---
_id: '5387'
abstract:
- lang: eng
text: We consider Markov Decision Processes (MDPs) with mean-payoff parity and energy
parity objectives. In system design, the parity objective is used to encode ω-regular
specifications, and the mean-payoff and energy objectives can be used to model
quantitative resource constraints. The energy condition re- quires that the resource
level never drops below 0, and the mean-payoff condi- tion requires that the limit-average
value of the resource consumption is within a threshold. While these two (energy
and mean-payoff) classical conditions are equivalent for two-player games, we
show that they differ for MDPs. We show that the problem of deciding whether a
state is almost-sure winning (i.e., winning with probability 1) in energy parity
MDPs is in NP ∩ coNP, while for mean- payoff parity MDPs, the problem is solvable
in polynomial time, improving a recent PSPACE bound.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Laurent
full_name: Doyen, Laurent
last_name: Doyen
citation:
ama: Chatterjee K, Doyen L. Energy and Mean-Payoff Parity Markov Decision Processes.
IST Austria; 2011. doi:10.15479/AT:IST-2011-0001
apa: Chatterjee, K., & Doyen, L. (2011). Energy and mean-payoff parity Markov
decision processes. IST Austria. https://doi.org/10.15479/AT:IST-2011-0001
chicago: Chatterjee, Krishnendu, and Laurent Doyen. Energy and Mean-Payoff Parity
Markov Decision Processes. IST Austria, 2011. https://doi.org/10.15479/AT:IST-2011-0001.
ieee: K. Chatterjee and L. Doyen, Energy and mean-payoff parity Markov decision
processes. IST Austria, 2011.
ista: Chatterjee K, Doyen L. 2011. Energy and mean-payoff parity Markov decision
processes, IST Austria, 20p.
mla: Chatterjee, Krishnendu, and Laurent Doyen. Energy and Mean-Payoff Parity
Markov Decision Processes. IST Austria, 2011, doi:10.15479/AT:IST-2011-0001.
short: K. Chatterjee, L. Doyen, Energy and Mean-Payoff Parity Markov Decision Processes,
IST Austria, 2011.
date_created: 2018-12-12T11:39:02Z
date_published: 2011-02-16T00:00:00Z
date_updated: 2023-02-23T11:23:11Z
day: '16'
ddc:
- '000'
- '005'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2011-0001
file:
- access_level: open_access
checksum: 824d6c70e6d3feb3e836b009e0b3cf73
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:52:57Z
date_updated: 2020-07-14T12:46:41Z
file_id: '5458'
file_name: IST-2011-0001_IST-2011-0001.pdf
file_size: 329976
relation: main_file
file_date_updated: 2020-07-14T12:46:41Z
has_accepted_license: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: '20'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '23'
related_material:
record:
- id: '3345'
relation: later_version
status: public
status: public
title: Energy and mean-payoff parity Markov decision processes
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '6496'
abstract:
- lang: eng
text: We report the switching behavior of the full bacterial flagellum system that
includes the filament and the motor in wild-type Escherichia coli cells. In sorting
the motor behavior by the clockwise bias, we find that the distributions of the
clockwise (CW) and counterclockwise (CCW) intervals are either exponential or
nonexponential with long tails. At low bias, CW intervals are exponentially distributed
and CCW intervals exhibit long tails. At intermediate CW bias (0.5) both CW and
CCW intervals are mainly exponentially distributed. A simple model suggests that
these two distinct switching behaviors are governed by the presence of signaling
noise within the chemotaxis network. Low noise yields exponentially distributed
intervals, whereas large noise yields nonexponential behavior with long tails.
These drastically different motor statistics may play a role in optimizing bacterial
behavior for a wide range of environmental conditions.
article_processing_charge: No
author:
- first_name: Heungwon
full_name: Park, Heungwon
last_name: Park
- first_name: Panos
full_name: Oikonomou, Panos
last_name: Oikonomou
- first_name: Calin C
full_name: Guet, Calin C
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
- first_name: Philippe
full_name: Cluzel, Philippe
last_name: Cluzel
citation:
ama: Park H, Oikonomou P, Guet CC, Cluzel P. Noise underlies switching behavior
of the bacterial flagellum. Biophysical Journal. 2011;101(10):2336-2340.
doi:10.1016/j.bpj.2011.09.040
apa: Park, H., Oikonomou, P., Guet, C. C., & Cluzel, P. (2011). Noise underlies
switching behavior of the bacterial flagellum. Biophysical Journal. Elsevier.
https://doi.org/10.1016/j.bpj.2011.09.040
chicago: Park, Heungwon, Panos Oikonomou, Calin C Guet, and Philippe Cluzel. “Noise
Underlies Switching Behavior of the Bacterial Flagellum.” Biophysical Journal.
Elsevier, 2011. https://doi.org/10.1016/j.bpj.2011.09.040.
ieee: H. Park, P. Oikonomou, C. C. Guet, and P. Cluzel, “Noise underlies switching
behavior of the bacterial flagellum,” Biophysical Journal, vol. 101, no.
10. Elsevier, pp. 2336–2340, 2011.
ista: Park H, Oikonomou P, Guet CC, Cluzel P. 2011. Noise underlies switching behavior
of the bacterial flagellum. Biophysical Journal. 101(10), 2336–2340.
mla: Park, Heungwon, et al. “Noise Underlies Switching Behavior of the Bacterial
Flagellum.” Biophysical Journal, vol. 101, no. 10, Elsevier, 2011, pp.
2336–40, doi:10.1016/j.bpj.2011.09.040.
short: H. Park, P. Oikonomou, C.C. Guet, P. Cluzel, Biophysical Journal 101 (2011)
2336–2340.
date_created: 2019-05-28T11:54:29Z
date_published: 2011-11-16T00:00:00Z
date_updated: 2021-04-16T11:54:49Z
day: '16'
department:
- _id: CaGu
doi: 10.1016/j.bpj.2011.09.040
external_id:
pmid:
- '22098731'
intvolume: ' 101'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218319/
month: '11'
oa: 1
oa_version: Published Version
page: 2336-2340
pmid: 1
publication: Biophysical Journal
publication_identifier:
issn:
- 0006-3495
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Noise underlies switching behavior of the bacterial flagellum
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 101
year: '2011'
...
---
_id: '9483'
abstract:
- lang: eng
text: Imprinted genes are expressed primarily or exclusively from either the maternal
or paternal allele, a phenomenon that occurs in flowering plants and mammals.
Flowering plant imprinted gene expression has been described primarily in endosperm,
a terminal nutritive tissue consumed by the embryo during seed development or
after germination. Imprinted expression in Arabidopsis thaliana endosperm is orchestrated
by differences in cytosine DNA methylation between the paternal and maternal genomes
as well as by Polycomb group proteins. Currently, only 11 imprinted A. thaliana
genes are known. Here, we use extensive sequencing of cDNA libraries to identify
9 paternally expressed and 34 maternally expressed imprinted genes in A. thaliana
endosperm that are regulated by the DNA-demethylating glycosylase DEMETER, the
DNA methyltransferase MET1, and/or the core Polycomb group protein FIE. These
genes encode transcription factors, proteins involved in hormone signaling, components
of the ubiquitin protein degradation pathway, regulators of histone and DNA methylation,
and small RNA pathway proteins. We also identify maternally expressed genes that
may be regulated by unknown mechanisms or deposited from maternal tissues. We
did not detect any imprinted genes in the embryo. Our results show that imprinted
gene expression is an extensive mechanistically complex phenomenon that likely
affects multiple aspects of seed development.
article_processing_charge: No
article_type: original
author:
- first_name: Tzung-Fu
full_name: Hsieh, Tzung-Fu
last_name: Hsieh
- first_name: Juhyun
full_name: Shin, Juhyun
last_name: Shin
- first_name: Rie
full_name: Uzawa, Rie
last_name: Uzawa
- first_name: Pedro
full_name: Silva, Pedro
last_name: Silva
- first_name: Stephanie
full_name: Cohen, Stephanie
last_name: Cohen
- first_name: Matthew J.
full_name: Bauer, Matthew J.
last_name: Bauer
- first_name: Meryl
full_name: Hashimoto, Meryl
last_name: Hashimoto
- first_name: Ryan C.
full_name: Kirkbride, Ryan C.
last_name: Kirkbride
- first_name: John J.
full_name: Harada, John J.
last_name: Harada
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
- first_name: Robert L.
full_name: Fischer, Robert L.
last_name: Fischer
citation:
ama: Hsieh T-F, Shin J, Uzawa R, et al. Regulation of imprinted gene expression
in Arabidopsis endosperm. Proceedings of the National Academy of Sciences.
2011;108(5):1755-1762. doi:10.1073/pnas.1019273108
apa: Hsieh, T.-F., Shin, J., Uzawa, R., Silva, P., Cohen, S., Bauer, M. J., … Fischer,
R. L. (2011). Regulation of imprinted gene expression in Arabidopsis endosperm.
Proceedings of the National Academy of Sciences. National Academy of Sciences.
https://doi.org/10.1073/pnas.1019273108
chicago: Hsieh, Tzung-Fu, Juhyun Shin, Rie Uzawa, Pedro Silva, Stephanie Cohen,
Matthew J. Bauer, Meryl Hashimoto, et al. “Regulation of Imprinted Gene Expression
in Arabidopsis Endosperm.” Proceedings of the National Academy of Sciences.
National Academy of Sciences, 2011. https://doi.org/10.1073/pnas.1019273108.
ieee: T.-F. Hsieh et al., “Regulation of imprinted gene expression in Arabidopsis
endosperm,” Proceedings of the National Academy of Sciences, vol. 108,
no. 5. National Academy of Sciences, pp. 1755–1762, 2011.
ista: Hsieh T-F, Shin J, Uzawa R, Silva P, Cohen S, Bauer MJ, Hashimoto M, Kirkbride
RC, Harada JJ, Zilberman D, Fischer RL. 2011. Regulation of imprinted gene expression
in Arabidopsis endosperm. Proceedings of the National Academy of Sciences. 108(5),
1755–1762.
mla: Hsieh, Tzung-Fu, et al. “Regulation of Imprinted Gene Expression in Arabidopsis
Endosperm.” Proceedings of the National Academy of Sciences, vol. 108,
no. 5, National Academy of Sciences, 2011, pp. 1755–62, doi:10.1073/pnas.1019273108.
short: T.-F. Hsieh, J. Shin, R. Uzawa, P. Silva, S. Cohen, M.J. Bauer, M. Hashimoto,
R.C. Kirkbride, J.J. Harada, D. Zilberman, R.L. Fischer, Proceedings of the National
Academy of Sciences 108 (2011) 1755–1762.
date_created: 2021-06-07T07:40:38Z
date_published: 2011-02-01T00:00:00Z
date_updated: 2021-12-14T08:33:49Z
day: '01'
department:
- _id: DaZi
doi: 10.1073/pnas.1019273108
extern: '1'
external_id:
pmid:
- '21257907'
intvolume: ' 108'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1073/pnas.1019273108
month: '02'
oa: 1
oa_version: Published Version
page: 1755-1762
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
eissn:
- 1091-6490
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Regulation of imprinted gene expression in Arabidopsis endosperm
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 108
year: '2011'
...
---
_id: '9522'
abstract:
- lang: eng
text: Little is known about chromatin remodeling events immediately after fertilization.
A recent report by Autran et al. (2011) in Cell now shows that chromatin regulatory
pathways that silence transposable elements are responsible for global delayed
activation of gene expression in the early Arabidopsis embryo.
article_processing_charge: No
author:
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
citation:
ama: Zilberman D. Balancing Parental Contributions in Plant Embryonic Gene Activation.
Vol 20. Elsevier; 2011:735-736. doi:10.1016/j.devcel.2011.05.018
apa: Zilberman, D. (2011). Balancing parental contributions in plant embryonic
gene activation. Developmental Cell (Vol. 20, pp. 735–736). Elsevier.
https://doi.org/10.1016/j.devcel.2011.05.018
chicago: Zilberman, Daniel. Balancing Parental Contributions in Plant Embryonic
Gene Activation. Developmental Cell. Vol. 20. Elsevier, 2011. https://doi.org/10.1016/j.devcel.2011.05.018.
ieee: D. Zilberman, Balancing parental contributions in plant embryonic gene
activation, vol. 20, no. 6. Elsevier, 2011, pp. 735–736.
ista: Zilberman D. 2011. Balancing parental contributions in plant embryonic gene
activation, Elsevier,p.
mla: Zilberman, Daniel. “Balancing Parental Contributions in Plant Embryonic Gene
Activation.” Developmental Cell, vol. 20, no. 6, Elsevier, 2011, pp. 735–36,
doi:10.1016/j.devcel.2011.05.018.
short: D. Zilberman, Balancing Parental Contributions in Plant Embryonic Gene Activation,
Elsevier, 2011.
date_created: 2021-06-08T06:23:39Z
date_published: 2011-06-14T00:00:00Z
date_updated: 2021-12-14T08:34:37Z
day: '14'
department:
- _id: DaZi
doi: 10.1016/j.devcel.2011.05.018
extern: '1'
external_id:
pmid:
- '21664571'
intvolume: ' 20'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.devcel.2011.05.018
month: '06'
oa: 1
oa_version: Published Version
page: 735-736
pmid: 1
publication: Developmental Cell
publication_identifier:
eissn:
- 1878-1551
issn:
- 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Balancing parental contributions in plant embryonic gene activation
type: other_academic_publication
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 20
year: '2011'
...
---
_id: '9648'
abstract:
- lang: eng
text: In this paper, we establish a correspondence between the incremental algorithm
for computing AT-models [8,9] and the one for computing persistent homology [6,14,15].
We also present a decremental algorithm for computing AT-models that allows to
extend the persistence computation to a wider setting. Finally, we show how to
combine incremental and decremental techniques for persistent homology computation.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Rocio
full_name: Gonzalez-Diaz, Rocio
last_name: Gonzalez-Diaz
- first_name: Adrian
full_name: Ion, Adrian
id: 29F89302-F248-11E8-B48F-1D18A9856A87
last_name: Ion
- first_name: Maria Jose
full_name: Jimenez, Maria Jose
last_name: Jimenez
- first_name: Regina
full_name: Poyatos, Regina
last_name: Poyatos
citation:
ama: 'Gonzalez-Diaz R, Ion A, Jimenez MJ, Poyatos R. Incremental-decremental algorithm
for computing AT-models and persistent homology. In: Computer Analysis of Images
and Patterns. Vol 6854. Springer Nature; 2011:286-293. doi:10.1007/978-3-642-23672-3_35'
apa: 'Gonzalez-Diaz, R., Ion, A., Jimenez, M. J., & Poyatos, R. (2011). Incremental-decremental
algorithm for computing AT-models and persistent homology. In Computer Analysis
of Images and Patterns (Vol. 6854, pp. 286–293). Seville, Spain: Springer
Nature. https://doi.org/10.1007/978-3-642-23672-3_35'
chicago: Gonzalez-Diaz, Rocio, Adrian Ion, Maria Jose Jimenez, and Regina Poyatos.
“Incremental-Decremental Algorithm for Computing AT-Models and Persistent Homology.”
In Computer Analysis of Images and Patterns, 6854:286–93. Springer Nature,
2011. https://doi.org/10.1007/978-3-642-23672-3_35.
ieee: R. Gonzalez-Diaz, A. Ion, M. J. Jimenez, and R. Poyatos, “Incremental-decremental
algorithm for computing AT-models and persistent homology,” in Computer Analysis
of Images and Patterns, Seville, Spain, 2011, vol. 6854, pp. 286–293.
ista: 'Gonzalez-Diaz R, Ion A, Jimenez MJ, Poyatos R. 2011. Incremental-decremental
algorithm for computing AT-models and persistent homology. Computer Analysis of
Images and Patterns. CAIP: International Conference on Computer Analysis of Images
and Patterns, LNCS, vol. 6854, 286–293.'
mla: Gonzalez-Diaz, Rocio, et al. “Incremental-Decremental Algorithm for Computing
AT-Models and Persistent Homology.” Computer Analysis of Images and Patterns,
vol. 6854, Springer Nature, 2011, pp. 286–93, doi:10.1007/978-3-642-23672-3_35.
short: R. Gonzalez-Diaz, A. Ion, M.J. Jimenez, R. Poyatos, in:, Computer Analysis
of Images and Patterns, Springer Nature, 2011, pp. 286–293.
conference:
end_date: 2011-08-31
location: Seville, Spain
name: 'CAIP: International Conference on Computer Analysis of Images and Patterns'
start_date: 2011-08-29
date_created: 2021-07-11T22:01:19Z
date_published: 2011-08-01T00:00:00Z
date_updated: 2021-08-12T13:53:17Z
day: '01'
department:
- _id: HeEd
doi: 10.1007/978-3-642-23672-3_35
intvolume: ' 6854'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://hdl.handle.net/11441/30766
month: '08'
oa: 1
oa_version: Published Version
page: 286-293
publication: Computer Analysis of Images and Patterns
publication_identifier:
eissn:
- '16113349'
isbn:
- '9783642236716'
issn:
- '03029743'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Incremental-decremental algorithm for computing AT-models and persistent homology
type: conference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
volume: 6854
year: '2011'
...
---
_id: '9762'
abstract:
- lang: eng
text: Defining population structure and genetic diversity levels is of the utmost
importance for developing efficient conservation strategies. Overfishing has caused
mean annual catches of the European spiny lobster (Palinurus elephas) to decrease
alarmingly along its distribution area. In this context, there is a need for comprehensive
studies to evaluate the genetic health of the exploited populations. The present
work is based on a set of 10 nuclear markers amplified in 331 individuals from
10 different localities covering most of P. elephas distribution area. Samples
from Atlantic and Mediterranean basins showed small but significant differences,
indicating that P. elephas populations do not behave as a single panmictic unit
but form two partially-overlapping groups. Despite intense overfishing, our dataset
did not recover a recent bottleneck signal, and showed a large and stable historical
effective size instead. This result could be accounted for by specific life history
traits (reproduction and longevity) and the limitations of molecular markers in
covering very recent timescales for non temporal samples. Our study emphasizes
the necessity of integrating information on effective population sizes and life
history parameters when evaluating population connectivity levels from genetic
data.
article_processing_charge: No
author:
- first_name: Ferran
full_name: Palero, Ferran
id: 3F0E2A22-F248-11E8-B48F-1D18A9856A87
last_name: Palero
orcid: 0000-0002-0343-8329
- first_name: Pere
full_name: Abello, Pere
last_name: Abello
- first_name: Enrique
full_name: Macpherson, Enrique
last_name: Macpherson
- first_name: Mark
full_name: Beaumont, Mark
last_name: Beaumont
- first_name: Marta
full_name: Pascual, Marta
last_name: Pascual
citation:
ama: 'Palero F, Abello P, Macpherson E, Beaumont M, Pascual M. Data from: Effect
of oceanographic barriers and overfishing on the population genetic structure
of the European spiny lobster (Palinurus elephas). 2011. doi:10.5061/dryad.299h8'
apa: 'Palero, F., Abello, P., Macpherson, E., Beaumont, M., & Pascual, M. (2011).
Data from: Effect of oceanographic barriers and overfishing on the population
genetic structure of the European spiny lobster (Palinurus elephas). IST Austria.
https://doi.org/10.5061/dryad.299h8'
chicago: 'Palero, Ferran, Pere Abello, Enrique Macpherson, Mark Beaumont, and Marta
Pascual. “Data from: Effect of Oceanographic Barriers and Overfishing on the Population
Genetic Structure of the European Spiny Lobster (Palinurus Elephas).” IST Austria,
2011. https://doi.org/10.5061/dryad.299h8.'
ieee: 'F. Palero, P. Abello, E. Macpherson, M. Beaumont, and M. Pascual, “Data from:
Effect of oceanographic barriers and overfishing on the population genetic structure
of the European spiny lobster (Palinurus elephas).” IST Austria, 2011.'
ista: 'Palero F, Abello P, Macpherson E, Beaumont M, Pascual M. 2011. Data from:
Effect of oceanographic barriers and overfishing on the population genetic structure
of the European spiny lobster (Palinurus elephas), IST Austria, 10.5061/dryad.299h8.'
mla: 'Palero, Ferran, et al. Data from: Effect of Oceanographic Barriers and
Overfishing on the Population Genetic Structure of the European Spiny Lobster
(Palinurus Elephas). IST Austria, 2011, doi:10.5061/dryad.299h8.'
short: F. Palero, P. Abello, E. Macpherson, M. Beaumont, M. Pascual, (2011).
date_created: 2021-08-02T07:11:19Z
date_published: 2011-05-12T00:00:00Z
date_updated: 2023-02-23T11:25:25Z
day: '12'
department:
- _id: NiBa
doi: 10.5061/dryad.299h8
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.299h8
month: '05'
oa: 1
oa_version: Published Version
publisher: IST Austria
related_material:
record:
- id: '3395'
relation: used_in_publication
status: public
status: public
title: 'Data from: Effect of oceanographic barriers and overfishing on the population
genetic structure of the European spiny lobster (Palinurus elephas)'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2011'
...
---
_id: '9943'
abstract:
- lang: eng
text: Segmentation is the process of partitioning digital images into meaningful
regions. The analysis of biological high content images often requires segmentation
as a first step. We propose ilastik as an easy-to-use tool which allows the user
without expertise in image processing to perform segmentation and classification
in a unified way. ilastik learns from labels provided by the user through a convenient
mouse interface. Based on these labels, ilastik infers a problem specific segmentation.
A random forest classifier is used in the learning step, in which each pixel's
neighborhood is characterized by a set of generic (nonlinear) features. ilastik
supports up to three spatial plus one spectral dimension and makes use of all
dimensions in the feature calculation. ilastik provides realtime feedback that
enables the user to interactively refine the segmentation result and hence further
fine-tune the classifier. An uncertainty measure guides the user to ambiguous
regions in the images. Real time performance is achieved by multi-threading which
fully exploits the capabilities of modern multi-core machines. Once a classifier
has been trained on a set of representative images, it can be exported and used
to automatically process a very large number of images (e.g. using the CellProfiler
pipeline). ilastik is an open source project and released under the BSD license
at www.ilastik.org.
article_processing_charge: No
author:
- first_name: Christoph M
full_name: Sommer, Christoph M
id: 4DF26D8C-F248-11E8-B48F-1D18A9856A87
last_name: Sommer
orcid: 0000-0003-1216-9105
- first_name: Christoph
full_name: Straehle, Christoph
last_name: Straehle
- first_name: Ullrich
full_name: Köthe, Ullrich
last_name: Köthe
- first_name: Fred A.
full_name: Hamprecht, Fred A.
last_name: Hamprecht
citation:
ama: 'Sommer CM, Straehle C, Köthe U, Hamprecht FA. Ilastik: Interactive learning
and segmentation toolkit. In: 2011 IEEE International Symposium on Biomedical
Imaging: From Nano to Micro. Institute of Electrical and Electronics Engineers;
2011. doi:10.1109/isbi.2011.5872394'
apa: 'Sommer, C. M., Straehle, C., Köthe, U., & Hamprecht, F. A. (2011). Ilastik:
Interactive learning and segmentation toolkit. In 2011 IEEE International Symposium
on Biomedical Imaging: from Nano to Micro. Chicago, Illinois, USA: Institute
of Electrical and Electronics Engineers. https://doi.org/10.1109/isbi.2011.5872394'
chicago: 'Sommer, Christoph M, Christoph Straehle, Ullrich Köthe, and Fred A. Hamprecht.
“Ilastik: Interactive Learning and Segmentation Toolkit.” In 2011 IEEE International
Symposium on Biomedical Imaging: From Nano to Micro. Institute of Electrical
and Electronics Engineers, 2011. https://doi.org/10.1109/isbi.2011.5872394.'
ieee: 'C. M. Sommer, C. Straehle, U. Köthe, and F. A. Hamprecht, “Ilastik: Interactive
learning and segmentation toolkit,” in 2011 IEEE International Symposium on
Biomedical Imaging: from Nano to Micro, Chicago, Illinois, USA, 2011.'
ista: 'Sommer CM, Straehle C, Köthe U, Hamprecht FA. 2011. Ilastik: Interactive
learning and segmentation toolkit. 2011 IEEE International Symposium on Biomedical
Imaging: from Nano to Micro. ISBI: International Symposium on Biomedical Imaging.'
mla: 'Sommer, Christoph M., et al. “Ilastik: Interactive Learning and Segmentation
Toolkit.” 2011 IEEE International Symposium on Biomedical Imaging: From Nano
to Micro, Institute of Electrical and Electronics Engineers, 2011, doi:10.1109/isbi.2011.5872394.'
short: 'C.M. Sommer, C. Straehle, U. Köthe, F.A. Hamprecht, in:, 2011 IEEE International
Symposium on Biomedical Imaging: From Nano to Micro, Institute of Electrical and
Electronics Engineers, 2011.'
conference:
end_date: 2011-04-02
location: Chicago, Illinois, USA
name: 'ISBI: International Symposium on Biomedical Imaging'
start_date: 2011-03-30
date_created: 2021-08-19T11:49:58Z
date_published: 2011-06-09T00:00:00Z
date_updated: 2023-02-23T14:13:38Z
day: '09'
department:
- _id: Bio
doi: 10.1109/isbi.2011.5872394
extern: '1'
keyword:
- image segmentation
- biomedical imaging
- three dimensional displays
- neurons
- retina
- observers
- image color analysis
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.researchgate.net/publication/224241106_Ilastik_Interactive_learning_and_segmentation_toolkit
month: '06'
oa: 1
oa_version: Preprint
publication: '2011 IEEE International Symposium on Biomedical Imaging: from Nano to
Micro'
publication_identifier:
eissn:
- 1945-8452
isbn:
- 978-1-4244-4127-3
issn:
- 1945-7928
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
status: public
title: 'Ilastik: Interactive learning and segmentation toolkit'
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2011'
...
---
_id: '10907'
abstract:
- lang: eng
text: This paper presents a method to create a model of an articulated object using
the planar motion in an initialization video. The model consists of rigid parts
connected by points of articulation. The rigid parts are described by the positions
of salient feature-points tracked throughout the video. Following a filtering
step that identifies points that belong to different objects, rigid parts are
found by a grouping process in a graph pyramid. Valid articulation points are
selected by verifying multiple hypotheses for each pair of parts.
acknowledgement: This work has been partially supported by the Austrian Science Fund
under grants S9103-N13 and P18716-N13.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Nicole M.
full_name: Artner, Nicole M.
last_name: Artner
- first_name: Adrian
full_name: Ion, Adrian
id: 29F89302-F248-11E8-B48F-1D18A9856A87
last_name: Ion
- first_name: Walter G.
full_name: Kropatsch, Walter G.
last_name: Kropatsch
citation:
ama: 'Artner NM, Ion A, Kropatsch WG. Spatio-temporal extraction of articulated
models in a graph pyramid. In: Jiang X, Ferrer M, Torsello A, eds. Graph-Based
Representations in Pattern Recognition. Vol 6658. LNIP. Berlin, Heidelberg:
Springer; 2011:215-224. doi:10.1007/978-3-642-20844-7_22'
apa: 'Artner, N. M., Ion, A., & Kropatsch, W. G. (2011). Spatio-temporal extraction
of articulated models in a graph pyramid. In X. Jiang, M. Ferrer, & A. Torsello
(Eds.), Graph-Based Representations in Pattern Recognition (Vol. 6658,
pp. 215–224). Berlin, Heidelberg: Springer. https://doi.org/10.1007/978-3-642-20844-7_22'
chicago: 'Artner, Nicole M., Adrian Ion, and Walter G. Kropatsch. “Spatio-Temporal
Extraction of Articulated Models in a Graph Pyramid.” In Graph-Based Representations
in Pattern Recognition, edited by Xiaoyi Jiang, Miquel Ferrer, and Andrea
Torsello, 6658:215–24. LNIP. Berlin, Heidelberg: Springer, 2011. https://doi.org/10.1007/978-3-642-20844-7_22.'
ieee: N. M. Artner, A. Ion, and W. G. Kropatsch, “Spatio-temporal extraction of
articulated models in a graph pyramid,” in Graph-Based Representations in Pattern
Recognition, Münster, Germany, 2011, vol. 6658, pp. 215–224.
ista: 'Artner NM, Ion A, Kropatsch WG. 2011. Spatio-temporal extraction of articulated
models in a graph pyramid. Graph-Based Representations in Pattern Recognition.
GbRPR: Graph-based Representations in Pattern RecognitionLNIP, LNCS, vol. 6658,
215–224.'
mla: Artner, Nicole M., et al. “Spatio-Temporal Extraction of Articulated Models
in a Graph Pyramid.” Graph-Based Representations in Pattern Recognition,
edited by Xiaoyi Jiang et al., vol. 6658, Springer, 2011, pp. 215–24, doi:10.1007/978-3-642-20844-7_22.
short: N.M. Artner, A. Ion, W.G. Kropatsch, in:, X. Jiang, M. Ferrer, A. Torsello
(Eds.), Graph-Based Representations in Pattern Recognition, Springer, Berlin,
Heidelberg, 2011, pp. 215–224.
conference:
end_date: 2011-05-20
location: Münster, Germany
name: 'GbRPR: Graph-based Representations in Pattern Recognition'
start_date: 2011-05-18
date_created: 2022-03-21T08:08:35Z
date_published: 2011-06-01T00:00:00Z
date_updated: 2023-09-05T14:10:15Z
day: '01'
department:
- _id: HeEd
doi: 10.1007/978-3-642-20844-7_22
editor:
- first_name: Xiaoyi
full_name: Jiang, Xiaoyi
last_name: Jiang
- first_name: Miquel
full_name: Ferrer, Miquel
last_name: Ferrer
- first_name: Andrea
full_name: Torsello, Andrea
last_name: Torsello
intvolume: ' 6658'
language:
- iso: eng
month: '06'
oa_version: None
page: 215-224
place: Berlin, Heidelberg
publication: Graph-Based Representations in Pattern Recognition
publication_identifier:
eisbn:
- '9783642208447'
eissn:
- 1611-3349
isbn:
- '9783642208430'
issn:
- 0302-9743
publication_status: published
publisher: Springer
quality_controlled: '1'
scopus_import: '1'
series_title: LNIP
status: public
title: Spatio-temporal extraction of articulated models in a graph pyramid
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 6658
year: '2011'
...
---
_id: '3163'
abstract:
- lang: eng
text: We study multi-label prediction for structured output sets, a problem that
occurs, for example, in object detection in images, secondary structure prediction
in computational biology, and graph matching with symmetries. Conventional multilabel
classification techniques are typically not applicable in this situation, because
they require explicit enumeration of the label set, which is infeasible in case
of structured outputs. Relying on techniques originally designed for single-label
structured prediction, in particular structured support vector machines, results
in reduced prediction accuracy, or leads to infeasible optimization problems.
In this work we derive a maximum-margin training formulation for multi-label structured
prediction that remains computationally tractable while achieving high prediction
accuracy. It also shares most beneficial properties with single-label maximum-margin
approaches, in particular formulation as a convex optimization problem, efficient
working set training, and PAC-Bayesian generalization bounds.
author:
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Lampert C. Maximum margin multi-label structured prediction. In: Neural Information
Processing Systems; 2011.'
apa: 'Lampert, C. (2011). Maximum margin multi-label structured prediction. Presented
at the NIPS: Neural Information Processing Systems, Granada, Spain: Neural Information
Processing Systems.'
chicago: Lampert, Christoph. “Maximum Margin Multi-Label Structured Prediction.”
Neural Information Processing Systems, 2011.
ieee: 'C. Lampert, “Maximum margin multi-label structured prediction,” presented
at the NIPS: Neural Information Processing Systems, Granada, Spain, 2011.'
ista: 'Lampert C. 2011. Maximum margin multi-label structured prediction. NIPS:
Neural Information Processing Systems.'
mla: Lampert, Christoph. Maximum Margin Multi-Label Structured Prediction.
Neural Information Processing Systems, 2011.
short: C. Lampert, in:, Neural Information Processing Systems, 2011.
conference:
end_date: 2011-12-14
location: Granada, Spain
name: 'NIPS: Neural Information Processing Systems'
start_date: 2011-12-12
date_created: 2018-12-11T12:01:45Z
date_published: 2011-12-01T00:00:00Z
date_updated: 2023-10-17T11:47:35Z
day: '01'
department:
- _id: ChLa
language:
- iso: eng
month: '12'
oa_version: None
publication_status: published
publisher: Neural Information Processing Systems
publist_id: '3522'
quality_controlled: '1'
related_material:
record:
- id: '3322'
relation: later_version
status: public
scopus_import: 1
status: public
title: Maximum margin multi-label structured prediction
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3264'
abstract:
- lang: eng
text: Verification of programs with procedures, multi-threaded programs, and higher-order
functional programs can be effectively au- tomated using abstraction and refinement
schemes that rely on spurious counterexamples for abstraction discovery. The analysis
of counterexam- ples can be automated by a series of interpolation queries, or,
alterna- tively, as a constraint solving query expressed by a set of recursion
free Horn clauses. (A set of interpolation queries can be formulated as a single
constraint over Horn clauses with linear dependency structure between the unknown
relations.) In this paper we present an algorithm for solving recursion free Horn
clauses over a combined theory of linear real/rational arithmetic and uninterpreted
functions. Our algorithm performs resolu- tion to deal with the clausal structure
and relies on partial solutions to deal with (non-local) instances of functionality
axioms.
alternative_title:
- LNCS
author:
- first_name: Ashutosh
full_name: Gupta, Ashutosh
id: 335E5684-F248-11E8-B48F-1D18A9856A87
last_name: Gupta
- first_name: Corneliu
full_name: Popeea, Corneliu
last_name: Popeea
- first_name: Andrey
full_name: Rybalchenko, Andrey
last_name: Rybalchenko
citation:
ama: 'Gupta A, Popeea C, Rybalchenko A. Solving recursion-free Horn clauses over
LI+UIF. In: Yang H, ed. Vol 7078. Springer; 2011:188-203. doi:10.1007/978-3-642-25318-8_16'
apa: 'Gupta, A., Popeea, C., & Rybalchenko, A. (2011). Solving recursion-free
Horn clauses over LI+UIF. In H. Yang (Ed.) (Vol. 7078, pp. 188–203). Presented
at the APLAS: Asian Symposium on Programming Languages and Systems, Kenting, Taiwan:
Springer. https://doi.org/10.1007/978-3-642-25318-8_16'
chicago: Gupta, Ashutosh, Corneliu Popeea, and Andrey Rybalchenko. “Solving Recursion-Free
Horn Clauses over LI+UIF.” edited by Hongseok Yang, 7078:188–203. Springer, 2011.
https://doi.org/10.1007/978-3-642-25318-8_16.
ieee: 'A. Gupta, C. Popeea, and A. Rybalchenko, “Solving recursion-free Horn clauses
over LI+UIF,” presented at the APLAS: Asian Symposium on Programming Languages
and Systems, Kenting, Taiwan, 2011, vol. 7078, pp. 188–203.'
ista: 'Gupta A, Popeea C, Rybalchenko A. 2011. Solving recursion-free Horn clauses
over LI+UIF. APLAS: Asian Symposium on Programming Languages and Systems, LNCS,
vol. 7078, 188–203.'
mla: Gupta, Ashutosh, et al. Solving Recursion-Free Horn Clauses over LI+UIF.
Edited by Hongseok Yang, vol. 7078, Springer, 2011, pp. 188–203, doi:10.1007/978-3-642-25318-8_16.
short: A. Gupta, C. Popeea, A. Rybalchenko, in:, H. Yang (Ed.), Springer, 2011,
pp. 188–203.
conference:
end_date: 2011-12-07
location: Kenting, Taiwan
name: 'APLAS: Asian Symposium on Programming Languages and Systems'
start_date: 2011-12-05
date_created: 2018-12-11T12:02:20Z
date_published: 2011-12-05T00:00:00Z
date_updated: 2021-01-12T07:42:15Z
day: '05'
department:
- _id: ToHe
doi: 10.1007/978-3-642-25318-8_16
ec_funded: 1
editor:
- first_name: Hongseok
full_name: Yang, Hongseok
last_name: Yang
intvolume: ' 7078'
language:
- iso: eng
month: '12'
oa_version: None
page: 188 - 203
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
publication_status: published
publisher: Springer
publist_id: '3383'
quality_controlled: '1'
status: public
title: Solving recursion-free Horn clauses over LI+UIF
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 7078
year: '2011'
...
---
_id: '3266'
abstract:
- lang: eng
text: We present a joint image segmentation and labeling model (JSL) which, given
a bag of figure-ground segment hypotheses extracted at multiple image locations
and scales, constructs a joint probability distribution over both the compatible
image interpretations (tilings or image segmentations) composed from those segments,
and over their labeling into categories. The process of drawing samples from the
joint distribution can be interpreted as first sampling tilings, modeled as maximal
cliques, from a graph connecting spatially non-overlapping segments in the bag
[1], followed by sampling labels for those segments, conditioned on the choice
of a particular tiling. We learn the segmentation and labeling parameters jointly,
based on Maximum Likelihood with a novel Incremental Saddle Point estimation procedure.
The partition function over tilings and labelings is increasingly more accurately
approximated by including incorrect configurations that a not-yet-competent model
rates probable during learning. We show that the proposed methodologymatches the
current state of the art in the Stanford dataset [2], as well as in VOC2010, where
41.7% accuracy on the test set is achieved.
author:
- first_name: Adrian
full_name: Ion, Adrian
id: 29F89302-F248-11E8-B48F-1D18A9856A87
last_name: Ion
- first_name: Joao
full_name: Carreira, Joao
last_name: Carreira
- first_name: Cristian
full_name: Sminchisescu, Cristian
last_name: Sminchisescu
citation:
ama: 'Ion A, Carreira J, Sminchisescu C. Probabilistic joint image segmentation
and labeling. In: NIPS Proceedings. Vol 24. Neural Information Processing
Systems Foundation; 2011:1827-1835.'
apa: 'Ion, A., Carreira, J., & Sminchisescu, C. (2011). Probabilistic joint
image segmentation and labeling. In NIPS Proceedings (Vol. 24, pp. 1827–1835).
Granada, Spain: Neural Information Processing Systems Foundation.'
chicago: Ion, Adrian, Joao Carreira, and Cristian Sminchisescu. “Probabilistic Joint
Image Segmentation and Labeling.” In NIPS Proceedings, 24:1827–35. Neural
Information Processing Systems Foundation, 2011.
ieee: A. Ion, J. Carreira, and C. Sminchisescu, “Probabilistic joint image segmentation
and labeling,” in NIPS Proceedings, Granada, Spain, 2011, vol. 24, pp.
1827–1835.
ista: 'Ion A, Carreira J, Sminchisescu C. 2011. Probabilistic joint image segmentation
and labeling. NIPS Proceedings. NIPS: Neural Information Processing Systems vol.
24, 1827–1835.'
mla: Ion, Adrian, et al. “Probabilistic Joint Image Segmentation and Labeling.”
NIPS Proceedings, vol. 24, Neural Information Processing Systems Foundation,
2011, pp. 1827–35.
short: A. Ion, J. Carreira, C. Sminchisescu, in:, NIPS Proceedings, Neural Information
Processing Systems Foundation, 2011, pp. 1827–1835.
conference:
end_date: 2011-12-14
location: Granada, Spain
name: 'NIPS: Neural Information Processing Systems'
start_date: 2011-12-12
date_created: 2018-12-11T12:02:21Z
date_published: 2011-12-01T00:00:00Z
date_updated: 2021-01-12T07:42:15Z
day: '01'
department:
- _id: HeEd
intvolume: ' 24'
language:
- iso: eng
month: '12'
oa_version: None
page: 1827 - 1835
publication: NIPS Proceedings
publication_status: published
publisher: Neural Information Processing Systems Foundation
publist_id: '3381'
quality_controlled: '1'
scopus_import: 1
status: public
title: Probabilistic joint image segmentation and labeling
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2011'
...
---
_id: '3267'
abstract:
- lang: eng
text: 'We address the problem of localizing homology classes, namely, finding the
cycle representing a given class with the most concise geometric measure. We study
the problem with different measures: volume, diameter and radius. For volume,
that is, the 1-norm of a cycle, two main results are presented. First, we prove
that the problem is NP-hard to approximate within any constant factor. Second,
we prove that for homology of dimension two or higher, the problem is NP-hard
to approximate even when the Betti number is O(1). The latter result leads to
the inapproximability of the problem of computing the nonbounding cycle with the
smallest volume and computing cycles representing a homology basis with the minimal
total volume. As for the other two measures defined by pairwise geodesic distance,
diameter and radius, we show that the localization problem is NP-hard for diameter
but is polynomial for radius. Our work is restricted to homology over the ℤ2 field.'
author:
- first_name: Chao
full_name: Chen, Chao
id: 3E92416E-F248-11E8-B48F-1D18A9856A87
last_name: Chen
- first_name: Daniel
full_name: Freedman, Daniel
last_name: Freedman
citation:
ama: Chen C, Freedman D. Hardness results for homology localization. Discrete
& Computational Geometry. 2011;45(3):425-448. doi:10.1007/s00454-010-9322-8
apa: Chen, C., & Freedman, D. (2011). Hardness results for homology localization.
Discrete & Computational Geometry. Springer. https://doi.org/10.1007/s00454-010-9322-8
chicago: Chen, Chao, and Daniel Freedman. “Hardness Results for Homology Localization.”
Discrete & Computational Geometry. Springer, 2011. https://doi.org/10.1007/s00454-010-9322-8.
ieee: C. Chen and D. Freedman, “Hardness results for homology localization,” Discrete
& Computational Geometry, vol. 45, no. 3. Springer, pp. 425–448, 2011.
ista: Chen C, Freedman D. 2011. Hardness results for homology localization. Discrete
& Computational Geometry. 45(3), 425–448.
mla: Chen, Chao, and Daniel Freedman. “Hardness Results for Homology Localization.”
Discrete & Computational Geometry, vol. 45, no. 3, Springer, 2011,
pp. 425–48, doi:10.1007/s00454-010-9322-8.
short: C. Chen, D. Freedman, Discrete & Computational Geometry 45 (2011) 425–448.
date_created: 2018-12-11T12:02:21Z
date_published: 2011-01-14T00:00:00Z
date_updated: 2023-02-21T16:07:10Z
day: '14'
department:
- _id: HeEd
doi: 10.1007/s00454-010-9322-8
intvolume: ' 45'
issue: '3'
language:
- iso: eng
month: '01'
oa_version: None
page: 425 - 448
publication: Discrete & Computational Geometry
publication_status: published
publisher: Springer
publist_id: '3379'
quality_controlled: '1'
related_material:
record:
- id: '10909'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Hardness results for homology localization
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 45
year: '2011'
...
---
_id: '3269'
abstract:
- lang: eng
text: The unintentional scattering of light between neighboring surfaces in complex
projection environments increases the brightness and decreases the contrast, disrupting
the appearance of the desired imagery. To achieve satisfactory projection results,
the inverse problem of global illumination must be solved to cancel this secondary
scattering. In this paper, we propose a global illumination cancellation method
that minimizes the perceptual difference between the desired imagery and the actual
total illumination in the resulting physical environment. Using Gauss-Newton and
active set methods, we design a fast solver for the bound constrained nonlinear
least squares problem raised by the perceptual error metrics. Our solver is further
accelerated with a CUDA implementation and multi-resolution method to achieve
1–2 fps for problems with approximately 3000 variables. We demonstrate the global
illumination cancellation algorithm with our multi-projector system. Results show
that our method preserves the color fidelity of the desired imagery significantly
better than previous methods.
article_processing_charge: No
article_type: original
author:
- first_name: Yu
full_name: Sheng, Yu
last_name: Sheng
- first_name: Barbara
full_name: Cutler, Barbara
last_name: Cutler
- first_name: Chao
full_name: Chen, Chao
id: 3E92416E-F248-11E8-B48F-1D18A9856A87
last_name: Chen
- first_name: Joshua
full_name: Nasman, Joshua
last_name: Nasman
citation:
ama: Sheng Y, Cutler B, Chen C, Nasman J. Perceptual global illumination cancellation
in complex projection environments. Computer Graphics Forum. 2011;30(4):1261-1268.
doi:10.1111/j.1467-8659.2011.01985.x
apa: Sheng, Y., Cutler, B., Chen, C., & Nasman, J. (2011). Perceptual global
illumination cancellation in complex projection environments. Computer Graphics
Forum. Wiley-Blackwell. https://doi.org/10.1111/j.1467-8659.2011.01985.x
chicago: Sheng, Yu, Barbara Cutler, Chao Chen, and Joshua Nasman. “Perceptual Global
Illumination Cancellation in Complex Projection Environments.” Computer Graphics
Forum. Wiley-Blackwell, 2011. https://doi.org/10.1111/j.1467-8659.2011.01985.x.
ieee: Y. Sheng, B. Cutler, C. Chen, and J. Nasman, “Perceptual global illumination
cancellation in complex projection environments,” Computer Graphics Forum,
vol. 30, no. 4. Wiley-Blackwell, pp. 1261–1268, 2011.
ista: Sheng Y, Cutler B, Chen C, Nasman J. 2011. Perceptual global illumination
cancellation in complex projection environments. Computer Graphics Forum. 30(4),
1261–1268.
mla: Sheng, Yu, et al. “Perceptual Global Illumination Cancellation in Complex Projection
Environments.” Computer Graphics Forum, vol. 30, no. 4, Wiley-Blackwell,
2011, pp. 1261–68, doi:10.1111/j.1467-8659.2011.01985.x.
short: Y. Sheng, B. Cutler, C. Chen, J. Nasman, Computer Graphics Forum 30 (2011)
1261–1268.
date_created: 2018-12-11T12:02:22Z
date_published: 2011-07-19T00:00:00Z
date_updated: 2021-01-12T07:42:16Z
day: '19'
department:
- _id: HeEd
doi: 10.1111/j.1467-8659.2011.01985.x
intvolume: ' 30'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.cs.cmu.edu/%7Eshengyu/download/egsr2011_paper.pdf
month: '07'
oa: 1
oa_version: Published Version
page: 1261 - 1268
publication: Computer Graphics Forum
publication_status: published
publisher: Wiley-Blackwell
publist_id: '3377'
quality_controlled: '1'
scopus_import: 1
status: public
title: Perceptual global illumination cancellation in complex projection environments
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 30
year: '2011'
...
---
_id: '3270'
abstract:
- lang: eng
text: 'The persistence diagram of a filtered simplicial com- plex is usually computed
by reducing the boundary matrix of the complex. We introduce a simple op- timization
technique: by processing the simplices of the complex in decreasing dimension,
we can “kill” columns (i.e., set them to zero) without reducing them. This technique
completely avoids reduction on roughly half of the columns. We demonstrate that
this idea significantly improves the running time of the reduction algorithm in
practice. We also give an output-sensitive complexity analysis for the new al-
gorithm which yields to sub-cubic asymptotic bounds under certain assumptions.'
author:
- first_name: Chao
full_name: Chen, Chao
id: 3E92416E-F248-11E8-B48F-1D18A9856A87
last_name: Chen
- first_name: Michael
full_name: Kerber, Michael
id: 36E4574A-F248-11E8-B48F-1D18A9856A87
last_name: Kerber
orcid: 0000-0002-8030-9299
citation:
ama: 'Chen C, Kerber M. Persistent homology computation with a twist. In: TU Dortmund;
2011:197-200.'
apa: 'Chen, C., & Kerber, M. (2011). Persistent homology computation with a
twist (pp. 197–200). Presented at the EuroCG: European Workshop on Computational
Geometry, Morschach, Switzerland: TU Dortmund.'
chicago: Chen, Chao, and Michael Kerber. “Persistent Homology Computation with a
Twist,” 197–200. TU Dortmund, 2011.
ieee: 'C. Chen and M. Kerber, “Persistent homology computation with a twist,” presented
at the EuroCG: European Workshop on Computational Geometry, Morschach, Switzerland,
2011, pp. 197–200.'
ista: 'Chen C, Kerber M. 2011. Persistent homology computation with a twist. EuroCG:
European Workshop on Computational Geometry, 197–200.'
mla: Chen, Chao, and Michael Kerber. Persistent Homology Computation with a Twist.
TU Dortmund, 2011, pp. 197–200.
short: C. Chen, M. Kerber, in:, TU Dortmund, 2011, pp. 197–200.
conference:
end_date: 2011-03-30
location: Morschach, Switzerland
name: 'EuroCG: European Workshop on Computational Geometry'
start_date: 2011-03-28
date_created: 2018-12-11T12:02:22Z
date_published: 2011-01-01T00:00:00Z
date_updated: 2021-01-12T07:42:17Z
day: '01'
department:
- _id: HeEd
language:
- iso: eng
month: '01'
oa_version: None
page: 197 - 200
publication_status: published
publisher: TU Dortmund
publist_id: '3376'
quality_controlled: '1'
status: public
title: Persistent homology computation with a twist
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3271'
abstract:
- lang: eng
text: In this paper we present an efficient framework for computation of persis-
tent homology of cubical data in arbitrary dimensions. An existing algorithm using
simplicial complexes is adapted to the setting of cubical complexes. The proposed
approach enables efficient application of persistent homology in domains where
the data is naturally given in a cubical form. By avoiding triangulation of the
data, we significantly reduce the size of the complex. We also present a data-structure
de- signed to compactly store and quickly manipulate cubical complexes. By means
of numerical experiments, we show high speed and memory efficiency of our ap-
proach. We compare our framework to other available implementations, showing its
superiority. Finally, we report performance on selected 3D and 4D data-sets.
alternative_title:
- Theory, Algorithms, and Applications
author:
- first_name: Hubert
full_name: Wagner, Hubert
last_name: Wagner
- first_name: Chao
full_name: Chen, Chao
id: 3E92416E-F248-11E8-B48F-1D18A9856A87
last_name: Chen
- first_name: Erald
full_name: Vuçini, Erald
last_name: Vuçini
citation:
ama: 'Wagner H, Chen C, Vuçini E. Efficient computation of persistent homology for
cubical data. In: Peikert R, Hauser H, Carr H, Fuchs R, eds. Topological Methods
in Data Analysis and Visualization II. Springer; 2011:91-106. doi:10.1007/978-3-642-23175-9_7'
apa: Wagner, H., Chen, C., & Vuçini, E. (2011). Efficient computation of persistent
homology for cubical data. In R. Peikert, H. Hauser, H. Carr, & R. Fuchs (Eds.),
Topological Methods in Data Analysis and Visualization II (pp. 91–106).
Springer. https://doi.org/10.1007/978-3-642-23175-9_7
chicago: Wagner, Hubert, Chao Chen, and Erald Vuçini. “Efficient Computation of
Persistent Homology for Cubical Data.” In Topological Methods in Data Analysis
and Visualization II, edited by Ronald Peikert, Helwig Hauser, Hamish Carr,
and Raphael Fuchs, 91–106. Springer, 2011. https://doi.org/10.1007/978-3-642-23175-9_7.
ieee: H. Wagner, C. Chen, and E. Vuçini, “Efficient computation of persistent homology
for cubical data,” in Topological Methods in Data Analysis and Visualization
II, R. Peikert, H. Hauser, H. Carr, and R. Fuchs, Eds. Springer, 2011, pp.
91–106.
ista: 'Wagner H, Chen C, Vuçini E. 2011.Efficient computation of persistent homology
for cubical data. In: Topological Methods in Data Analysis and Visualization II.
Theory, Algorithms, and Applications, , 91–106.'
mla: Wagner, Hubert, et al. “Efficient Computation of Persistent Homology for Cubical
Data.” Topological Methods in Data Analysis and Visualization II, edited
by Ronald Peikert et al., Springer, 2011, pp. 91–106, doi:10.1007/978-3-642-23175-9_7.
short: H. Wagner, C. Chen, E. Vuçini, in:, R. Peikert, H. Hauser, H. Carr, R. Fuchs
(Eds.), Topological Methods in Data Analysis and Visualization II, Springer, 2011,
pp. 91–106.
date_created: 2018-12-11T12:02:23Z
date_published: 2011-11-14T00:00:00Z
date_updated: 2021-01-12T07:42:18Z
day: '14'
department:
- _id: HeEd
doi: 10.1007/978-3-642-23175-9_7
editor:
- first_name: Ronald
full_name: Peikert, Ronald
last_name: Peikert
- first_name: Helwig
full_name: Hauser, Helwig
last_name: Hauser
- first_name: Hamish
full_name: Carr, Hamish
last_name: Carr
- first_name: Raphael
full_name: Fuchs, Raphael
last_name: Fuchs
language:
- iso: eng
month: '11'
oa_version: None
page: 91 - 106
publication: Topological Methods in Data Analysis and Visualization II
publication_status: published
publisher: Springer
publist_id: '3375'
quality_controlled: '1'
scopus_import: 1
status: public
title: Efficient computation of persistent homology for cubical data
type: book_chapter
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3273'
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Jean-Léon
full_name: Maître, Jean-Léon
id: 48F1E0D8-F248-11E8-B48F-1D18A9856A87
last_name: Maître
orcid: 0000-0002-3688-1474
citation:
ama: Maître J-L. Mechanics of adhesion and de‐adhesion in zebrafish germ layer progenitors.
2011.
apa: Maître, J.-L. (2011). Mechanics of adhesion and de‐adhesion in zebrafish
germ layer progenitors. Institute of Science and Technology Austria.
chicago: Maître, Jean-Léon. “Mechanics of Adhesion and De‐adhesion in Zebrafish
Germ Layer Progenitors.” Institute of Science and Technology Austria, 2011.
ieee: J.-L. Maître, “Mechanics of adhesion and de‐adhesion in zebrafish germ layer
progenitors,” Institute of Science and Technology Austria, 2011.
ista: Maître J-L. 2011. Mechanics of adhesion and de‐adhesion in zebrafish germ
layer progenitors. Institute of Science and Technology Austria.
mla: Maître, Jean-Léon. Mechanics of Adhesion and De‐adhesion in Zebrafish Germ
Layer Progenitors. Institute of Science and Technology Austria, 2011.
short: J.-L. Maître, Mechanics of Adhesion and De‐adhesion in Zebrafish Germ Layer
Progenitors, Institute of Science and Technology Austria, 2011.
date_created: 2018-12-11T12:02:23Z
date_published: 2011-12-12T00:00:00Z
date_updated: 2023-09-07T11:30:16Z
day: '12'
degree_awarded: PhD
department:
- _id: CaHe
language:
- iso: eng
month: '12'
oa_version: None
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '3373'
status: public
supervisor:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
title: Mechanics of adhesion and de‐adhesion in zebrafish germ layer progenitors
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2011'
...
---
_id: '3275'
abstract:
- lang: eng
text: 'Chemokines organize immune cell trafficking by inducing either directed (tactic)
or random (kinetic) migration and by activating integrins in order to support
surface adhesion (haptic). Beyond that the same chemokines can establish clearly
defined functional areas in secondary lymphoid organs. Until now it is unclear
how chemokines can fulfill such diverse functions. One decisive prerequisite to
explain these capacities is to know how chemokines are presented in tissue. In
theory chemokines could occur either soluble or immobilized, and could be distributed
either homogenously or as a concentration gradient. To dissect if and how the
presenting mode of chemokines influences immune cells, I tested the response of
dendritic cells (DCs) to differentially displayed chemokines. DCs are antigen
presenting cells that reside in the periphery and migrate into draining lymph
nodes (LNs) once exposed to inflammatory stimuli to activate naïve T cells. DCs
are guided to and within the LN by the chemokine receptor CCR7, which has two
ligands, the chemokines CCL19 and CCL21. Both CCR7 ligands are expressed by fibroblastic
reticular cells in the LN, but differ in their ability to bind to heparan sulfate
residues. CCL21 has a highly charged C-terminal extension, which mediates binding
to anionic surfaces, whereas CCL19 is lacking such residues and likely distributes
as a soluble molecule. This study shows that surface-bound CCL21 causes random,
haptokinetic DC motility, which is confined to the chemokine coated area by insideout
activation of β2 integrins that mediate cell binding to the surface. CCL19 on
the other hand forms concentration gradients which trigger directional, chemotactic
movement, but no surface adhesion. In addition DCs can actively manipulate this
system by recruiting and activating serine proteases on their surfaces, which
create - by proteolytically removing the adhesive C-terminus - a solubilized variant
of CCL21 that functionally resembles CCL19. By generating a CCL21 concentration
gradient DCs establish a positive feedback loop to recruit further DCs from the
periphery to the CCL21 coated region. In addition DCs can sense chemotactic gradients
as well as immobilized haptokinetic fields at the same time and integrate these
signals. The result is chemotactically biased haptokinesis - directional migration
confined to a chemokine coated track or area - which could explain the dynamic
but spatially tightly controlled swarming leukocyte locomotion patterns that have
been observed in lymphatic organs by intravital microscopists. The finding that
DCs can approach soluble cues in a non-adhesive manner while they attach to surfaces
coated with immobilized cues raises the question how these cells transmit intracellular
forces to the environment, especially in the non-adherent migration mode. In order
to migrate, cells have to generate and transmit force to the extracellular substrate.
Force transmission is the prerequisite to procure an expansion of the leading
edge and a forward motion of the whole cell body. In the current conceptions actin
polymerization at the leading edge is coupled to extracellular ligands via the
integrin family of transmembrane receptors, which allows the transmission of intracellular
force. Against the paradigm of force transmission during migration, leukocytes,
like DCs, are able to migrate in threedimensional environments without using integrin
transmembrane receptors (Lämmermann et al., 2008). This reflects the biological
function of leukocytes, as they can invade almost all tissues, whereby their migration
has to be independent from the extracellular environment. How the cells can achieve
this is unclear. For this study I examined DC migration in a defined threedimensional
environment and highlighted actin-dynamics with the probe Lifeact-GFP. The result
was that chemotactic DCs can switch between integrin-dependent and integrin- independent
locomotion and can thereby adapt to the adhesive properties of their environment.
If the cells are able to couple their actin cytoskeleton to the substrate, actin
polymerization is entirely converted into protrusion. Without coupling the actin
cortex undergoes slippage and retrograde actin flow can be observed. But retrograde
actin flow can be completely compensated by higher actin polymerization rate keeping
the migration velocity and the shape of the cells unaltered. Mesenchymal cells
like fibroblast cannot balance the loss of adhesive interaction, cannot protrude
into open space and, therefore, strictly depend on integrinmediated force coupling.
This leukocyte specific phenomenon of “adaptive force transmission” endows these
cells with the unique ability to transit and invade almost every type of tissue. '
acknowledgement: "I would like to express my sincere gratitude to the following people
who made with their continuous support and encouragement this thesis possible: First,
I want to thank Prof. Dr. Michael Sixt for his excellent supervision and mentoring,
especially for the nice, relaxed working atmosphere, a lot of brilliant ideas and
the freedom to work in my own way.\r\n\r\nProf. Dr. Reinhard Fässler for his constant
support of the Sixt lab and for providing excellent working conditions. \r\n\r\nProf.
Dr. Sanjiv Luther and Prof. Dr. Tobias Bollenbach for agreeing to be member of my
thesis committee and to evaluate my work.\r\n\r\nDr. Walther Göhring, Carmen Schmitz,
the Recombinant Protein Production core facility and the animal care takers for
providing the “infrastructure” for this thesis. \r\n\r\nProf. Dr. Daniel Legler,
Markus Bruckner and Dr. Julien Polleux for very fruitful collaborations and discussions.\r\n\r\nMy
labmates for their help, a lot of discussions and to make the Sixt lab to a convenient
place to work : Karin Hirsch, Tim Lämmeramnn, Holger Pflicke, Jörg Renkawitz, Michele
Weber and Alexander Eichner All members of the Department of Molecular Medicine
for their help. Especially I want to thank Sarah Schmidt, Karin Hirsch and Raphael
Ruppert for their friendship, nice chats and their uncensored point of view. "
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Kathrin
full_name: Schumann, Kathrin
id: F44D762E-4F9D-11E9-B64C-9EB26CEFFB5F
last_name: Schumann
citation:
ama: Schumann K. The role of chemotactic gradients in dendritic cell migration.
2011.
apa: Schumann, K. (2011). The role of chemotactic gradients in dendritic cell
migration. Institute of Science and Technology Austria.
chicago: Schumann, Kathrin. “The Role of Chemotactic Gradients in Dendritic Cell
Migration.” Institute of Science and Technology Austria, 2011.
ieee: K. Schumann, “The role of chemotactic gradients in dendritic cell migration,”
Institute of Science and Technology Austria, 2011.
ista: Schumann K. 2011. The role of chemotactic gradients in dendritic cell migration.
Institute of Science and Technology Austria.
mla: Schumann, Kathrin. The Role of Chemotactic Gradients in Dendritic Cell Migration.
Institute of Science and Technology Austria, 2011.
short: K. Schumann, The Role of Chemotactic Gradients in Dendritic Cell Migration,
Institute of Science and Technology Austria, 2011.
date_created: 2018-12-11T12:02:24Z
date_published: 2011-03-01T00:00:00Z
date_updated: 2023-09-07T11:31:48Z
day: '01'
ddc:
- '570'
- '579'
degree_awarded: PhD
department:
- _id: MiSi
file:
- access_level: closed
checksum: e69eee6252660f0b694a2ea8923ddc72
content_type: application/pdf
creator: dernst
date_created: 2019-03-26T08:12:21Z
date_updated: 2020-07-14T12:46:06Z
file_id: '6177'
file_name: 2011_Thesis_Kathrin_Schumann.pdf
file_size: 4487708
relation: main_file
- access_level: open_access
checksum: 71727d63f424b5b446f68f4b87ecadc0
content_type: application/pdf
creator: dernst
date_created: 2021-02-22T11:24:30Z
date_updated: 2021-02-22T11:24:30Z
file_id: '9175'
file_name: 2011_Thesis_Schumann_noS.pdf
file_size: 4313127
relation: main_file
success: 1
file_date_updated: 2021-02-22T11:24:30Z
has_accepted_license: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: '141'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '3371'
pubrep_id: '11'
status: public
supervisor:
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
title: The role of chemotactic gradients in dendritic cell migration
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2011'
...
---
_id: '3287'
abstract:
- lang: eng
text: 'Diffusing membrane constituents are constantly exposed to a variety of forces
that influence their stochastic path. Single molecule experiments allow for resolving
trajectories at extremely high spatial and temporal accuracy, thereby offering
insights into en route interactions of the tracer. In this review we discuss approaches
to derive information about the underlying processes, based on single molecule
tracking experiments. In particular, we focus on a new versatile way to analyze
single molecule diffusion in the absence of a full analytical treatment. The method
is based on comprehensive comparison of an experimental data set against the hypothetical
outcome of multiple experiments performed on the computer. Since Monte Carlo simulations
can be easily and rapidly performed even on state-of-the-art PCs, our method provides
a simple way for testing various - even complicated - diffusion models. We describe
the new method in detail, and show the applicability on two specific examples:
firstly, kinetic rate constants can be derived for the transient interaction of
mobile membrane proteins; secondly, residence time and corral size can be extracted
for confined diffusion.'
author:
- first_name: Verena
full_name: Ruprecht, Verena
id: 4D71A03A-F248-11E8-B48F-1D18A9856A87
last_name: Ruprecht
orcid: 0000-0003-4088-8633
- first_name: Markus
full_name: Axmann, Markus
last_name: Axmann
- first_name: Stefan
full_name: Wieser, Stefan
id: 355AA5A0-F248-11E8-B48F-1D18A9856A87
last_name: Wieser
orcid: 0000-0002-2670-2217
- first_name: Gerhard
full_name: Schuetz, Gerhard
last_name: Schuetz
citation:
ama: Ruprecht V, Axmann M, Wieser S, Schuetz G. What can we learn from single molecule
trajectories? Current Protein & Peptide Science. 2011;12(8):714-724.
doi:10.2174/138920311798841753
apa: Ruprecht, V., Axmann, M., Wieser, S., & Schuetz, G. (2011). What can we
learn from single molecule trajectories? Current Protein & Peptide Science.
Bentham Science Publishers. https://doi.org/10.2174/138920311798841753
chicago: Ruprecht, Verena, Markus Axmann, Stefan Wieser, and Gerhard Schuetz. “What
Can We Learn from Single Molecule Trajectories?” Current Protein & Peptide
Science. Bentham Science Publishers, 2011. https://doi.org/10.2174/138920311798841753.
ieee: V. Ruprecht, M. Axmann, S. Wieser, and G. Schuetz, “What can we learn from
single molecule trajectories?,” Current Protein & Peptide Science,
vol. 12, no. 8. Bentham Science Publishers, pp. 714–724, 2011.
ista: Ruprecht V, Axmann M, Wieser S, Schuetz G. 2011. What can we learn from single
molecule trajectories? Current Protein & Peptide Science. 12(8), 714–724.
mla: Ruprecht, Verena, et al. “What Can We Learn from Single Molecule Trajectories?”
Current Protein & Peptide Science, vol. 12, no. 8, Bentham Science
Publishers, 2011, pp. 714–24, doi:10.2174/138920311798841753.
short: V. Ruprecht, M. Axmann, S. Wieser, G. Schuetz, Current Protein & Peptide
Science 12 (2011) 714–724.
date_created: 2018-12-11T12:02:28Z
date_published: 2011-12-01T00:00:00Z
date_updated: 2021-01-12T07:42:24Z
day: '01'
department:
- _id: CaHe
- _id: MiSi
doi: 10.2174/138920311798841753
intvolume: ' 12'
issue: '8'
language:
- iso: eng
month: '12'
oa_version: None
page: 714 - 724
publication: Current Protein & Peptide Science
publication_status: published
publisher: Bentham Science Publishers
publist_id: '3358'
quality_controlled: '1'
scopus_import: 1
status: public
title: What can we learn from single molecule trajectories?
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2011'
...
---
_id: '3288'
abstract:
- lang: eng
text: 'The zonula adherens (ZA) of epithelial cells is a site of cell-cell adhesion
where cellular forces are exerted and resisted. Increasing evidence indicates
that E-cadherin adhesion molecules at the ZA serve to sense force applied on the
junctions and coordinate cytoskeletal responses to those forces. Efforts to understand
the role that cadherins play in mechanotransduction have been limited by the lack
of assays to measure the impact of forces on the ZA. In this study we used 4D
imaging of GFP-tagged E-cadherin to analyse the movement of the ZA. Junctions
in confluent epithelial monolayers displayed prominent movements oriented orthogonal
(perpendicular) to the ZA itself. Two components were identified in these movements:
a relatively slow unidirectional (translational) component that could be readily
fitted by least-squares regression analysis, upon which were superimposed more
rapid oscillatory movements. Myosin IIB was a dominant factor responsible for
driving the unilateral translational movements. In contrast, frequency spectrum
analysis revealed that depletion of Myosin IIA increased the power of the oscillatory
movements. This implies that Myosin IIA may serve to dampen oscillatory movements
of the ZA. This extends our recent analysis of Myosin II at the ZA to demonstrate
that Myosin IIA and Myosin IIB make distinct contributions to junctional movement
at the ZA.'
acknowledgement: his work was funded by the National Health and Medical Research Council
(NHMRC) of Australia. M.S. was an Erwin Schroedinger postdoctoral fellow of the
Austrian Science Fund (FWF), S.K.W. is supported by a UQ International Research
Tuition Award and Research Scholarship, S.M .by an ANZ Trustees PhD Scholarship.
A.S.Y. is a Research Fellow of the NHMRC. Confocal imaging was performed at the
Australian Cancer Research Foundation (ACRF) Cancer Biology Imaging Centre at the
Institute for Molecular Bioscience, established with the generous support of the
ACRF.
author:
- first_name: Michael
full_name: Smutny, Michael
id: 3FE6E4E8-F248-11E8-B48F-1D18A9856A87
last_name: Smutny
orcid: 0000-0002-5920-9090
- first_name: Selwin
full_name: Wu, Selwin
last_name: Wu
- first_name: Guillermo
full_name: Gomez, Guillermo
last_name: Gomez
- first_name: Sabine
full_name: Mangold, Sabine
last_name: Mangold
- first_name: Alpha
full_name: Yap, Alpha
last_name: Yap
- first_name: Nicholas
full_name: Hamilton, Nicholas
last_name: Hamilton
citation:
ama: Smutny M, Wu S, Gomez G, Mangold S, Yap A, Hamilton N. Multicomponent analysis
of junctional movements regulated by Myosin II isoforms at the epithelial zonula
adherens. PLoS One. 2011;6(7). doi:10.1371/journal.pone.0022458
apa: Smutny, M., Wu, S., Gomez, G., Mangold, S., Yap, A., & Hamilton, N. (2011).
Multicomponent analysis of junctional movements regulated by Myosin II isoforms
at the epithelial zonula adherens. PLoS One. Public Library of Science.
https://doi.org/10.1371/journal.pone.0022458
chicago: Smutny, Michael, Selwin Wu, Guillermo Gomez, Sabine Mangold, Alpha Yap,
and Nicholas Hamilton. “Multicomponent Analysis of Junctional Movements Regulated
by Myosin II Isoforms at the Epithelial Zonula Adherens.” PLoS One. Public
Library of Science, 2011. https://doi.org/10.1371/journal.pone.0022458.
ieee: M. Smutny, S. Wu, G. Gomez, S. Mangold, A. Yap, and N. Hamilton, “Multicomponent
analysis of junctional movements regulated by Myosin II isoforms at the epithelial
zonula adherens,” PLoS One, vol. 6, no. 7. Public Library of Science, 2011.
ista: Smutny M, Wu S, Gomez G, Mangold S, Yap A, Hamilton N. 2011. Multicomponent
analysis of junctional movements regulated by Myosin II isoforms at the epithelial
zonula adherens. PLoS One. 6(7).
mla: Smutny, Michael, et al. “Multicomponent Analysis of Junctional Movements Regulated
by Myosin II Isoforms at the Epithelial Zonula Adherens.” PLoS One, vol.
6, no. 7, Public Library of Science, 2011, doi:10.1371/journal.pone.0022458.
short: M. Smutny, S. Wu, G. Gomez, S. Mangold, A. Yap, N. Hamilton, PLoS One 6 (2011).
date_created: 2018-12-11T12:02:28Z
date_published: 2011-07-22T00:00:00Z
date_updated: 2021-01-12T07:42:25Z
day: '22'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1371/journal.pone.0022458
file:
- access_level: open_access
checksum: 57a5eb11dd05241c48c44f492b3ec3ac
content_type: application/pdf
creator: dernst
date_created: 2019-05-10T10:51:43Z
date_updated: 2020-07-14T12:46:06Z
file_id: '6399'
file_name: 2011_PLOS_Smutny.PDF
file_size: 1984567
relation: main_file
file_date_updated: 2020-07-14T12:46:06Z
has_accepted_license: '1'
intvolume: ' 6'
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '3357'
quality_controlled: '1'
status: public
title: Multicomponent analysis of junctional movements regulated by Myosin II isoforms
at the epithelial zonula adherens
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2011'
...
---
_id: '3290'
abstract:
- lang: eng
text: 'Analysis of genomic data requires an efficient way to calculate likelihoods
across very large numbers of loci. We describe a general method for finding the
distribution of genealogies: we allow migration between demes, splitting of demes
[as in the isolation-with-migration (IM) model], and recombination between linked
loci. These processes are described by a set of linear recursions for the generating
function of branch lengths. Under the infinite-sites model, the probability of
any configuration of mutations can be found by differentiating this generating
function. Such calculations are feasible for small numbers of sampled genomes:
as an example, we show how the generating function can be derived explicitly for
three genes under the two-deme IM model. This derivation is done automatically,
using Mathematica. Given data from a large number of unlinked and nonrecombining
blocks of sequence, these results can be used to find maximum-likelihood estimates
of model parameters by tabulating the probabilities of all relevant mutational
configurations and then multiplying across loci. The feasibility of the method
is demonstrated by applying it to simulated data and to a data set previously
analyzed by Wang and Hey (2010) consisting of 26,141 loci sampled from Drosophila
simulans and D. melanogaster. Our results suggest that such likelihood calculations
are scalable to genomic data as long as the numbers of sampled individuals and
mutations per sequence block are small.'
author:
- first_name: Konrad
full_name: Lohse, Konrad
last_name: Lohse
- first_name: Richard
full_name: Harrison, Richard
last_name: Harrison
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Lohse K, Harrison R, Barton NH. A general method for calculating likelihoods
under the coalescent process. Genetics. 2011;189(3):977-987. doi:10.1534/genetics.111.129569
apa: Lohse, K., Harrison, R., & Barton, N. H. (2011). A general method for calculating
likelihoods under the coalescent process. Genetics. Genetics Society of
America. https://doi.org/10.1534/genetics.111.129569
chicago: Lohse, Konrad, Richard Harrison, and Nicholas H Barton. “A General Method
for Calculating Likelihoods under the Coalescent Process.” Genetics. Genetics
Society of America, 2011. https://doi.org/10.1534/genetics.111.129569.
ieee: K. Lohse, R. Harrison, and N. H. Barton, “A general method for calculating
likelihoods under the coalescent process,” Genetics, vol. 189, no. 3. Genetics
Society of America, pp. 977–987, 2011.
ista: Lohse K, Harrison R, Barton NH. 2011. A general method for calculating likelihoods
under the coalescent process. Genetics. 189(3), 977–987.
mla: Lohse, Konrad, et al. “A General Method for Calculating Likelihoods under the
Coalescent Process.” Genetics, vol. 189, no. 3, Genetics Society of America,
2011, pp. 977–87, doi:10.1534/genetics.111.129569.
short: K. Lohse, R. Harrison, N.H. Barton, Genetics 189 (2011) 977–987.
date_created: 2018-12-11T12:02:29Z
date_published: 2011-11-01T00:00:00Z
date_updated: 2021-01-12T07:42:26Z
day: '01'
department:
- _id: NiBa
doi: 10.1534/genetics.111.129569
ec_funded: 1
intvolume: ' 189'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213358/
month: '11'
oa: 1
oa_version: Submitted Version
page: 977 - 987
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
publication: Genetics
publication_status: published
publisher: Genetics Society of America
publist_id: '3355'
quality_controlled: '1'
scopus_import: 1
status: public
title: A general method for calculating likelihoods under the coalescent process
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 189
year: '2011'
...