---
_id: '2052'
abstract:
- lang: eng
text: A standard technique for solving the parameterized model checking problem
is to reduce it to the classic model checking problem of finitely many finite-state
systems. This work considers some of the theoretical power and limitations of
this technique. We focus on concurrent systems in which processes communicate
via pairwise rendezvous, as well as the special cases of disjunctive guards and
token passing; specifications are expressed in indexed temporal logic without
the next operator; and the underlying network topologies are generated by suitable
Monadic Second Order Logic formulas and graph operations. First, we settle the
exact computational complexity of the parameterized model checking problem for
some of our concurrent systems, and establish new decidability results for others.
Second, we consider the cases that model checking the parameterized system can
be reduced to model checking some fixed number of processes, the number is known
as a cutoff. We provide many cases for when such cutoffs can be computed, establish
lower bounds on the size of such cutoffs, and identify cases where no cutoff exists.
Third, we consider cases for which the parameterized system is equivalent to a
single finite-state system (more precisely a Büchi word automaton), and establish
tight bounds on the sizes of such automata.
acknowledgement: The second, third, fourth and fifth authors were supported by the
Austrian National Research Network S11403-N23 (RiSE) of the Austrian Science Fund
(FWF) and by the Vienna Science and Technology Fund (WWTF) through grants PROSEED,
ICT12-059, and VRG11-005.
alternative_title:
- LNCS
author:
- first_name: Benjamin
full_name: Aminof, Benjamin
id: 4A55BD00-F248-11E8-B48F-1D18A9856A87
last_name: Aminof
- first_name: Tomer
full_name: Kotek, Tomer
last_name: Kotek
- first_name: Sacha
full_name: Rubin, Sacha
last_name: Rubin
- first_name: Francesco
full_name: Spegni, Francesco
last_name: Spegni
- first_name: Helmut
full_name: Veith, Helmut
last_name: Veith
citation:
ama: 'Aminof B, Kotek T, Rubin S, Spegni F, Veith H. Parameterized model checking
of rendezvous systems. In: Baldan P, Gorla D, eds. Lecture Notes in Computer
Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture
Notes in Bioinformatics). Vol 8704. Schloss Dagstuhl - Leibniz-Zentrum für
Informatik; 2014:109-124. doi:10.1007/978-3-662-44584-6_9'
apa: 'Aminof, B., Kotek, T., Rubin, S., Spegni, F., & Veith, H. (2014). Parameterized
model checking of rendezvous systems. In P. Baldan & D. Gorla (Eds.), Lecture
Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics) (Vol. 8704, pp. 109–124). Rome, Italy:
Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.1007/978-3-662-44584-6_9'
chicago: Aminof, Benjamin, Tomer Kotek, Sacha Rubin, Francesco Spegni, and Helmut
Veith. “Parameterized Model Checking of Rendezvous Systems.” In Lecture Notes
in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics), edited by Paolo Baldan and Daniele Gorla,
8704:109–24. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2014. https://doi.org/10.1007/978-3-662-44584-6_9.
ieee: B. Aminof, T. Kotek, S. Rubin, F. Spegni, and H. Veith, “Parameterized model
checking of rendezvous systems,” in Lecture Notes in Computer Science (including
subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics),
Rome, Italy, 2014, vol. 8704, pp. 109–124.
ista: 'Aminof B, Kotek T, Rubin S, Spegni F, Veith H. 2014. Parameterized model
checking of rendezvous systems. Lecture Notes in Computer Science (including subseries
Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).
CONCUR: Concurrency Theory, LNCS, vol. 8704, 109–124.'
mla: Aminof, Benjamin, et al. “Parameterized Model Checking of Rendezvous Systems.”
Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial
Intelligence and Lecture Notes in Bioinformatics), edited by Paolo Baldan
and Daniele Gorla, vol. 8704, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2014, pp. 109–24, doi:10.1007/978-3-662-44584-6_9.
short: B. Aminof, T. Kotek, S. Rubin, F. Spegni, H. Veith, in:, P. Baldan, D. Gorla
(Eds.), Lecture Notes in Computer Science (Including Subseries Lecture Notes in
Artificial Intelligence and Lecture Notes in Bioinformatics), Schloss Dagstuhl
- Leibniz-Zentrum für Informatik, 2014, pp. 109–124.
conference:
end_date: 2014-09-05
location: Rome, Italy
name: 'CONCUR: Concurrency Theory'
start_date: 2014-09-02
date_created: 2018-12-11T11:55:26Z
date_published: 2014-09-01T00:00:00Z
date_updated: 2021-01-12T06:54:59Z
day: '01'
department:
- _id: KrCh
doi: 10.1007/978-3-662-44584-6_9
editor:
- first_name: Paolo
full_name: Baldan, Paolo
last_name: Baldan
- first_name: Daniele
full_name: Gorla, Daniele
last_name: Gorla
intvolume: ' 8704'
language:
- iso: eng
month: '09'
oa_version: None
page: 109 - 124
publication: Lecture Notes in Computer Science (including subseries Lecture Notes
in Artificial Intelligence and Lecture Notes in Bioinformatics)
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '4994'
quality_controlled: '1'
status: public
title: Parameterized model checking of rendezvous systems
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 8704
year: '2014'
...
---
_id: '2053'
abstract:
- lang: eng
text: In contrast to the usual understanding of probabilistic systems as stochastic
processes, recently these systems have also been regarded as transformers of probabilities.
In this paper, we give a natural definition of strong bisimulation for probabilistic
systems corresponding to this view that treats probability distributions as first-class
citizens. Our definition applies in the same way to discrete systems as well as
to systems with uncountable state and action spaces. Several examples demonstrate
that our definition refines the understanding of behavioural equivalences of probabilistic
systems. In particular, it solves a longstanding open problem concerning the representation
of memoryless continuous time by memoryfull continuous time. Finally, we give
algorithms for computing this bisimulation not only for finite but also for classes
of uncountably infinite systems.
acknowledgement: This work is supported by the EU 7th Framework Programme under grant
agreements 295261 (MEALS) and 318490 (SENSATION), Czech Science Foundation under
grant agreement P202/12/G061, the DFG Transregional Collaborative Research Centre
SFB/TR 14 AVACS, and by the CAS/SAFEA International Partnership Program for Creative
Research Teams.
alternative_title:
- LNCS
author:
- first_name: Holger
full_name: Hermanns, Holger
last_name: Hermanns
- first_name: Jan
full_name: Krčál, Jan
last_name: Krčál
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
citation:
ama: 'Hermanns H, Krčál J, Kretinsky J. Probabilistic bisimulation: Naturally on
distributions. In: Baldan P, Gorla D, eds. Lecture Notes in Computer Science
(Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes
in Bioinformatics). Vol 8704. Schloss Dagstuhl - Leibniz-Zentrum für Informatik;
2014:249-265. doi:10.1007/978-3-662-44584-6_18'
apa: 'Hermanns, H., Krčál, J., & Kretinsky, J. (2014). Probabilistic bisimulation:
Naturally on distributions. In P. Baldan & D. Gorla (Eds.), Lecture Notes
in Computer Science (including subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics) (Vol. 8704, pp. 249–265). Rome, Italy:
Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.1007/978-3-662-44584-6_18'
chicago: 'Hermanns, Holger, Jan Krčál, and Jan Kretinsky. “Probabilistic Bisimulation:
Naturally on Distributions.” In Lecture Notes in Computer Science (Including
Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics),
edited by Paolo Baldan and Daniele Gorla, 8704:249–65. Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2014. https://doi.org/10.1007/978-3-662-44584-6_18.'
ieee: 'H. Hermanns, J. Krčál, and J. Kretinsky, “Probabilistic bisimulation: Naturally
on distributions,” in Lecture Notes in Computer Science (including subseries
Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics),
Rome, Italy, 2014, vol. 8704, pp. 249–265.'
ista: 'Hermanns H, Krčál J, Kretinsky J. 2014. Probabilistic bisimulation: Naturally
on distributions. Lecture Notes in Computer Science (including subseries Lecture
Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). CONCUR:
Concurrency Theory, LNCS, vol. 8704, 249–265.'
mla: 'Hermanns, Holger, et al. “Probabilistic Bisimulation: Naturally on Distributions.”
Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial
Intelligence and Lecture Notes in Bioinformatics), edited by Paolo Baldan
and Daniele Gorla, vol. 8704, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2014, pp. 249–65, doi:10.1007/978-3-662-44584-6_18.'
short: H. Hermanns, J. Krčál, J. Kretinsky, in:, P. Baldan, D. Gorla (Eds.), Lecture
Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence
and Lecture Notes in Bioinformatics), Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2014, pp. 249–265.
conference:
end_date: 2014-09-05
location: Rome, Italy
name: 'CONCUR: Concurrency Theory'
start_date: 2014-09-02
date_created: 2018-12-11T11:55:27Z
date_published: 2014-09-01T00:00:00Z
date_updated: 2021-01-12T06:55:00Z
day: '01'
department:
- _id: ToHe
- _id: KrCh
doi: 10.1007/978-3-662-44584-6_18
ec_funded: 1
editor:
- first_name: Paolo
full_name: Baldan, Paolo
last_name: Baldan
- first_name: Daniele
full_name: Gorla, Daniele
last_name: Gorla
intvolume: ' 8704'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1404.5084
month: '09'
oa: 1
oa_version: Submitted Version
page: 249 - 265
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
publication: Lecture Notes in Computer Science (including subseries Lecture Notes
in Artificial Intelligence and Lecture Notes in Bioinformatics)
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '4993'
status: public
title: 'Probabilistic bisimulation: Naturally on distributions'
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 8704
year: '2014'
...
---
_id: '2054'
abstract:
- lang: eng
text: 'We study two-player concurrent games on finite-state graphs played for an
infinite number of rounds, where in each round, the two players (player 1 and
player 2) choose their moves independently and simultaneously; the current state
and the two moves determine the successor state. The objectives are ω-regular
winning conditions specified as parity objectives. We consider the qualitative
analysis problems: the computation of the almost-sure and limit-sure winning set
of states, where player 1 can ensure to win with probability 1 and with probability
arbitrarily close to 1, respectively. In general the almost-sure and limit-sure
winning strategies require both infinite-memory as well as infinite-precision
(to describe probabilities). While the qualitative analysis problem for concurrent
parity games with infinite-memory, infinite-precision randomized strategies was
studied before, we study the bounded-rationality problem for qualitative analysis
of concurrent parity games, where the strategy set for player 1 is restricted
to bounded-resource strategies. In terms of precision, strategies can be deterministic,
uniform, finite-precision, or infinite-precision; and in terms of memory, strategies
can be memoryless, finite-memory, or infinite-memory. We present a precise and
complete characterization of the qualitative winning sets for all combinations
of classes of strategies. In particular, we show that uniform memoryless strategies
are as powerful as finite-precision infinite-memory strategies, and infinite-precision
memoryless strategies are as powerful as infinite-precision finite-memory strategies.
We show that the winning sets can be computed in (n2d+3) time, where n is the
size of the game structure and 2d is the number of priorities (or colors), and
our algorithms are symbolic. The membership problem of whether a state belongs
to a winning set can be decided in NP ∩ coNP. Our symbolic algorithms are based
on a characterization of the winning sets as μ-calculus formulas, however, our
μ-calculus formulas are crucially different from the ones for concurrent parity
games (without bounded rationality); and our memoryless witness strategy constructions
are significantly different from the infinite-memory witness strategy constructions
for concurrent parity games.'
alternative_title:
- LNCS
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
citation:
ama: 'Chatterjee K. Qualitative concurrent parity games: Bounded rationality. In:
Baldan P, Gorla D, eds. Lecture Notes in Computer Science (Including Subseries
Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).
Vol 8704. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2014:544-559. doi:10.1007/978-3-662-44584-6_37'
apa: 'Chatterjee, K. (2014). Qualitative concurrent parity games: Bounded rationality.
In P. Baldan & D. Gorla (Eds.), Lecture Notes in Computer Science (including
subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
(Vol. 8704, pp. 544–559). Rome, Italy: Schloss Dagstuhl - Leibniz-Zentrum für
Informatik. https://doi.org/10.1007/978-3-662-44584-6_37'
chicago: 'Chatterjee, Krishnendu. “Qualitative Concurrent Parity Games: Bounded
Rationality.” In Lecture Notes in Computer Science (Including Subseries Lecture
Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), edited
by Paolo Baldan and Daniele Gorla, 8704:544–59. Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2014. https://doi.org/10.1007/978-3-662-44584-6_37.'
ieee: 'K. Chatterjee, “Qualitative concurrent parity games: Bounded rationality,”
in Lecture Notes in Computer Science (including subseries Lecture Notes in
Artificial Intelligence and Lecture Notes in Bioinformatics), Rome, Italy,
2014, vol. 8704, pp. 544–559.'
ista: 'Chatterjee K. 2014. Qualitative concurrent parity games: Bounded rationality.
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial
Intelligence and Lecture Notes in Bioinformatics). CONCUR: Concurrency Theory,
LNCS, vol. 8704, 544–559.'
mla: 'Chatterjee, Krishnendu. “Qualitative Concurrent Parity Games: Bounded Rationality.”
Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial
Intelligence and Lecture Notes in Bioinformatics), edited by Paolo Baldan
and Daniele Gorla, vol. 8704, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2014, pp. 544–59, doi:10.1007/978-3-662-44584-6_37.'
short: K. Chatterjee, in:, P. Baldan, D. Gorla (Eds.), Lecture Notes in Computer
Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture
Notes in Bioinformatics), Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2014,
pp. 544–559.
conference:
end_date: 2014-09-05
location: Rome, Italy
name: 'CONCUR: Concurrency Theory'
start_date: 2014-09-02
date_created: 2018-12-11T11:55:27Z
date_published: 2014-09-01T00:00:00Z
date_updated: 2023-02-23T11:23:36Z
day: '01'
department:
- _id: KrCh
doi: 10.1007/978-3-662-44584-6_37
ec_funded: 1
editor:
- first_name: Paolo
full_name: Baldan, Paolo
last_name: Baldan
- first_name: Daniele
full_name: Gorla, Daniele
last_name: Gorla
intvolume: ' 8704'
language:
- iso: eng
month: '09'
oa_version: None
page: 544 - 559
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Lecture Notes in Computer Science (including subseries Lecture Notes
in Artificial Intelligence and Lecture Notes in Bioinformatics)
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '4992'
quality_controlled: '1'
related_material:
record:
- id: '3354'
relation: earlier_version
status: public
status: public
title: 'Qualitative concurrent parity games: Bounded rationality'
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 8704
year: '2014'
...
---
_id: '2056'
abstract:
- lang: eng
text: 'We consider a continuous-time Markov chain (CTMC) whose state space is partitioned
into aggregates, and each aggregate is assigned a probability measure. A sufficient
condition for defining a CTMC over the aggregates is presented as a variant of
weak lumpability, which also characterizes that the measure over the original
process can be recovered from that of the aggregated one. We show how the applicability
of de-aggregation depends on the initial distribution. The application section
is devoted to illustrate how the developed theory aids in reducing CTMC models
of biochemical systems particularly in connection to protein-protein interactions.
We assume that the model is written by a biologist in form of site-graph-rewrite
rules. Site-graph-rewrite rules compactly express that, often, only a local context
of a protein (instead of a full molecular species) needs to be in a certain configuration
in order to trigger a reaction event. This observation leads to suitable aggregate
Markov chains with smaller state spaces, thereby providing sufficient reduction
in computational complexity. This is further exemplified in two case studies:
simple unbounded polymerization and early EGFR/insulin crosstalk.'
acknowledgement: T. Petrov is supported by SystemsX.ch—the Swiss Inititative for Systems
Biology.
author:
- first_name: Arnab
full_name: Ganguly, Arnab
last_name: Ganguly
- first_name: Tatjana
full_name: Petrov, Tatjana
id: 3D5811FC-F248-11E8-B48F-1D18A9856A87
last_name: Petrov
orcid: 0000-0002-9041-0905
- first_name: Heinz
full_name: Koeppl, Heinz
last_name: Koeppl
citation:
ama: Ganguly A, Petrov T, Koeppl H. Markov chain aggregation and its applications
to combinatorial reaction networks. Journal of Mathematical Biology. 2014;69(3):767-797.
doi:10.1007/s00285-013-0738-7
apa: Ganguly, A., Petrov, T., & Koeppl, H. (2014). Markov chain aggregation
and its applications to combinatorial reaction networks. Journal of Mathematical
Biology. Springer. https://doi.org/10.1007/s00285-013-0738-7
chicago: Ganguly, Arnab, Tatjana Petrov, and Heinz Koeppl. “Markov Chain Aggregation
and Its Applications to Combinatorial Reaction Networks.” Journal of Mathematical
Biology. Springer, 2014. https://doi.org/10.1007/s00285-013-0738-7.
ieee: A. Ganguly, T. Petrov, and H. Koeppl, “Markov chain aggregation and its applications
to combinatorial reaction networks,” Journal of Mathematical Biology, vol.
69, no. 3. Springer, pp. 767–797, 2014.
ista: Ganguly A, Petrov T, Koeppl H. 2014. Markov chain aggregation and its applications
to combinatorial reaction networks. Journal of Mathematical Biology. 69(3), 767–797.
mla: Ganguly, Arnab, et al. “Markov Chain Aggregation and Its Applications to Combinatorial
Reaction Networks.” Journal of Mathematical Biology, vol. 69, no. 3, Springer,
2014, pp. 767–97, doi:10.1007/s00285-013-0738-7.
short: A. Ganguly, T. Petrov, H. Koeppl, Journal of Mathematical Biology 69 (2014)
767–797.
date_created: 2018-12-11T11:55:28Z
date_published: 2014-11-20T00:00:00Z
date_updated: 2021-01-12T06:55:01Z
day: '20'
department:
- _id: CaGu
- _id: ToHe
doi: 10.1007/s00285-013-0738-7
intvolume: ' 69'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1303.4532
month: '11'
oa: 1
oa_version: Submitted Version
page: 767 - 797
publication: Journal of Mathematical Biology
publication_status: published
publisher: Springer
publist_id: '4990'
quality_controlled: '1'
scopus_import: 1
status: public
title: Markov chain aggregation and its applications to combinatorial reaction networks
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 69
year: '2014'
...
---
_id: '2057'
abstract:
- lang: eng
text: 'In the past few years, a lot of attention has been devoted to multimedia
indexing by fusing multimodal informations. Two kinds of fusion schemes are generally
considered: The early fusion and the late fusion. We focus on late classifier
fusion, where one combines the scores of each modality at the decision level.
To tackle this problem, we investigate a recent and elegant well-founded quadratic
program named MinCq coming from the machine learning PAC-Bayesian theory. MinCq
looks for the weighted combination, over a set of real-valued functions seen as
voters, leading to the lowest misclassification rate, while maximizing the voters’
diversity. We propose an extension of MinCq tailored to multimedia indexing. Our
method is based on an order-preserving pairwise loss adapted to ranking that allows
us to improve Mean Averaged Precision measure while taking into account the diversity
of the voters that we want to fuse. We provide evidence that this method is naturally
adapted to late fusion procedures and confirm the good behavior of our approach
on the challenging PASCAL VOC’07 benchmark.'
alternative_title:
- LNCS
arxiv: 1
author:
- first_name: Emilie
full_name: Morvant, Emilie
id: 4BAC2A72-F248-11E8-B48F-1D18A9856A87
last_name: Morvant
orcid: 0000-0002-8301-7240
- first_name: Amaury
full_name: Habrard, Amaury
last_name: Habrard
- first_name: Stéphane
full_name: Ayache, Stéphane
last_name: Ayache
citation:
ama: 'Morvant E, Habrard A, Ayache S. Majority vote of diverse classifiers for late
fusion. In: Lecture Notes in Computer Science (Including Subseries Lecture
Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol
8621. Springer; 2014:153-162. doi:10.1007/978-3-662-44415-3_16'
apa: 'Morvant, E., Habrard, A., & Ayache, S. (2014). Majority vote of diverse
classifiers for late fusion. In Lecture Notes in Computer Science (including
subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
(Vol. 8621, pp. 153–162). Joensuu, Finland: Springer. https://doi.org/10.1007/978-3-662-44415-3_16'
chicago: Morvant, Emilie, Amaury Habrard, and Stéphane Ayache. “Majority Vote of
Diverse Classifiers for Late Fusion.” In Lecture Notes in Computer Science
(Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes
in Bioinformatics), 8621:153–62. Springer, 2014. https://doi.org/10.1007/978-3-662-44415-3_16.
ieee: E. Morvant, A. Habrard, and S. Ayache, “Majority vote of diverse classifiers
for late fusion,” in Lecture Notes in Computer Science (including subseries
Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics),
Joensuu, Finland, 2014, vol. 8621, pp. 153–162.
ista: 'Morvant E, Habrard A, Ayache S. 2014. Majority vote of diverse classifiers
for late fusion. Lecture Notes in Computer Science (including subseries Lecture
Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). IAPR: International
Workshop on Structural, Syntactic, and Statistical Pattern Recognition, LNCS,
vol. 8621, 153–162.'
mla: Morvant, Emilie, et al. “Majority Vote of Diverse Classifiers for Late Fusion.”
Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial
Intelligence and Lecture Notes in Bioinformatics), vol. 8621, Springer, 2014,
pp. 153–62, doi:10.1007/978-3-662-44415-3_16.
short: E. Morvant, A. Habrard, S. Ayache, in:, Lecture Notes in Computer Science
(Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes
in Bioinformatics), Springer, 2014, pp. 153–162.
conference:
end_date: 2014-08-22
location: Joensuu, Finland
name: 'IAPR: International Workshop on Structural, Syntactic, and Statistical Pattern
Recognition'
start_date: 2014-08-20
date_created: 2018-12-11T11:55:28Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2021-01-12T06:55:01Z
day: '01'
department:
- _id: ChLa
doi: 10.1007/978-3-662-44415-3_16
ec_funded: 1
external_id:
arxiv:
- '1404.7796'
intvolume: ' 8621'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1404.7796
month: '01'
oa: 1
oa_version: Preprint
page: 153 - 162
project:
- _id: 2532554C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '308036'
name: Lifelong Learning of Visual Scene Understanding
publication: Lecture Notes in Computer Science (including subseries Lecture Notes
in Artificial Intelligence and Lecture Notes in Bioinformatics)
publication_status: published
publisher: Springer
publist_id: '4989'
quality_controlled: '1'
scopus_import: 1
status: public
title: Majority vote of diverse classifiers for late fusion
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8621
year: '2014'
...
---
_id: '2058'
abstract:
- lang: eng
text: We present a method for smoothly blending between existing liquid animations.
We introduce a semi-automatic method for matching two existing liquid animations,
which we use to create new fluid motion that plausibly interpolates the input.
Our contributions include a new space-time non-rigid iterative closest point algorithm
that incorporates user guidance, a subsampling technique for efficient registration
of meshes with millions of vertices, and a fast surface extraction algorithm that
produces 3D triangle meshes from a 4D space-time surface. Our technique can be
used to instantly create hundreds of new simulations, or to interactively explore
complex parameter spaces. Our method is guaranteed to produce output that does
not deviate from the input animations, and it generalizes to multiple dimensions.
Because our method runs at interactive rates after the initial precomputation
step, it has potential applications in games and training simulations.
article_number: '137'
article_processing_charge: No
author:
- first_name: Karthik
full_name: Raveendran, Karthik
last_name: Raveendran
- first_name: Christopher J
full_name: Wojtan, Christopher J
id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
last_name: Wojtan
orcid: 0000-0001-6646-5546
- first_name: Nils
full_name: Thuerey, Nils
last_name: Thuerey
- first_name: Greg
full_name: Türk, Greg
last_name: Türk
citation:
ama: 'Raveendran K, Wojtan C, Thuerey N, Türk G. Blending liquids. In: ACM Transactions
on Graphics. Vol 33. ACM; 2014. doi:10.1145/2601097.2601126'
apa: 'Raveendran, K., Wojtan, C., Thuerey, N., & Türk, G. (2014). Blending liquids.
In ACM Transactions on Graphics (Vol. 33). Vancouver, Canada: ACM. https://doi.org/10.1145/2601097.2601126'
chicago: Raveendran, Karthik, Chris Wojtan, Nils Thuerey, and Greg Türk. “Blending
Liquids.” In ACM Transactions on Graphics, Vol. 33. ACM, 2014. https://doi.org/10.1145/2601097.2601126.
ieee: K. Raveendran, C. Wojtan, N. Thuerey, and G. Türk, “Blending liquids,” in
ACM Transactions on Graphics, Vancouver, Canada, 2014, vol. 33, no. 4.
ista: 'Raveendran K, Wojtan C, Thuerey N, Türk G. 2014. Blending liquids. ACM Transactions
on Graphics. SIGGRAPH: International Conference and Exhibition on Computer Graphics
and Interactive Techniques vol. 33, 137.'
mla: Raveendran, Karthik, et al. “Blending Liquids.” ACM Transactions on Graphics,
vol. 33, no. 4, 137, ACM, 2014, doi:10.1145/2601097.2601126.
short: K. Raveendran, C. Wojtan, N. Thuerey, G. Türk, in:, ACM Transactions on Graphics,
ACM, 2014.
conference:
end_date: 2014-08-14
location: Vancouver, Canada
name: 'SIGGRAPH: International Conference and Exhibition on Computer Graphics and
Interactive Techniques'
start_date: 2014-08-10
date_created: 2018-12-11T11:55:28Z
date_published: 2014-07-01T00:00:00Z
date_updated: 2022-08-25T14:02:46Z
day: '01'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1145/2601097.2601126
file:
- access_level: open_access
checksum: 1752760a2e71e254537f31c0d10d9c6c
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:27Z
date_updated: 2020-07-14T12:45:27Z
file_id: '4688'
file_name: IST-2016-606-v1+1_BlendingLiquids-Preprint.pdf
file_size: 8387384
relation: main_file
file_date_updated: 2020-07-14T12:45:27Z
has_accepted_license: '1'
intvolume: ' 33'
issue: '4'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Submitted Version
project:
- _id: 25636330-B435-11E9-9278-68D0E5697425
grant_number: 11-NSF-1070
name: ROOTS Genome-wide Analysis of Root Traits
publication: ACM Transactions on Graphics
publication_status: published
publisher: ACM
publist_id: '4988'
pubrep_id: '606'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Blending liquids
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 33
year: '2014'
...
---
_id: '2059'
abstract:
- lang: eng
text: Plant embryogenesis is regulated by differential distribution of the plant
hormone auxin. However, the cells establishing these gradients during microspore
embryogenesis remain to be identified. For the first time, we describe, using
the DR5 or DR5rev reporter gene systems, the GFP- and GUS-based auxin biosensors
to monitor auxin during Brassica napus androgenesis at cellular resolution in
the initial stages. Our study provides evidence that the distribution of auxin
changes during embryo development and depends on the temperature-inducible in
vitro culture conditions. For this, microspores (mcs) were induced to embryogenesis
by heat treatment and then subjected to genetic modification via Agrobacterium
tumefaciens. The duration of high temperature treatment had a significant influence
on auxin distribution in isolated and in vitro-cultured microspores and on microspore-derived
embryo development. In the “mild” heat-treated (1 day at 32 °C) mcs, auxin localized
in a polar way already at the uni-nucleate microspore, which was critical for
the initiation of embryos with suspensor-like structure. Assuming a mean mcs radius
of 20 μm, endogenous auxin content in a single cell corresponded to concentration
of 1.01 μM. In mcs subjected to a prolonged heat (5 days at 32 °C), although auxin
concentration increased dozen times, auxin polarization was set up at a few-celled
pro-embryos without suspensor. Those embryos were enclosed in the outer wall called
the exine. The exine rupture was accompanied by the auxin gradient polarization.
Relative quantitative estimation of auxin, using time-lapse imaging, revealed
that primordia possess up to 1.3-fold higher amounts than those found in the root
apices of transgenic MDEs in the presence of exogenous auxin. Our results show,
for the first time, which concentration of endogenous auxin coincides with the
first cell division and how the high temperature interplays with auxin, by what
affects delay early establishing microspore polarity. Moreover, we present how
the local auxin accumulation demonstrates the apical–basal axis formation of the
androgenic embryo and directs the axiality of the adult haploid plant.
acknowledgement: The research was supported by the IPP PAS-IPGB SAS bilateral project
(“Molecular analysis of auxin distribution in oilseed androgenic embryos”), IPP
PAS-FWO VIB bilateral project (“Auxin as signaling molecule in doubled haploid production
of rape (B. napus var. oleifera)”), individual national research project 2011/01/D/NZ9/02547,
and VEGA 2-0090-14.
author:
- first_name: Ewa
full_name: Dubas, Ewa
last_name: Dubas
- first_name: Jana
full_name: Moravčíková, Jana
last_name: Moravčíková
- first_name: Jana
full_name: Libantová, Jana
last_name: Libantová
- first_name: Ildikó
full_name: Matušíková, Ildikó
last_name: Matušíková
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Iwona
full_name: Zur, Iwona
last_name: Zur
- first_name: Monika
full_name: Krzewska, Monika
last_name: Krzewska
citation:
ama: Dubas E, Moravčíková J, Libantová J, et al. The influence of heat stress on
auxin distribution in transgenic B napus microspores and microspore derived embryos.
Protoplasma. 2014;251(5):1077-1087. doi:10.1007/s00709-014-0616-1
apa: Dubas, E., Moravčíková, J., Libantová, J., Matušíková, I., Benková, E., Zur,
I., & Krzewska, M. (2014). The influence of heat stress on auxin distribution
in transgenic B napus microspores and microspore derived embryos. Protoplasma.
Springer. https://doi.org/10.1007/s00709-014-0616-1
chicago: Dubas, Ewa, Jana Moravčíková, Jana Libantová, Ildikó Matušíková, Eva Benková,
Iwona Zur, and Monika Krzewska. “The Influence of Heat Stress on Auxin Distribution
in Transgenic B Napus Microspores and Microspore Derived Embryos.” Protoplasma.
Springer, 2014. https://doi.org/10.1007/s00709-014-0616-1.
ieee: E. Dubas et al., “The influence of heat stress on auxin distribution
in transgenic B napus microspores and microspore derived embryos,” Protoplasma,
vol. 251, no. 5. Springer, pp. 1077–1087, 2014.
ista: Dubas E, Moravčíková J, Libantová J, Matušíková I, Benková E, Zur I, Krzewska
M. 2014. The influence of heat stress on auxin distribution in transgenic B napus
microspores and microspore derived embryos. Protoplasma. 251(5), 1077–1087.
mla: Dubas, Ewa, et al. “The Influence of Heat Stress on Auxin Distribution in Transgenic
B Napus Microspores and Microspore Derived Embryos.” Protoplasma, vol.
251, no. 5, Springer, 2014, pp. 1077–87, doi:10.1007/s00709-014-0616-1.
short: E. Dubas, J. Moravčíková, J. Libantová, I. Matušíková, E. Benková, I. Zur,
M. Krzewska, Protoplasma 251 (2014) 1077–1087.
date_created: 2018-12-11T11:55:29Z
date_published: 2014-02-20T00:00:00Z
date_updated: 2021-01-12T06:55:02Z
day: '20'
ddc:
- '580'
department:
- _id: EvBe
doi: 10.1007/s00709-014-0616-1
file:
- access_level: open_access
checksum: d570a6073765118fc0bb83c31d96fa53
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:18:31Z
date_updated: 2020-07-14T12:45:27Z
file_id: '5353'
file_name: IST-2015-394-v1+1_s00709-014-0616-1.pdf
file_size: 6377990
relation: main_file
file_date_updated: 2020-07-14T12:45:27Z
has_accepted_license: '1'
intvolume: ' 251'
issue: '5'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 1077 - 1087
publication: Protoplasma
publication_status: published
publisher: Springer
publist_id: '4987'
pubrep_id: '394'
quality_controlled: '1'
scopus_import: 1
status: public
title: The influence of heat stress on auxin distribution in transgenic B napus microspores
and microspore derived embryos
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 251
year: '2014'
...
---
_id: '2061'
abstract:
- lang: eng
text: 'Development of cambium and its activity is important for our knowledge of
the mechanism of secondary growth. Arabidopsis thaliana emerges as a good model
plant for such a kind of study. Thus, this paper reports on cellular events taking
place in the interfascicular regions of inflorescence stems of A. thaliana, leading
to the development of interfascicular cambium from differentiated interfascicular
parenchyma cells (IPC). These events are as follows: appearance of auxin accumulation,
PIN1 gene expression, polar PIN1 protein localization in the basal plasma membrane
and periclinal divisions. Distribution of auxin was observed to be higher in differentiating
into cambium parenchyma cells compared to cells within the pith and cortex. Expression
of PIN1 in IPC was always preceded by auxin accumulation. Basal localization of
PIN1 was already established in the cells prior to their periclinal division.
These cellular events initiated within parenchyma cells adjacent to the vascular
bundles and successively extended from that point towards the middle region of
the interfascicular area, located between neighboring vascular bundles. The final
consequence of which was the closure of the cambial ring within the stem. Changes
in the chemical composition of IPC walls were also detected and included changes
of pectic epitopes, xyloglucans (XG) and extensins rich in hydroxyproline (HRGPs).
In summary, results presented in this paper describe interfascicular cambium ontogenesis
in terms of successive cellular events in the interfascicular regions of inflorescence
stems of Arabidopsis.'
author:
- first_name: Ewa
full_name: Mazur, Ewa
last_name: Mazur
- first_name: Ewa
full_name: Kurczyñska, Ewa
last_name: Kurczyñska
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Mazur E, Kurczyñska E, Friml J. Cellular events during interfascicular cambium
ontogenesis in inflorescence stems of Arabidopsis. Protoplasma. 2014;251(5):1125-1139.
doi:10.1007/s00709-014-0620-5
apa: Mazur, E., Kurczyñska, E., & Friml, J. (2014). Cellular events during interfascicular
cambium ontogenesis in inflorescence stems of Arabidopsis. Protoplasma.
Springer. https://doi.org/10.1007/s00709-014-0620-5
chicago: Mazur, Ewa, Ewa Kurczyñska, and Jiří Friml. “Cellular Events during Interfascicular
Cambium Ontogenesis in Inflorescence Stems of Arabidopsis.” Protoplasma.
Springer, 2014. https://doi.org/10.1007/s00709-014-0620-5.
ieee: E. Mazur, E. Kurczyñska, and J. Friml, “Cellular events during interfascicular
cambium ontogenesis in inflorescence stems of Arabidopsis,” Protoplasma,
vol. 251, no. 5. Springer, pp. 1125–1139, 2014.
ista: Mazur E, Kurczyñska E, Friml J. 2014. Cellular events during interfascicular
cambium ontogenesis in inflorescence stems of Arabidopsis. Protoplasma. 251(5),
1125–1139.
mla: Mazur, Ewa, et al. “Cellular Events during Interfascicular Cambium Ontogenesis
in Inflorescence Stems of Arabidopsis.” Protoplasma, vol. 251, no. 5, Springer,
2014, pp. 1125–39, doi:10.1007/s00709-014-0620-5.
short: E. Mazur, E. Kurczyñska, J. Friml, Protoplasma 251 (2014) 1125–1139.
date_created: 2018-12-11T11:55:29Z
date_published: 2014-02-14T00:00:00Z
date_updated: 2021-01-12T06:55:03Z
day: '14'
department:
- _id: JiFr
doi: 10.1007/s00709-014-0620-5
intvolume: ' 251'
issue: '5'
language:
- iso: eng
month: '02'
oa_version: None
page: 1125 - 1139
publication: Protoplasma
publication_status: published
publisher: Springer
publist_id: '4985'
quality_controlled: '1'
scopus_import: 1
status: public
title: Cellular events during interfascicular cambium ontogenesis in inflorescence
stems of Arabidopsis
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 251
year: '2014'
...
---
_id: '2062'
abstract:
- lang: eng
text: The success story of fast-spiking, parvalbumin-positive (PV+) GABAergic interneurons
(GABA, γ-aminobutyric acid) in the mammalian central nervous system is noteworthy.
In 1995, the properties of these interneurons were completely unknown. Twenty
years later, thanks to the massive use of subcellular patch-clamp techniques,
simultaneous multiple-cell recording, optogenetics, in vivo measurements, and
computational approaches, our knowledge about PV+ interneurons became more extensive
than for several types of pyramidal neurons. These findings have implications
beyond the “small world” of basic research on GABAergic cells. For example, the
results provide a first proof of principle that neuroscientists might be able
to close the gaps between the molecular, cellular, network, and behavioral levels,
representing one of the main challenges at the present time. Furthermore, the
results may form the basis for PV+ interneurons as therapeutic targets for brain
disease in the future. However, much needs to be learned about the basic function
of these interneurons before clinical neuroscientists will be able to use PV+
interneurons for therapeutic purposes.
article_number: '1255263'
author:
- first_name: Hua
full_name: Hu, Hua
id: 4AC0145C-F248-11E8-B48F-1D18A9856A87
last_name: Hu
- first_name: Jian
full_name: Gan, Jian
id: 3614E438-F248-11E8-B48F-1D18A9856A87
last_name: Gan
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: 'Hu H, Gan J, Jonas PM. Fast-spiking parvalbumin^+ GABAergic interneurons:
From cellular design to microcircuit function. Science. 2014;345(6196).
doi:10.1126/science.1255263'
apa: 'Hu, H., Gan, J., & Jonas, P. M. (2014). Fast-spiking parvalbumin^+ GABAergic
interneurons: From cellular design to microcircuit function. Science. American
Association for the Advancement of Science. https://doi.org/10.1126/science.1255263'
chicago: 'Hu, Hua, Jian Gan, and Peter M Jonas. “Fast-Spiking Parvalbumin^+ GABAergic
Interneurons: From Cellular Design to Microcircuit Function.” Science.
American Association for the Advancement of Science, 2014. https://doi.org/10.1126/science.1255263.'
ieee: 'H. Hu, J. Gan, and P. M. Jonas, “Fast-spiking parvalbumin^+ GABAergic interneurons:
From cellular design to microcircuit function,” Science, vol. 345, no.
6196. American Association for the Advancement of Science, 2014.'
ista: 'Hu H, Gan J, Jonas PM. 2014. Fast-spiking parvalbumin^+ GABAergic interneurons:
From cellular design to microcircuit function. Science. 345(6196), 1255263.'
mla: 'Hu, Hua, et al. “Fast-Spiking Parvalbumin^+ GABAergic Interneurons: From Cellular
Design to Microcircuit Function.” Science, vol. 345, no. 6196, 1255263,
American Association for the Advancement of Science, 2014, doi:10.1126/science.1255263.'
short: H. Hu, J. Gan, P.M. Jonas, Science 345 (2014).
date_created: 2018-12-11T11:55:29Z
date_published: 2014-08-01T00:00:00Z
date_updated: 2021-01-12T06:55:03Z
day: '01'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1126/science.1255263
ec_funded: 1
file:
- access_level: open_access
checksum: a0036a589037d37e86364fa25cc0a82f
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:00Z
date_updated: 2020-07-14T12:45:27Z
file_id: '5185'
file_name: IST-2017-821-v1+1_1255263JonasPVReviewTextR_Final.pdf
file_size: 215514
relation: main_file
- access_level: open_access
checksum: e1f57d2713725449cb898fdcb8ef47b8
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:01Z
date_updated: 2020-07-14T12:45:27Z
file_id: '5186'
file_name: IST-2017-821-v1+2_1255263JonasPVReviewFigures_Final.pdf
file_size: 1732723
relation: main_file
file_date_updated: 2020-07-14T12:45:27Z
has_accepted_license: '1'
intvolume: ' 345'
issue: '6196'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Submitted Version
project:
- _id: 25C26B1E-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P24909-B24
name: Mechanisms of transmitter release at GABAergic synapses
- _id: 25C0F108-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '268548'
name: Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '4984'
pubrep_id: '821'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Fast-spiking parvalbumin^+ GABAergic interneurons: From cellular design to
microcircuit function'
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 345
year: '2014'
...
---
_id: '2063'
abstract:
- lang: eng
text: We consider Markov decision processes (MDPs) which are a standard model for
probabilistic systems.We focus on qualitative properties forMDPs that can express
that desired behaviors of the system arise almost-surely (with probability 1)
or with positive probability. We introduce a new simulation relation to capture
the refinement relation ofMDPs with respect to qualitative properties, and present
discrete graph theoretic algorithms with quadratic complexity to compute the simulation
relation.We present an automated technique for assume-guarantee style reasoning
for compositional analysis ofMDPs with qualitative properties by giving a counterexample
guided abstraction-refinement approach to compute our new simulation relation.
We have implemented our algorithms and show that the compositional analysis leads
to significant improvements.
alternative_title:
- LNCS
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Chmelik, Martin
id: 3624234E-F248-11E8-B48F-1D18A9856A87
last_name: Chmelik
- first_name: Przemyslaw
full_name: Daca, Przemyslaw
id: 49351290-F248-11E8-B48F-1D18A9856A87
last_name: Daca
citation:
ama: 'Chatterjee K, Chmelik M, Daca P. CEGAR for qualitative analysis of probabilistic
systems. In: Vol 8559. Springer; 2014:473-490. doi:10.1007/978-3-319-08867-9_31'
apa: 'Chatterjee, K., Chmelik, M., & Daca, P. (2014). CEGAR for qualitative
analysis of probabilistic systems (Vol. 8559, pp. 473–490). Presented at the CAV:
Computer Aided Verification, Vienna, Austria: Springer. https://doi.org/10.1007/978-3-319-08867-9_31'
chicago: Chatterjee, Krishnendu, Martin Chmelik, and Przemyslaw Daca. “CEGAR for
Qualitative Analysis of Probabilistic Systems,” 8559:473–90. Springer, 2014. https://doi.org/10.1007/978-3-319-08867-9_31.
ieee: 'K. Chatterjee, M. Chmelik, and P. Daca, “CEGAR for qualitative analysis of
probabilistic systems,” presented at the CAV: Computer Aided Verification, Vienna,
Austria, 2014, vol. 8559, pp. 473–490.'
ista: 'Chatterjee K, Chmelik M, Daca P. 2014. CEGAR for qualitative analysis of
probabilistic systems. CAV: Computer Aided Verification, LNCS, vol. 8559, 473–490.'
mla: Chatterjee, Krishnendu, et al. CEGAR for Qualitative Analysis of Probabilistic
Systems. Vol. 8559, Springer, 2014, pp. 473–90, doi:10.1007/978-3-319-08867-9_31.
short: K. Chatterjee, M. Chmelik, P. Daca, in:, Springer, 2014, pp. 473–490.
conference:
end_date: 2014-07-22
location: Vienna, Austria
name: 'CAV: Computer Aided Verification'
start_date: 2014-07-18
date_created: 2018-12-11T11:55:30Z
date_published: 2014-07-01T00:00:00Z
date_updated: 2023-09-07T11:58:33Z
day: '01'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1007/978-3-319-08867-9_31
ec_funded: 1
intvolume: ' 8559'
language:
- iso: eng
month: '07'
oa_version: None
page: 473 - 490
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
publication_status: published
publisher: Springer
publist_id: '4978'
quality_controlled: '1'
related_material:
record:
- id: '5412'
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status: public
- id: '5413'
relation: earlier_version
status: public
- id: '5414'
relation: earlier_version
status: public
- id: '1155'
relation: dissertation_contains
status: public
status: public
title: CEGAR for qualitative analysis of probabilistic systems
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8559
year: '2014'
...
---
_id: '2064'
abstract:
- lang: eng
text: We examined the synaptic structure, quantity, and distribution of α-amino-3-hydroxy-5-methylisoxazole-4-propionic
acid (AMPA)- and N-methyl-D-aspartate (NMDA)-type glutamate receptors (AMPARs
and NMDARs, respectively) in rat cochlear nuclei by a highly sensitive freeze-fracture
replica labeling technique. Four excitatory synapses formed by two distinct inputs,
auditory nerve (AN) and parallel fibers (PF), on different cell types were analyzed.
These excitatory synapse types included AN synapses on bushy cells (AN-BC synapses)
and fusiform cells (AN-FC synapses) and PF synapses on FC (PF-FC synapses) and
cartwheel cell spines (PF-CwC synapses). Immunogold labeling revealed differences
in synaptic structure as well as AMPAR and NMDAR number and/or density in both
AN and PF synapses, indicating a target-dependent organization. The immunogold
receptor labeling also identified differences in the synaptic organization of
FCs based on AN or PF connections, indicating an input-dependent organization
in FCs. Among the four excitatory synapse types, the AN-BC synapses were the smallest
and had the most densely packed intramembrane particles (IMPs), whereas the PF-CwC
synapses were the largest and had sparsely packed IMPs. All four synapse types
showed positive correlations between the IMP-cluster area and the AMPAR number,
indicating a common intrasynapse-type relationship for glutamatergic synapses.
Immunogold particles for AMPARs were distributed over the entire area of individual
AN synapses; PF synapses often showed synaptic areas devoid of labeling. The gold-labeling
for NMDARs occurred in a mosaic fashion, with less positive correlations between
the IMP-cluster area and the NMDAR number. Our observations reveal target- and
input-dependent features in the structure, number, and organization of AMPARs
and NMDARs in AN and PF synapses.
acknowledgement: "National Institutes of Health (NIH) Grant Number: 1R01DC013048‐0;
Biotechnology and Biological Sciences Research Council, UK Grant Number: BB/J015938/1\r\n"
author:
- first_name: Maía
full_name: Rubio, Maía
last_name: Rubio
- first_name: Yugo
full_name: Fukazawa, Yugo
last_name: Fukazawa
- first_name: Naomi
full_name: Kamasawa, Naomi
last_name: Kamasawa
- first_name: Cheryl
full_name: Clarkson, Cheryl
last_name: Clarkson
- first_name: Elek
full_name: Molnár, Elek
last_name: Molnár
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Rubio M, Fukazawa Y, Kamasawa N, Clarkson C, Molnár E, Shigemoto R. Target-
and input-dependent organization of AMPA and NMDA receptors in synaptic connections
of the cochlear nucleus. Journal of Comparative Neurology. 2014;522(18):4023-4042.
doi:10.1002/cne.23654
apa: Rubio, M., Fukazawa, Y., Kamasawa, N., Clarkson, C., Molnár, E., & Shigemoto,
R. (2014). Target- and input-dependent organization of AMPA and NMDA receptors
in synaptic connections of the cochlear nucleus. Journal of Comparative Neurology.
Wiley-Blackwell. https://doi.org/10.1002/cne.23654
chicago: Rubio, Maía, Yugo Fukazawa, Naomi Kamasawa, Cheryl Clarkson, Elek Molnár,
and Ryuichi Shigemoto. “Target- and Input-Dependent Organization of AMPA and NMDA
Receptors in Synaptic Connections of the Cochlear Nucleus.” Journal of Comparative
Neurology. Wiley-Blackwell, 2014. https://doi.org/10.1002/cne.23654.
ieee: M. Rubio, Y. Fukazawa, N. Kamasawa, C. Clarkson, E. Molnár, and R. Shigemoto,
“Target- and input-dependent organization of AMPA and NMDA receptors in synaptic
connections of the cochlear nucleus,” Journal of Comparative Neurology,
vol. 522, no. 18. Wiley-Blackwell, pp. 4023–4042, 2014.
ista: Rubio M, Fukazawa Y, Kamasawa N, Clarkson C, Molnár E, Shigemoto R. 2014.
Target- and input-dependent organization of AMPA and NMDA receptors in synaptic
connections of the cochlear nucleus. Journal of Comparative Neurology. 522(18),
4023–4042.
mla: Rubio, Maía, et al. “Target- and Input-Dependent Organization of AMPA and NMDA
Receptors in Synaptic Connections of the Cochlear Nucleus.” Journal of Comparative
Neurology, vol. 522, no. 18, Wiley-Blackwell, 2014, pp. 4023–42, doi:10.1002/cne.23654.
short: M. Rubio, Y. Fukazawa, N. Kamasawa, C. Clarkson, E. Molnár, R. Shigemoto,
Journal of Comparative Neurology 522 (2014) 4023–4042.
date_created: 2018-12-11T11:55:30Z
date_published: 2014-07-29T00:00:00Z
date_updated: 2021-01-12T06:55:05Z
day: '29'
department:
- _id: RySh
doi: 10.1002/cne.23654
intvolume: ' 522'
issue: '18'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198489/
month: '07'
oa: 1
oa_version: Submitted Version
page: 4023 - 4042
publication: Journal of Comparative Neurology
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4974'
quality_controlled: '1'
scopus_import: 1
status: public
title: Target- and input-dependent organization of AMPA and NMDA receptors in synaptic
connections of the cochlear nucleus
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 522
year: '2014'
...
---
_id: '1375'
abstract:
- lang: eng
text: 'We consider directed graphs where each edge is labeled with an integer weight
and study the fundamental algorithmic question of computing the value of a cycle
with minimum mean weight. Our contributions are twofold: (1) First we show that
the algorithmic question is reducible to the problem of a logarithmic number of
min-plus matrix multiplications of n×n-matrices, where n is the number of vertices
of the graph. (2) Second, when the weights are nonnegative, we present the first
(1+ε)-approximation algorithm for the problem and the running time of our algorithm
is Õ(nωlog3(nW/ε)/ε),1 where O(nω) is the time required for the classic n×n-matrix
multiplication and W is the maximum value of the weights. With an additional O(log(nW/ε))
factor in space a cycle with approximately optimal weight can be computed within
the same time bound.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Sebastian
full_name: Krinninger, Sebastian
last_name: Krinninger
- first_name: Veronika
full_name: Loitzenbauer, Veronika
last_name: Loitzenbauer
- first_name: Michael
full_name: Raskin, Michael
last_name: Raskin
citation:
ama: Chatterjee K, Henzinger MH, Krinninger S, Loitzenbauer V, Raskin M. Approximating
the minimum cycle mean. Theoretical Computer Science. 2014;547(C):104-116.
doi:10.1016/j.tcs.2014.06.031
apa: Chatterjee, K., Henzinger, M. H., Krinninger, S., Loitzenbauer, V., & Raskin,
M. (2014). Approximating the minimum cycle mean. Theoretical Computer Science.
Elsevier. https://doi.org/10.1016/j.tcs.2014.06.031
chicago: Chatterjee, Krishnendu, Monika H Henzinger, Sebastian Krinninger, Veronika
Loitzenbauer, and Michael Raskin. “Approximating the Minimum Cycle Mean.” Theoretical
Computer Science. Elsevier, 2014. https://doi.org/10.1016/j.tcs.2014.06.031.
ieee: K. Chatterjee, M. H. Henzinger, S. Krinninger, V. Loitzenbauer, and M. Raskin,
“Approximating the minimum cycle mean,” Theoretical Computer Science, vol.
547, no. C. Elsevier, pp. 104–116, 2014.
ista: Chatterjee K, Henzinger MH, Krinninger S, Loitzenbauer V, Raskin M. 2014.
Approximating the minimum cycle mean. Theoretical Computer Science. 547(C), 104–116.
mla: Chatterjee, Krishnendu, et al. “Approximating the Minimum Cycle Mean.” Theoretical
Computer Science, vol. 547, no. C, Elsevier, 2014, pp. 104–16, doi:10.1016/j.tcs.2014.06.031.
short: K. Chatterjee, M.H. Henzinger, S. Krinninger, V. Loitzenbauer, M. Raskin,
Theoretical Computer Science 547 (2014) 104–116.
date_created: 2018-12-11T11:51:40Z
date_published: 2014-08-28T00:00:00Z
date_updated: 2022-09-09T11:50:58Z
day: '28'
department:
- _id: KrCh
doi: 10.1016/j.tcs.2014.06.031
ec_funded: 1
external_id:
arxiv:
- '1307.4473'
intvolume: ' 547'
issue: C
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1307.4473
month: '08'
oa: 1
oa_version: Preprint
page: 104 - 116
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Theoretical Computer Science
publication_status: published
publisher: Elsevier
publist_id: '5836'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Approximating the minimum cycle mean
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 547
year: '2014'
...
---
_id: '1392'
abstract:
- lang: eng
text: Fault-tolerant distributed algorithms play an important role in ensuring the
reliability of many software applications. In this paper we consider distributed
algorithms whose computations are organized in rounds. To verify the correctness
of such algorithms, we reason about (i) properties (such as invariants) of the
state, (ii) the transitions controlled by the algorithm, and (iii) the communication
graph. We introduce a logic that addresses these points, and contains set comprehensions
with cardinality constraints, function symbols to describe the local states of
each process, and a limited form of quantifier alternation to express the verification
conditions. We show its use in automating the verification of consensus algorithms.
In particular, we give a semi-decision procedure for the unsatisfiability problem
of the logic and identify a decidable fragment. We successfully applied our framework
to verify the correctness of a variety of consensus algorithms tolerant to both
benign faults (message loss, process crashes) and value faults (message corruption).
acknowledgement: Supported by the Vienna Science and Technology Fund (WWTF) through
grant PROSEED.
alternative_title:
- LNCS
author:
- first_name: Cezara
full_name: Dragoi, Cezara
id: 2B2B5ED0-F248-11E8-B48F-1D18A9856A87
last_name: Dragoi
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Helmut
full_name: Veith, Helmut
last_name: Veith
- first_name: Josef
full_name: Widder, Josef
last_name: Widder
- first_name: Damien
full_name: Zufferey, Damien
id: 4397AC76-F248-11E8-B48F-1D18A9856A87
last_name: Zufferey
orcid: 0000-0002-3197-8736
citation:
ama: 'Dragoi C, Henzinger TA, Veith H, Widder J, Zufferey D. A logic-based framework
for verifying consensus algorithms. In: Vol 8318. Springer; 2014:161-181. doi:10.1007/978-3-642-54013-4_10'
apa: 'Dragoi, C., Henzinger, T. A., Veith, H., Widder, J., & Zufferey, D. (2014).
A logic-based framework for verifying consensus algorithms (Vol. 8318, pp. 161–181).
Presented at the VMCAI: Verification, Model Checking and Abstract Interpretation,
San Diego, USA: Springer. https://doi.org/10.1007/978-3-642-54013-4_10'
chicago: Dragoi, Cezara, Thomas A Henzinger, Helmut Veith, Josef Widder, and Damien
Zufferey. “A Logic-Based Framework for Verifying Consensus Algorithms,” 8318:161–81.
Springer, 2014. https://doi.org/10.1007/978-3-642-54013-4_10.
ieee: 'C. Dragoi, T. A. Henzinger, H. Veith, J. Widder, and D. Zufferey, “A logic-based
framework for verifying consensus algorithms,” presented at the VMCAI: Verification,
Model Checking and Abstract Interpretation, San Diego, USA, 2014, vol. 8318, pp.
161–181.'
ista: 'Dragoi C, Henzinger TA, Veith H, Widder J, Zufferey D. 2014. A logic-based
framework for verifying consensus algorithms. VMCAI: Verification, Model Checking
and Abstract Interpretation, LNCS, vol. 8318, 161–181.'
mla: Dragoi, Cezara, et al. A Logic-Based Framework for Verifying Consensus Algorithms.
Vol. 8318, Springer, 2014, pp. 161–81, doi:10.1007/978-3-642-54013-4_10.
short: C. Dragoi, T.A. Henzinger, H. Veith, J. Widder, D. Zufferey, in:, Springer,
2014, pp. 161–181.
conference:
end_date: 2014-01-21
location: San Diego, USA
name: 'VMCAI: Verification, Model Checking and Abstract Interpretation'
start_date: 2014-01-19
date_created: 2018-12-11T11:51:45Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2021-01-12T06:50:22Z
day: '01'
ddc:
- '000'
- '005'
department:
- _id: ToHe
doi: 10.1007/978-3-642-54013-4_10
ec_funded: 1
file:
- access_level: open_access
checksum: bffa33d39be77df0da39defe97eabf84
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:06Z
date_updated: 2020-07-14T12:44:48Z
file_id: '4859'
file_name: IST-2014-179-v1+1_vmcai14.pdf
file_size: 444138
relation: main_file
file_date_updated: 2020-07-14T12:44:48Z
has_accepted_license: '1'
intvolume: ' 8318'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 161 - 181
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
publication_status: published
publisher: Springer
publist_id: '5817'
pubrep_id: '179'
quality_controlled: '1'
scopus_import: 1
status: public
title: A logic-based framework for verifying consensus algorithms
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8318
year: '2014'
...
---
_id: '1393'
abstract:
- lang: eng
text: 'Probabilistic programs are usual functional or imperative programs with two
added constructs: (1) the ability to draw values at random from distributions,
and (2) the ability to condition values of variables in a program via observations.
Models from diverse application areas such as computer vision, coding theory,
cryptographic protocols, biology and reliability analysis can be written as probabilistic
programs. Probabilistic inference is the problem of computing an explicit representation
of the probability distribution implicitly specified by a probabilistic program.
Depending on the application, the desired output from inference may vary-we may
want to estimate the expected value of some function f with respect to the distribution,
or the mode of the distribution, or simply a set of samples drawn from the distribution.
In this paper, we describe connections this research area called \Probabilistic
Programming" has with programming languages and software engineering, and
this includes language design, and the static and dynamic analysis of programs.
We survey current state of the art and speculate on promising directions for future
research.'
article_processing_charge: No
author:
- first_name: Andrew
full_name: Gordon, Andrew
last_name: Gordon
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Aditya
full_name: Nori, Aditya
last_name: Nori
- first_name: Sriram
full_name: Rajamani, Sriram
last_name: Rajamani
citation:
ama: 'Gordon A, Henzinger TA, Nori A, Rajamani S. Probabilistic programming. In:
Proceedings of the on Future of Software Engineering. ACM; 2014:167-181.
doi:10.1145/2593882.2593900'
apa: 'Gordon, A., Henzinger, T. A., Nori, A., & Rajamani, S. (2014). Probabilistic
programming. In Proceedings of the on Future of Software Engineering (pp.
167–181). Hyderabad, India: ACM. https://doi.org/10.1145/2593882.2593900'
chicago: Gordon, Andrew, Thomas A Henzinger, Aditya Nori, and Sriram Rajamani. “Probabilistic
Programming.” In Proceedings of the on Future of Software Engineering,
167–81. ACM, 2014. https://doi.org/10.1145/2593882.2593900.
ieee: A. Gordon, T. A. Henzinger, A. Nori, and S. Rajamani, “Probabilistic programming,”
in Proceedings of the on Future of Software Engineering, Hyderabad, India,
2014, pp. 167–181.
ista: 'Gordon A, Henzinger TA, Nori A, Rajamani S. 2014. Probabilistic programming.
Proceedings of the on Future of Software Engineering. FOSE: Future of Software
Engineering, 167–181.'
mla: Gordon, Andrew, et al. “Probabilistic Programming.” Proceedings of the on
Future of Software Engineering, ACM, 2014, pp. 167–81, doi:10.1145/2593882.2593900.
short: A. Gordon, T.A. Henzinger, A. Nori, S. Rajamani, in:, Proceedings of the
on Future of Software Engineering, ACM, 2014, pp. 167–181.
conference:
end_date: 2014-06-07
location: Hyderabad, India
name: 'FOSE: Future of Software Engineering'
start_date: 2014-05-31
date_created: 2018-12-11T11:51:45Z
date_published: 2014-05-31T00:00:00Z
date_updated: 2021-01-12T06:50:22Z
day: '31'
department:
- _id: ToHe
doi: 10.1145/2593882.2593900
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1145/2593882.2593900
month: '05'
oa: 1
oa_version: Published Version
page: 167 - 181
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication: Proceedings of the on Future of Software Engineering
publication_status: published
publisher: ACM
publist_id: '5816'
quality_controlled: '1'
scopus_import: 1
status: public
title: Probabilistic programming
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2014'
...
---
_id: '1395'
abstract:
- lang: eng
text: In this thesis I studied various individual and social immune defences employed
by the invasive garden ant Lasius neglectus mostly against entomopathogenic fungi. The
first two chapters of this thesis address the phenomenon of 'social immunisation'.
Social immunisation, that is the immunological protection of group members due
to social contact to a pathogen-exposed nestmate, has been described in various
social insect species against different types of pathogens. However, in the case
of entomopathogenic fungi it has, so far, only been demonstrated that social immunisation
exists at all. Its underlying mechanisms r any other properties were, however,
unknown. In the first chapter of this thesis I identified the mechanistic basis
of social immunisation in L. neglectus against the entomopathogenous fungus Metarhizium.
I could show that nestmates of a pathogen-exposed individual contract low-level
infections due to social interactions. These low-level infections are, however,
non-lethal and cause an active stimulation of the immune system, which protects
the nestmates upon subsequent pathogen encounters. In the second chapter of this
thesis I investigated the specificity and colony level effects of social immunisation.
I demonstrated that the protection conferred by social immunisation is highly
specific, protecting ants only against the same pathogen strain. In addition,
depending on the respective context, social immunisation may even cause fitness
costs. I further showed that social immunisation crucially affects sanitary behaviour
and disease dynamics within ant groups. In the third chapter of this thesis I
studied the effects of the ectosymbiotic fungus Laboulbenia formicarum on its
host L. neglectus. Although Laboulbeniales are the largest order of insect-parasitic
fungi, research concerning host fitness consequence is sparse. I showed that highly
Laboulbenia-infected ants sustain fitness costs under resource limitation, however,
gain fitness benefits when exposed to an entomopathogenus fungus. These effects
are probably cause by a prophylactic upregulation of behavioural as well as physiological
immune defences in highly infected ants.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Matthias
full_name: Konrad, Matthias
id: 46528076-F248-11E8-B48F-1D18A9856A87
last_name: Konrad
citation:
ama: 'Konrad M. Immune defences in ants: Effects of social immunisation and a fungal
ectosymbiont in the ant Lasius neglectus. 2014.'
apa: 'Konrad, M. (2014). Immune defences in ants: Effects of social immunisation
and a fungal ectosymbiont in the ant Lasius neglectus. Institute of Science
and Technology Austria.'
chicago: 'Konrad, Matthias. “Immune Defences in Ants: Effects of Social Immunisation
and a Fungal Ectosymbiont in the Ant Lasius Neglectus.” Institute of Science and
Technology Austria, 2014.'
ieee: 'M. Konrad, “Immune defences in ants: Effects of social immunisation and a
fungal ectosymbiont in the ant Lasius neglectus,” Institute of Science and Technology
Austria, 2014.'
ista: 'Konrad M. 2014. Immune defences in ants: Effects of social immunisation and
a fungal ectosymbiont in the ant Lasius neglectus. Institute of Science and Technology
Austria.'
mla: 'Konrad, Matthias. Immune Defences in Ants: Effects of Social Immunisation
and a Fungal Ectosymbiont in the Ant Lasius Neglectus. Institute of Science
and Technology Austria, 2014.'
short: 'M. Konrad, Immune Defences in Ants: Effects of Social Immunisation and a
Fungal Ectosymbiont in the Ant Lasius Neglectus, Institute of Science and Technology
Austria, 2014.'
date_created: 2018-12-11T11:51:46Z
date_published: 2014-02-01T00:00:00Z
date_updated: 2023-09-07T11:38:56Z
day: '01'
degree_awarded: PhD
department:
- _id: SyCr
language:
- iso: eng
month: '02'
oa_version: None
page: '131'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '5814'
status: public
supervisor:
- first_name: Sylvia M
full_name: Cremer, Sylvia M
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
title: 'Immune defences in ants: Effects of social immunisation and a fungal ectosymbiont
in the ant Lasius neglectus'
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2014'
...
---
_id: '1402'
abstract:
- lang: eng
text: Phosphatidylinositol (Ptdlns) is a structural phospholipid that can be phosphorylated
into various lipid signaling molecules, designated polyphosphoinositides (PPIs).
The reversible phosphorylation of PPIs on the 3, 4, or 5 position of inositol
is performed by a set of organelle-specific kinases and phosphatases, and the
characteristic head groups make these molecules ideal for regulating biological
processes in time and space. In yeast and mammals, Ptdlns3P and Ptdlns(3,5)P2
play crucial roles in trafficking toward the lytic compartments, whereas the role
in plants is not yet fully understood. Here we identified the role of a land plant-specific
subgroup of PPI phosphatases, the suppressor of actin 2 (SAC2) to SAC5, during
vauolar trafficking and morphogenesis in Arabidopsis thaliana. SAC2-SAC5 localize
to the tonoplast along with Ptdlns3P, the presumable product of their activity.
in SAC gain- and loss-of-function mutants, the levels of Ptdlns monophosphates
and bisphosphates were changed, with opposite effects on the morphology of storage
and lytic vacuoles, and the trafficking toward the vacuoles was defective. Moreover,
multiple sac knockout mutants had an increased number of smaller storage and lytic
vacuoles, whereas extralarge vacuoles were observed in the overexpression lines,
correlating with various growth and developmental defects. The fragmented vacuolar
phenotype of sac mutants could be mimicked by treating wild-type seedlings with
Ptdlns(3,5)P2, corroborating that this PPI is important for vacuole morphology.
Taken together, these results provide evidence that PPIs, together with their
metabolic enzymes SAC2-SAC5, are crucial for vacuolar trafficking and for vacuolar
morphology and function in plants.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Petra
full_name: Marhavá, Petra
id: 44E59624-F248-11E8-B48F-1D18A9856A87
last_name: Marhavá
citation:
ama: Marhavá P. Molecular mechanisms of patterning and subcellular trafficking in
Arabidopsis thaliana. 2014.
apa: Marhavá, P. (2014). Molecular mechanisms of patterning and subcellular trafficking
in Arabidopsis thaliana. Institute of Science and Technology Austria.
chicago: Marhavá, Petra. “Molecular Mechanisms of Patterning and Subcellular Trafficking
in Arabidopsis Thaliana.” Institute of Science and Technology Austria, 2014.
ieee: P. Marhavá, “Molecular mechanisms of patterning and subcellular trafficking
in Arabidopsis thaliana,” Institute of Science and Technology Austria, 2014.
ista: Marhavá P. 2014. Molecular mechanisms of patterning and subcellular trafficking
in Arabidopsis thaliana. Institute of Science and Technology Austria.
mla: Marhavá, Petra. Molecular Mechanisms of Patterning and Subcellular Trafficking
in Arabidopsis Thaliana. Institute of Science and Technology Austria, 2014.
short: P. Marhavá, Molecular Mechanisms of Patterning and Subcellular Trafficking
in Arabidopsis Thaliana, Institute of Science and Technology Austria, 2014.
date_created: 2018-12-11T11:51:49Z
date_published: 2014-12-01T00:00:00Z
date_updated: 2023-09-07T11:39:38Z
day: '01'
degree_awarded: PhD
department:
- _id: JiFr
language:
- iso: eng
month: '12'
oa_version: None
page: '90'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '5805'
status: public
supervisor:
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
title: Molecular mechanisms of patterning and subcellular trafficking in Arabidopsis
thaliana
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2014'
...
---
_id: '1403'
abstract:
- lang: eng
text: A variety of developmental and disease related processes depend on epithelial
cell sheet spreading. In order to gain insight into the biophysical mechanism(s)
underlying the tissue morphogenesis we studied the spreading of an epithelium
during the early development of the zebrafish embryo. In zebrafish epiboly the
enveloping cell layer (EVL), a simple squamous epithelium, spreads over the yolk
cell to completely engulf it at the end of gastrulation. Previous studies have
proposed that an actomyosin ring forming within the yolk syncytial layer (YSL)
acts as purse string that through constriction along its circumference pulls on
the margin of the EVL. Direct biophysical evidence for this hypothesis has however
been missing. The aim of the thesis was to understand how the actomyosin ring
may generate pulling forces onto the EVL and what cellular mechanism(s) may facilitate
the spreading of the epithelium. Using laser ablation to measure cortical tension
within the actomyosin ring we found an anisotropic tension distribution, which
was highest along the circumference of the ring. However the low degree of anisotropy
was incompatible with the actomyosin ring functioning as a purse string only.
Additionally, we observed retrograde cortical flow from vegetal parts of the ring
into the EVL margin. Interpreting the experimental data using a theoretical distribution
that models the tissues as active viscous gels led us to proposen that the actomyosin
ring has a twofold contribution to EVL epiboly. It not only acts as a purse string
through constriction along its circumference, but in addition constriction along
the width of the ring generates pulling forces through friction-resisted cortical
flow. Moreover, when rendering the purse string mechanism unproductive EVL epiboly
proceeded normally indicating that the flow-friction mechanism is sufficient to
drive the process. Aiming to understand what cellular mechanism(s) may facilitate
the spreading of the epithelium we found that tension-oriented EVL cell divisions
limit tissue anisotropy by releasing tension along the division axis and promote
epithelial spreading. Notably, EVL cells undergo ectopic cell fusion in conditions
in which oriented-cell division is impaired or the epithelium is mechanically
challenged. Taken together our study of EVL epiboly suggests a novel mechanism
of force generation for actomyosin rings through friction-resisted cortical flow
and highlights the importance of tension-oriented cell divisions in epithelial
morphogenesis.
acknowledged_ssus:
- _id: SSU
alternative_title:
- IST Austria Thesis
author:
- first_name: Martin
full_name: Behrndt, Martin
id: 3ECECA3A-F248-11E8-B48F-1D18A9856A87
last_name: Behrndt
citation:
ama: Behrndt M. Forces driving epithelial spreading in zebrafish epiboly. 2014.
apa: Behrndt, M. (2014). Forces driving epithelial spreading in zebrafish epiboly.
IST Austria.
chicago: Behrndt, Martin. “Forces Driving Epithelial Spreading in Zebrafish Epiboly.”
IST Austria, 2014.
ieee: M. Behrndt, “Forces driving epithelial spreading in zebrafish epiboly,” IST
Austria, 2014.
ista: Behrndt M. 2014. Forces driving epithelial spreading in zebrafish epiboly.
IST Austria.
mla: Behrndt, Martin. Forces Driving Epithelial Spreading in Zebrafish Epiboly.
IST Austria, 2014.
short: M. Behrndt, Forces Driving Epithelial Spreading in Zebrafish Epiboly, IST
Austria, 2014.
date_created: 2018-12-11T11:51:49Z
date_published: 2014-08-01T00:00:00Z
date_updated: 2023-10-17T12:16:58Z
day: '01'
department:
- _id: CaHe
language:
- iso: eng
month: '08'
oa_version: None
page: '91'
publication_status: published
publisher: IST Austria
publist_id: '5804'
related_material:
record:
- id: '2282'
relation: part_of_dissertation
status: public
- id: '2950'
relation: part_of_dissertation
status: public
- id: '3373'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
title: Forces driving epithelial spreading in zebrafish epiboly
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2014'
...
---
_id: '1404'
abstract:
- lang: eng
text: "The co-evolution of hosts and pathogens is characterized by continuous adaptations
of both parties. Pathogens of social insects need to adapt towards disease defences
at two levels: 1) individual immunity of each colony member consisting of behavioural
defence strategies as well as humoral and cellular immune responses and 2) social
immunity that is collectively performed by all group members comprising behavioural,
physiological and organisational defence strategies.\r\n\r\nTo disentangle the
selection pressure on pathogens by the collective versus individual level of disease
defence in social insects, we performed an evolution experiment using the Argentine
Ant, Linepithema humile, as a host and a mixture of the general insect pathogenic
fungus Metarhizium spp. (6 strains) as a pathogen. We allowed pathogen evolution
over 10 serial host passages to two different evolution host treatments: (1) only
individual host immunity in a single host treatment, and (2) simultaneously acting
individual and social immunity in a social host treatment, in which an exposed
ant was accompanied by two untreated nestmates.\r\n\r\nBefore starting the pathogen
evolution experiment, the 6 Metarhizium spp. strains were characterised concerning
conidiospore size killing rates in singly and socially reared ants, their competitiveness
under coinfecting conditions and their influence on ant behaviour. We analysed
how the ancestral atrain mixture changed in conidiospere size, killing rate and
strain composition dependent on host treatment (single or social hosts) during
10 passages and found that killing rate and conidiospere size of the pathogen
increased under both evolution regimes, but different depending on host treatment.\r\n\r\nTesting
the evolved strain mixtures that evolved under either the single or social host
treatment under both single and social current rearing conditions in a full factorial
design experiment revealed that the additional collective defences in insect societies
add new selection pressure for their coevolving pathogens that compromise their
ability to adapt to its host at the group level. To our knowledge, this is the
first study directly measuring the influence of social immunity on pathogen evolution."
acknowledgement: This work was funded by the DFG and the ERC.
alternative_title:
- IST Austria Thesis
author:
- first_name: Miriam
full_name: Stock, Miriam
id: 42462816-F248-11E8-B48F-1D18A9856A87
last_name: Stock
citation:
ama: Stock M. Evolution of a fungal pathogen towards individual versus social immunity
in ants. 2014.
apa: Stock, M. (2014). Evolution of a fungal pathogen towards individual versus
social immunity in ants. IST Austria.
chicago: Stock, Miriam. “Evolution of a Fungal Pathogen towards Individual versus
Social Immunity in Ants.” IST Austria, 2014.
ieee: M. Stock, “Evolution of a fungal pathogen towards individual versus social
immunity in ants,” IST Austria, 2014.
ista: Stock M. 2014. Evolution of a fungal pathogen towards individual versus social
immunity in ants. IST Austria.
mla: Stock, Miriam. Evolution of a Fungal Pathogen towards Individual versus
Social Immunity in Ants. IST Austria, 2014.
short: M. Stock, Evolution of a Fungal Pathogen towards Individual versus Social
Immunity in Ants, IST Austria, 2014.
date_created: 2018-12-11T11:51:49Z
date_published: 2014-04-01T00:00:00Z
date_updated: 2021-01-12T06:50:30Z
day: '01'
department:
- _id: SyCr
language:
- iso: eng
month: '04'
oa_version: None
page: '101'
publication_status: published
publisher: IST Austria
publist_id: '5803'
status: public
supervisor:
- first_name: Sylvia M
full_name: Cremer, Sylvia M
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
title: Evolution of a fungal pathogen towards individual versus social immunity in
ants
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2014'
...
---
_id: '5411'
abstract:
- lang: eng
text: "Model-based testing is a promising technology for black-box software and
hardware testing, in which test cases are generated automatically from high-level
specifications. Nowadays, systems typically consist of multiple interacting components
and, due to their complexity, testing presents a considerable portion of the effort
and cost in the design process. Exploiting the compositional structure of system
specifications can considerably reduce the effort in model-based testing. Moreover,
inferring properties about the system from testing its individual components allows
the designer to reduce the amount of integration testing.\r\nIn this paper, we
study compositional properties of the IOCO-testing theory. We propose a new approach
to composition and hiding operations, inspired by contract-based design and interface
theories. These operations preserve behaviors that are compatible under composition
and hiding, and prune away incompatible ones. The resulting specification characterizes
the input sequences for which the unit testing of components is sufficient to
infer the correctness of component integration without the need for further tests.
We provide a methodology that uses these results to minimize integration testing
effort, but also to detect potential weaknesses in specifications. While we focus
on asynchronous models and the IOCO conformance relation, the resulting methodology
can be applied to a broader class of systems."
alternative_title:
- IST Austria Technical Report
author:
- first_name: Przemyslaw
full_name: Daca, Przemyslaw
id: 49351290-F248-11E8-B48F-1D18A9856A87
last_name: Daca
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Willibald
full_name: Krenn, Willibald
last_name: Krenn
- first_name: Dejan
full_name: Nickovic, Dejan
id: 41BCEE5C-F248-11E8-B48F-1D18A9856A87
last_name: Nickovic
citation:
ama: Daca P, Henzinger TA, Krenn W, Nickovic D. Compositional Specifications
for IOCO Testing. IST Austria; 2014. doi:10.15479/AT:IST-2014-148-v2-1
apa: Daca, P., Henzinger, T. A., Krenn, W., & Nickovic, D. (2014). Compositional
specifications for IOCO testing. IST Austria. https://doi.org/10.15479/AT:IST-2014-148-v2-1
chicago: Daca, Przemyslaw, Thomas A Henzinger, Willibald Krenn, and Dejan Nickovic.
Compositional Specifications for IOCO Testing. IST Austria, 2014. https://doi.org/10.15479/AT:IST-2014-148-v2-1.
ieee: P. Daca, T. A. Henzinger, W. Krenn, and D. Nickovic, Compositional specifications
for IOCO testing. IST Austria, 2014.
ista: Daca P, Henzinger TA, Krenn W, Nickovic D. 2014. Compositional specifications
for IOCO testing, IST Austria, 20p.
mla: Daca, Przemyslaw, et al. Compositional Specifications for IOCO Testing.
IST Austria, 2014, doi:10.15479/AT:IST-2014-148-v2-1.
short: P. Daca, T.A. Henzinger, W. Krenn, D. Nickovic, Compositional Specifications
for IOCO Testing, IST Austria, 2014.
date_created: 2018-12-12T11:39:11Z
date_published: 2014-01-28T00:00:00Z
date_updated: 2023-02-23T10:31:07Z
day: '28'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.15479/AT:IST-2014-148-v2-1
file:
- access_level: open_access
checksum: 0e03aba625cc334141a3148432aa5760
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:54:21Z
date_updated: 2020-07-14T12:46:46Z
file_id: '5543'
file_name: IST-2014-148-v2+1_main_tr.pdf
file_size: 534732
relation: main_file
file_date_updated: 2020-07-14T12:46:46Z
has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: '20'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '152'
related_material:
record:
- id: '2167'
relation: later_version
status: public
status: public
title: Compositional specifications for IOCO testing
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2014'
...
---
_id: '5412'
abstract:
- lang: eng
text: "We consider Markov decision processes (MDPs) which are a standard model for
probabilistic systems. We focus on qualitative properties for MDPs that can express
that desired behaviors of the system arise almost-surely (with probability 1)
or with positive probability.\r\nWe introduce a new simulation relation to capture
the refinement relation of MDPs with respect to qualitative properties, and present
discrete graph theoretic algorithms with quadratic complexity to compute the simulation
relation.\r\nWe present an automated technique for assume-guarantee style reasoning
for compositional analysis of MDPs with qualitative properties by giving a counter-example
guided abstraction-refinement approach to compute our new simulation relation.
We have implemented our algorithms and show that the compositional analysis leads
to significant improvements. "
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Przemyslaw
full_name: Daca, Przemyslaw
id: 49351290-F248-11E8-B48F-1D18A9856A87
last_name: Daca
- first_name: Martin
full_name: Chmelik, Martin
id: 3624234E-F248-11E8-B48F-1D18A9856A87
last_name: Chmelik
citation:
ama: Chatterjee K, Daca P, Chmelik M. CEGAR for Qualitative Analysis of Probabilistic
Systems. IST Austria; 2014. doi:10.15479/AT:IST-2014-153-v1-1
apa: Chatterjee, K., Daca, P., & Chmelik, M. (2014). CEGAR for qualitative
analysis of probabilistic systems. IST Austria. https://doi.org/10.15479/AT:IST-2014-153-v1-1
chicago: Chatterjee, Krishnendu, Przemyslaw Daca, and Martin Chmelik. CEGAR for
Qualitative Analysis of Probabilistic Systems. IST Austria, 2014. https://doi.org/10.15479/AT:IST-2014-153-v1-1.
ieee: K. Chatterjee, P. Daca, and M. Chmelik, CEGAR for qualitative analysis
of probabilistic systems. IST Austria, 2014.
ista: Chatterjee K, Daca P, Chmelik M. 2014. CEGAR for qualitative analysis of probabilistic
systems, IST Austria, 31p.
mla: Chatterjee, Krishnendu, et al. CEGAR for Qualitative Analysis of Probabilistic
Systems. IST Austria, 2014, doi:10.15479/AT:IST-2014-153-v1-1.
short: K. Chatterjee, P. Daca, M. Chmelik, CEGAR for Qualitative Analysis of Probabilistic
Systems, IST Austria, 2014.
date_created: 2018-12-12T11:39:11Z
date_published: 2014-01-29T00:00:00Z
date_updated: 2023-02-23T12:25:18Z
day: '29'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2014-153-v1-1
file:
- access_level: open_access
checksum: 4d6cda4bebed970926403ad6ad8c745f
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:39Z
date_updated: 2020-07-14T12:46:47Z
file_id: '5500'
file_name: IST-2014-153-v1+1_main.pdf
file_size: 423322
relation: main_file
file_date_updated: 2020-07-14T12:46:47Z
has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: '31'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '153'
related_material:
record:
- id: '2063'
relation: later_version
status: public
- id: '5413'
relation: later_version
status: public
- id: '5414'
relation: later_version
status: public
status: public
title: CEGAR for qualitative analysis of probabilistic systems
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2014'
...