---
_id: '12198'
abstract:
- lang: eng
  text: The Arabidopsis thaliana central cell, the companion cell of the egg, undergoes
    DNA demethylation before fertilization, but the targeting preferences, mechanism,
    and biological significance of this process remain unclear. Here, we show that
    active DNA demethylation mediated by the DEMETER DNA glycosylase accounts for
    all of the demethylation in the central cell and preferentially targets small,
    AT-rich, and nucleosome-depleted euchromatic transposable elements. The vegetative
    cell, the companion cell of sperm, also undergoes DEMETER-dependent demethylation
    of similar sequences, and lack of DEMETER in vegetative cells causes reduced small
    RNA–directed DNA methylation of transposons in sperm. Our results demonstrate
    that demethylation in companion cells reinforces transposon methylation in plant
    gametes and likely contributes to stable silencing of transposable elements across
    generations.
acknowledgement: We thank S. Harmer for assistance with the analysis of histone modifications,
  the BioOptics team at the Vienna Biocenter Campus for sorting sperm and vegetative
  cell nuclei, K. Slotkin for the LAT52p-amiRNA=GFP plasmid, and G. Drews for the
  DD45p-GFP transgenic line. This work was partially funded by an NIH grant (GM69415)
  to R.L.F., NSF grants (MCB-0918821 and IOS-1025890) to R.L.F. and D.Z., a Young
  Investigator Grant from the Arnold and Mabel Beckman Foundation to D.Z., an Austrian
  Science Fund (FWF) grant P21389-B03 to H.T., a Ruth L. Kirschstein NIH Predoctoral
  Fellowship (GM093633) to C.A.I., a Fulbright Scholarship to J.A.R., a fellowship
  from the Jane Coffin Childs Memorial Fund to A.Z., and a Robert and Colleen Haas
  Scholarship to D.R. Sequencing data are deposited in GEO (GSE38935).
article_processing_charge: No
article_type: original
author:
- first_name: Christian A.
  full_name: Ibarra, Christian A.
  last_name: Ibarra
- first_name: Xiaoqi
  full_name: Feng, Xiaoqi
  id: e0164712-22ee-11ed-b12a-d80fcdf35958
  last_name: Feng
  orcid: 0000-0002-4008-1234
- first_name: Vera K.
  full_name: Schoft, Vera K.
  last_name: Schoft
- first_name: Tzung-Fu
  full_name: Hsieh, Tzung-Fu
  last_name: Hsieh
- first_name: Rie
  full_name: Uzawa, Rie
  last_name: Uzawa
- first_name: Jessica A.
  full_name: Rodrigues, Jessica A.
  last_name: Rodrigues
- first_name: Assaf
  full_name: Zemach, Assaf
  last_name: Zemach
- first_name: Nina
  full_name: Chumak, Nina
  last_name: Chumak
- first_name: Adriana
  full_name: Machlicova, Adriana
  last_name: Machlicova
- first_name: Toshiro
  full_name: Nishimura, Toshiro
  last_name: Nishimura
- first_name: Denisse
  full_name: Rojas, Denisse
  last_name: Rojas
- first_name: Robert L.
  full_name: Fischer, Robert L.
  last_name: Fischer
- first_name: Hisashi
  full_name: Tamaru, Hisashi
  last_name: Tamaru
- first_name: Daniel
  full_name: Zilberman, Daniel
  last_name: Zilberman
citation:
  ama: Ibarra CA, Feng X, Schoft VK, et al. Active DNA demethylation in plant companion
    cells reinforces transposon methylation in gametes. <i>Science</i>. 2012;337(6100):1360-1364.
    doi:<a href="https://doi.org/10.1126/science.1224839">10.1126/science.1224839</a>
  apa: Ibarra, C. A., Feng, X., Schoft, V. K., Hsieh, T.-F., Uzawa, R., Rodrigues,
    J. A., … Zilberman, D. (2012). Active DNA demethylation in plant companion cells
    reinforces transposon methylation in gametes. <i>Science</i>. American Association
    for the Advancement of Science. <a href="https://doi.org/10.1126/science.1224839">https://doi.org/10.1126/science.1224839</a>
  chicago: Ibarra, Christian A., Xiaoqi Feng, Vera K. Schoft, Tzung-Fu Hsieh, Rie
    Uzawa, Jessica A. Rodrigues, Assaf Zemach, et al. “Active DNA Demethylation in
    Plant Companion Cells Reinforces Transposon Methylation in Gametes.” <i>Science</i>.
    American Association for the Advancement of Science, 2012. <a href="https://doi.org/10.1126/science.1224839">https://doi.org/10.1126/science.1224839</a>.
  ieee: C. A. Ibarra <i>et al.</i>, “Active DNA demethylation in plant companion cells
    reinforces transposon methylation in gametes,” <i>Science</i>, vol. 337, no. 6100.
    American Association for the Advancement of Science, pp. 1360–1364, 2012.
  ista: Ibarra CA, Feng X, Schoft VK, Hsieh T-F, Uzawa R, Rodrigues JA, Zemach A,
    Chumak N, Machlicova A, Nishimura T, Rojas D, Fischer RL, Tamaru H, Zilberman
    D. 2012. Active DNA demethylation in plant companion cells reinforces transposon
    methylation in gametes. Science. 337(6100), 1360–1364.
  mla: Ibarra, Christian A., et al. “Active DNA Demethylation in Plant Companion Cells
    Reinforces Transposon Methylation in Gametes.” <i>Science</i>, vol. 337, no. 6100,
    American Association for the Advancement of Science, 2012, pp. 1360–64, doi:<a
    href="https://doi.org/10.1126/science.1224839">10.1126/science.1224839</a>.
  short: C.A. Ibarra, X. Feng, V.K. Schoft, T.-F. Hsieh, R. Uzawa, J.A. Rodrigues,
    A. Zemach, N. Chumak, A. Machlicova, T. Nishimura, D. Rojas, R.L. Fischer, H.
    Tamaru, D. Zilberman, Science 337 (2012) 1360–1364.
date_created: 2023-01-16T09:21:24Z
date_published: 2012-09-14T00:00:00Z
date_updated: 2023-10-16T09:27:26Z
day: '14'
department:
- _id: XiFe
doi: 10.1126/science.1224839
external_id:
  pmid:
  - '22984074'
intvolume: '       337'
issue: '6100'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034762/
month: '09'
oa: 1
oa_version: Published Version
page: 1360-1364
pmid: 1
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
  issn:
  - 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Active DNA demethylation in plant companion cells reinforces transposon methylation
  in gametes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 337
year: '2012'
...
---
_id: '9755'
abstract:
- lang: eng
  text: Due to the omnipresent risk of epidemics, insect societies have evolved sophisticated
    disease defences at the individual and colony level. An intriguing yet little
    understood phenomenon is that social contact to pathogen-exposed individuals reduces
    susceptibility of previously naive nestmates to this pathogen. We tested whether
    such social immunisation in Lasius ants against the entomopathogenic fungus Metarhizium
    anisopliae is based on active upregulation of the immune system of nestmates following
    contact to an infectious individual or passive protection via transfer of immune
    effectors among group members—that is, active versus passive immunisation. We
    found no evidence for involvement of passive immunisation via transfer of antimicrobials
    among colony members. Instead, intensive allogrooming behaviour between naive
    and pathogen-exposed ants before fungal conidia firmly attached to their cuticle
    suggested passage of the pathogen from the exposed individuals to their nestmates.
    By tracing fluorescence-labelled conidia we indeed detected frequent pathogen
    transfer to the nestmates, where they caused low-level infections as revealed
    by growth of small numbers of fungal colony forming units from their dissected
    body content. These infections rarely led to death, but instead promoted an enhanced
    ability to inhibit fungal growth and an active upregulation of immune genes involved
    in antifungal defences (defensin and prophenoloxidase, PPO). Contrarily, there
    was no upregulation of the gene cathepsin L, which is associated with antibacterial
    and antiviral defences, and we found no increased antibacterial activity of nestmates
    of fungus-exposed ants. This indicates that social immunisation after fungal exposure
    is specific, similar to recent findings for individual-level immune priming in
    invertebrates. Epidemiological modeling further suggests that active social immunisation
    is adaptive, as it leads to faster elimination of the disease and lower death
    rates than passive immunisation. Interestingly, humans have also utilised the
    protective effect of low-level infections to fight smallpox by intentional transfer
    of low pathogen doses (“variolation” or “inoculation”).
article_processing_charge: No
author:
- first_name: Matthias
  full_name: Konrad, Matthias
  id: 46528076-F248-11E8-B48F-1D18A9856A87
  last_name: Konrad
- first_name: Meghan
  full_name: Vyleta, Meghan
  id: 418901AA-F248-11E8-B48F-1D18A9856A87
  last_name: Vyleta
- first_name: Fabian
  full_name: Theis, Fabian
  last_name: Theis
- first_name: Miriam
  full_name: Stock, Miriam
  id: 42462816-F248-11E8-B48F-1D18A9856A87
  last_name: Stock
- first_name: Martina
  full_name: Klatt, Martina
  id: E60F29C6-E9AE-11E9-AF6E-D190C7302F38
  last_name: Klatt
- first_name: Verena
  full_name: Drescher, Verena
  last_name: Drescher
- first_name: Carsten
  full_name: Marr, Carsten
  last_name: Marr
- first_name: Line V
  full_name: Ugelvig, Line V
  id: 3DC97C8E-F248-11E8-B48F-1D18A9856A87
  last_name: Ugelvig
  orcid: 0000-0003-1832-8883
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
citation:
  ama: 'Konrad M, Vyleta M, Theis F, et al. Data from: Social transfer of pathogenic
    fungus promotes active immunisation in ant colonies. 2012. doi:<a href="https://doi.org/10.5061/dryad.sv37s">10.5061/dryad.sv37s</a>'
  apa: 'Konrad, M., Vyleta, M., Theis, F., Stock, M., Klatt, M., Drescher, V., … Cremer,
    S. (2012). Data from: Social transfer of pathogenic fungus promotes active immunisation
    in ant colonies. Dryad. <a href="https://doi.org/10.5061/dryad.sv37s">https://doi.org/10.5061/dryad.sv37s</a>'
  chicago: 'Konrad, Matthias, Meghan Vyleta, Fabian Theis, Miriam Stock, Martina Klatt,
    Verena Drescher, Carsten Marr, Line V Ugelvig, and Sylvia Cremer. “Data from:
    Social Transfer of Pathogenic Fungus Promotes Active Immunisation in Ant Colonies.”
    Dryad, 2012. <a href="https://doi.org/10.5061/dryad.sv37s">https://doi.org/10.5061/dryad.sv37s</a>.'
  ieee: 'M. Konrad <i>et al.</i>, “Data from: Social transfer of pathogenic fungus
    promotes active immunisation in ant colonies.” Dryad, 2012.'
  ista: 'Konrad M, Vyleta M, Theis F, Stock M, Klatt M, Drescher V, Marr C, Ugelvig
    LV, Cremer S. 2012. Data from: Social transfer of pathogenic fungus promotes active
    immunisation in ant colonies, Dryad, <a href="https://doi.org/10.5061/dryad.sv37s">10.5061/dryad.sv37s</a>.'
  mla: 'Konrad, Matthias, et al. <i>Data from: Social Transfer of Pathogenic Fungus
    Promotes Active Immunisation in Ant Colonies</i>. Dryad, 2012, doi:<a href="https://doi.org/10.5061/dryad.sv37s">10.5061/dryad.sv37s</a>.'
  short: M. Konrad, M. Vyleta, F. Theis, M. Stock, M. Klatt, V. Drescher, C. Marr,
    L.V. Ugelvig, S. Cremer, (2012).
date_created: 2021-07-30T08:39:13Z
date_published: 2012-09-27T00:00:00Z
date_updated: 2023-02-23T11:18:41Z
day: '27'
department:
- _id: SyCr
doi: 10.5061/dryad.sv37s
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.sv37s
month: '09'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '3242'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Social transfer of pathogenic fungus promotes active immunisation
  in ant colonies'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2012'
...
---
_id: '9757'
abstract:
- lang: eng
  text: To fight infectious diseases, host immune defences are employed at multiple
    levels. Sanitary behaviour, such as pathogen avoidance and removal, acts as a
    first line of defence to prevent infection [1] before activation of the physiological
    immune system. Insect societies have evolved a wide range of collective hygiene
    measures and intensive health care towards pathogen-exposed group members [2].
    One of the most common behaviours is allogrooming, in which nestmates remove infectious
    particles from the body surfaces of exposed individuals [3]. Here we show that,
    in invasive garden ants, grooming of fungus-exposed brood is effective beyond
    the sheer mechanical removal of fungal conidiospores as it also includes chemical
    disinfection through the application of poison produced by the ants themselves.
    Formic acid is the main active component of the poison. It inhibits fungal growth
    of conidiospores remaining on the brood surface after grooming and also those
    collected in the mouth of the grooming ant. This dual function is achieved by
    uptake of the poison droplet into the mouth through acidopore self-grooming and
    subsequent application onto the infectious brood via brood grooming. This extraordinary
    behaviour extends current understanding of grooming and the establishment of social
    immunity in insect societies.
article_processing_charge: No
author:
- first_name: Simon
  full_name: Tragust, Simon
  id: 35A7A418-F248-11E8-B48F-1D18A9856A87
  last_name: Tragust
- first_name: Barbara
  full_name: Mitteregger, Barbara
  id: 479DDAAC-E9CD-11E9-9B5F-82450873F7A1
  last_name: Mitteregger
- first_name: Vanessa
  full_name: Barone, Vanessa
  id: 419EECCC-F248-11E8-B48F-1D18A9856A87
  last_name: Barone
  orcid: 0000-0003-2676-3367
- first_name: Matthias
  full_name: Konrad, Matthias
  id: 46528076-F248-11E8-B48F-1D18A9856A87
  last_name: Konrad
- first_name: Line V
  full_name: Ugelvig, Line V
  id: 3DC97C8E-F248-11E8-B48F-1D18A9856A87
  last_name: Ugelvig
  orcid: 0000-0003-1832-8883
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
citation:
  ama: 'Tragust S, Mitteregger B, Barone V, Konrad M, Ugelvig LV, Cremer S. Data from:
    Ants disinfect fungus-exposed brood by oral uptake and spread of their poison.
    2012. doi:<a href="https://doi.org/10.5061/dryad.61649">10.5061/dryad.61649</a>'
  apa: 'Tragust, S., Mitteregger, B., Barone, V., Konrad, M., Ugelvig, L. V., &#38;
    Cremer, S. (2012). Data from: Ants disinfect fungus-exposed brood by oral uptake
    and spread of their poison. Dryad. <a href="https://doi.org/10.5061/dryad.61649">https://doi.org/10.5061/dryad.61649</a>'
  chicago: 'Tragust, Simon, Barbara Mitteregger, Vanessa Barone, Matthias Konrad,
    Line V Ugelvig, and Sylvia Cremer. “Data from: Ants Disinfect Fungus-Exposed Brood
    by Oral Uptake and Spread of Their Poison.” Dryad, 2012. <a href="https://doi.org/10.5061/dryad.61649">https://doi.org/10.5061/dryad.61649</a>.'
  ieee: 'S. Tragust, B. Mitteregger, V. Barone, M. Konrad, L. V. Ugelvig, and S. Cremer,
    “Data from: Ants disinfect fungus-exposed brood by oral uptake and spread of their
    poison.” Dryad, 2012.'
  ista: 'Tragust S, Mitteregger B, Barone V, Konrad M, Ugelvig LV, Cremer S. 2012.
    Data from: Ants disinfect fungus-exposed brood by oral uptake and spread of their
    poison, Dryad, <a href="https://doi.org/10.5061/dryad.61649">10.5061/dryad.61649</a>.'
  mla: 'Tragust, Simon, et al. <i>Data from: Ants Disinfect Fungus-Exposed Brood by
    Oral Uptake and Spread of Their Poison</i>. Dryad, 2012, doi:<a href="https://doi.org/10.5061/dryad.61649">10.5061/dryad.61649</a>.'
  short: S. Tragust, B. Mitteregger, V. Barone, M. Konrad, L.V. Ugelvig, S. Cremer,
    (2012).
date_created: 2021-07-30T12:31:31Z
date_published: 2012-12-14T00:00:00Z
date_updated: 2023-02-23T11:04:28Z
day: '14'
department:
- _id: SyCr
doi: 10.5061/dryad.61649
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.61649
month: '12'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '2926'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Ants disinfect fungus-exposed brood by oral uptake and spread of
  their poison'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2012'
...
---
_id: '9758'
abstract:
- lang: eng
  text: 'We propose a two-step procedure for estimating multiple migration rates in
    an approximate Bayesian computation (ABC) framework, accounting for global nuisance
    parameters. The approach is not limited to migration, but generally of interest
    for inference problems with multiple parameters and a modular structure (e.g.
    independent sets of demes or loci). We condition on a known, but complex demographic
    model of a spatially subdivided population, motivated by the reintroduction of
    Alpine ibex (Capra ibex) into Switzerland. In the first step, the global parameters
    ancestral mutation rate and male mating skew have been estimated for the whole
    population in Aeschbacher et al. (Genetics 2012; 192: 1027). In the second step,
    we estimate in this study the migration rates independently for clusters of demes
    putatively connected by migration. For large clusters (many migration rates),
    ABC faces the problem of too many summary statistics. We therefore assess by simulation
    if estimation per pair of demes is a valid alternative. We find that the trade-off
    between reduced dimensionality for the pairwise estimation on the one hand and
    lower accuracy due to the assumption of pairwise independence on the other depends
    on the number of migration rates to be inferred: the accuracy of the pairwise
    approach increases with the number of parameters, relative to the joint estimation
    approach. To distinguish between low and zero migration, we perform ABC-type model
    comparison between a model with migration and one without. Applying the approach
    to microsatellite data from Alpine ibex, we find no evidence for substantial gene
    flow via migration, except for one pair of demes in one direction.'
article_processing_charge: No
author:
- first_name: Simon
  full_name: Aeschbacher, Simon
  id: 2D35326E-F248-11E8-B48F-1D18A9856A87
  last_name: Aeschbacher
- first_name: Andreas
  full_name: Futschik, Andreas
  last_name: Futschik
- first_name: Mark
  full_name: Beaumont, Mark
  last_name: Beaumont
citation:
  ama: 'Aeschbacher S, Futschik A, Beaumont M. Data from: Approximate Bayesian computation
    for modular inference problems with many parameters: the example of migration
    rates. 2012. doi:<a href="https://doi.org/10.5061/dryad.274b1">10.5061/dryad.274b1</a>'
  apa: 'Aeschbacher, S., Futschik, A., &#38; Beaumont, M. (2012). Data from: Approximate
    Bayesian computation for modular inference problems with many parameters: the
    example of migration rates. Dryad. <a href="https://doi.org/10.5061/dryad.274b1">https://doi.org/10.5061/dryad.274b1</a>'
  chicago: 'Aeschbacher, Simon, Andreas Futschik, and Mark Beaumont. “Data from: Approximate
    Bayesian Computation for Modular Inference Problems with Many Parameters: The
    Example of Migration Rates.” Dryad, 2012. <a href="https://doi.org/10.5061/dryad.274b1">https://doi.org/10.5061/dryad.274b1</a>.'
  ieee: 'S. Aeschbacher, A. Futschik, and M. Beaumont, “Data from: Approximate Bayesian
    computation for modular inference problems with many parameters: the example of
    migration rates.” Dryad, 2012.'
  ista: 'Aeschbacher S, Futschik A, Beaumont M. 2012. Data from: Approximate Bayesian
    computation for modular inference problems with many parameters: the example of
    migration rates, Dryad, <a href="https://doi.org/10.5061/dryad.274b1">10.5061/dryad.274b1</a>.'
  mla: 'Aeschbacher, Simon, et al. <i>Data from: Approximate Bayesian Computation
    for Modular Inference Problems with Many Parameters: The Example of Migration
    Rates</i>. Dryad, 2012, doi:<a href="https://doi.org/10.5061/dryad.274b1">10.5061/dryad.274b1</a>.'
  short: S. Aeschbacher, A. Futschik, M. Beaumont, (2012).
date_created: 2021-07-30T12:36:39Z
date_published: 2012-11-14T00:00:00Z
date_updated: 2023-02-23T11:05:19Z
day: '14'
department:
- _id: NiBa
doi: 10.5061/dryad.274b1
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.274b1
month: '11'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '2944'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Approximate Bayesian computation for modular inference problems
  with many parameters: the example of migration rates'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2012'
...
---
_id: '3836'
abstract:
- lang: eng
  text: Hierarchical Timing Language (HTL) is a coordination language for distributed,
    hard real-time applications. HTL is a hierarchical extension of Giotto and, like
    its predecessor, based on the logical execution time (LET) paradigm of real-time
    programming. Giotto is compiled into code for a virtual machine, called the EmbeddedMachine
    (or E machine). If HTL is targeted to the E machine, then the hierarchicalprogram
    structure needs to be flattened; the flattening makes separatecompilation difficult,
    and may result in E machinecode of exponential size. In this paper, we propose
    a generalization of the E machine, which supports a hierarchicalprogram structure
    at runtime through real-time trigger mechanisms that are arranged in a tree. We
    present the generalized E machine, and a modular compiler for HTL that generates
    code of linear size. The compiler may generate code for any part of a given HTL
    program separately in any order.
author:
- first_name: Arkadeb
  full_name: Ghosal, Arkadeb
  last_name: Ghosal
- first_name: Daniel
  full_name: Iercan, Daniel
  last_name: Iercan
- first_name: Christoph
  full_name: Kirsch, Christoph
  last_name: Kirsch
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Alberto
  full_name: Sangiovanni Vincentelli, Alberto
  last_name: Sangiovanni Vincentelli
citation:
  ama: Ghosal A, Iercan D, Kirsch C, Henzinger TA, Sangiovanni Vincentelli A. Separate
    compilation of hierarchical real-time programs into linear-bounded embedded machine
    code. <i>Science of Computer Programming</i>. 2012;77(2):96-112. doi:<a href="https://doi.org/10.1016/j.scico.2010.06.004">10.1016/j.scico.2010.06.004</a>
  apa: Ghosal, A., Iercan, D., Kirsch, C., Henzinger, T. A., &#38; Sangiovanni Vincentelli,
    A. (2012). Separate compilation of hierarchical real-time programs into linear-bounded
    embedded machine code. <i>Science of Computer Programming</i>. Elsevier. <a href="https://doi.org/10.1016/j.scico.2010.06.004">https://doi.org/10.1016/j.scico.2010.06.004</a>
  chicago: Ghosal, Arkadeb, Daniel Iercan, Christoph Kirsch, Thomas A Henzinger, and
    Alberto Sangiovanni Vincentelli. “Separate Compilation of Hierarchical Real-Time
    Programs into Linear-Bounded Embedded Machine Code.” <i>Science of Computer Programming</i>.
    Elsevier, 2012. <a href="https://doi.org/10.1016/j.scico.2010.06.004">https://doi.org/10.1016/j.scico.2010.06.004</a>.
  ieee: A. Ghosal, D. Iercan, C. Kirsch, T. A. Henzinger, and A. Sangiovanni Vincentelli,
    “Separate compilation of hierarchical real-time programs into linear-bounded embedded
    machine code,” <i>Science of Computer Programming</i>, vol. 77, no. 2. Elsevier,
    pp. 96–112, 2012.
  ista: Ghosal A, Iercan D, Kirsch C, Henzinger TA, Sangiovanni Vincentelli A. 2012.
    Separate compilation of hierarchical real-time programs into linear-bounded embedded
    machine code. Science of Computer Programming. 77(2), 96–112.
  mla: Ghosal, Arkadeb, et al. “Separate Compilation of Hierarchical Real-Time Programs
    into Linear-Bounded Embedded Machine Code.” <i>Science of Computer Programming</i>,
    vol. 77, no. 2, Elsevier, 2012, pp. 96–112, doi:<a href="https://doi.org/10.1016/j.scico.2010.06.004">10.1016/j.scico.2010.06.004</a>.
  short: A. Ghosal, D. Iercan, C. Kirsch, T.A. Henzinger, A. Sangiovanni Vincentelli,
    Science of Computer Programming 77 (2012) 96–112.
date_created: 2018-12-11T12:05:26Z
date_published: 2012-02-01T00:00:00Z
date_updated: 2021-01-12T07:52:32Z
day: '01'
department:
- _id: ToHe
doi: 10.1016/j.scico.2010.06.004
intvolume: '        77'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: 96 - 112
publication: Science of Computer Programming
publication_status: published
publisher: Elsevier
publist_id: '2370'
quality_controlled: '1'
scopus_import: 1
status: public
title: Separate compilation of hierarchical real-time programs into linear-bounded
  embedded machine code
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 77
year: '2012'
...
---
_id: '3846'
abstract:
- lang: eng
  text: We summarize classical and recent results about two-player games played on
    graphs with ω-regular objectives. These games have applications in the verification
    and synthesis of reactive systems. Important distinctions are whether a graph
    game is turn-based or concurrent; deterministic or stochastic; zero-sum or not.
    We cluster known results and open problems according to these classifications.
acknowledgement: This research was supported in part by the ONR grant N00014-02-1-0671,
  by the AFOSR MURI grant F49620-00-1-0327, and by the NSF grants CCR-9988172, CCR-0085949,
  and CCR-0225610.
article_processing_charge: No
article_type: original
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
citation:
  ama: Chatterjee K, Henzinger TA. A survey of stochastic ω regular games. <i>Journal
    of Computer and System Sciences</i>. 2012;78(2):394-413. doi:<a href="https://doi.org/10.1016/j.jcss.2011.05.002">10.1016/j.jcss.2011.05.002</a>
  apa: Chatterjee, K., &#38; Henzinger, T. A. (2012). A survey of stochastic ω regular
    games. <i>Journal of Computer and System Sciences</i>. Elsevier. <a href="https://doi.org/10.1016/j.jcss.2011.05.002">https://doi.org/10.1016/j.jcss.2011.05.002</a>
  chicago: Chatterjee, Krishnendu, and Thomas A Henzinger. “A Survey of Stochastic
    ω Regular Games.” <i>Journal of Computer and System Sciences</i>. Elsevier, 2012.
    <a href="https://doi.org/10.1016/j.jcss.2011.05.002">https://doi.org/10.1016/j.jcss.2011.05.002</a>.
  ieee: K. Chatterjee and T. A. Henzinger, “A survey of stochastic ω regular games,”
    <i>Journal of Computer and System Sciences</i>, vol. 78, no. 2. Elsevier, pp.
    394–413, 2012.
  ista: Chatterjee K, Henzinger TA. 2012. A survey of stochastic ω regular games.
    Journal of Computer and System Sciences. 78(2), 394–413.
  mla: Chatterjee, Krishnendu, and Thomas A. Henzinger. “A Survey of Stochastic ω
    Regular Games.” <i>Journal of Computer and System Sciences</i>, vol. 78, no. 2,
    Elsevier, 2012, pp. 394–413, doi:<a href="https://doi.org/10.1016/j.jcss.2011.05.002">10.1016/j.jcss.2011.05.002</a>.
  short: K. Chatterjee, T.A. Henzinger, Journal of Computer and System Sciences 78
    (2012) 394–413.
date_created: 2018-12-11T12:05:29Z
date_published: 2012-03-02T00:00:00Z
date_updated: 2022-05-24T08:00:54Z
day: '02'
ddc:
- '000'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1016/j.jcss.2011.05.002
file:
- access_level: open_access
  checksum: 241b939deb4517cdd4426d49c67e3fa2
  content_type: application/pdf
  creator: kschuh
  date_created: 2019-01-29T10:54:28Z
  date_updated: 2020-07-14T12:46:17Z
  file_id: '5897'
  file_name: a_survey_of_stochastic_omega-regular_games.pdf
  file_size: 336450
  relation: main_file
file_date_updated: 2020-07-14T12:46:17Z
has_accepted_license: '1'
intvolume: '        78'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.jcss.2011.05.002
month: '03'
oa: 1
oa_version: Submitted Version
page: 394 - 413
publication: Journal of Computer and System Sciences
publication_status: published
publisher: Elsevier
publist_id: '2341'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A survey of stochastic ω regular games
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 78
year: '2012'
...
---
_id: '3163'
abstract:
- lang: eng
  text: We study multi-label prediction for structured output sets, a problem that
    occurs, for example, in object detection in images, secondary structure prediction
    in computational biology, and graph matching with symmetries. Conventional multilabel
    classification techniques are typically not applicable in this situation, because
    they require explicit enumeration of the label set, which is infeasible in case
    of structured outputs. Relying on techniques originally designed for single-label
    structured prediction, in particular structured support vector machines, results
    in reduced prediction accuracy, or leads to infeasible optimization problems.
    In this work we derive a maximum-margin training formulation for multi-label structured
    prediction that remains computationally tractable while achieving high prediction
    accuracy. It also shares most beneficial properties with single-label maximum-margin
    approaches, in particular formulation as a convex optimization problem, efficient
    working set training, and PAC-Bayesian generalization bounds.
author:
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
citation:
  ama: 'Lampert C. Maximum margin multi-label structured prediction. In: Neural Information
    Processing Systems; 2011.'
  apa: 'Lampert, C. (2011). Maximum margin multi-label structured prediction. Presented
    at the NIPS: Neural Information Processing Systems, Granada, Spain: Neural Information
    Processing Systems.'
  chicago: Lampert, Christoph. “Maximum Margin Multi-Label Structured Prediction.”
    Neural Information Processing Systems, 2011.
  ieee: 'C. Lampert, “Maximum margin multi-label structured prediction,” presented
    at the NIPS: Neural Information Processing Systems, Granada, Spain, 2011.'
  ista: 'Lampert C. 2011. Maximum margin multi-label structured prediction. NIPS:
    Neural Information Processing Systems.'
  mla: Lampert, Christoph. <i>Maximum Margin Multi-Label Structured Prediction</i>.
    Neural Information Processing Systems, 2011.
  short: C. Lampert, in:, Neural Information Processing Systems, 2011.
conference:
  end_date: 2011-12-14
  location: Granada, Spain
  name: 'NIPS: Neural Information Processing Systems'
  start_date: 2011-12-12
date_created: 2018-12-11T12:01:45Z
date_published: 2011-12-01T00:00:00Z
date_updated: 2023-10-17T11:47:35Z
day: '01'
department:
- _id: ChLa
language:
- iso: eng
month: '12'
oa_version: None
publication_status: published
publisher: Neural Information Processing Systems
publist_id: '3522'
quality_controlled: '1'
related_material:
  record:
  - id: '3322'
    relation: later_version
    status: public
scopus_import: 1
status: public
title: Maximum margin multi-label structured prediction
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3264'
abstract:
- lang: eng
  text: Verification of programs with procedures, multi-threaded programs, and higher-order
    functional programs can be effectively au- tomated using abstraction and refinement
    schemes that rely on spurious counterexamples for abstraction discovery. The analysis
    of counterexam- ples can be automated by a series of interpolation queries, or,
    alterna- tively, as a constraint solving query expressed by a set of recursion
    free Horn clauses. (A set of interpolation queries can be formulated as a single
    constraint over Horn clauses with linear dependency structure between the unknown
    relations.) In this paper we present an algorithm for solving recursion free Horn
    clauses over a combined theory of linear real/rational arithmetic and uninterpreted
    functions. Our algorithm performs resolu- tion to deal with the clausal structure
    and relies on partial solutions to deal with (non-local) instances of functionality
    axioms.
alternative_title:
- LNCS
author:
- first_name: Ashutosh
  full_name: Gupta, Ashutosh
  id: 335E5684-F248-11E8-B48F-1D18A9856A87
  last_name: Gupta
- first_name: Corneliu
  full_name: Popeea, Corneliu
  last_name: Popeea
- first_name: Andrey
  full_name: Rybalchenko, Andrey
  last_name: Rybalchenko
citation:
  ama: 'Gupta A, Popeea C, Rybalchenko A. Solving recursion-free Horn clauses over
    LI+UIF. In: Yang H, ed. Vol 7078. Springer; 2011:188-203. doi:<a href="https://doi.org/10.1007/978-3-642-25318-8_16">10.1007/978-3-642-25318-8_16</a>'
  apa: 'Gupta, A., Popeea, C., &#38; Rybalchenko, A. (2011). Solving recursion-free
    Horn clauses over LI+UIF. In H. Yang (Ed.) (Vol. 7078, pp. 188–203). Presented
    at the APLAS: Asian Symposium on Programming Languages and Systems, Kenting, Taiwan:
    Springer. <a href="https://doi.org/10.1007/978-3-642-25318-8_16">https://doi.org/10.1007/978-3-642-25318-8_16</a>'
  chicago: Gupta, Ashutosh, Corneliu Popeea, and Andrey Rybalchenko. “Solving Recursion-Free
    Horn Clauses over LI+UIF.” edited by Hongseok Yang, 7078:188–203. Springer, 2011.
    <a href="https://doi.org/10.1007/978-3-642-25318-8_16">https://doi.org/10.1007/978-3-642-25318-8_16</a>.
  ieee: 'A. Gupta, C. Popeea, and A. Rybalchenko, “Solving recursion-free Horn clauses
    over LI+UIF,” presented at the APLAS: Asian Symposium on Programming Languages
    and Systems, Kenting, Taiwan, 2011, vol. 7078, pp. 188–203.'
  ista: 'Gupta A, Popeea C, Rybalchenko A. 2011. Solving recursion-free Horn clauses
    over LI+UIF. APLAS: Asian Symposium on Programming Languages and Systems, LNCS,
    vol. 7078, 188–203.'
  mla: Gupta, Ashutosh, et al. <i>Solving Recursion-Free Horn Clauses over LI+UIF</i>.
    Edited by Hongseok Yang, vol. 7078, Springer, 2011, pp. 188–203, doi:<a href="https://doi.org/10.1007/978-3-642-25318-8_16">10.1007/978-3-642-25318-8_16</a>.
  short: A. Gupta, C. Popeea, A. Rybalchenko, in:, H. Yang (Ed.), Springer, 2011,
    pp. 188–203.
conference:
  end_date: 2011-12-07
  location: Kenting, Taiwan
  name: 'APLAS: Asian Symposium on Programming Languages and Systems'
  start_date: 2011-12-05
date_created: 2018-12-11T12:02:20Z
date_published: 2011-12-05T00:00:00Z
date_updated: 2021-01-12T07:42:15Z
day: '05'
department:
- _id: ToHe
doi: 10.1007/978-3-642-25318-8_16
ec_funded: 1
editor:
- first_name: Hongseok
  full_name: Yang, Hongseok
  last_name: Yang
intvolume: '      7078'
language:
- iso: eng
month: '12'
oa_version: None
page: 188 - 203
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '267989'
  name: Quantitative Reactive Modeling
publication_status: published
publisher: Springer
publist_id: '3383'
quality_controlled: '1'
status: public
title: Solving recursion-free Horn clauses over LI+UIF
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 7078
year: '2011'
...
---
_id: '3266'
abstract:
- lang: eng
  text: We present a joint image segmentation and labeling model (JSL) which, given
    a bag of figure-ground segment hypotheses extracted at multiple image locations
    and scales, constructs a joint probability distribution over both the compatible
    image interpretations (tilings or image segmentations) composed from those segments,
    and over their labeling into categories. The process of drawing samples from the
    joint distribution can be interpreted as first sampling tilings, modeled as maximal
    cliques, from a graph connecting spatially non-overlapping segments in the bag
    [1], followed by sampling labels for those segments, conditioned on the choice
    of a particular tiling. We learn the segmentation and labeling parameters jointly,
    based on Maximum Likelihood with a novel Incremental Saddle Point estimation procedure.
    The partition function over tilings and labelings is increasingly more accurately
    approximated by including incorrect configurations that a not-yet-competent model
    rates probable during learning. We show that the proposed methodologymatches the
    current state of the art in the Stanford dataset [2], as well as in VOC2010, where
    41.7% accuracy on the test set is achieved.
author:
- first_name: Adrian
  full_name: Ion, Adrian
  id: 29F89302-F248-11E8-B48F-1D18A9856A87
  last_name: Ion
- first_name: Joao
  full_name: Carreira, Joao
  last_name: Carreira
- first_name: Cristian
  full_name: Sminchisescu, Cristian
  last_name: Sminchisescu
citation:
  ama: 'Ion A, Carreira J, Sminchisescu C. Probabilistic joint image segmentation
    and labeling. In: <i>NIPS Proceedings</i>. Vol 24. Neural Information Processing
    Systems Foundation; 2011:1827-1835.'
  apa: 'Ion, A., Carreira, J., &#38; Sminchisescu, C. (2011). Probabilistic joint
    image segmentation and labeling. In <i>NIPS Proceedings</i> (Vol. 24, pp. 1827–1835).
    Granada, Spain: Neural Information Processing Systems Foundation.'
  chicago: Ion, Adrian, Joao Carreira, and Cristian Sminchisescu. “Probabilistic Joint
    Image Segmentation and Labeling.” In <i>NIPS Proceedings</i>, 24:1827–35. Neural
    Information Processing Systems Foundation, 2011.
  ieee: A. Ion, J. Carreira, and C. Sminchisescu, “Probabilistic joint image segmentation
    and labeling,” in <i>NIPS Proceedings</i>, Granada, Spain, 2011, vol. 24, pp.
    1827–1835.
  ista: 'Ion A, Carreira J, Sminchisescu C. 2011. Probabilistic joint image segmentation
    and labeling. NIPS Proceedings. NIPS: Neural Information Processing Systems vol.
    24, 1827–1835.'
  mla: Ion, Adrian, et al. “Probabilistic Joint Image Segmentation and Labeling.”
    <i>NIPS Proceedings</i>, vol. 24, Neural Information Processing Systems Foundation,
    2011, pp. 1827–35.
  short: A. Ion, J. Carreira, C. Sminchisescu, in:, NIPS Proceedings, Neural Information
    Processing Systems Foundation, 2011, pp. 1827–1835.
conference:
  end_date: 2011-12-14
  location: Granada, Spain
  name: 'NIPS: Neural Information Processing Systems'
  start_date: 2011-12-12
date_created: 2018-12-11T12:02:21Z
date_published: 2011-12-01T00:00:00Z
date_updated: 2021-01-12T07:42:15Z
day: '01'
department:
- _id: HeEd
intvolume: '        24'
language:
- iso: eng
month: '12'
oa_version: None
page: 1827 - 1835
publication: NIPS Proceedings
publication_status: published
publisher: Neural Information Processing Systems Foundation
publist_id: '3381'
quality_controlled: '1'
scopus_import: 1
status: public
title: Probabilistic joint image segmentation and labeling
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2011'
...
---
_id: '3267'
abstract:
- lang: eng
  text: 'We address the problem of localizing homology classes, namely, finding the
    cycle representing a given class with the most concise geometric measure. We study
    the problem with different measures: volume, diameter and radius. For volume,
    that is, the 1-norm of a cycle, two main results are presented. First, we prove
    that the problem is NP-hard to approximate within any constant factor. Second,
    we prove that for homology of dimension two or higher, the problem is NP-hard
    to approximate even when the Betti number is O(1). The latter result leads to
    the inapproximability of the problem of computing the nonbounding cycle with the
    smallest volume and computing cycles representing a homology basis with the minimal
    total volume. As for the other two measures defined by pairwise geodesic distance,
    diameter and radius, we show that the localization problem is NP-hard for diameter
    but is polynomial for radius. Our work is restricted to homology over the ℤ2 field.'
author:
- first_name: Chao
  full_name: Chen, Chao
  id: 3E92416E-F248-11E8-B48F-1D18A9856A87
  last_name: Chen
- first_name: Daniel
  full_name: Freedman, Daniel
  last_name: Freedman
citation:
  ama: Chen C, Freedman D. Hardness results for homology localization. <i>Discrete
    &#38; Computational Geometry</i>. 2011;45(3):425-448. doi:<a href="https://doi.org/10.1007/s00454-010-9322-8">10.1007/s00454-010-9322-8</a>
  apa: Chen, C., &#38; Freedman, D. (2011). Hardness results for homology localization.
    <i>Discrete &#38; Computational Geometry</i>. Springer. <a href="https://doi.org/10.1007/s00454-010-9322-8">https://doi.org/10.1007/s00454-010-9322-8</a>
  chicago: Chen, Chao, and Daniel Freedman. “Hardness Results for Homology Localization.”
    <i>Discrete &#38; Computational Geometry</i>. Springer, 2011. <a href="https://doi.org/10.1007/s00454-010-9322-8">https://doi.org/10.1007/s00454-010-9322-8</a>.
  ieee: C. Chen and D. Freedman, “Hardness results for homology localization,” <i>Discrete
    &#38; Computational Geometry</i>, vol. 45, no. 3. Springer, pp. 425–448, 2011.
  ista: Chen C, Freedman D. 2011. Hardness results for homology localization. Discrete
    &#38; Computational Geometry. 45(3), 425–448.
  mla: Chen, Chao, and Daniel Freedman. “Hardness Results for Homology Localization.”
    <i>Discrete &#38; Computational Geometry</i>, vol. 45, no. 3, Springer, 2011,
    pp. 425–48, doi:<a href="https://doi.org/10.1007/s00454-010-9322-8">10.1007/s00454-010-9322-8</a>.
  short: C. Chen, D. Freedman, Discrete &#38; Computational Geometry 45 (2011) 425–448.
date_created: 2018-12-11T12:02:21Z
date_published: 2011-01-14T00:00:00Z
date_updated: 2023-02-21T16:07:10Z
day: '14'
department:
- _id: HeEd
doi: 10.1007/s00454-010-9322-8
intvolume: '        45'
issue: '3'
language:
- iso: eng
month: '01'
oa_version: None
page: 425 - 448
publication: Discrete & Computational Geometry
publication_status: published
publisher: Springer
publist_id: '3379'
quality_controlled: '1'
related_material:
  record:
  - id: '10909'
    relation: earlier_version
    status: public
scopus_import: 1
status: public
title: Hardness results for homology localization
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 45
year: '2011'
...
---
_id: '3269'
abstract:
- lang: eng
  text: The unintentional scattering of light between neighboring surfaces in complex
    projection environments increases the brightness and decreases the contrast, disrupting
    the appearance of the desired imagery. To achieve satisfactory projection results,
    the inverse problem of global illumination must be solved to cancel this secondary
    scattering. In this paper, we propose a global illumination cancellation method
    that minimizes the perceptual difference between the desired imagery and the actual
    total illumination in the resulting physical environment. Using Gauss-Newton and
    active set methods, we design a fast solver for the bound constrained nonlinear
    least squares problem raised by the perceptual error metrics. Our solver is further
    accelerated with a CUDA implementation and multi-resolution method to achieve
    1–2 fps for problems with approximately 3000 variables. We demonstrate the global
    illumination cancellation algorithm with our multi-projector system. Results show
    that our method preserves the color fidelity of the desired imagery significantly
    better than previous methods.
article_processing_charge: No
article_type: original
author:
- first_name: Yu
  full_name: Sheng, Yu
  last_name: Sheng
- first_name: Barbara
  full_name: Cutler, Barbara
  last_name: Cutler
- first_name: Chao
  full_name: Chen, Chao
  id: 3E92416E-F248-11E8-B48F-1D18A9856A87
  last_name: Chen
- first_name: Joshua
  full_name: Nasman, Joshua
  last_name: Nasman
citation:
  ama: Sheng Y, Cutler B, Chen C, Nasman J. Perceptual global illumination cancellation
    in complex projection environments. <i>Computer Graphics Forum</i>. 2011;30(4):1261-1268.
    doi:<a href="https://doi.org/10.1111/j.1467-8659.2011.01985.x">10.1111/j.1467-8659.2011.01985.x</a>
  apa: Sheng, Y., Cutler, B., Chen, C., &#38; Nasman, J. (2011). Perceptual global
    illumination cancellation in complex projection environments. <i>Computer Graphics
    Forum</i>. Wiley-Blackwell. <a href="https://doi.org/10.1111/j.1467-8659.2011.01985.x">https://doi.org/10.1111/j.1467-8659.2011.01985.x</a>
  chicago: Sheng, Yu, Barbara Cutler, Chao Chen, and Joshua Nasman. “Perceptual Global
    Illumination Cancellation in Complex Projection Environments.” <i>Computer Graphics
    Forum</i>. Wiley-Blackwell, 2011. <a href="https://doi.org/10.1111/j.1467-8659.2011.01985.x">https://doi.org/10.1111/j.1467-8659.2011.01985.x</a>.
  ieee: Y. Sheng, B. Cutler, C. Chen, and J. Nasman, “Perceptual global illumination
    cancellation in complex projection environments,” <i>Computer Graphics Forum</i>,
    vol. 30, no. 4. Wiley-Blackwell, pp. 1261–1268, 2011.
  ista: Sheng Y, Cutler B, Chen C, Nasman J. 2011. Perceptual global illumination
    cancellation in complex projection environments. Computer Graphics Forum. 30(4),
    1261–1268.
  mla: Sheng, Yu, et al. “Perceptual Global Illumination Cancellation in Complex Projection
    Environments.” <i>Computer Graphics Forum</i>, vol. 30, no. 4, Wiley-Blackwell,
    2011, pp. 1261–68, doi:<a href="https://doi.org/10.1111/j.1467-8659.2011.01985.x">10.1111/j.1467-8659.2011.01985.x</a>.
  short: Y. Sheng, B. Cutler, C. Chen, J. Nasman, Computer Graphics Forum 30 (2011)
    1261–1268.
date_created: 2018-12-11T12:02:22Z
date_published: 2011-07-19T00:00:00Z
date_updated: 2021-01-12T07:42:16Z
day: '19'
department:
- _id: HeEd
doi: 10.1111/j.1467-8659.2011.01985.x
intvolume: '        30'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://www.cs.cmu.edu/%7Eshengyu/download/egsr2011_paper.pdf
month: '07'
oa: 1
oa_version: Published Version
page: 1261 - 1268
publication: Computer Graphics Forum
publication_status: published
publisher: Wiley-Blackwell
publist_id: '3377'
quality_controlled: '1'
scopus_import: 1
status: public
title: Perceptual global illumination cancellation in complex projection environments
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 30
year: '2011'
...
---
_id: '3270'
abstract:
- lang: eng
  text: 'The persistence diagram of a filtered simplicial com- plex is usually computed
    by reducing the boundary matrix of the complex. We introduce a simple op- timization
    technique: by processing the simplices of the complex in decreasing dimension,
    we can “kill” columns (i.e., set them to zero) without reducing them. This technique
    completely avoids reduction on roughly half of the columns. We demonstrate that
    this idea significantly improves the running time of the reduction algorithm in
    practice. We also give an output-sensitive complexity analysis for the new al-
    gorithm which yields to sub-cubic asymptotic bounds under certain assumptions.'
author:
- first_name: Chao
  full_name: Chen, Chao
  id: 3E92416E-F248-11E8-B48F-1D18A9856A87
  last_name: Chen
- first_name: Michael
  full_name: Kerber, Michael
  id: 36E4574A-F248-11E8-B48F-1D18A9856A87
  last_name: Kerber
  orcid: 0000-0002-8030-9299
citation:
  ama: 'Chen C, Kerber M. Persistent homology computation with a twist. In: TU Dortmund;
    2011:197-200.'
  apa: 'Chen, C., &#38; Kerber, M. (2011). Persistent homology computation with a
    twist (pp. 197–200). Presented at the EuroCG: European Workshop on Computational
    Geometry, Morschach, Switzerland: TU Dortmund.'
  chicago: Chen, Chao, and Michael Kerber. “Persistent Homology Computation with a
    Twist,” 197–200. TU Dortmund, 2011.
  ieee: 'C. Chen and M. Kerber, “Persistent homology computation with a twist,” presented
    at the EuroCG: European Workshop on Computational Geometry, Morschach, Switzerland,
    2011, pp. 197–200.'
  ista: 'Chen C, Kerber M. 2011. Persistent homology computation with a twist. EuroCG:
    European Workshop on Computational Geometry, 197–200.'
  mla: Chen, Chao, and Michael Kerber. <i>Persistent Homology Computation with a Twist</i>.
    TU Dortmund, 2011, pp. 197–200.
  short: C. Chen, M. Kerber, in:, TU Dortmund, 2011, pp. 197–200.
conference:
  end_date: 2011-03-30
  location: Morschach, Switzerland
  name: 'EuroCG: European Workshop on Computational Geometry'
  start_date: 2011-03-28
date_created: 2018-12-11T12:02:22Z
date_published: 2011-01-01T00:00:00Z
date_updated: 2021-01-12T07:42:17Z
day: '01'
department:
- _id: HeEd
language:
- iso: eng
month: '01'
oa_version: None
page: 197 - 200
publication_status: published
publisher: TU Dortmund
publist_id: '3376'
quality_controlled: '1'
status: public
title: Persistent homology computation with a twist
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3271'
abstract:
- lang: eng
  text: In this paper we present an efficient framework for computation of persis-
    tent homology of cubical data in arbitrary dimensions. An existing algorithm using
    simplicial complexes is adapted to the setting of cubical complexes. The proposed
    approach enables efficient application of persistent homology in domains where
    the data is naturally given in a cubical form. By avoiding triangulation of the
    data, we significantly reduce the size of the complex. We also present a data-structure
    de- signed to compactly store and quickly manipulate cubical complexes. By means
    of numerical experiments, we show high speed and memory efficiency of our ap-
    proach. We compare our framework to other available implementations, showing its
    superiority. Finally, we report performance on selected 3D and 4D data-sets.
alternative_title:
- Theory, Algorithms, and Applications
author:
- first_name: Hubert
  full_name: Wagner, Hubert
  last_name: Wagner
- first_name: Chao
  full_name: Chen, Chao
  id: 3E92416E-F248-11E8-B48F-1D18A9856A87
  last_name: Chen
- first_name: Erald
  full_name: Vuçini, Erald
  last_name: Vuçini
citation:
  ama: 'Wagner H, Chen C, Vuçini E. Efficient computation of persistent homology for
    cubical data. In: Peikert R, Hauser H, Carr H, Fuchs R, eds. <i>Topological Methods
    in Data Analysis and Visualization II</i>. Springer; 2011:91-106. doi:<a href="https://doi.org/10.1007/978-3-642-23175-9_7">10.1007/978-3-642-23175-9_7</a>'
  apa: Wagner, H., Chen, C., &#38; Vuçini, E. (2011). Efficient computation of persistent
    homology for cubical data. In R. Peikert, H. Hauser, H. Carr, &#38; R. Fuchs (Eds.),
    <i>Topological Methods in Data Analysis and Visualization II</i> (pp. 91–106).
    Springer. <a href="https://doi.org/10.1007/978-3-642-23175-9_7">https://doi.org/10.1007/978-3-642-23175-9_7</a>
  chicago: Wagner, Hubert, Chao Chen, and Erald Vuçini. “Efficient Computation of
    Persistent Homology for Cubical Data.” In <i>Topological Methods in Data Analysis
    and Visualization II</i>, edited by Ronald Peikert, Helwig Hauser, Hamish Carr,
    and Raphael Fuchs, 91–106. Springer, 2011. <a href="https://doi.org/10.1007/978-3-642-23175-9_7">https://doi.org/10.1007/978-3-642-23175-9_7</a>.
  ieee: H. Wagner, C. Chen, and E. Vuçini, “Efficient computation of persistent homology
    for cubical data,” in <i>Topological Methods in Data Analysis and Visualization
    II</i>, R. Peikert, H. Hauser, H. Carr, and R. Fuchs, Eds. Springer, 2011, pp.
    91–106.
  ista: 'Wagner H, Chen C, Vuçini E. 2011.Efficient computation of persistent homology
    for cubical data. In: Topological Methods in Data Analysis and Visualization II.
    Theory, Algorithms, and Applications, , 91–106.'
  mla: Wagner, Hubert, et al. “Efficient Computation of Persistent Homology for Cubical
    Data.” <i>Topological Methods in Data Analysis and Visualization II</i>, edited
    by Ronald Peikert et al., Springer, 2011, pp. 91–106, doi:<a href="https://doi.org/10.1007/978-3-642-23175-9_7">10.1007/978-3-642-23175-9_7</a>.
  short: H. Wagner, C. Chen, E. Vuçini, in:, R. Peikert, H. Hauser, H. Carr, R. Fuchs
    (Eds.), Topological Methods in Data Analysis and Visualization II, Springer, 2011,
    pp. 91–106.
date_created: 2018-12-11T12:02:23Z
date_published: 2011-11-14T00:00:00Z
date_updated: 2021-01-12T07:42:18Z
day: '14'
department:
- _id: HeEd
doi: 10.1007/978-3-642-23175-9_7
editor:
- first_name: Ronald
  full_name: Peikert, Ronald
  last_name: Peikert
- first_name: Helwig
  full_name: Hauser, Helwig
  last_name: Hauser
- first_name: Hamish
  full_name: Carr, Hamish
  last_name: Carr
- first_name: Raphael
  full_name: Fuchs, Raphael
  last_name: Fuchs
language:
- iso: eng
month: '11'
oa_version: None
page: 91 - 106
publication: Topological Methods in Data Analysis and Visualization II
publication_status: published
publisher: Springer
publist_id: '3375'
quality_controlled: '1'
scopus_import: 1
status: public
title: Efficient computation of persistent homology for cubical data
type: book_chapter
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3273'
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Jean-Léon
  full_name: Maître, Jean-Léon
  id: 48F1E0D8-F248-11E8-B48F-1D18A9856A87
  last_name: Maître
  orcid: 0000-0002-3688-1474
citation:
  ama: Maître J-L. Mechanics of adhesion and de‐adhesion in zebrafish germ layer progenitors.
    2011.
  apa: Maître, J.-L. (2011). <i>Mechanics of adhesion and de‐adhesion in zebrafish
    germ layer progenitors</i>. Institute of Science and Technology Austria.
  chicago: Maître, Jean-Léon. “Mechanics of Adhesion and De‐adhesion in Zebrafish
    Germ Layer Progenitors.” Institute of Science and Technology Austria, 2011.
  ieee: J.-L. Maître, “Mechanics of adhesion and de‐adhesion in zebrafish germ layer
    progenitors,” Institute of Science and Technology Austria, 2011.
  ista: Maître J-L. 2011. Mechanics of adhesion and de‐adhesion in zebrafish germ
    layer progenitors. Institute of Science and Technology Austria.
  mla: Maître, Jean-Léon. <i>Mechanics of Adhesion and De‐adhesion in Zebrafish Germ
    Layer Progenitors</i>. Institute of Science and Technology Austria, 2011.
  short: J.-L. Maître, Mechanics of Adhesion and De‐adhesion in Zebrafish Germ Layer
    Progenitors, Institute of Science and Technology Austria, 2011.
date_created: 2018-12-11T12:02:23Z
date_published: 2011-12-12T00:00:00Z
date_updated: 2023-09-07T11:30:16Z
day: '12'
degree_awarded: PhD
department:
- _id: CaHe
language:
- iso: eng
month: '12'
oa_version: None
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '3373'
status: public
supervisor:
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
title: Mechanics of adhesion and de‐adhesion in zebrafish germ layer progenitors
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2011'
...
---
_id: '3275'
abstract:
- lang: eng
  text: 'Chemokines organize immune cell trafficking by inducing either directed (tactic)
    or random (kinetic) migration and by activating integrins in order to support
    surface adhesion (haptic). Beyond that the same chemokines can establish clearly
    defined functional areas in secondary lymphoid organs. Until now it is unclear
    how chemokines can fulfill such diverse functions. One decisive prerequisite to
    explain these capacities is to know how chemokines are presented in tissue. In
    theory chemokines could occur either soluble or immobilized, and could be distributed
    either homogenously or as a concentration gradient. To dissect if and how the
    presenting mode of chemokines influences immune cells, I tested the response of
    dendritic cells (DCs) to differentially displayed chemokines. DCs are antigen
    presenting cells that reside in the periphery and migrate into draining lymph
    nodes (LNs) once exposed to inflammatory stimuli to activate naïve T cells. DCs
    are guided to and within the LN by the chemokine receptor CCR7, which has two
    ligands, the chemokines CCL19 and CCL21. Both CCR7 ligands are expressed by fibroblastic
    reticular cells in the LN, but differ in their ability to bind to heparan sulfate
    residues. CCL21 has a highly charged C-terminal extension, which mediates binding
    to anionic surfaces, whereas CCL19 is lacking such residues and likely distributes
    as a soluble molecule. This study shows that surface-bound CCL21 causes random,
    haptokinetic DC motility, which is confined to the chemokine coated area by insideout
    activation of β2 integrins that mediate cell binding to the surface. CCL19 on
    the other hand forms concentration gradients which trigger directional, chemotactic
    movement, but no surface adhesion. In addition DCs can actively manipulate this
    system by recruiting and activating serine proteases on their surfaces, which
    create - by proteolytically removing the adhesive C-terminus - a solubilized variant
    of CCL21 that functionally resembles CCL19. By generating a CCL21 concentration
    gradient DCs establish a positive feedback loop to recruit further DCs from the
    periphery to the CCL21 coated region. In addition DCs can sense chemotactic gradients
    as well as immobilized haptokinetic fields at the same time and integrate these
    signals. The result is chemotactically biased haptokinesis - directional migration
    confined to a chemokine coated track or area - which could explain the dynamic
    but spatially tightly controlled swarming leukocyte locomotion patterns that have
    been observed in lymphatic organs by intravital microscopists. The finding that
    DCs can approach soluble cues in a non-adhesive manner while they attach to surfaces
    coated with immobilized cues raises the question how these cells transmit intracellular
    forces to the environment, especially in the non-adherent migration mode. In order
    to migrate, cells have to generate and transmit force to the extracellular substrate.
    Force transmission is the prerequisite to procure an expansion of the leading
    edge and a forward motion of the whole cell body. In the current conceptions actin
    polymerization at the leading edge is coupled to extracellular ligands via the
    integrin family of transmembrane receptors, which allows the transmission of intracellular
    force. Against the paradigm of force transmission during migration, leukocytes,
    like DCs, are able to migrate in threedimensional environments without using integrin
    transmembrane receptors (Lämmermann et al., 2008). This reflects the biological
    function of leukocytes, as they can invade almost all tissues, whereby their migration
    has to be independent from the extracellular environment. How the cells can achieve
    this is unclear. For this study I examined DC migration in a defined threedimensional
    environment and highlighted actin-dynamics with the probe Lifeact-GFP. The result
    was that chemotactic DCs can switch between integrin-dependent and integrin- independent
    locomotion and can thereby adapt to the adhesive properties of their environment.
    If the cells are able to couple their actin cytoskeleton to the substrate, actin
    polymerization is entirely converted into protrusion. Without coupling the actin
    cortex undergoes slippage and retrograde actin flow can be observed. But retrograde
    actin flow can be completely compensated by higher actin polymerization rate keeping
    the migration velocity and the shape of the cells unaltered. Mesenchymal cells
    like fibroblast cannot balance the loss of adhesive interaction, cannot protrude
    into open space and, therefore, strictly depend on integrinmediated force coupling.
    This leukocyte specific phenomenon of “adaptive force transmission” endows these
    cells with the unique ability to transit and invade almost every type of tissue. '
acknowledgement: "I would like to express my sincere gratitude to the following people
  who made with their continuous support and encouragement this thesis possible: First,
  I want to thank Prof. Dr. Michael Sixt for his excellent supervision and mentoring,
  especially for the nice, relaxed working atmosphere, a lot of brilliant ideas and
  the freedom to work in my own way.\r\n\r\nProf. Dr. Reinhard Fässler for his constant
  support of the Sixt lab and for providing excellent working conditions. \r\n\r\nProf.
  Dr. Sanjiv Luther and Prof. Dr. Tobias Bollenbach for agreeing to be member of my
  thesis committee and to evaluate my work.\r\n\r\nDr. Walther Göhring, Carmen Schmitz,
  the Recombinant Protein Production core facility and the animal care takers for
  providing the “infrastructure” for this thesis. \r\n\r\nProf. Dr. Daniel Legler,
  Markus Bruckner and Dr. Julien Polleux for very fruitful collaborations and discussions.\r\n\r\nMy
  labmates for their help, a lot of discussions and to make the Sixt lab to a convenient
  place to work : Karin Hirsch, Tim Lämmeramnn, Holger Pflicke, Jörg Renkawitz, Michele
  Weber and Alexander Eichner All members of the Department of Molecular Medicine
  for their help. Especially I want to thank Sarah Schmidt, Karin Hirsch and Raphael
  Ruppert for their friendship, nice chats and their uncensored point of view. "
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Kathrin
  full_name: Schumann, Kathrin
  id: F44D762E-4F9D-11E9-B64C-9EB26CEFFB5F
  last_name: Schumann
citation:
  ama: Schumann K. The role of chemotactic gradients in dendritic cell migration.
    2011.
  apa: Schumann, K. (2011). <i>The role of chemotactic gradients in dendritic cell
    migration</i>. Institute of Science and Technology Austria.
  chicago: Schumann, Kathrin. “The Role of Chemotactic Gradients in Dendritic Cell
    Migration.” Institute of Science and Technology Austria, 2011.
  ieee: K. Schumann, “The role of chemotactic gradients in dendritic cell migration,”
    Institute of Science and Technology Austria, 2011.
  ista: Schumann K. 2011. The role of chemotactic gradients in dendritic cell migration.
    Institute of Science and Technology Austria.
  mla: Schumann, Kathrin. <i>The Role of Chemotactic Gradients in Dendritic Cell Migration</i>.
    Institute of Science and Technology Austria, 2011.
  short: K. Schumann, The Role of Chemotactic Gradients in Dendritic Cell Migration,
    Institute of Science and Technology Austria, 2011.
date_created: 2018-12-11T12:02:24Z
date_published: 2011-03-01T00:00:00Z
date_updated: 2023-09-07T11:31:48Z
day: '01'
ddc:
- '570'
- '579'
degree_awarded: PhD
department:
- _id: MiSi
file:
- access_level: closed
  checksum: e69eee6252660f0b694a2ea8923ddc72
  content_type: application/pdf
  creator: dernst
  date_created: 2019-03-26T08:12:21Z
  date_updated: 2020-07-14T12:46:06Z
  file_id: '6177'
  file_name: 2011_Thesis_Kathrin_Schumann.pdf
  file_size: 4487708
  relation: main_file
- access_level: open_access
  checksum: 71727d63f424b5b446f68f4b87ecadc0
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  date_created: 2021-02-22T11:24:30Z
  date_updated: 2021-02-22T11:24:30Z
  file_id: '9175'
  file_name: 2011_Thesis_Schumann_noS.pdf
  file_size: 4313127
  relation: main_file
  success: 1
file_date_updated: 2021-02-22T11:24:30Z
has_accepted_license: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: '141'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '3371'
pubrep_id: '11'
status: public
supervisor:
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
title: The role of chemotactic gradients in dendritic cell migration
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2011'
...
---
_id: '3287'
abstract:
- lang: eng
  text: 'Diffusing membrane constituents are constantly exposed to a variety of forces
    that influence their stochastic path. Single molecule experiments allow for resolving
    trajectories at extremely high spatial and temporal accuracy, thereby offering
    insights into en route interactions of the tracer. In this review we discuss approaches
    to derive information about the underlying processes, based on single molecule
    tracking experiments. In particular, we focus on a new versatile way to analyze
    single molecule diffusion in the absence of a full analytical treatment. The method
    is based on comprehensive comparison of an experimental data set against the hypothetical
    outcome of multiple experiments performed on the computer. Since Monte Carlo simulations
    can be easily and rapidly performed even on state-of-the-art PCs, our method provides
    a simple way for testing various - even complicated - diffusion models. We describe
    the new method in detail, and show the applicability on two specific examples:
    firstly, kinetic rate constants can be derived for the transient interaction of
    mobile membrane proteins; secondly, residence time and corral size can be extracted
    for confined diffusion.'
author:
- first_name: Verena
  full_name: Ruprecht, Verena
  id: 4D71A03A-F248-11E8-B48F-1D18A9856A87
  last_name: Ruprecht
  orcid: 0000-0003-4088-8633
- first_name: Markus
  full_name: Axmann, Markus
  last_name: Axmann
- first_name: Stefan
  full_name: Wieser, Stefan
  id: 355AA5A0-F248-11E8-B48F-1D18A9856A87
  last_name: Wieser
  orcid: 0000-0002-2670-2217
- first_name: Gerhard
  full_name: Schuetz, Gerhard
  last_name: Schuetz
citation:
  ama: Ruprecht V, Axmann M, Wieser S, Schuetz G. What can we learn from single molecule
    trajectories? <i>Current Protein &#38; Peptide Science</i>. 2011;12(8):714-724.
    doi:<a href="https://doi.org/10.2174/138920311798841753">10.2174/138920311798841753</a>
  apa: Ruprecht, V., Axmann, M., Wieser, S., &#38; Schuetz, G. (2011). What can we
    learn from single molecule trajectories? <i>Current Protein &#38; Peptide Science</i>.
    Bentham Science Publishers. <a href="https://doi.org/10.2174/138920311798841753">https://doi.org/10.2174/138920311798841753</a>
  chicago: Ruprecht, Verena, Markus Axmann, Stefan Wieser, and Gerhard Schuetz. “What
    Can We Learn from Single Molecule Trajectories?” <i>Current Protein &#38; Peptide
    Science</i>. Bentham Science Publishers, 2011. <a href="https://doi.org/10.2174/138920311798841753">https://doi.org/10.2174/138920311798841753</a>.
  ieee: V. Ruprecht, M. Axmann, S. Wieser, and G. Schuetz, “What can we learn from
    single molecule trajectories?,” <i>Current Protein &#38; Peptide Science</i>,
    vol. 12, no. 8. Bentham Science Publishers, pp. 714–724, 2011.
  ista: Ruprecht V, Axmann M, Wieser S, Schuetz G. 2011. What can we learn from single
    molecule trajectories? Current Protein &#38; Peptide Science. 12(8), 714–724.
  mla: Ruprecht, Verena, et al. “What Can We Learn from Single Molecule Trajectories?”
    <i>Current Protein &#38; Peptide Science</i>, vol. 12, no. 8, Bentham Science
    Publishers, 2011, pp. 714–24, doi:<a href="https://doi.org/10.2174/138920311798841753">10.2174/138920311798841753</a>.
  short: V. Ruprecht, M. Axmann, S. Wieser, G. Schuetz, Current Protein &#38; Peptide
    Science 12 (2011) 714–724.
date_created: 2018-12-11T12:02:28Z
date_published: 2011-12-01T00:00:00Z
date_updated: 2021-01-12T07:42:24Z
day: '01'
department:
- _id: CaHe
- _id: MiSi
doi: 10.2174/138920311798841753
intvolume: '        12'
issue: '8'
language:
- iso: eng
month: '12'
oa_version: None
page: 714 - 724
publication: Current Protein & Peptide Science
publication_status: published
publisher: Bentham Science Publishers
publist_id: '3358'
quality_controlled: '1'
scopus_import: 1
status: public
title: What can we learn from single molecule trajectories?
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2011'
...
---
_id: '3288'
abstract:
- lang: eng
  text: 'The zonula adherens (ZA) of epithelial cells is a site of cell-cell adhesion
    where cellular forces are exerted and resisted. Increasing evidence indicates
    that E-cadherin adhesion molecules at the ZA serve to sense force applied on the
    junctions and coordinate cytoskeletal responses to those forces. Efforts to understand
    the role that cadherins play in mechanotransduction have been limited by the lack
    of assays to measure the impact of forces on the ZA. In this study we used 4D
    imaging of GFP-tagged E-cadherin to analyse the movement of the ZA. Junctions
    in confluent epithelial monolayers displayed prominent movements oriented orthogonal
    (perpendicular) to the ZA itself. Two components were identified in these movements:
    a relatively slow unidirectional (translational) component that could be readily
    fitted by least-squares regression analysis, upon which were superimposed more
    rapid oscillatory movements. Myosin IIB was a dominant factor responsible for
    driving the unilateral translational movements. In contrast, frequency spectrum
    analysis revealed that depletion of Myosin IIA increased the power of the oscillatory
    movements. This implies that Myosin IIA may serve to dampen oscillatory movements
    of the ZA. This extends our recent analysis of Myosin II at the ZA to demonstrate
    that Myosin IIA and Myosin IIB make distinct contributions to junctional movement
    at the ZA.'
acknowledgement: his work was funded by the National Health and Medical Research Council
  (NHMRC) of Australia. M.S. was an Erwin Schroedinger postdoctoral fellow of the
  Austrian Science Fund (FWF), S.K.W. is supported by a UQ International Research
  Tuition Award and Research Scholarship, S.M .by an ANZ Trustees PhD Scholarship.
  A.S.Y. is a Research Fellow of the NHMRC. Confocal imaging was performed at the
  Australian Cancer Research Foundation (ACRF) Cancer Biology Imaging Centre at the
  Institute for Molecular Bioscience, established with the generous support of the
  ACRF.
author:
- first_name: Michael
  full_name: Smutny, Michael
  id: 3FE6E4E8-F248-11E8-B48F-1D18A9856A87
  last_name: Smutny
  orcid: 0000-0002-5920-9090
- first_name: Selwin
  full_name: Wu, Selwin
  last_name: Wu
- first_name: Guillermo
  full_name: Gomez, Guillermo
  last_name: Gomez
- first_name: Sabine
  full_name: Mangold, Sabine
  last_name: Mangold
- first_name: Alpha
  full_name: Yap, Alpha
  last_name: Yap
- first_name: Nicholas
  full_name: Hamilton, Nicholas
  last_name: Hamilton
citation:
  ama: Smutny M, Wu S, Gomez G, Mangold S, Yap A, Hamilton N. Multicomponent analysis
    of junctional movements regulated by Myosin II isoforms at the epithelial zonula
    adherens. <i>PLoS One</i>. 2011;6(7). doi:<a href="https://doi.org/10.1371/journal.pone.0022458">10.1371/journal.pone.0022458</a>
  apa: Smutny, M., Wu, S., Gomez, G., Mangold, S., Yap, A., &#38; Hamilton, N. (2011).
    Multicomponent analysis of junctional movements regulated by Myosin II isoforms
    at the epithelial zonula adherens. <i>PLoS One</i>. Public Library of Science.
    <a href="https://doi.org/10.1371/journal.pone.0022458">https://doi.org/10.1371/journal.pone.0022458</a>
  chicago: Smutny, Michael, Selwin Wu, Guillermo Gomez, Sabine Mangold, Alpha Yap,
    and Nicholas Hamilton. “Multicomponent Analysis of Junctional Movements Regulated
    by Myosin II Isoforms at the Epithelial Zonula Adherens.” <i>PLoS One</i>. Public
    Library of Science, 2011. <a href="https://doi.org/10.1371/journal.pone.0022458">https://doi.org/10.1371/journal.pone.0022458</a>.
  ieee: M. Smutny, S. Wu, G. Gomez, S. Mangold, A. Yap, and N. Hamilton, “Multicomponent
    analysis of junctional movements regulated by Myosin II isoforms at the epithelial
    zonula adherens,” <i>PLoS One</i>, vol. 6, no. 7. Public Library of Science, 2011.
  ista: Smutny M, Wu S, Gomez G, Mangold S, Yap A, Hamilton N. 2011. Multicomponent
    analysis of junctional movements regulated by Myosin II isoforms at the epithelial
    zonula adherens. PLoS One. 6(7).
  mla: Smutny, Michael, et al. “Multicomponent Analysis of Junctional Movements Regulated
    by Myosin II Isoforms at the Epithelial Zonula Adherens.” <i>PLoS One</i>, vol.
    6, no. 7, Public Library of Science, 2011, doi:<a href="https://doi.org/10.1371/journal.pone.0022458">10.1371/journal.pone.0022458</a>.
  short: M. Smutny, S. Wu, G. Gomez, S. Mangold, A. Yap, N. Hamilton, PLoS One 6 (2011).
date_created: 2018-12-11T12:02:28Z
date_published: 2011-07-22T00:00:00Z
date_updated: 2021-01-12T07:42:25Z
day: '22'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1371/journal.pone.0022458
file:
- access_level: open_access
  checksum: 57a5eb11dd05241c48c44f492b3ec3ac
  content_type: application/pdf
  creator: dernst
  date_created: 2019-05-10T10:51:43Z
  date_updated: 2020-07-14T12:46:06Z
  file_id: '6399'
  file_name: 2011_PLOS_Smutny.PDF
  file_size: 1984567
  relation: main_file
file_date_updated: 2020-07-14T12:46:06Z
has_accepted_license: '1'
intvolume: '         6'
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '3357'
quality_controlled: '1'
status: public
title: Multicomponent analysis of junctional movements regulated by Myosin II isoforms
  at the epithelial zonula adherens
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2011'
...
---
_id: '3290'
abstract:
- lang: eng
  text: 'Analysis of genomic data requires an efficient way to calculate likelihoods
    across very large numbers of loci. We describe a general method for finding the
    distribution of genealogies: we allow migration between demes, splitting of demes
    [as in the isolation-with-migration (IM) model], and recombination between linked
    loci. These processes are described by a set of linear recursions for the generating
    function of branch lengths. Under the infinite-sites model, the probability of
    any configuration of mutations can be found by differentiating this generating
    function. Such calculations are feasible for small numbers of sampled genomes:
    as an example, we show how the generating function can be derived explicitly for
    three genes under the two-deme IM model. This derivation is done automatically,
    using Mathematica. Given data from a large number of unlinked and nonrecombining
    blocks of sequence, these results can be used to find maximum-likelihood estimates
    of model parameters by tabulating the probabilities of all relevant mutational
    configurations and then multiplying across loci. The feasibility of the method
    is demonstrated by applying it to simulated data and to a data set previously
    analyzed by Wang and Hey (2010) consisting of 26,141 loci sampled from Drosophila
    simulans and D. melanogaster. Our results suggest that such likelihood calculations
    are scalable to genomic data as long as the numbers of sampled individuals and
    mutations per sequence block are small.'
author:
- first_name: Konrad
  full_name: Lohse, Konrad
  last_name: Lohse
- first_name: Richard
  full_name: Harrison, Richard
  last_name: Harrison
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: Lohse K, Harrison R, Barton NH. A general method for calculating likelihoods
    under the coalescent process. <i>Genetics</i>. 2011;189(3):977-987. doi:<a href="https://doi.org/10.1534/genetics.111.129569">10.1534/genetics.111.129569</a>
  apa: Lohse, K., Harrison, R., &#38; Barton, N. H. (2011). A general method for calculating
    likelihoods under the coalescent process. <i>Genetics</i>. Genetics Society of
    America. <a href="https://doi.org/10.1534/genetics.111.129569">https://doi.org/10.1534/genetics.111.129569</a>
  chicago: Lohse, Konrad, Richard Harrison, and Nicholas H Barton. “A General Method
    for Calculating Likelihoods under the Coalescent Process.” <i>Genetics</i>. Genetics
    Society of America, 2011. <a href="https://doi.org/10.1534/genetics.111.129569">https://doi.org/10.1534/genetics.111.129569</a>.
  ieee: K. Lohse, R. Harrison, and N. H. Barton, “A general method for calculating
    likelihoods under the coalescent process,” <i>Genetics</i>, vol. 189, no. 3. Genetics
    Society of America, pp. 977–987, 2011.
  ista: Lohse K, Harrison R, Barton NH. 2011. A general method for calculating likelihoods
    under the coalescent process. Genetics. 189(3), 977–987.
  mla: Lohse, Konrad, et al. “A General Method for Calculating Likelihoods under the
    Coalescent Process.” <i>Genetics</i>, vol. 189, no. 3, Genetics Society of America,
    2011, pp. 977–87, doi:<a href="https://doi.org/10.1534/genetics.111.129569">10.1534/genetics.111.129569</a>.
  short: K. Lohse, R. Harrison, N.H. Barton, Genetics 189 (2011) 977–987.
date_created: 2018-12-11T12:02:29Z
date_published: 2011-11-01T00:00:00Z
date_updated: 2021-01-12T07:42:26Z
day: '01'
department:
- _id: NiBa
doi: 10.1534/genetics.111.129569
ec_funded: 1
intvolume: '       189'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213358/
month: '11'
oa: 1
oa_version: Submitted Version
page: 977 - 987
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '250152'
  name: Limits to selection in biology and in evolutionary computation
publication: Genetics
publication_status: published
publisher: Genetics Society of America
publist_id: '3355'
quality_controlled: '1'
scopus_import: 1
status: public
title: A general method for calculating likelihoods under the coalescent process
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 189
year: '2011'
...
---
_id: '3297'
abstract:
- lang: eng
  text: "Animating detailed liquid surfaces has always been a challenge for computer
    graphics researchers and visual effects artists. Over the past few years, researchers
    in this field have focused on mesh-based surface tracking to synthesize extremely
    detailed liquid surfaces as efficiently as possible. This course provides a solid
    understanding of the steps required to create a fluid simulator with a mesh-based
    liquid surface.\r\n\r\nThe course begins with an overview of several existing
    liquid-surface-tracking techniques and the pros and cons of each method. Then
    it explains how to embed a triangle mesh into a finite-difference-based fluid
    simulator and describes several methods for allowing the liquid surface to merge
    together or break apart. The final section showcases the benefits and further
    applications of a mesh-based liquid surface, highlighting state-of-the-art methods
    for tracking colors and textures, maintaining liquid volume, preserving small
    surface features, and simulating realistic surface-tension waves."
article_number: '8'
author:
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
- first_name: Matthias
  full_name: Müller Fischer, Matthias
  last_name: Müller Fischer
- first_name: Tyson
  full_name: Brochu, Tyson
  last_name: Brochu
citation:
  ama: 'Wojtan C, Müller Fischer M, Brochu T. Liquid simulation with mesh-based surface
    tracking. In: ACM; 2011. doi:<a href="https://doi.org/10.1145/2037636.2037644">10.1145/2037636.2037644</a>'
  apa: 'Wojtan, C., Müller Fischer, M., &#38; Brochu, T. (2011). Liquid simulation
    with mesh-based surface tracking. Presented at the SIGGRAPH: Special Interest
    Group on Computer Graphics and Interactive Techniques, Vancouver, BC, Canada:
    ACM. <a href="https://doi.org/10.1145/2037636.2037644">https://doi.org/10.1145/2037636.2037644</a>'
  chicago: Wojtan, Chris, Matthias Müller Fischer, and Tyson Brochu. “Liquid Simulation
    with Mesh-Based Surface Tracking.” ACM, 2011. <a href="https://doi.org/10.1145/2037636.2037644">https://doi.org/10.1145/2037636.2037644</a>.
  ieee: 'C. Wojtan, M. Müller Fischer, and T. Brochu, “Liquid simulation with mesh-based
    surface tracking,” presented at the SIGGRAPH: Special Interest Group on Computer
    Graphics and Interactive Techniques, Vancouver, BC, Canada, 2011.'
  ista: 'Wojtan C, Müller Fischer M, Brochu T. 2011. Liquid simulation with mesh-based
    surface tracking. SIGGRAPH: Special Interest Group on Computer Graphics and Interactive
    Techniques, 8.'
  mla: Wojtan, Chris, et al. <i>Liquid Simulation with Mesh-Based Surface Tracking</i>.
    8, ACM, 2011, doi:<a href="https://doi.org/10.1145/2037636.2037644">10.1145/2037636.2037644</a>.
  short: C. Wojtan, M. Müller Fischer, T. Brochu, in:, ACM, 2011.
conference:
  end_date: 2011-08-11
  location: Vancouver, BC, Canada
  name: 'SIGGRAPH: Special Interest Group on Computer Graphics and Interactive Techniques'
  start_date: 2011-08-07
date_created: 2018-12-11T12:02:31Z
date_published: 2011-08-07T00:00:00Z
date_updated: 2023-02-23T11:21:02Z
day: '07'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1145/2037636.2037644
file:
- access_level: open_access
  checksum: 8d508ad7c82f50978acbaa4170ee0a75
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:13:34Z
  date_updated: 2020-07-14T12:46:06Z
  file_id: '5018'
  file_name: IST-2016-599-v1+1_meshyFluidsCourseSIGGRAPH2011.pdf
  file_size: 34672096
  relation: main_file
file_date_updated: 2020-07-14T12:46:06Z
has_accepted_license: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
publication_status: published
publisher: ACM
publist_id: '3344'
pubrep_id: '599'
quality_controlled: '1'
scopus_import: 1
status: public
title: Liquid simulation with mesh-based surface tracking
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
---
_id: '3298'
abstract:
- lang: eng
  text: We present a new algorithm for enforcing incompressibility for Smoothed Particle
    Hydrodynamics (SPH) by preserving uniform density across the domain. We propose
    a hybrid method that uses a Poisson solve on a coarse grid to enforce a divergence
    free velocity ﬁeld, followed by a local density correction of the particles. This
    avoids typical grid artifacts and maintains the Lagrangian nature of SPH by directly
    transferring pressures onto particles. Our method can be easily integrated with
    existing SPH techniques such as the incompressible PCISPH method as well as weakly
    compressible SPH by adding an additional force term. We show that this hybrid
    method accelerates convergence towards uniform density and permits a signiﬁcantly
    larger time step compared to earlier approaches while producing similar results.
    We demonstrate our approach in a variety of scenarios with signiﬁcant pressure
    gradients such as splashing liquids.
author:
- first_name: Karthik
  full_name: Raveendran, Karthik
  last_name: Raveendran
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
- first_name: Greg
  full_name: Turk, Greg
  last_name: Turk
citation:
  ama: 'Raveendran K, Wojtan C, Turk G. Hybrid smoothed particle hydrodynamics. In:
    Spencer S, ed. ACM; 2011:33-42. doi:<a href="https://doi.org/10.1145/2019406.2019411">10.1145/2019406.2019411</a>'
  apa: 'Raveendran, K., Wojtan, C., &#38; Turk, G. (2011). Hybrid smoothed particle
    hydrodynamics. In S. Spencer (Ed.) (pp. 33–42). Presented at the SCA: ACM SIGGRAPH/Eurographics
    Symposium on Computer animation, Vancouver, Canada: ACM. <a href="https://doi.org/10.1145/2019406.2019411">https://doi.org/10.1145/2019406.2019411</a>'
  chicago: Raveendran, Karthik, Chris Wojtan, and Greg Turk. “Hybrid Smoothed Particle
    Hydrodynamics.” edited by Stephen Spencer, 33–42. ACM, 2011. <a href="https://doi.org/10.1145/2019406.2019411">https://doi.org/10.1145/2019406.2019411</a>.
  ieee: 'K. Raveendran, C. Wojtan, and G. Turk, “Hybrid smoothed particle hydrodynamics,”
    presented at the SCA: ACM SIGGRAPH/Eurographics Symposium on Computer animation,
    Vancouver, Canada, 2011, pp. 33–42.'
  ista: 'Raveendran K, Wojtan C, Turk G. 2011. Hybrid smoothed particle hydrodynamics.
    SCA: ACM SIGGRAPH/Eurographics Symposium on Computer animation, 33–42.'
  mla: Raveendran, Karthik, et al. <i>Hybrid Smoothed Particle Hydrodynamics</i>.
    Edited by Stephen Spencer, ACM, 2011, pp. 33–42, doi:<a href="https://doi.org/10.1145/2019406.2019411">10.1145/2019406.2019411</a>.
  short: K. Raveendran, C. Wojtan, G. Turk, in:, S. Spencer (Ed.), ACM, 2011, pp.
    33–42.
conference:
  end_date: 2011-08-07
  location: Vancouver, Canada
  name: 'SCA: ACM SIGGRAPH/Eurographics Symposium on Computer animation'
  start_date: 2011-08-05
date_created: 2018-12-11T12:02:32Z
date_published: 2011-08-05T00:00:00Z
date_updated: 2023-02-23T11:21:05Z
day: '05'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1145/2019406.2019411
editor:
- first_name: Stephen
  full_name: Spencer, Stephen
  last_name: Spencer
file:
- access_level: open_access
  checksum: 6579d27709946e0eefbfa60a456b4913
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:09:44Z
  date_updated: 2020-07-14T12:46:06Z
  file_id: '4769'
  file_name: IST-2016-598-v1+1_HybridSPH_Preprint.pdf
  file_size: 2536216
  relation: main_file
file_date_updated: 2020-07-14T12:46:06Z
has_accepted_license: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Submitted Version
page: 33 - 42
publication_status: published
publisher: ACM
publist_id: '3343'
pubrep_id: '598'
quality_controlled: '1'
scopus_import: 1
status: public
title: Hybrid smoothed particle hydrodynamics
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
year: '2011'
...
