---
_id: '491'
abstract:
- lang: eng
text: In their search for antigens, lymphocytes continuously shuttle among blood
vessels, lymph vessels, and lymphatic tissues. Chemokines mediate entry of lymphocytes
into lymphatic tissues, and sphingosine 1-phosphate (S1P) promotes localization
of lymphocytes to the vasculature. Both signals are sensed through G protein-coupled
receptors (GPCRs). Most GPCRs undergo ligand-dependent homologous receptor desensitization,
a process that decreases their signaling output after previous exposure to high
ligand concentration. Such desensitization can explain why lymphocytes do not
take an intermediate position between two signals but rather oscillate between
them. The desensitization of S1P receptor 1 (S1PR1) is mediated by GPCR kinase
2 (GRK2). Deletion of GRK2 in lymphocytes compromises desensitization by high
vascular S1P concentrations, thereby reducing responsiveness to the chemokine
signal and trapping the cells in the vascular compartment. The desensitization
kinetics of S1PR1 allows lymphocytes to dynamically shuttle between vasculature
and lymphatic tissue, although the positional information in both compartments
is static.
article_number: pe43
author:
- first_name: Alexander
full_name: Eichner, Alexander
id: 4DFA52AE-F248-11E8-B48F-1D18A9856A87
last_name: Eichner
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
citation:
ama: Eichner A, Sixt MK. Setting the clock for recirculating lymphocytes. Science
Signaling. 2011;4(198). doi:10.1126/scisignal.2002617
apa: Eichner, A., & Sixt, M. K. (2011). Setting the clock for recirculating
lymphocytes. Science Signaling. American Association for the Advancement
of Science. https://doi.org/10.1126/scisignal.2002617
chicago: Eichner, Alexander, and Michael K Sixt. “Setting the Clock for Recirculating
Lymphocytes.” Science Signaling. American Association for the Advancement
of Science, 2011. https://doi.org/10.1126/scisignal.2002617.
ieee: A. Eichner and M. K. Sixt, “Setting the clock for recirculating lymphocytes,”
Science Signaling, vol. 4, no. 198. American Association for the Advancement
of Science, 2011.
ista: Eichner A, Sixt MK. 2011. Setting the clock for recirculating lymphocytes.
Science Signaling. 4(198), pe43.
mla: Eichner, Alexander, and Michael K. Sixt. “Setting the Clock for Recirculating
Lymphocytes.” Science Signaling, vol. 4, no. 198, pe43, American Association
for the Advancement of Science, 2011, doi:10.1126/scisignal.2002617.
short: A. Eichner, M.K. Sixt, Science Signaling 4 (2011).
date_created: 2018-12-11T11:46:46Z
date_published: 2011-11-08T00:00:00Z
date_updated: 2021-01-12T08:01:02Z
day: '08'
department:
- _id: MiSi
doi: 10.1126/scisignal.2002617
intvolume: ' 4'
issue: '198'
language:
- iso: eng
month: '11'
oa_version: None
publication: Science Signaling
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '7329'
quality_controlled: '1'
scopus_import: 1
status: public
title: Setting the clock for recirculating lymphocytes
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2011'
...
---
_id: '518'
abstract:
- lang: eng
text: Cancer stem cells or cancer initiating cells are believed to contribute to
cancer recurrence after therapy. MicroRNAs (miRNAs) are short RNA molecules with
fundamental roles in gene regulation. The role of miRNAs in cancer stem cells
is only poorly understood. Here, we report miRNA expression profiles of glioblastoma
stem cell-containing CD133 + cell populations. We find that miR-9, miR-9 * (referred
to as miR-9/9 *), miR-17 and miR-106b are highly abundant in CD133 + cells. Furthermore,
inhibition of miR-9/9 * or miR-17 leads to reduced neurosphere formation and stimulates
cell differentiation. Calmodulin-binding transcription activator 1 (CAMTA1) is
a putative transcription factor, which induces the expression of the anti-proliferative
cardiac hormone natriuretic peptide A (NPPA). We identify CAMTA1 as an miR-9/9
* and miR-17 target. CAMTA1 expression leads to reduced neurosphere formation
and tumour growth in nude mice, suggesting that CAMTA1 can function as tumour
suppressor. Consistently, CAMTA1 and NPPA expression correlate with patient survival.
Our findings could provide a basis for novel strategies of glioblastoma therapy.
article_processing_charge: No
article_type: original
author:
- first_name: Daniel
full_name: Schraivogel, Daniel
last_name: Schraivogel
- first_name: Lasse
full_name: Weinmann, Lasse
last_name: Weinmann
- first_name: Dagmar
full_name: Beier, Dagmar
last_name: Beier
- first_name: Ghazaleh
full_name: Tabatabai, Ghazaleh
last_name: Tabatabai
- first_name: Alexander
full_name: Eichner, Alexander
id: 4DFA52AE-F248-11E8-B48F-1D18A9856A87
last_name: Eichner
- first_name: Jia
full_name: Zhu, Jia
last_name: Zhu
- first_name: Martina
full_name: Anton, Martina
last_name: Anton
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
- first_name: Michael
full_name: Weller, Michael
last_name: Weller
- first_name: Christoph
full_name: Beier, Christoph
last_name: Beier
- first_name: Gunter
full_name: Meister, Gunter
last_name: Meister
citation:
ama: Schraivogel D, Weinmann L, Beier D, et al. CAMTA1 is a novel tumour suppressor
regulated by miR-9/9 * in glioblastoma stem cells. EMBO Journal. 2011;30(20):4309-4322.
doi:10.1038/emboj.2011.301
apa: Schraivogel, D., Weinmann, L., Beier, D., Tabatabai, G., Eichner, A., Zhu,
J., … Meister, G. (2011). CAMTA1 is a novel tumour suppressor regulated by miR-9/9
* in glioblastoma stem cells. EMBO Journal. Wiley-Blackwell. https://doi.org/10.1038/emboj.2011.301
chicago: Schraivogel, Daniel, Lasse Weinmann, Dagmar Beier, Ghazaleh Tabatabai,
Alexander Eichner, Jia Zhu, Martina Anton, et al. “CAMTA1 Is a Novel Tumour Suppressor
Regulated by MiR-9/9 * in Glioblastoma Stem Cells.” EMBO Journal. Wiley-Blackwell,
2011. https://doi.org/10.1038/emboj.2011.301.
ieee: D. Schraivogel et al., “CAMTA1 is a novel tumour suppressor regulated
by miR-9/9 * in glioblastoma stem cells,” EMBO Journal, vol. 30, no. 20.
Wiley-Blackwell, pp. 4309–4322, 2011.
ista: Schraivogel D, Weinmann L, Beier D, Tabatabai G, Eichner A, Zhu J, Anton M,
Sixt MK, Weller M, Beier C, Meister G. 2011. CAMTA1 is a novel tumour suppressor
regulated by miR-9/9 * in glioblastoma stem cells. EMBO Journal. 30(20), 4309–4322.
mla: Schraivogel, Daniel, et al. “CAMTA1 Is a Novel Tumour Suppressor Regulated
by MiR-9/9 * in Glioblastoma Stem Cells.” EMBO Journal, vol. 30, no. 20,
Wiley-Blackwell, 2011, pp. 4309–22, doi:10.1038/emboj.2011.301.
short: D. Schraivogel, L. Weinmann, D. Beier, G. Tabatabai, A. Eichner, J. Zhu,
M. Anton, M.K. Sixt, M. Weller, C. Beier, G. Meister, EMBO Journal 30 (2011) 4309–4322.
date_created: 2018-12-11T11:46:55Z
date_published: 2011-10-19T00:00:00Z
date_updated: 2021-01-12T08:01:19Z
day: '19'
department:
- _id: MiSi
doi: 10.1038/emboj.2011.301
external_id:
pmid:
- '21857646'
intvolume: ' 30'
issue: '20'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199389/
month: '10'
oa: 1
oa_version: Submitted Version
page: 4309 - 4322
pmid: 1
publication: EMBO Journal
publication_status: published
publisher: Wiley-Blackwell
publist_id: '7301'
quality_controlled: '1'
scopus_import: 1
status: public
title: CAMTA1 is a novel tumour suppressor regulated by miR-9/9 * in glioblastoma
stem cells
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 30
year: '2011'
...
---
_id: '531'
abstract:
- lang: eng
text: Software transactional memories (STM) are described in the literature with
assumptions of sequentially consistent program execution and atomicity of high
level operations like read, write, and abort. However, in a realistic setting,
processors use relaxed memory models to optimize hardware performance. Moreover,
the atomicity of operations depends on the underlying hardware. This paper presents
the first approach to verify STMs under relaxed memory models with atomicity of
32 bit loads and stores, and read-modify-write operations. We describe RML, a
simple language for expressing concurrent programs. We develop a semantics of
RML parametrized by a relaxed memory model. We then present our tool, FOIL, which
takes as input the RML description of an STM algorithm restricted to two threads
and two variables, and the description of a memory model, and automatically determines
the locations of fences, which if inserted, ensure the correctness of the restricted
STM algorithm under the given memory model. We use FOIL to verify DSTM, TL2, and
McRT STM under the memory models of sequential consistency, total store order,
partial store order, and relaxed memory order for two threads and two variables.
Finally, we extend the verification results for DSTM and TL2 to an arbitrary number
of threads and variables by manually proving that the structural properties of
STMs are satisfied at the hardware level of atomicity under the considered relaxed
memory models.
article_processing_charge: No
article_type: original
author:
- first_name: Rachid
full_name: Guerraoui, Rachid
last_name: Guerraoui
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Vasu
full_name: Singh, Vasu
id: 4DAE2708-F248-11E8-B48F-1D18A9856A87
last_name: Singh
citation:
ama: Guerraoui R, Henzinger TA, Singh V. Verification of STM on relaxed memory models.
Formal Methods in System Design. 2011;39(3):297-331. doi:10.1007/s10703-011-0131-3
apa: Guerraoui, R., Henzinger, T. A., & Singh, V. (2011). Verification of STM
on relaxed memory models. Formal Methods in System Design. Springer. https://doi.org/10.1007/s10703-011-0131-3
chicago: Guerraoui, Rachid, Thomas A Henzinger, and Vasu Singh. “Verification of
STM on Relaxed Memory Models.” Formal Methods in System Design. Springer,
2011. https://doi.org/10.1007/s10703-011-0131-3.
ieee: R. Guerraoui, T. A. Henzinger, and V. Singh, “Verification of STM on relaxed
memory models,” Formal Methods in System Design, vol. 39, no. 3. Springer,
pp. 297–331, 2011.
ista: Guerraoui R, Henzinger TA, Singh V. 2011. Verification of STM on relaxed memory
models. Formal Methods in System Design. 39(3), 297–331.
mla: Guerraoui, Rachid, et al. “Verification of STM on Relaxed Memory Models.” Formal
Methods in System Design, vol. 39, no. 3, Springer, 2011, pp. 297–331, doi:10.1007/s10703-011-0131-3.
short: R. Guerraoui, T.A. Henzinger, V. Singh, Formal Methods in System Design 39
(2011) 297–331.
date_created: 2018-12-11T11:47:00Z
date_published: 2011-12-01T00:00:00Z
date_updated: 2021-01-12T08:01:27Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1007/s10703-011-0131-3
intvolume: ' 39'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://infoscience.epfl.ch/record/178042/files/art3A10.10072Fs10703-011-0131-3.pdf
month: '12'
oa: 1
oa_version: Published Version
page: 297 - 331
publication: Formal Methods in System Design
publication_status: published
publisher: Springer
publist_id: '7288'
quality_controlled: '1'
scopus_import: 1
status: public
title: Verification of STM on relaxed memory models
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 39
year: '2011'
...
---
_id: '5379'
abstract:
- lang: eng
text: Computing the winning set for Büchi objectives in alternating games on graphs
is a central problem in computer aided verification with a large number of applications.
The long standing best known upper bound for solving the problem is ̃O(n·m), where
n is the number of vertices and m is the number of edges in the graph. We are
the first to break the ̃O(n·m) boundary by presenting a new technique that reduces
the running time to O(n2). This bound also leads to O(n2) time algorithms for
computing the set of almost-sure winning vertices for Büchi objectives (1) in
alternating games with probabilistic transitions (improving an earlier bound of
O(n·m)), (2) in concurrent graph games with constant actions (improving an earlier
bound of O(n3)), and (3) in Markov decision processes (improving for m > n4/3
an earlier bound of O(min(m1.5, m·n2/3)). We also show that the same technique
can be used to compute the maximal end-component decomposition of a graph in time
O(n2), which is an improvement over earlier bounds for m > n4/3. Finally, we show
how to maintain the winning set for Büchi objectives in alternating games under
a sequence of edge insertions or a sequence of edge deletions in O(n) amortized
time per operation. This is the first dynamic algorithm for this problem.
alternative_title:
- IST Austria Technical Report
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
citation:
ama: Chatterjee K, Henzinger MH. An O(N2) Time Algorithm for Alternating Büchi
Games. IST Austria; 2011. doi:10.15479/AT:IST-2011-0009
apa: Chatterjee, K., & Henzinger, M. H. (2011). An O(n2) time algorithm for
alternating Büchi games. IST Austria. https://doi.org/10.15479/AT:IST-2011-0009
chicago: Chatterjee, Krishnendu, and Monika H Henzinger. An O(N2) Time Algorithm
for Alternating Büchi Games. IST Austria, 2011. https://doi.org/10.15479/AT:IST-2011-0009.
ieee: K. Chatterjee and M. H. Henzinger, An O(n2) time algorithm for alternating
Büchi games. IST Austria, 2011.
ista: Chatterjee K, Henzinger MH. 2011. An O(n2) time algorithm for alternating
Büchi games, IST Austria, 20p.
mla: Chatterjee, Krishnendu, and Monika H. Henzinger. An O(N2) Time Algorithm
for Alternating Büchi Games. IST Austria, 2011, doi:10.15479/AT:IST-2011-0009.
short: K. Chatterjee, M.H. Henzinger, An O(N2) Time Algorithm for Alternating Büchi
Games, IST Austria, 2011.
date_created: 2018-12-12T11:38:59Z
date_published: 2011-07-11T00:00:00Z
date_updated: 2023-02-23T11:15:12Z
day: '11'
ddc:
- '000'
- '004'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2011-0009
file:
- access_level: open_access
checksum: 0b354264229045d982332fd2cb5b9a26
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:43Z
date_updated: 2020-07-14T12:46:39Z
file_id: '5504'
file_name: IST-2011-0009_IST-2011-0009.pdf
file_size: 388665
relation: main_file
file_date_updated: 2020-07-14T12:46:39Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '20'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '15'
related_material:
record:
- id: '3165'
relation: later_version
status: public
status: public
title: An O(n2) time algorithm for alternating Büchi games
type: technical_report
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2011'
...
---
_id: '5380'
abstract:
- lang: eng
text: 'We consider 2-player games played on a finite state space for an infinite
number of rounds. The games are concurrent: in each round, the two players (player
1 and player 2) choose their moves independently and simultaneously; the current
state and the two moves determine the successor state. We study concurrent games
with ω-regular winning conditions specified as parity objectives. We consider
the qualitative analysis problems: the computation of the almost-sure and limit-sure
winning set of states, where player 1 can ensure to win with probability 1 and
with probability arbitrarily close to 1, respectively. In general the almost-sure
and limit-sure winning strategies require both infinite-memory as well as infinite-precision
(to describe probabilities). We study the bounded-rationality problem for qualitative
analysis of concurrent parity games, where the strategy set for player 1 is restricted
to bounded-resource strategies. In terms of precision, strategies can be deterministic,
uniform, finite-precision or infinite-precision; and in terms of memory, strategies
can be memoryless, finite-memory or infinite-memory. We present a precise and
complete characterization of the qualitative winning sets for all combinations
of classes of strategies. In particular, we show that uniform memoryless strategies
are as powerful as finite-precision infinite-memory strategies, and infinite-precision
memoryless strategies are as powerful as infinite-precision finite-memory strategies. We
show that the winning sets can be computed in O(n2d+3) time, where n is the size
of the game structure and 2d is the number of priorities (or colors), and our
algorithms are symbolic. The membership problem of whether a state belongs to
a winning set can be decided in NP ∩ coNP. While this complexity is the same as
for the simpler class of turn-based parity games, where in each state only one
of the two players has a choice of moves, our algorithms,that are obtained by
characterization of the winning sets as μ-calculus formulas, are considerably
more involved than those for turn-based games.'
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
citation:
ama: Chatterjee K. Bounded Rationality in Concurrent Parity Games. IST Austria;
2011. doi:10.15479/AT:IST-2011-0008
apa: Chatterjee, K. (2011). Bounded rationality in concurrent parity games.
IST Austria. https://doi.org/10.15479/AT:IST-2011-0008
chicago: Chatterjee, Krishnendu. Bounded Rationality in Concurrent Parity Games.
IST Austria, 2011. https://doi.org/10.15479/AT:IST-2011-0008.
ieee: K. Chatterjee, Bounded rationality in concurrent parity games. IST
Austria, 2011.
ista: Chatterjee K. 2011. Bounded rationality in concurrent parity games, IST Austria,
53p.
mla: Chatterjee, Krishnendu. Bounded Rationality in Concurrent Parity Games.
IST Austria, 2011, doi:10.15479/AT:IST-2011-0008.
short: K. Chatterjee, Bounded Rationality in Concurrent Parity Games, IST Austria,
2011.
date_created: 2018-12-12T11:39:00Z
date_published: 2011-07-11T00:00:00Z
date_updated: 2023-02-23T11:22:53Z
day: '11'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2011-0008
file:
- access_level: open_access
checksum: 0fd38186409be819a911c4990fa79d1f
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:54:22Z
date_updated: 2020-07-14T12:46:39Z
file_id: '5544'
file_name: IST-2011-0008_IST-2011-0008.pdf
file_size: 500399
relation: main_file
file_date_updated: 2020-07-14T12:46:39Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '53'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '16'
related_material:
record:
- id: '3338'
relation: later_version
status: public
status: public
title: Bounded rationality in concurrent parity games
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '5381'
abstract:
- lang: eng
text: "In two-player finite-state stochastic games of partial obser- vation on graphs,
in every state of the graph, the players simultaneously choose an action, and
their joint actions determine a probability distri- bution over the successor
states. The game is played for infinitely many rounds and thus the players construct
an infinite path in the graph. We consider reachability objectives where the first
player tries to ensure a target state to be visited almost-surely (i.e., with
probability 1) or pos- itively (i.e., with positive probability), no matter the
strategy of the second player.\r\n\r\nWe classify such games according to the
information and to the power of randomization available to the players. On the
basis of information, the game can be one-sided with either (a) player 1, or (b)
player 2 having partial observation (and the other player has perfect observation),
or two- sided with (c) both players having partial observation. On the basis of
randomization, (a) the players may not be allowed to use randomization (pure strategies),
or (b) they may choose a probability distribution over actions but the actual
random choice is external and not visible to the player (actions invisible), or
(c) they may use full randomization.\r\n\r\nOur main results for pure strategies
are as follows: (1) For one-sided games with player 2 perfect observation we show
that (in contrast to full randomized strategies) belief-based (subset-construction
based) strate- gies are not sufficient, and present an exponential upper bound
on mem- ory both for almost-sure and positive winning strategies; we show that
the problem of deciding the existence of almost-sure and positive winning strategies
for player 1 is EXPTIME-complete and present symbolic algo- rithms that avoid
the explicit exponential construction. (2) For one-sided games with player 1 perfect
observation we show that non-elementary memory is both necessary and sufficient
for both almost-sure and posi- tive winning strategies. (3) We show that for the
general (two-sided) case finite-memory strategies are sufficient for both positive
and almost-sure winning, and at least non-elementary memory is required. We establish
the equivalence of the almost-sure winning problems for pure strategies and for
randomized strategies with actions invisible. Our equivalence re- sult exhibit
serious flaws in previous results in the literature: we show a non-elementary
memory lower bound for almost-sure winning whereas an exponential upper bound
was previously claimed."
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Laurent
full_name: Doyen, Laurent
last_name: Doyen
citation:
ama: 'Chatterjee K, Doyen L. Partial-Observation Stochastic Games: How to Win
When Belief Fails. IST Austria; 2011. doi:10.15479/AT:IST-2011-0007'
apa: 'Chatterjee, K., & Doyen, L. (2011). Partial-observation stochastic
games: How to win when belief fails. IST Austria. https://doi.org/10.15479/AT:IST-2011-0007'
chicago: 'Chatterjee, Krishnendu, and Laurent Doyen. Partial-Observation Stochastic
Games: How to Win When Belief Fails. IST Austria, 2011. https://doi.org/10.15479/AT:IST-2011-0007.'
ieee: 'K. Chatterjee and L. Doyen, Partial-observation stochastic games: How
to win when belief fails. IST Austria, 2011.'
ista: 'Chatterjee K, Doyen L. 2011. Partial-observation stochastic games: How to
win when belief fails, IST Austria, 43p.'
mla: 'Chatterjee, Krishnendu, and Laurent Doyen. Partial-Observation Stochastic
Games: How to Win When Belief Fails. IST Austria, 2011, doi:10.15479/AT:IST-2011-0007.'
short: 'K. Chatterjee, L. Doyen, Partial-Observation Stochastic Games: How to Win
When Belief Fails, IST Austria, 2011.'
date_created: 2018-12-12T11:39:00Z
date_published: 2011-07-05T00:00:00Z
date_updated: 2023-02-23T11:05:48Z
day: '05'
ddc:
- '000'
- '005'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2011-0007
file:
- access_level: open_access
checksum: 06bf6dfc97f6006e3fd0e9a3f31bc961
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:27Z
date_updated: 2020-07-14T12:46:39Z
file_id: '5488'
file_name: IST-2011-0007_IST-2011-0007.pdf
file_size: 574055
relation: main_file
file_date_updated: 2020-07-14T12:46:39Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '43'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '17'
related_material:
record:
- id: '1903'
relation: later_version
status: public
- id: '2211'
relation: later_version
status: public
- id: '2955'
relation: later_version
status: public
status: public
title: 'Partial-observation stochastic games: How to win when belief fails'
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '5382'
abstract:
- lang: eng
text: 'We consider two-player stochastic games played on a finite state space for
an infinite num- ber of rounds. The games are concurrent: in each round, the two
players (player 1 and player 2) choose their moves independently and simultaneously;
the current state and the two moves determine a probability distribution over
the successor states. We also consider the important special case of turn-based
stochastic games where players make moves in turns, rather than concurrently.
We study concurrent games with ω-regular winning conditions specified as parity
objectives. The value for player 1 for a parity objective is the maximal probability
with which the player can guarantee the satisfaction of the objective against
all strategies of the opponent. We study the problem of continuity and robustness
of the value function in concurrent and turn-based stochastic parity games with
respect to imprecision in the transition probabilities. We present quantitative
bounds on the difference of the value function (in terms of the imprecision of
the transition probabilities) and show the value continuity for structurally equivalent
concurrent games (two games are structurally equivalent if the support of the
transition func- tion is same and the probabilities differ). We also show robustness
of optimal strategies for structurally equivalent turn-based stochastic parity
games. Finally we show that the value continuity property breaks without the structurally
equivalent assumption (even for Markov chains) and show that our quantitative
bound is asymptotically optimal. Hence our results are tight (the assumption is
both necessary and sufficient) and optimal (our quantitative bound is asymptotically
optimal).'
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
citation:
ama: Chatterjee K. Robustness of Structurally Equivalent Concurrent Parity Games.
IST Austria; 2011. doi:10.15479/AT:IST-2011-0006
apa: Chatterjee, K. (2011). Robustness of structurally equivalent concurrent
parity games. IST Austria. https://doi.org/10.15479/AT:IST-2011-0006
chicago: Chatterjee, Krishnendu. Robustness of Structurally Equivalent Concurrent
Parity Games. IST Austria, 2011. https://doi.org/10.15479/AT:IST-2011-0006.
ieee: K. Chatterjee, Robustness of structurally equivalent concurrent parity
games. IST Austria, 2011.
ista: Chatterjee K. 2011. Robustness of structurally equivalent concurrent parity
games, IST Austria, 18p.
mla: Chatterjee, Krishnendu. Robustness of Structurally Equivalent Concurrent
Parity Games. IST Austria, 2011, doi:10.15479/AT:IST-2011-0006.
short: K. Chatterjee, Robustness of Structurally Equivalent Concurrent Parity Games,
IST Austria, 2011.
date_created: 2018-12-12T11:39:00Z
date_published: 2011-06-27T00:00:00Z
date_updated: 2023-02-23T11:23:01Z
day: '27'
ddc:
- '000'
- '005'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2011-0006
file:
- access_level: open_access
checksum: 1322b652d6ab07eb5248298a3f91c1cf
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:54:24Z
date_updated: 2020-07-14T12:46:40Z
file_id: '5546'
file_name: IST-2011-0006_IST-2011-0006.pdf
file_size: 335997
relation: main_file
file_date_updated: 2020-07-14T12:46:40Z
has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: '18'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '18'
related_material:
record:
- id: '3341'
relation: later_version
status: public
status: public
title: Robustness of structurally equivalent concurrent parity games
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '5383'
abstract:
- lang: eng
text: We present a new decidable logic called TREX for expressing constraints about
imperative tree data structures. In particular, TREX supports a transitive closure
operator that can express reachability constraints, which often appear in data
structure invariants. We show that our logic is closed under weakest precondition
computation, which enables its use for automated software verification. We further
show that satisfiability of formulas in TREX is decidable in NP. The low complexity
makes it an attractive alternative to more expensive logics such as monadic second-order
logic (MSOL) over trees, which have been traditionally used for reasoning about
tree data structures.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Thomas
full_name: Wies, Thomas
id: 447BFB88-F248-11E8-B48F-1D18A9856A87
last_name: Wies
- first_name: Marco
full_name: Muñiz, Marco
last_name: Muñiz
- first_name: Viktor
full_name: Kuncak, Viktor
last_name: Kuncak
citation:
ama: Wies T, Muñiz M, Kuncak V. On an Efficient Decision Procedure for Imperative
Tree Data Structures. IST Austria; 2011. doi:10.15479/AT:IST-2011-0005
apa: Wies, T., Muñiz, M., & Kuncak, V. (2011). On an efficient decision procedure
for imperative tree data structures. IST Austria. https://doi.org/10.15479/AT:IST-2011-0005
chicago: Wies, Thomas, Marco Muñiz, and Viktor Kuncak. On an Efficient Decision
Procedure for Imperative Tree Data Structures. IST Austria, 2011. https://doi.org/10.15479/AT:IST-2011-0005.
ieee: T. Wies, M. Muñiz, and V. Kuncak, On an efficient decision procedure for
imperative tree data structures. IST Austria, 2011.
ista: Wies T, Muñiz M, Kuncak V. 2011. On an efficient decision procedure for imperative
tree data structures, IST Austria, 25p.
mla: Wies, Thomas, et al. On an Efficient Decision Procedure for Imperative Tree
Data Structures. IST Austria, 2011, doi:10.15479/AT:IST-2011-0005.
short: T. Wies, M. Muñiz, V. Kuncak, On an Efficient Decision Procedure for Imperative
Tree Data Structures, IST Austria, 2011.
date_created: 2018-12-12T11:39:01Z
date_published: 2011-04-26T00:00:00Z
date_updated: 2023-02-23T11:22:16Z
day: '26'
ddc:
- '000'
- '006'
department:
- _id: ToHe
doi: 10.15479/AT:IST-2011-0005
file:
- access_level: open_access
checksum: b20029184c4a819c5f4466a4a3d238b5
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:01Z
date_updated: 2020-07-14T12:46:40Z
file_id: '5462'
file_name: IST-2011-0005_IST-2011-0005.pdf
file_size: 619053
relation: main_file
file_date_updated: 2020-07-14T12:46:40Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: '25'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '19'
related_material:
record:
- id: '3323'
relation: later_version
status: public
status: public
title: On an efficient decision procedure for imperative tree data structures
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '5384'
abstract:
- lang: eng
text: 'We consider probabilistic automata on infinite words with acceptance defined
by parity conditions. We consider three qualitative decision problems: (i) the
positive decision problem asks whether there is a word that is accepted with positive
probability; (ii) the almost decision problem asks whether there is a word that
is accepted with probability 1; and (iii) the limit decision problem asks whether
for every ε > 0 there is a word that is accepted with probability at least 1 −
ε. We unify and generalize several decidability results for probabilistic automata
over infinite words, and identify a robust (closed under union and intersection)
subclass of probabilistic automata for which all the qualitative decision problems
are decidable for parity conditions. We also show that if the input words are
restricted to lasso shape words, then the positive and almost problems are decidable
for all probabilistic automata with parity conditions.'
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Mathieu
full_name: Tracol, Mathieu
id: 3F54FA38-F248-11E8-B48F-1D18A9856A87
last_name: Tracol
citation:
ama: Chatterjee K, Tracol M. Decidable Problems for Probabilistic Automata on
Infinite Words. IST Austria; 2011. doi:10.15479/AT:IST-2011-0004
apa: Chatterjee, K., & Tracol, M. (2011). Decidable problems for probabilistic
automata on infinite words. IST Austria. https://doi.org/10.15479/AT:IST-2011-0004
chicago: Chatterjee, Krishnendu, and Mathieu Tracol. Decidable Problems for Probabilistic
Automata on Infinite Words. IST Austria, 2011. https://doi.org/10.15479/AT:IST-2011-0004.
ieee: K. Chatterjee and M. Tracol, Decidable problems for probabilistic automata
on infinite words. IST Austria, 2011.
ista: Chatterjee K, Tracol M. 2011. Decidable problems for probabilistic automata
on infinite words, IST Austria, 30p.
mla: Chatterjee, Krishnendu, and Mathieu Tracol. Decidable Problems for Probabilistic
Automata on Infinite Words. IST Austria, 2011, doi:10.15479/AT:IST-2011-0004.
short: K. Chatterjee, M. Tracol, Decidable Problems for Probabilistic Automata on
Infinite Words, IST Austria, 2011.
date_created: 2018-12-12T11:39:01Z
date_published: 2011-04-11T00:00:00Z
date_updated: 2023-02-23T11:05:53Z
day: '11'
ddc:
- '000'
- '005'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2011-0004
file:
- access_level: open_access
checksum: f5a0f664fadc335990f5fcf138df19f1
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:54:23Z
date_updated: 2020-07-14T12:46:40Z
file_id: '5545'
file_name: IST-2011-004_IST-2011-0004.pdf
file_size: 570827
relation: main_file
file_date_updated: 2020-07-14T12:46:40Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: '30'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '20'
related_material:
record:
- id: '2957'
relation: later_version
status: public
status: public
title: Decidable problems for probabilistic automata on infinite words
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '5385'
abstract:
- lang: eng
text: There is recently a significant effort to add quantitative objectives to formal
verification and synthesis. We introduce and investigate the extension of temporal
logics with quantitative atomic assertions, aiming for a general and flexible
framework for quantitative-oriented specifications. In the heart of quantitative
objectives lies the accumulation of values along a computation. It is either the
accumulated summation, as with the energy objectives, or the accumulated average,
as with the mean-payoff objectives. We investigate the extension of temporal logics
with the prefix-accumulation assertions Sum(v) ≥ c and Avg(v) ≥ c, where v is
a numeric variable of the system, c is a constant rational number, and Sum(v)
and Avg(v) denote the accumulated sum and average of the values of v from the
beginning of the computation up to the current point of time. We also allow the
path-accumulation assertions LimInfAvg(v) ≥ c and LimSupAvg(v) ≥ c, referring
to the average value along an entire computation. We study the border of decidability
for extensions of various temporal logics. In particular, we show that extending
the fragment of CTL that has only the EX, EF, AX, and AG temporal modalities by
prefix-accumulation assertions and extending LTL with path-accumulation assertions,
result in temporal logics whose model-checking problem is decidable. The extended
logics allow to significantly extend the currently known energy and mean-payoff
objectives. Moreover, the prefix-accumulation assertions may be refined with “controlled-accumulation”,
allowing, for example, to specify constraints on the average waiting time between
a request and a grant. On the negative side, we show that the fragment we point
to is, in a sense, the maximal logic whose extension with prefix-accumulation
assertions permits a decidable model-checking procedure. Extending a temporal
logic that has the EG or EU modalities, and in particular CTL and LTL, makes the
problem undecidable.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Udi
full_name: Boker, Udi
id: 31E297B6-F248-11E8-B48F-1D18A9856A87
last_name: Boker
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Orna
full_name: Kupferman, Orna
last_name: Kupferman
citation:
ama: Boker U, Chatterjee K, Henzinger TA, Kupferman O. Temporal Specifications
with Accumulative Values. IST Austria; 2011. doi:10.15479/AT:IST-2011-0003
apa: Boker, U., Chatterjee, K., Henzinger, T. A., & Kupferman, O. (2011). Temporal
specifications with accumulative values. IST Austria. https://doi.org/10.15479/AT:IST-2011-0003
chicago: Boker, Udi, Krishnendu Chatterjee, Thomas A Henzinger, and Orna Kupferman.
Temporal Specifications with Accumulative Values. IST Austria, 2011. https://doi.org/10.15479/AT:IST-2011-0003.
ieee: U. Boker, K. Chatterjee, T. A. Henzinger, and O. Kupferman, Temporal specifications
with accumulative values. IST Austria, 2011.
ista: Boker U, Chatterjee K, Henzinger TA, Kupferman O. 2011. Temporal specifications
with accumulative values, IST Austria, 14p.
mla: Boker, Udi, et al. Temporal Specifications with Accumulative Values.
IST Austria, 2011, doi:10.15479/AT:IST-2011-0003.
short: U. Boker, K. Chatterjee, T.A. Henzinger, O. Kupferman, Temporal Specifications
with Accumulative Values, IST Austria, 2011.
date_created: 2018-12-12T11:39:02Z
date_published: 2011-04-04T00:00:00Z
date_updated: 2023-02-23T11:23:41Z
day: '04'
ddc:
- '000'
- '004'
department:
- _id: ToHe
- _id: KrCh
doi: 10.15479/AT:IST-2011-0003
ec_funded: 1
file:
- access_level: open_access
checksum: 8491d0d48c4911620ecd5350b413c11e
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:00Z
date_updated: 2020-07-14T12:46:41Z
file_id: '5461'
file_name: IST-2011-0003_IST-2011-0003.pdf
file_size: 366281
relation: main_file
file_date_updated: 2020-07-14T12:46:41Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: '14'
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25EFB36C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '215543'
name: COMponent-Based Embedded Systems design Techniques
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25F1337C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '214373'
name: Design for Embedded Systems
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '21'
related_material:
record:
- id: '2038'
relation: later_version
status: public
- id: '3356'
relation: later_version
status: public
status: public
title: Temporal specifications with accumulative values
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '5386'
abstract:
- lang: eng
text: 'We introduce TopoCut: a new way to integrate knowledge about topological
properties (TPs) into random field image segmentation model. Instead of including
TPs as additional constraints during minimization of the energy function, we devise
an efficient algorithm for modifying the unary potentials such that the resulting
segmentation is guaranteed with the desired properties. Our method is more flexible
in the sense that it handles more topology constraints than previous methods,
which were only able to enforce pairwise or global connectivity. In particular,
our method is very fast, making it for the first time possible to enforce global
topological properties in practical image segmentation tasks.'
alternative_title:
- IST Austria Technical Report
author:
- first_name: Chao
full_name: Chen, Chao
id: 3E92416E-F248-11E8-B48F-1D18A9856A87
last_name: Chen
- first_name: Daniel
full_name: Freedman, Daniel
last_name: Freedman
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: Chen C, Freedman D, Lampert C. Enforcing Topological Constraints in Random
Field Image Segmentation. IST Austria; 2011. doi:10.15479/AT:IST-2011-0002
apa: Chen, C., Freedman, D., & Lampert, C. (2011). Enforcing topological
constraints in random field image segmentation. IST Austria. https://doi.org/10.15479/AT:IST-2011-0002
chicago: Chen, Chao, Daniel Freedman, and Christoph Lampert. Enforcing Topological
Constraints in Random Field Image Segmentation. IST Austria, 2011. https://doi.org/10.15479/AT:IST-2011-0002.
ieee: C. Chen, D. Freedman, and C. Lampert, Enforcing topological constraints
in random field image segmentation. IST Austria, 2011.
ista: Chen C, Freedman D, Lampert C. 2011. Enforcing topological constraints in
random field image segmentation, IST Austria, 69p.
mla: Chen, Chao, et al. Enforcing Topological Constraints in Random Field Image
Segmentation. IST Austria, 2011, doi:10.15479/AT:IST-2011-0002.
short: C. Chen, D. Freedman, C. Lampert, Enforcing Topological Constraints in Random
Field Image Segmentation, IST Austria, 2011.
date_created: 2018-12-12T11:39:02Z
date_published: 2011-03-28T00:00:00Z
date_updated: 2023-02-23T11:22:48Z
day: '28'
ddc:
- '000'
department:
- _id: ChLa
doi: 10.15479/AT:IST-2011-0002
file:
- access_level: open_access
checksum: ad64c2add5fe2ad10e9d5c669f3f9526
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:34Z
date_updated: 2020-07-14T12:46:41Z
file_id: '5495'
file_name: IST-2011-0002_IST-2011-0002.pdf
file_size: 26390601
relation: main_file
file_date_updated: 2020-07-14T12:46:41Z
has_accepted_license: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: '69'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '22'
related_material:
record:
- id: '3336'
relation: later_version
status: public
status: public
title: Enforcing topological constraints in random field image segmentation
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '5387'
abstract:
- lang: eng
text: We consider Markov Decision Processes (MDPs) with mean-payoff parity and energy
parity objectives. In system design, the parity objective is used to encode ω-regular
specifications, and the mean-payoff and energy objectives can be used to model
quantitative resource constraints. The energy condition re- quires that the resource
level never drops below 0, and the mean-payoff condi- tion requires that the limit-average
value of the resource consumption is within a threshold. While these two (energy
and mean-payoff) classical conditions are equivalent for two-player games, we
show that they differ for MDPs. We show that the problem of deciding whether a
state is almost-sure winning (i.e., winning with probability 1) in energy parity
MDPs is in NP ∩ coNP, while for mean- payoff parity MDPs, the problem is solvable
in polynomial time, improving a recent PSPACE bound.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Laurent
full_name: Doyen, Laurent
last_name: Doyen
citation:
ama: Chatterjee K, Doyen L. Energy and Mean-Payoff Parity Markov Decision Processes.
IST Austria; 2011. doi:10.15479/AT:IST-2011-0001
apa: Chatterjee, K., & Doyen, L. (2011). Energy and mean-payoff parity Markov
decision processes. IST Austria. https://doi.org/10.15479/AT:IST-2011-0001
chicago: Chatterjee, Krishnendu, and Laurent Doyen. Energy and Mean-Payoff Parity
Markov Decision Processes. IST Austria, 2011. https://doi.org/10.15479/AT:IST-2011-0001.
ieee: K. Chatterjee and L. Doyen, Energy and mean-payoff parity Markov decision
processes. IST Austria, 2011.
ista: Chatterjee K, Doyen L. 2011. Energy and mean-payoff parity Markov decision
processes, IST Austria, 20p.
mla: Chatterjee, Krishnendu, and Laurent Doyen. Energy and Mean-Payoff Parity
Markov Decision Processes. IST Austria, 2011, doi:10.15479/AT:IST-2011-0001.
short: K. Chatterjee, L. Doyen, Energy and Mean-Payoff Parity Markov Decision Processes,
IST Austria, 2011.
date_created: 2018-12-12T11:39:02Z
date_published: 2011-02-16T00:00:00Z
date_updated: 2023-02-23T11:23:11Z
day: '16'
ddc:
- '000'
- '005'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2011-0001
file:
- access_level: open_access
checksum: 824d6c70e6d3feb3e836b009e0b3cf73
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:52:57Z
date_updated: 2020-07-14T12:46:41Z
file_id: '5458'
file_name: IST-2011-0001_IST-2011-0001.pdf
file_size: 329976
relation: main_file
file_date_updated: 2020-07-14T12:46:41Z
has_accepted_license: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: '20'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '23'
related_material:
record:
- id: '3345'
relation: later_version
status: public
status: public
title: Energy and mean-payoff parity Markov decision processes
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '6496'
abstract:
- lang: eng
text: We report the switching behavior of the full bacterial flagellum system that
includes the filament and the motor in wild-type Escherichia coli cells. In sorting
the motor behavior by the clockwise bias, we find that the distributions of the
clockwise (CW) and counterclockwise (CCW) intervals are either exponential or
nonexponential with long tails. At low bias, CW intervals are exponentially distributed
and CCW intervals exhibit long tails. At intermediate CW bias (0.5) both CW and
CCW intervals are mainly exponentially distributed. A simple model suggests that
these two distinct switching behaviors are governed by the presence of signaling
noise within the chemotaxis network. Low noise yields exponentially distributed
intervals, whereas large noise yields nonexponential behavior with long tails.
These drastically different motor statistics may play a role in optimizing bacterial
behavior for a wide range of environmental conditions.
article_processing_charge: No
author:
- first_name: Heungwon
full_name: Park, Heungwon
last_name: Park
- first_name: Panos
full_name: Oikonomou, Panos
last_name: Oikonomou
- first_name: Calin C
full_name: Guet, Calin C
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
- first_name: Philippe
full_name: Cluzel, Philippe
last_name: Cluzel
citation:
ama: Park H, Oikonomou P, Guet CC, Cluzel P. Noise underlies switching behavior
of the bacterial flagellum. Biophysical Journal. 2011;101(10):2336-2340.
doi:10.1016/j.bpj.2011.09.040
apa: Park, H., Oikonomou, P., Guet, C. C., & Cluzel, P. (2011). Noise underlies
switching behavior of the bacterial flagellum. Biophysical Journal. Elsevier.
https://doi.org/10.1016/j.bpj.2011.09.040
chicago: Park, Heungwon, Panos Oikonomou, Calin C Guet, and Philippe Cluzel. “Noise
Underlies Switching Behavior of the Bacterial Flagellum.” Biophysical Journal.
Elsevier, 2011. https://doi.org/10.1016/j.bpj.2011.09.040.
ieee: H. Park, P. Oikonomou, C. C. Guet, and P. Cluzel, “Noise underlies switching
behavior of the bacterial flagellum,” Biophysical Journal, vol. 101, no.
10. Elsevier, pp. 2336–2340, 2011.
ista: Park H, Oikonomou P, Guet CC, Cluzel P. 2011. Noise underlies switching behavior
of the bacterial flagellum. Biophysical Journal. 101(10), 2336–2340.
mla: Park, Heungwon, et al. “Noise Underlies Switching Behavior of the Bacterial
Flagellum.” Biophysical Journal, vol. 101, no. 10, Elsevier, 2011, pp.
2336–40, doi:10.1016/j.bpj.2011.09.040.
short: H. Park, P. Oikonomou, C.C. Guet, P. Cluzel, Biophysical Journal 101 (2011)
2336–2340.
date_created: 2019-05-28T11:54:29Z
date_published: 2011-11-16T00:00:00Z
date_updated: 2021-04-16T11:54:49Z
day: '16'
department:
- _id: CaGu
doi: 10.1016/j.bpj.2011.09.040
external_id:
pmid:
- '22098731'
intvolume: ' 101'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218319/
month: '11'
oa: 1
oa_version: Published Version
page: 2336-2340
pmid: 1
publication: Biophysical Journal
publication_identifier:
issn:
- 0006-3495
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Noise underlies switching behavior of the bacterial flagellum
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 101
year: '2011'
...
---
_id: '9483'
abstract:
- lang: eng
text: Imprinted genes are expressed primarily or exclusively from either the maternal
or paternal allele, a phenomenon that occurs in flowering plants and mammals.
Flowering plant imprinted gene expression has been described primarily in endosperm,
a terminal nutritive tissue consumed by the embryo during seed development or
after germination. Imprinted expression in Arabidopsis thaliana endosperm is orchestrated
by differences in cytosine DNA methylation between the paternal and maternal genomes
as well as by Polycomb group proteins. Currently, only 11 imprinted A. thaliana
genes are known. Here, we use extensive sequencing of cDNA libraries to identify
9 paternally expressed and 34 maternally expressed imprinted genes in A. thaliana
endosperm that are regulated by the DNA-demethylating glycosylase DEMETER, the
DNA methyltransferase MET1, and/or the core Polycomb group protein FIE. These
genes encode transcription factors, proteins involved in hormone signaling, components
of the ubiquitin protein degradation pathway, regulators of histone and DNA methylation,
and small RNA pathway proteins. We also identify maternally expressed genes that
may be regulated by unknown mechanisms or deposited from maternal tissues. We
did not detect any imprinted genes in the embryo. Our results show that imprinted
gene expression is an extensive mechanistically complex phenomenon that likely
affects multiple aspects of seed development.
article_processing_charge: No
article_type: original
author:
- first_name: Tzung-Fu
full_name: Hsieh, Tzung-Fu
last_name: Hsieh
- first_name: Juhyun
full_name: Shin, Juhyun
last_name: Shin
- first_name: Rie
full_name: Uzawa, Rie
last_name: Uzawa
- first_name: Pedro
full_name: Silva, Pedro
last_name: Silva
- first_name: Stephanie
full_name: Cohen, Stephanie
last_name: Cohen
- first_name: Matthew J.
full_name: Bauer, Matthew J.
last_name: Bauer
- first_name: Meryl
full_name: Hashimoto, Meryl
last_name: Hashimoto
- first_name: Ryan C.
full_name: Kirkbride, Ryan C.
last_name: Kirkbride
- first_name: John J.
full_name: Harada, John J.
last_name: Harada
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
- first_name: Robert L.
full_name: Fischer, Robert L.
last_name: Fischer
citation:
ama: Hsieh T-F, Shin J, Uzawa R, et al. Regulation of imprinted gene expression
in Arabidopsis endosperm. Proceedings of the National Academy of Sciences.
2011;108(5):1755-1762. doi:10.1073/pnas.1019273108
apa: Hsieh, T.-F., Shin, J., Uzawa, R., Silva, P., Cohen, S., Bauer, M. J., … Fischer,
R. L. (2011). Regulation of imprinted gene expression in Arabidopsis endosperm.
Proceedings of the National Academy of Sciences. National Academy of Sciences.
https://doi.org/10.1073/pnas.1019273108
chicago: Hsieh, Tzung-Fu, Juhyun Shin, Rie Uzawa, Pedro Silva, Stephanie Cohen,
Matthew J. Bauer, Meryl Hashimoto, et al. “Regulation of Imprinted Gene Expression
in Arabidopsis Endosperm.” Proceedings of the National Academy of Sciences.
National Academy of Sciences, 2011. https://doi.org/10.1073/pnas.1019273108.
ieee: T.-F. Hsieh et al., “Regulation of imprinted gene expression in Arabidopsis
endosperm,” Proceedings of the National Academy of Sciences, vol. 108,
no. 5. National Academy of Sciences, pp. 1755–1762, 2011.
ista: Hsieh T-F, Shin J, Uzawa R, Silva P, Cohen S, Bauer MJ, Hashimoto M, Kirkbride
RC, Harada JJ, Zilberman D, Fischer RL. 2011. Regulation of imprinted gene expression
in Arabidopsis endosperm. Proceedings of the National Academy of Sciences. 108(5),
1755–1762.
mla: Hsieh, Tzung-Fu, et al. “Regulation of Imprinted Gene Expression in Arabidopsis
Endosperm.” Proceedings of the National Academy of Sciences, vol. 108,
no. 5, National Academy of Sciences, 2011, pp. 1755–62, doi:10.1073/pnas.1019273108.
short: T.-F. Hsieh, J. Shin, R. Uzawa, P. Silva, S. Cohen, M.J. Bauer, M. Hashimoto,
R.C. Kirkbride, J.J. Harada, D. Zilberman, R.L. Fischer, Proceedings of the National
Academy of Sciences 108 (2011) 1755–1762.
date_created: 2021-06-07T07:40:38Z
date_published: 2011-02-01T00:00:00Z
date_updated: 2021-12-14T08:33:49Z
day: '01'
department:
- _id: DaZi
doi: 10.1073/pnas.1019273108
extern: '1'
external_id:
pmid:
- '21257907'
intvolume: ' 108'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1073/pnas.1019273108
month: '02'
oa: 1
oa_version: Published Version
page: 1755-1762
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
eissn:
- 1091-6490
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Regulation of imprinted gene expression in Arabidopsis endosperm
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 108
year: '2011'
...
---
_id: '9522'
abstract:
- lang: eng
text: Little is known about chromatin remodeling events immediately after fertilization.
A recent report by Autran et al. (2011) in Cell now shows that chromatin regulatory
pathways that silence transposable elements are responsible for global delayed
activation of gene expression in the early Arabidopsis embryo.
article_processing_charge: No
author:
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
citation:
ama: Zilberman D. Balancing Parental Contributions in Plant Embryonic Gene Activation.
Vol 20. Elsevier; 2011:735-736. doi:10.1016/j.devcel.2011.05.018
apa: Zilberman, D. (2011). Balancing parental contributions in plant embryonic
gene activation. Developmental Cell (Vol. 20, pp. 735–736). Elsevier.
https://doi.org/10.1016/j.devcel.2011.05.018
chicago: Zilberman, Daniel. Balancing Parental Contributions in Plant Embryonic
Gene Activation. Developmental Cell. Vol. 20. Elsevier, 2011. https://doi.org/10.1016/j.devcel.2011.05.018.
ieee: D. Zilberman, Balancing parental contributions in plant embryonic gene
activation, vol. 20, no. 6. Elsevier, 2011, pp. 735–736.
ista: Zilberman D. 2011. Balancing parental contributions in plant embryonic gene
activation, Elsevier,p.
mla: Zilberman, Daniel. “Balancing Parental Contributions in Plant Embryonic Gene
Activation.” Developmental Cell, vol. 20, no. 6, Elsevier, 2011, pp. 735–36,
doi:10.1016/j.devcel.2011.05.018.
short: D. Zilberman, Balancing Parental Contributions in Plant Embryonic Gene Activation,
Elsevier, 2011.
date_created: 2021-06-08T06:23:39Z
date_published: 2011-06-14T00:00:00Z
date_updated: 2021-12-14T08:34:37Z
day: '14'
department:
- _id: DaZi
doi: 10.1016/j.devcel.2011.05.018
extern: '1'
external_id:
pmid:
- '21664571'
intvolume: ' 20'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.devcel.2011.05.018
month: '06'
oa: 1
oa_version: Published Version
page: 735-736
pmid: 1
publication: Developmental Cell
publication_identifier:
eissn:
- 1878-1551
issn:
- 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Balancing parental contributions in plant embryonic gene activation
type: other_academic_publication
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 20
year: '2011'
...
---
_id: '9648'
abstract:
- lang: eng
text: In this paper, we establish a correspondence between the incremental algorithm
for computing AT-models [8,9] and the one for computing persistent homology [6,14,15].
We also present a decremental algorithm for computing AT-models that allows to
extend the persistence computation to a wider setting. Finally, we show how to
combine incremental and decremental techniques for persistent homology computation.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Rocio
full_name: Gonzalez-Diaz, Rocio
last_name: Gonzalez-Diaz
- first_name: Adrian
full_name: Ion, Adrian
id: 29F89302-F248-11E8-B48F-1D18A9856A87
last_name: Ion
- first_name: Maria Jose
full_name: Jimenez, Maria Jose
last_name: Jimenez
- first_name: Regina
full_name: Poyatos, Regina
last_name: Poyatos
citation:
ama: 'Gonzalez-Diaz R, Ion A, Jimenez MJ, Poyatos R. Incremental-decremental algorithm
for computing AT-models and persistent homology. In: Computer Analysis of Images
and Patterns. Vol 6854. Springer Nature; 2011:286-293. doi:10.1007/978-3-642-23672-3_35'
apa: 'Gonzalez-Diaz, R., Ion, A., Jimenez, M. J., & Poyatos, R. (2011). Incremental-decremental
algorithm for computing AT-models and persistent homology. In Computer Analysis
of Images and Patterns (Vol. 6854, pp. 286–293). Seville, Spain: Springer
Nature. https://doi.org/10.1007/978-3-642-23672-3_35'
chicago: Gonzalez-Diaz, Rocio, Adrian Ion, Maria Jose Jimenez, and Regina Poyatos.
“Incremental-Decremental Algorithm for Computing AT-Models and Persistent Homology.”
In Computer Analysis of Images and Patterns, 6854:286–93. Springer Nature,
2011. https://doi.org/10.1007/978-3-642-23672-3_35.
ieee: R. Gonzalez-Diaz, A. Ion, M. J. Jimenez, and R. Poyatos, “Incremental-decremental
algorithm for computing AT-models and persistent homology,” in Computer Analysis
of Images and Patterns, Seville, Spain, 2011, vol. 6854, pp. 286–293.
ista: 'Gonzalez-Diaz R, Ion A, Jimenez MJ, Poyatos R. 2011. Incremental-decremental
algorithm for computing AT-models and persistent homology. Computer Analysis of
Images and Patterns. CAIP: International Conference on Computer Analysis of Images
and Patterns, LNCS, vol. 6854, 286–293.'
mla: Gonzalez-Diaz, Rocio, et al. “Incremental-Decremental Algorithm for Computing
AT-Models and Persistent Homology.” Computer Analysis of Images and Patterns,
vol. 6854, Springer Nature, 2011, pp. 286–93, doi:10.1007/978-3-642-23672-3_35.
short: R. Gonzalez-Diaz, A. Ion, M.J. Jimenez, R. Poyatos, in:, Computer Analysis
of Images and Patterns, Springer Nature, 2011, pp. 286–293.
conference:
end_date: 2011-08-31
location: Seville, Spain
name: 'CAIP: International Conference on Computer Analysis of Images and Patterns'
start_date: 2011-08-29
date_created: 2021-07-11T22:01:19Z
date_published: 2011-08-01T00:00:00Z
date_updated: 2021-08-12T13:53:17Z
day: '01'
department:
- _id: HeEd
doi: 10.1007/978-3-642-23672-3_35
intvolume: ' 6854'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://hdl.handle.net/11441/30766
month: '08'
oa: 1
oa_version: Published Version
page: 286-293
publication: Computer Analysis of Images and Patterns
publication_identifier:
eissn:
- '16113349'
isbn:
- '9783642236716'
issn:
- '03029743'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Incremental-decremental algorithm for computing AT-models and persistent homology
type: conference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
volume: 6854
year: '2011'
...
---
_id: '9762'
abstract:
- lang: eng
text: Defining population structure and genetic diversity levels is of the utmost
importance for developing efficient conservation strategies. Overfishing has caused
mean annual catches of the European spiny lobster (Palinurus elephas) to decrease
alarmingly along its distribution area. In this context, there is a need for comprehensive
studies to evaluate the genetic health of the exploited populations. The present
work is based on a set of 10 nuclear markers amplified in 331 individuals from
10 different localities covering most of P. elephas distribution area. Samples
from Atlantic and Mediterranean basins showed small but significant differences,
indicating that P. elephas populations do not behave as a single panmictic unit
but form two partially-overlapping groups. Despite intense overfishing, our dataset
did not recover a recent bottleneck signal, and showed a large and stable historical
effective size instead. This result could be accounted for by specific life history
traits (reproduction and longevity) and the limitations of molecular markers in
covering very recent timescales for non temporal samples. Our study emphasizes
the necessity of integrating information on effective population sizes and life
history parameters when evaluating population connectivity levels from genetic
data.
article_processing_charge: No
author:
- first_name: Ferran
full_name: Palero, Ferran
id: 3F0E2A22-F248-11E8-B48F-1D18A9856A87
last_name: Palero
orcid: 0000-0002-0343-8329
- first_name: Pere
full_name: Abello, Pere
last_name: Abello
- first_name: Enrique
full_name: Macpherson, Enrique
last_name: Macpherson
- first_name: Mark
full_name: Beaumont, Mark
last_name: Beaumont
- first_name: Marta
full_name: Pascual, Marta
last_name: Pascual
citation:
ama: 'Palero F, Abello P, Macpherson E, Beaumont M, Pascual M. Data from: Effect
of oceanographic barriers and overfishing on the population genetic structure
of the European spiny lobster (Palinurus elephas). 2011. doi:10.5061/dryad.299h8'
apa: 'Palero, F., Abello, P., Macpherson, E., Beaumont, M., & Pascual, M. (2011).
Data from: Effect of oceanographic barriers and overfishing on the population
genetic structure of the European spiny lobster (Palinurus elephas). IST Austria.
https://doi.org/10.5061/dryad.299h8'
chicago: 'Palero, Ferran, Pere Abello, Enrique Macpherson, Mark Beaumont, and Marta
Pascual. “Data from: Effect of Oceanographic Barriers and Overfishing on the Population
Genetic Structure of the European Spiny Lobster (Palinurus Elephas).” IST Austria,
2011. https://doi.org/10.5061/dryad.299h8.'
ieee: 'F. Palero, P. Abello, E. Macpherson, M. Beaumont, and M. Pascual, “Data from:
Effect of oceanographic barriers and overfishing on the population genetic structure
of the European spiny lobster (Palinurus elephas).” IST Austria, 2011.'
ista: 'Palero F, Abello P, Macpherson E, Beaumont M, Pascual M. 2011. Data from:
Effect of oceanographic barriers and overfishing on the population genetic structure
of the European spiny lobster (Palinurus elephas), IST Austria, 10.5061/dryad.299h8.'
mla: 'Palero, Ferran, et al. Data from: Effect of Oceanographic Barriers and
Overfishing on the Population Genetic Structure of the European Spiny Lobster
(Palinurus Elephas). IST Austria, 2011, doi:10.5061/dryad.299h8.'
short: F. Palero, P. Abello, E. Macpherson, M. Beaumont, M. Pascual, (2011).
date_created: 2021-08-02T07:11:19Z
date_published: 2011-05-12T00:00:00Z
date_updated: 2023-02-23T11:25:25Z
day: '12'
department:
- _id: NiBa
doi: 10.5061/dryad.299h8
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.299h8
month: '05'
oa: 1
oa_version: Published Version
publisher: IST Austria
related_material:
record:
- id: '3395'
relation: used_in_publication
status: public
status: public
title: 'Data from: Effect of oceanographic barriers and overfishing on the population
genetic structure of the European spiny lobster (Palinurus elephas)'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2011'
...
---
_id: '9943'
abstract:
- lang: eng
text: Segmentation is the process of partitioning digital images into meaningful
regions. The analysis of biological high content images often requires segmentation
as a first step. We propose ilastik as an easy-to-use tool which allows the user
without expertise in image processing to perform segmentation and classification
in a unified way. ilastik learns from labels provided by the user through a convenient
mouse interface. Based on these labels, ilastik infers a problem specific segmentation.
A random forest classifier is used in the learning step, in which each pixel's
neighborhood is characterized by a set of generic (nonlinear) features. ilastik
supports up to three spatial plus one spectral dimension and makes use of all
dimensions in the feature calculation. ilastik provides realtime feedback that
enables the user to interactively refine the segmentation result and hence further
fine-tune the classifier. An uncertainty measure guides the user to ambiguous
regions in the images. Real time performance is achieved by multi-threading which
fully exploits the capabilities of modern multi-core machines. Once a classifier
has been trained on a set of representative images, it can be exported and used
to automatically process a very large number of images (e.g. using the CellProfiler
pipeline). ilastik is an open source project and released under the BSD license
at www.ilastik.org.
article_processing_charge: No
author:
- first_name: Christoph M
full_name: Sommer, Christoph M
id: 4DF26D8C-F248-11E8-B48F-1D18A9856A87
last_name: Sommer
orcid: 0000-0003-1216-9105
- first_name: Christoph
full_name: Straehle, Christoph
last_name: Straehle
- first_name: Ullrich
full_name: Köthe, Ullrich
last_name: Köthe
- first_name: Fred A.
full_name: Hamprecht, Fred A.
last_name: Hamprecht
citation:
ama: 'Sommer CM, Straehle C, Köthe U, Hamprecht FA. Ilastik: Interactive learning
and segmentation toolkit. In: 2011 IEEE International Symposium on Biomedical
Imaging: From Nano to Micro. Institute of Electrical and Electronics Engineers;
2011. doi:10.1109/isbi.2011.5872394'
apa: 'Sommer, C. M., Straehle, C., Köthe, U., & Hamprecht, F. A. (2011). Ilastik:
Interactive learning and segmentation toolkit. In 2011 IEEE International Symposium
on Biomedical Imaging: from Nano to Micro. Chicago, Illinois, USA: Institute
of Electrical and Electronics Engineers. https://doi.org/10.1109/isbi.2011.5872394'
chicago: 'Sommer, Christoph M, Christoph Straehle, Ullrich Köthe, and Fred A. Hamprecht.
“Ilastik: Interactive Learning and Segmentation Toolkit.” In 2011 IEEE International
Symposium on Biomedical Imaging: From Nano to Micro. Institute of Electrical
and Electronics Engineers, 2011. https://doi.org/10.1109/isbi.2011.5872394.'
ieee: 'C. M. Sommer, C. Straehle, U. Köthe, and F. A. Hamprecht, “Ilastik: Interactive
learning and segmentation toolkit,” in 2011 IEEE International Symposium on
Biomedical Imaging: from Nano to Micro, Chicago, Illinois, USA, 2011.'
ista: 'Sommer CM, Straehle C, Köthe U, Hamprecht FA. 2011. Ilastik: Interactive
learning and segmentation toolkit. 2011 IEEE International Symposium on Biomedical
Imaging: from Nano to Micro. ISBI: International Symposium on Biomedical Imaging.'
mla: 'Sommer, Christoph M., et al. “Ilastik: Interactive Learning and Segmentation
Toolkit.” 2011 IEEE International Symposium on Biomedical Imaging: From Nano
to Micro, Institute of Electrical and Electronics Engineers, 2011, doi:10.1109/isbi.2011.5872394.'
short: 'C.M. Sommer, C. Straehle, U. Köthe, F.A. Hamprecht, in:, 2011 IEEE International
Symposium on Biomedical Imaging: From Nano to Micro, Institute of Electrical and
Electronics Engineers, 2011.'
conference:
end_date: 2011-04-02
location: Chicago, Illinois, USA
name: 'ISBI: International Symposium on Biomedical Imaging'
start_date: 2011-03-30
date_created: 2021-08-19T11:49:58Z
date_published: 2011-06-09T00:00:00Z
date_updated: 2023-02-23T14:13:38Z
day: '09'
department:
- _id: Bio
doi: 10.1109/isbi.2011.5872394
extern: '1'
keyword:
- image segmentation
- biomedical imaging
- three dimensional displays
- neurons
- retina
- observers
- image color analysis
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.researchgate.net/publication/224241106_Ilastik_Interactive_learning_and_segmentation_toolkit
month: '06'
oa: 1
oa_version: Preprint
publication: '2011 IEEE International Symposium on Biomedical Imaging: from Nano to
Micro'
publication_identifier:
eissn:
- 1945-8452
isbn:
- 978-1-4244-4127-3
issn:
- 1945-7928
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
status: public
title: 'Ilastik: Interactive learning and segmentation toolkit'
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2011'
...
---
_id: '10908'
abstract:
- lang: eng
text: We present ABC, a software tool for automatically computing symbolic upper
bounds on the number of iterations of nested program loops. The system combines
static analysis of programs with symbolic summation techniques to derive loop
invariant relations between program variables. Iteration bounds are obtained from
the inferred invariants, by replacing variables with bounds on their greatest
values. We have successfully applied ABC to a large number of examples. The derived
symbolic bounds express non-trivial polynomial relations over loop variables.
We also report on results to automatically infer symbolic expressions over harmonic
numbers as upper bounds on loop iteration counts.
acknowledgement: This work was supported in part by the Swiss NSF. The fourth author
is supported by an FWF Hertha Firnberg Research grant (T425-N23).
article_processing_charge: No
author:
- first_name: Régis
full_name: Blanc, Régis
last_name: Blanc
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000-0002-2985-7724
- first_name: Thibaud
full_name: Hottelier, Thibaud
last_name: Hottelier
- first_name: Laura
full_name: Kovács, Laura
last_name: Kovács
citation:
ama: 'Blanc R, Henzinger TA, Hottelier T, Kovács L. ABC: Algebraic Bound Computation
for loops. In: Clarke EM, Voronkov A, eds. Logic for Programming, Artificial
Intelligence, and Reasoning. Vol 6355. LNCS. Berlin, Heidelberg: Springer
Nature; 2010:103-118. doi:10.1007/978-3-642-17511-4_7'
apa: 'Blanc, R., Henzinger, T. A., Hottelier, T., & Kovács, L. (2010). ABC:
Algebraic Bound Computation for loops. In E. M. Clarke & A. Voronkov (Eds.),
Logic for Programming, Artificial Intelligence, and Reasoning (Vol. 6355,
pp. 103–118). Berlin, Heidelberg: Springer Nature. https://doi.org/10.1007/978-3-642-17511-4_7'
chicago: 'Blanc, Régis, Thomas A Henzinger, Thibaud Hottelier, and Laura Kovács.
“ABC: Algebraic Bound Computation for Loops.” In Logic for Programming, Artificial
Intelligence, and Reasoning, edited by Edmund M Clarke and Andrei Voronkov,
6355:103–18. LNCS. Berlin, Heidelberg: Springer Nature, 2010. https://doi.org/10.1007/978-3-642-17511-4_7.'
ieee: 'R. Blanc, T. A. Henzinger, T. Hottelier, and L. Kovács, “ABC: Algebraic Bound
Computation for loops,” in Logic for Programming, Artificial Intelligence,
and Reasoning, Dakar, Senegal, 2010, vol. 6355, pp. 103–118.'
ista: 'Blanc R, Henzinger TA, Hottelier T, Kovács L. 2010. ABC: Algebraic Bound
Computation for loops. Logic for Programming, Artificial Intelligence, and Reasoning.
LPAR: Conference on Logic for Programming, Artificial Intelligence and ReasoningLNCS
vol. 6355, 103–118.'
mla: 'Blanc, Régis, et al. “ABC: Algebraic Bound Computation for Loops.” Logic
for Programming, Artificial Intelligence, and Reasoning, edited by Edmund
M Clarke and Andrei Voronkov, vol. 6355, Springer Nature, 2010, pp. 103–18, doi:10.1007/978-3-642-17511-4_7.'
short: R. Blanc, T.A. Henzinger, T. Hottelier, L. Kovács, in:, E.M. Clarke, A. Voronkov
(Eds.), Logic for Programming, Artificial Intelligence, and Reasoning, Springer
Nature, Berlin, Heidelberg, 2010, pp. 103–118.
conference:
end_date: 2010-05-01
location: Dakar, Senegal
name: 'LPAR: Conference on Logic for Programming, Artificial Intelligence and Reasoning'
start_date: 2010-04-25
date_created: 2022-03-21T08:14:35Z
date_published: 2010-05-01T00:00:00Z
date_updated: 2022-06-13T07:44:21Z
day: '01'
department:
- _id: ToHe
doi: 10.1007/978-3-642-17511-4_7
editor:
- first_name: Edmund M
full_name: Clarke, Edmund M
last_name: Clarke
- first_name: Andrei
full_name: Voronkov, Andrei
last_name: Voronkov
intvolume: ' 6355'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://infoscience.epfl.ch/record/186096
month: '05'
oa: 1
oa_version: Submitted Version
page: 103-118
place: Berlin, Heidelberg
publication: Logic for Programming, Artificial Intelligence, and Reasoning
publication_identifier:
eisbn:
- '9783642175114'
eissn:
- 1611-3349
isbn:
- '9783642175107'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
series_title: LNCS
status: public
title: 'ABC: Algebraic Bound Computation for loops'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6355
year: '2010'
...
---
_id: '10909'
abstract:
- lang: eng
text: We address the problem of localizing homology classes, namely, finding the
cycle representing a given class with the most concise geometric measure. We focus
on the volume measure, that is, the 1-norm of a cycle. Two main results are presented.
First, we prove the problem is NP-hard to approximate within any constant factor.
Second, we prove that for homology of dimension two or higher, the problem is
NP-hard to approximate even when the Betti number is O(1). A side effect is the
inapproximability of the problem of computing the nonbounding cycle with the smallest
volume, and computing cycles representing a homology basis with the minimal total
volume. We also discuss other geometric measures (diameter and radius) and show
their disadvantages in homology localization. Our work is restricted to homology
over the ℤ2 field.
acknowledgement: Partially supported by the Austrian Science Fund under grantFSP-S9103-N04
and P20134-N13.
article_processing_charge: No
author:
- first_name: Chao
full_name: Chen, Chao
id: 3E92416E-F248-11E8-B48F-1D18A9856A87
last_name: Chen
- first_name: Daniel
full_name: Freedman, Daniel
last_name: Freedman
citation:
ama: 'Chen C, Freedman D. Hardness results for homology localization. In: Proceedings
of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms. Society for
Industrial and Applied Mathematics; 2010:1594-1604. doi:10.1137/1.9781611973075.129'
apa: 'Chen, C., & Freedman, D. (2010). Hardness results for homology localization.
In Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms
(pp. 1594–1604). Austin, TX, United States: Society for Industrial and Applied
Mathematics. https://doi.org/10.1137/1.9781611973075.129'
chicago: Chen, Chao, and Daniel Freedman. “Hardness Results for Homology Localization.”
In Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms,
1594–1604. Society for Industrial and Applied Mathematics, 2010. https://doi.org/10.1137/1.9781611973075.129.
ieee: C. Chen and D. Freedman, “Hardness results for homology localization,” in
Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms,
Austin, TX, United States, 2010, pp. 1594–1604.
ista: 'Chen C, Freedman D. 2010. Hardness results for homology localization. Proceedings
of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium
on Discrete Algorithms, 1594–1604.'
mla: Chen, Chao, and Daniel Freedman. “Hardness Results for Homology Localization.”
Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms,
Society for Industrial and Applied Mathematics, 2010, pp. 1594–604, doi:10.1137/1.9781611973075.129.
short: C. Chen, D. Freedman, in:, Proceedings of the 2010 Annual ACM-SIAM Symposium
on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2010,
pp. 1594–1604.
conference:
end_date: 2010-01-19
location: Austin, TX, United States
name: 'SODA: Symposium on Discrete Algorithms'
start_date: 2010-01-17
date_created: 2022-03-21T08:24:07Z
date_published: 2010-02-01T00:00:00Z
date_updated: 2023-02-23T11:19:46Z
day: '01'
department:
- _id: HeEd
doi: 10.1137/1.9781611973075.129
language:
- iso: eng
month: '02'
oa_version: None
page: 1594-1604
publication: Proceedings of the 2010 Annual ACM-SIAM Symposium on Discrete Algorithms
publication_identifier:
eisbn:
- '9781611973075'
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
related_material:
record:
- id: '3267'
relation: later_version
status: public
scopus_import: '1'
status: public
title: Hardness results for homology localization
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2010'
...