. Our results are
    consistent with progenitor cells giving rise to multiple cortical cell types through
    stereotyped expansion and distinct waves of neurogenesis. Compared to engineered
    recording systems, LOH events accumulate throughout the genome and across the
    lifetime of an organism, affording tremendous capacity for encoding lineage information
    and increasing resolution for later cell divisions. This approach can conceivably
    be computationally incorporated into scRNA-seq analysis and may be useful for
    organisms where genetic engineering is prohibitive, such as humans.
acknowledgement: "We thank Bill Bolosky, Microsoft Research, for earlier work showing
  proof of concept in TCGA\r\nbulk RNA-seq data. Supported by the Paul G. Allen Frontiers
  Group (University of Washington);\r\nNIH R00HG010152 (Dartmouth); and NÖ Forschung
  und Bildung n[f+b] life science call grant\r\n(C13-002) to SH, and the European
  Research Council (ERC) under the European Union’s\r\nHorizon 2020 research and innovation
  program 725780 LinPro to SH."
article_processing_charge: No
author:
- first_name: Donovan J.
  full_name: Anderson, Donovan J.
  last_name: Anderson
- first_name: Florian
  full_name: Pauler, Florian
  id: 48EA0138-F248-11E8-B48F-1D18A9856A87
  last_name: Pauler
- first_name: Aaron
  full_name: McKenna, Aaron
  last_name: McKenna
- first_name: Jay
  full_name: Shendure, Jay
  last_name: Shendure
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
- first_name: Marshall S.
  full_name: Horwitz, Marshall S.
  last_name: Horwitz
citation:
  ama: Anderson DJ, Pauler F, McKenna A, Shendure J, Hippenmeyer S, Horwitz MS. Simultaneous
    identification of brain cell type and lineage via single cell RNA sequencing.
    <i>bioRxiv</i>. doi:<a href="https://doi.org/10.1101/2020.12.31.425016">10.1101/2020.12.31.425016</a>
  apa: Anderson, D. J., Pauler, F., McKenna, A., Shendure, J., Hippenmeyer, S., &#38;
    Horwitz, M. S. (n.d.). Simultaneous identification of brain cell type and lineage
    via single cell RNA sequencing. <i>bioRxiv</i>. Cold Spring Harbor Laboratory.
    <a href="https://doi.org/10.1101/2020.12.31.425016">https://doi.org/10.1101/2020.12.31.425016</a>
  chicago: Anderson, Donovan J., Florian Pauler, Aaron McKenna, Jay Shendure, Simon
    Hippenmeyer, and Marshall S. Horwitz. “Simultaneous Identification of Brain Cell
    Type and Lineage via Single Cell RNA Sequencing.” <i>BioRxiv</i>. Cold Spring
    Harbor Laboratory, n.d. <a href="https://doi.org/10.1101/2020.12.31.425016">https://doi.org/10.1101/2020.12.31.425016</a>.
  ieee: D. J. Anderson, F. Pauler, A. McKenna, J. Shendure, S. Hippenmeyer, and M.
    S. Horwitz, “Simultaneous identification of brain cell type and lineage via single
    cell RNA sequencing,” <i>bioRxiv</i>. Cold Spring Harbor Laboratory.
  ista: Anderson DJ, Pauler F, McKenna A, Shendure J, Hippenmeyer S, Horwitz MS. Simultaneous
    identification of brain cell type and lineage via single cell RNA sequencing.
    bioRxiv, <a href="https://doi.org/10.1101/2020.12.31.425016">10.1101/2020.12.31.425016</a>.
  mla: Anderson, Donovan J., et al. “Simultaneous Identification of Brain Cell Type
    and Lineage via Single Cell RNA Sequencing.” <i>BioRxiv</i>, Cold Spring Harbor
    Laboratory, doi:<a href="https://doi.org/10.1101/2020.12.31.425016">10.1101/2020.12.31.425016</a>.
  short: D.J. Anderson, F. Pauler, A. McKenna, J. Shendure, S. Hippenmeyer, M.S. Horwitz,
    BioRxiv (n.d.).
date_created: 2021-02-04T07:23:23Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2021-02-04T07:29:53Z
day: '01'
department:
- _id: SiHi
doi: 10.1101/2020.12.31.425016
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2020.12.31.425016
month: '01'
oa: 1
oa_version: Preprint
project:
- _id: 260018B0-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '725780'
  name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
publication: bioRxiv
publication_status: submitted
publisher: Cold Spring Harbor Laboratory
status: public
title: Simultaneous identification of brain cell type and lineage via single cell
  RNA sequencing
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
