---
_id: '6519'
abstract:
- lang: eng
text: 'Graph games with omega-regular winning conditions provide a mathematical
framework to analyze a wide range of problems in the analysis of reactive systems
and programs (such as the synthesis of reactive systems, program repair, and the
verification of branching time properties). Parity conditions are canonical forms
to specify omega-regular winning conditions. Graph games with parity conditions
are equivalent to mu-calculus model checking, and thus a very important algorithmic
problem. Symbolic algorithms are of great significance because they provide scalable
algorithms for the analysis of large finite-state systems, as well as algorithms
for the analysis of infinite-state systems with finite quotient. A set-based symbolic
algorithm uses the basic set operations and the one-step predecessor operators.
We consider graph games with n vertices and parity conditions with c priorities
(equivalently, a mu-calculus formula with c alternations of least and greatest
fixed points). While many explicit algorithms exist for graph games with parity
conditions, for set-based symbolic algorithms there are only two algorithms (notice
that we use space to refer to the number of sets stored by a symbolic algorithm):
(a) the basic algorithm that requires O(n^c) symbolic operations and linear space;
and (b) an improved algorithm that requires O(n^{c/2+1}) symbolic operations but
also O(n^{c/2+1}) space (i.e., exponential space). In this work we present two
set-based symbolic algorithms for parity games: (a) our first algorithm requires
O(n^{c/2+1}) symbolic operations and only requires linear space; and (b) developing
on our first algorithm, we present an algorithm that requires O(n^{c/3+1}) symbolic
operations and only linear space. We also present the first linear space set-based
symbolic algorithm for parity games that requires at most a sub-exponential number
of symbolic operations. '
article_number: '18'
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Wolfgang
full_name: Dvorák, Wolfgang
last_name: Dvorák
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Veronika
full_name: Loitzenbauer, Veronika
last_name: Loitzenbauer
citation:
ama: 'Chatterjee K, Dvorák W, Henzinger MH, Loitzenbauer V. Improved set-based symbolic
algorithms for parity games. In: Vol 82. Schloss Dagstuhl -Leibniz-Zentrum fuer
Informatik; 2017. doi:10.4230/LIPICS.CSL.2017.18'
apa: 'Chatterjee, K., Dvorák, W., Henzinger, M. H., & Loitzenbauer, V. (2017).
Improved set-based symbolic algorithms for parity games (Vol. 82). Presented at
the CSL: Conference on Computer Science Logic, Stockholm, Sweden: Schloss Dagstuhl
-Leibniz-Zentrum fuer Informatik. https://doi.org/10.4230/LIPICS.CSL.2017.18'
chicago: Chatterjee, Krishnendu, Wolfgang Dvorák, Monika H Henzinger, and Veronika
Loitzenbauer. “Improved Set-Based Symbolic Algorithms for Parity Games,” Vol.
82. Schloss Dagstuhl -Leibniz-Zentrum fuer Informatik, 2017. https://doi.org/10.4230/LIPICS.CSL.2017.18.
ieee: 'K. Chatterjee, W. Dvorák, M. H. Henzinger, and V. Loitzenbauer, “Improved
set-based symbolic algorithms for parity games,” presented at the CSL: Conference
on Computer Science Logic, Stockholm, Sweden, 2017, vol. 82.'
ista: 'Chatterjee K, Dvorák W, Henzinger MH, Loitzenbauer V. 2017. Improved set-based
symbolic algorithms for parity games. CSL: Conference on Computer Science Logic
vol. 82, 18.'
mla: Chatterjee, Krishnendu, et al. Improved Set-Based Symbolic Algorithms for
Parity Games. Vol. 82, 18, Schloss Dagstuhl -Leibniz-Zentrum fuer Informatik,
2017, doi:10.4230/LIPICS.CSL.2017.18.
short: K. Chatterjee, W. Dvorák, M.H. Henzinger, V. Loitzenbauer, in:, Schloss Dagstuhl
-Leibniz-Zentrum fuer Informatik, 2017.
conference:
end_date: 2017-08-24
location: Stockholm, Sweden
name: 'CSL: Conference on Computer Science Logic'
start_date: 2017-08-20
date_created: 2019-06-04T12:42:43Z
date_published: 2017-08-01T00:00:00Z
date_updated: 2025-06-02T08:53:46Z
day: '01'
ddc:
- '004'
department:
- _id: KrCh
doi: 10.4230/LIPICS.CSL.2017.18
ec_funded: 1
file:
- access_level: open_access
checksum: 7c2c9d09970af79026d7e37d9b632ef8
content_type: application/pdf
creator: kschuh
date_created: 2019-06-04T12:56:52Z
date_updated: 2020-07-14T12:47:33Z
file_id: '6520'
file_name: 2017_LIPIcs-Chatterjee.pdf
file_size: 710185
relation: main_file
file_date_updated: 2020-07-14T12:47:33Z
has_accepted_license: '1'
intvolume: ' 82'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/3.0/
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
grant_number: ICT15-003
name: Efficient Algorithms for Computer Aided Verification
publication_status: published
publisher: Schloss Dagstuhl -Leibniz-Zentrum fuer Informatik
quality_controlled: '1'
scopus_import: '1'
status: public
title: Improved set-based symbolic algorithms for parity games
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/3.0/legalcode
name: Creative Commons Attribution 3.0 Unported (CC BY 3.0)
short: CC BY (3.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 82
year: '2017'
...
---
_id: '652'
abstract:
- lang: eng
text: 'We present an approach that enables robots to self-organize their sensorimotor
behavior from scratch without providing specific information about neither the
robot nor its environment. This is achieved by a simple neural control law that
increases the consistency between external sensor dynamics and internal neural
dynamics of the utterly simple controller. In this way, the embodiment and the
agent-environment coupling are the only source of individual development. We show
how an anthropomorphic tendon driven arm-shoulder system develops different behaviors
depending on that coupling. For instance: Given a bottle half-filled with water,
the arm starts to shake it, driven by the physical response of the water. When
attaching a brush, the arm can be manipulated into wiping a table, and when connected
to a revolvable wheel it finds out how to rotate it. Thus, the robot may be said
to discover the affordances of the world. When allowing two (simulated) humanoid
robots to interact physically, they engage into a joint behavior development leading
to, for instance, spontaneous cooperation. More social effects are observed if
the robots can visually perceive each other. Although, as an observer, it is tempting
to attribute an apparent intentionality, there is nothing of the kind put in.
As a conclusion, we argue that emergent behavior may be much less rooted in explicit
intentions, internal motivations, or specific reward systems than is commonly
believed.'
article_number: '7846789'
author:
- first_name: Ralf
full_name: Der, Ralf
last_name: Der
- first_name: Georg S
full_name: Martius, Georg S
id: 3A276B68-F248-11E8-B48F-1D18A9856A87
last_name: Martius
citation:
ama: 'Der R, Martius GS. Dynamical self consistency leads to behavioral development
and emergent social interactions in robots. In: IEEE; 2017. doi:10.1109/DEVLRN.2016.7846789'
apa: 'Der, R., & Martius, G. S. (2017). Dynamical self consistency leads to
behavioral development and emergent social interactions in robots. Presented at
the ICDL EpiRob: International Conference on Development and Learning and Epigenetic
Robotics , Cergy-Pontoise, France: IEEE. https://doi.org/10.1109/DEVLRN.2016.7846789'
chicago: Der, Ralf, and Georg S Martius. “Dynamical Self Consistency Leads to Behavioral
Development and Emergent Social Interactions in Robots.” IEEE, 2017. https://doi.org/10.1109/DEVLRN.2016.7846789.
ieee: 'R. Der and G. S. Martius, “Dynamical self consistency leads to behavioral
development and emergent social interactions in robots,” presented at the ICDL
EpiRob: International Conference on Development and Learning and Epigenetic Robotics
, Cergy-Pontoise, France, 2017.'
ista: 'Der R, Martius GS. 2017. Dynamical self consistency leads to behavioral development
and emergent social interactions in robots. ICDL EpiRob: International Conference
on Development and Learning and Epigenetic Robotics , 7846789.'
mla: Der, Ralf, and Georg S. Martius. Dynamical Self Consistency Leads to Behavioral
Development and Emergent Social Interactions in Robots. 7846789, IEEE, 2017,
doi:10.1109/DEVLRN.2016.7846789.
short: R. Der, G.S. Martius, in:, IEEE, 2017.
conference:
end_date: 2016-09-22
location: Cergy-Pontoise, France
name: 'ICDL EpiRob: International Conference on Development and Learning and Epigenetic
Robotics '
start_date: 2016-09-19
date_created: 2018-12-11T11:47:43Z
date_published: 2017-02-07T00:00:00Z
date_updated: 2021-01-12T08:07:51Z
day: '07'
department:
- _id: ChLa
- _id: GaTk
doi: 10.1109/DEVLRN.2016.7846789
language:
- iso: eng
month: '02'
oa_version: None
publication_identifier:
isbn:
- 978-150905069-7
publication_status: published
publisher: IEEE
publist_id: '7100'
quality_controlled: '1'
scopus_import: 1
status: public
title: Dynamical self consistency leads to behavioral development and emergent social
interactions in robots
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2017'
...
---
_id: '6526'
abstract:
- lang: eng
text: 'This paper studies the complexity of estimating Rényi divergences of discrete
distributions: p observed from samples and the baseline distribution q known a
priori. Extending the results of Acharya et al. (SODA''15) on estimating Rényi
entropy, we present improved estimation techniques together with upper and lower
bounds on the sample complexity. We show that, contrarily to estimating Rényi
entropy where a sublinear (in the alphabet size) number of samples suffices, the
sample complexity is heavily dependent on events occurring unlikely in q, and
is unbounded in general (no matter what an estimation technique is used). For
any divergence of integer order bigger than 1, we provide upper and lower bounds
on the number of samples dependent on probabilities of p and q (the lower bounds
hold for non-integer orders as well). We conclude that the worst-case sample complexity
is polynomial in the alphabet size if and only if the probabilities of q are non-negligible.
This gives theoretical insights into heuristics used in the applied literature
to handle numerical instability, which occurs for small probabilities of q. Our
result shows that they should be handled with care not only because of numerical
issues, but also because of a blow up in the sample complexity.'
article_number: '8006529'
arxiv: 1
author:
- first_name: Maciej
full_name: Skórski, Maciej
id: EC09FA6A-02D0-11E9-8223-86B7C91467DD
last_name: Skórski
citation:
ama: 'Skórski M. On the complexity of estimating Rènyi divergences. In: 2017
IEEE International Symposium on Information Theory (ISIT). IEEE; 2017. doi:10.1109/isit.2017.8006529'
apa: 'Skórski, M. (2017). On the complexity of estimating Rènyi divergences. In
2017 IEEE International Symposium on Information Theory (ISIT). Aachen,
Germany: IEEE. https://doi.org/10.1109/isit.2017.8006529'
chicago: Skórski, Maciej. “On the Complexity of Estimating Rènyi Divergences.” In
2017 IEEE International Symposium on Information Theory (ISIT). IEEE, 2017.
https://doi.org/10.1109/isit.2017.8006529.
ieee: M. Skórski, “On the complexity of estimating Rènyi divergences,” in 2017
IEEE International Symposium on Information Theory (ISIT), Aachen, Germany,
2017.
ista: 'Skórski M. 2017. On the complexity of estimating Rènyi divergences. 2017
IEEE International Symposium on Information Theory (ISIT). ISIT: International
Symposium on Information Theory, 8006529.'
mla: Skórski, Maciej. “On the Complexity of Estimating Rènyi Divergences.” 2017
IEEE International Symposium on Information Theory (ISIT), 8006529, IEEE,
2017, doi:10.1109/isit.2017.8006529.
short: M. Skórski, in:, 2017 IEEE International Symposium on Information Theory
(ISIT), IEEE, 2017.
conference:
end_date: 2017-06-30
location: Aachen, Germany
name: 'ISIT: International Symposium on Information Theory'
start_date: 2017-06-25
date_created: 2019-06-06T12:53:09Z
date_published: 2017-08-09T00:00:00Z
date_updated: 2021-01-12T08:07:53Z
day: '09'
department:
- _id: KrPi
doi: 10.1109/isit.2017.8006529
ec_funded: 1
external_id:
arxiv:
- '1702.01666'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1702.01666
month: '08'
oa: 1
oa_version: Preprint
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '682815'
name: Teaching Old Crypto New Tricks
publication: 2017 IEEE International Symposium on Information Theory (ISIT)
publication_identifier:
isbn:
- '9781509040964'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: 1
status: public
title: On the complexity of estimating Rènyi divergences
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2017'
...
---
_id: '6527'
abstract:
- lang: eng
text: "A memory-hard function (MHF) ƒn with parameter n can be computed in sequential
time and space n. Simultaneously, a high amortized parallel area-time complexity
(aAT) is incurred per evaluation. In practice, MHFs are used to limit the rate
at which an adversary (using a custom computational device) can evaluate a security
sensitive function that still occasionally needs to be evaluated by honest users
(using an off-the-shelf general purpose device). The most prevalent examples of
such sensitive functions are Key Derivation Functions (KDFs) and password hashing
algorithms where rate limits help mitigate off-line dictionary attacks. As the
honest users' inputs to these functions are often (low-entropy) passwords special
attention is given to a class of side-channel resistant MHFs called iMHFs.\r\n\r\nEssentially
all iMHFs can be viewed as some mode of operation (making n calls to some round
function) given by a directed acyclic graph (DAG) with very low indegree. Recently,
a combinatorial property of a DAG has been identified (called \"depth-robustness\")
which results in good provable security for an iMHF based on that DAG. Depth-robust
DAGs have also proven useful in other cryptographic applications. Unfortunately,
up till now, all known very depth-robust DAGs are impractically complicated and
little is known about their exact (i.e. non-asymptotic) depth-robustness both
in theory and in practice.\r\n\r\nIn this work we build and analyze (both formally
and empirically) several exceedingly simple and efficient to navigate practical
DAGs for use in iMHFs and other applications. For each DAG we:\r\n*Prove that
their depth-robustness is asymptotically maximal.\r\n*Prove bounds of at least
3 orders of magnitude better on their exact depth-robustness compared to known
bounds for other practical iMHF.\r\n*Implement and empirically evaluate their
depth-robustness and aAT against a variety of state-of-the art (and several new)
depth-reduction and low aAT attacks. \r\nWe find that, against all attacks, the
new DAGs perform significantly better in practice than Argon2i, the most widely
deployed iMHF in practice.\r\n\r\nAlong the way we also improve the best known
empirical attacks on the aAT of Argon2i by implementing and testing several heuristic
versions of a (hitherto purely theoretical) depth-reduction attack. Finally, we
demonstrate practicality of our constructions by modifying the Argon2i code base
to use one of the new high aAT DAGs. Experimental benchmarks on a standard off-the-shelf
CPU show that the new modifications do not adversely affect the impressive throughput
of Argon2i (despite seemingly enjoying significantly higher aAT).\r\n"
author:
- first_name: Joel F
full_name: Alwen, Joel F
id: 2A8DFA8C-F248-11E8-B48F-1D18A9856A87
last_name: Alwen
- first_name: Jeremiah
full_name: Blocki, Jeremiah
last_name: Blocki
- first_name: Ben
full_name: Harsha, Ben
last_name: Harsha
citation:
ama: 'Alwen JF, Blocki J, Harsha B. Practical graphs for optimal side-channel resistant
memory-hard functions. In: Proceedings of the 2017 ACM SIGSAC Conference on
Computer and Communications Security. ACM Press; 2017:1001-1017. doi:10.1145/3133956.3134031'
apa: 'Alwen, J. F., Blocki, J., & Harsha, B. (2017). Practical graphs for optimal
side-channel resistant memory-hard functions. In Proceedings of the 2017 ACM
SIGSAC Conference on Computer and Communications Security (pp. 1001–1017).
Dallas, TX, USA: ACM Press. https://doi.org/10.1145/3133956.3134031'
chicago: Alwen, Joel F, Jeremiah Blocki, and Ben Harsha. “Practical Graphs for Optimal
Side-Channel Resistant Memory-Hard Functions.” In Proceedings of the 2017 ACM
SIGSAC Conference on Computer and Communications Security, 1001–17. ACM Press,
2017. https://doi.org/10.1145/3133956.3134031.
ieee: J. F. Alwen, J. Blocki, and B. Harsha, “Practical graphs for optimal side-channel
resistant memory-hard functions,” in Proceedings of the 2017 ACM SIGSAC Conference
on Computer and Communications Security, Dallas, TX, USA, 2017, pp. 1001–1017.
ista: 'Alwen JF, Blocki J, Harsha B. 2017. Practical graphs for optimal side-channel
resistant memory-hard functions. Proceedings of the 2017 ACM SIGSAC Conference
on Computer and Communications Security. CCS: Conference on Computer and Communications
Security, 1001–1017.'
mla: Alwen, Joel F., et al. “Practical Graphs for Optimal Side-Channel Resistant
Memory-Hard Functions.” Proceedings of the 2017 ACM SIGSAC Conference on Computer
and Communications Security, ACM Press, 2017, pp. 1001–17, doi:10.1145/3133956.3134031.
short: J.F. Alwen, J. Blocki, B. Harsha, in:, Proceedings of the 2017 ACM SIGSAC
Conference on Computer and Communications Security, ACM Press, 2017, pp. 1001–1017.
conference:
end_date: 2017-11-03
location: Dallas, TX, USA
name: 'CCS: Conference on Computer and Communications Security'
start_date: 2017-10-30
date_created: 2019-06-06T13:21:29Z
date_published: 2017-10-30T00:00:00Z
date_updated: 2021-01-12T08:07:53Z
day: '30'
department:
- _id: KrPi
doi: 10.1145/3133956.3134031
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprint.iacr.org/2017/443
month: '10'
oa: 1
oa_version: Submitted Version
page: 1001-1017
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '682815'
name: Teaching Old Crypto New Tricks
publication: Proceedings of the 2017 ACM SIGSAC Conference on Computer and Communications
Security
publication_identifier:
isbn:
- '9781450349468'
publication_status: published
publisher: ACM Press
quality_controlled: '1'
scopus_import: 1
status: public
title: Practical graphs for optimal side-channel resistant memory-hard functions
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2017'
...
---
_id: '653'
abstract:
- lang: eng
text: The extent of heterogeneity among driver gene mutations present in naturally
occurring metastases - that is, treatment-naive metastatic disease - is largely
unknown. To address this issue, we carried out 60× whole-genome sequencing of
26 metastases from four patients with pancreatic cancer. We found that identical
mutations in known driver genes were present in every metastatic lesion for each
patient studied. Passenger gene mutations, which do not have known or predicted
functional consequences, accounted for all intratumoral heterogeneity. Even with
respect to these passenger mutations, our analysis suggests that the genetic similarity
among the founding cells of metastases was higher than that expected for any two
cells randomly taken from a normal tissue. The uniformity of known driver gene
mutations among metastases in the same patient has critical and encouraging implications
for the success of future targeted therapies in advanced-stage disease.
acknowledgement: 'We thank the Memorial Sloan Kettering Cancer Center Molecular Cytology
core facility for immunohistochemistry staining. This work was supported by Office
of Naval Research grant N00014-16-1-2914, the Bill and Melinda Gates Foundation
(OPP1148627), and a gift from B. Wu and E. Larson (M.A.N.), National Institutes
of Health grants CA179991 (C.A.I.-D. and I.B.), F31 CA180682 (A.P.M.-M.), CA43460
(B.V.), and P50 CA62924, the Monastra Foundation, the Virginia and D.K. Ludwig Fund
for Cancer Research, the Lustgarten Foundation for Pancreatic Cancer Research, the
Sol Goldman Center for Pancreatic Cancer Research, the Sol Goldman Sequencing Center,
ERC Start grant 279307: Graph Games (J.G.R., D.K., and C.K.), Austrian Science Fund
(FWF) grant P23499-N23 (J.G.R., D.K., and C.K.), and FWF NFN grant S11407-N23 RiSE/SHiNE
(J.G.R., D.K., and C.K.).'
article_processing_charge: No
article_type: original
author:
- first_name: Alvin
full_name: Makohon Moore, Alvin
last_name: Makohon Moore
- first_name: Ming
full_name: Zhang, Ming
last_name: Zhang
- first_name: Johannes
full_name: Reiter, Johannes
id: 4A918E98-F248-11E8-B48F-1D18A9856A87
last_name: Reiter
orcid: 0000-0002-0170-7353
- first_name: Ivana
full_name: Božić, Ivana
last_name: Božić
- first_name: Benjamin
full_name: Allen, Benjamin
last_name: Allen
- first_name: Deepanjan
full_name: Kundu, Deepanjan
id: 1d4c0f4f-e8a3-11ec-a351-e36772758c45
last_name: Kundu
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Fay
full_name: Wong, Fay
last_name: Wong
- first_name: Yuchen
full_name: Jiao, Yuchen
last_name: Jiao
- first_name: Zachary
full_name: Kohutek, Zachary
last_name: Kohutek
- first_name: Jungeui
full_name: Hong, Jungeui
last_name: Hong
- first_name: Marc
full_name: Attiyeh, Marc
last_name: Attiyeh
- first_name: Breanna
full_name: Javier, Breanna
last_name: Javier
- first_name: Laura
full_name: Wood, Laura
last_name: Wood
- first_name: Ralph
full_name: Hruban, Ralph
last_name: Hruban
- first_name: Martin
full_name: Nowak, Martin
last_name: Nowak
- first_name: Nickolas
full_name: Papadopoulos, Nickolas
last_name: Papadopoulos
- first_name: Kenneth
full_name: Kinzler, Kenneth
last_name: Kinzler
- first_name: Bert
full_name: Vogelstein, Bert
last_name: Vogelstein
- first_name: Christine
full_name: Iacobuzio Donahue, Christine
last_name: Iacobuzio Donahue
citation:
ama: Makohon Moore A, Zhang M, Reiter J, et al. Limited heterogeneity of known driver
gene mutations among the metastases of individual patients with pancreatic cancer.
Nature Genetics. 2017;49(3):358-366. doi:10.1038/ng.3764
apa: Makohon Moore, A., Zhang, M., Reiter, J., Božić, I., Allen, B., Kundu, D.,
… Iacobuzio Donahue, C. (2017). Limited heterogeneity of known driver gene mutations
among the metastases of individual patients with pancreatic cancer. Nature
Genetics. Nature Publishing Group. https://doi.org/10.1038/ng.3764
chicago: Makohon Moore, Alvin, Ming Zhang, Johannes Reiter, Ivana Božić, Benjamin
Allen, Deepanjan Kundu, Krishnendu Chatterjee, et al. “Limited Heterogeneity of
Known Driver Gene Mutations among the Metastases of Individual Patients with Pancreatic
Cancer.” Nature Genetics. Nature Publishing Group, 2017. https://doi.org/10.1038/ng.3764.
ieee: A. Makohon Moore et al., “Limited heterogeneity of known driver gene
mutations among the metastases of individual patients with pancreatic cancer,”
Nature Genetics, vol. 49, no. 3. Nature Publishing Group, pp. 358–366,
2017.
ista: Makohon Moore A, Zhang M, Reiter J, Božić I, Allen B, Kundu D, Chatterjee
K, Wong F, Jiao Y, Kohutek Z, Hong J, Attiyeh M, Javier B, Wood L, Hruban R, Nowak
M, Papadopoulos N, Kinzler K, Vogelstein B, Iacobuzio Donahue C. 2017. Limited
heterogeneity of known driver gene mutations among the metastases of individual
patients with pancreatic cancer. Nature Genetics. 49(3), 358–366.
mla: Makohon Moore, Alvin, et al. “Limited Heterogeneity of Known Driver Gene Mutations
among the Metastases of Individual Patients with Pancreatic Cancer.” Nature
Genetics, vol. 49, no. 3, Nature Publishing Group, 2017, pp. 358–66, doi:10.1038/ng.3764.
short: A. Makohon Moore, M. Zhang, J. Reiter, I. Božić, B. Allen, D. Kundu, K. Chatterjee,
F. Wong, Y. Jiao, Z. Kohutek, J. Hong, M. Attiyeh, B. Javier, L. Wood, R. Hruban,
M. Nowak, N. Papadopoulos, K. Kinzler, B. Vogelstein, C. Iacobuzio Donahue, Nature
Genetics 49 (2017) 358–366.
date_created: 2018-12-11T11:47:43Z
date_published: 2017-03-01T00:00:00Z
date_updated: 2022-06-10T09:55:08Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1038/ng.3764
ec_funded: 1
external_id:
pmid:
- '28092682'
file:
- access_level: open_access
checksum: e442dc3b7420a36ec805e9bb45cc1a2e
content_type: application/pdf
creator: dernst
date_created: 2019-11-19T08:13:50Z
date_updated: 2020-07-14T12:47:33Z
file_id: '7050'
file_name: 2017_NatureGenetics_Makohon.pdf
file_size: 908099
relation: main_file
file_date_updated: 2020-07-14T12:47:33Z
has_accepted_license: '1'
intvolume: ' 49'
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Submitted Version
page: 358 - 366
pmid: 1
project:
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
publication: Nature Genetics
publication_identifier:
issn:
- '10614036'
publication_status: published
publisher: Nature Publishing Group
publist_id: '7092'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Limited heterogeneity of known driver gene mutations among the metastases of
individual patients with pancreatic cancer
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 49
year: '2017'
...
---
_id: '654'
abstract:
- lang: eng
text: In November 2016, developmental biologists, synthetic biologists and engineers
gathered in Paris for a meeting called ‘Engineering the embryo’. The participants
shared an interest in exploring how synthetic systems can reveal new principles
of embryonic development, and how the in vitro manipulation and modeling of development
using stem cells can be used to integrate ideas and expertise from physics, developmental
biology and tissue engineering. As we review here, the conference pinpointed some
of the challenges arising at the intersection of these fields, along with great
enthusiasm for finding new approaches and collaborations.
author:
- first_name: Anna
full_name: Kicheva, Anna
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
- first_name: Nicolas
full_name: Rivron, Nicolas
last_name: Rivron
citation:
ama: Kicheva A, Rivron N. Creating to understand – developmental biology meets engineering
in Paris. Development. 2017;144(5):733-736. doi:10.1242/dev.144915
apa: Kicheva, A., & Rivron, N. (2017). Creating to understand – developmental
biology meets engineering in Paris. Development. Company of Biologists.
https://doi.org/10.1242/dev.144915
chicago: Kicheva, Anna, and Nicolas Rivron. “Creating to Understand – Developmental
Biology Meets Engineering in Paris.” Development. Company of Biologists,
2017. https://doi.org/10.1242/dev.144915.
ieee: A. Kicheva and N. Rivron, “Creating to understand – developmental biology
meets engineering in Paris,” Development, vol. 144, no. 5. Company of Biologists,
pp. 733–736, 2017.
ista: Kicheva A, Rivron N. 2017. Creating to understand – developmental biology
meets engineering in Paris. Development. 144(5), 733–736.
mla: Kicheva, Anna, and Nicolas Rivron. “Creating to Understand – Developmental
Biology Meets Engineering in Paris.” Development, vol. 144, no. 5, Company
of Biologists, 2017, pp. 733–36, doi:10.1242/dev.144915.
short: A. Kicheva, N. Rivron, Development 144 (2017) 733–736.
date_created: 2018-12-11T11:47:44Z
date_published: 2017-03-01T00:00:00Z
date_updated: 2021-01-12T08:07:54Z
day: '01'
ddc:
- '571'
department:
- _id: AnKi
doi: 10.1242/dev.144915
ec_funded: 1
file:
- access_level: open_access
checksum: eef22a0f42a55b232cb2d1188a2322cb
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:20Z
date_updated: 2020-07-14T12:47:33Z
file_id: '5139'
file_name: IST-2018-987-v1+1_2017_KichevaRivron__Creating_to.pdf
file_size: 228206
relation: main_file
file_date_updated: 2020-07-14T12:47:33Z
has_accepted_license: '1'
intvolume: ' 144'
issue: '5'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Submitted Version
page: 733 - 736
project:
- _id: B6FC0238-B512-11E9-945C-1524E6697425
call_identifier: H2020
grant_number: '680037'
name: Coordination of Patterning And Growth In the Spinal Cord
publication: Development
publication_identifier:
issn:
- '09501991'
publication_status: published
publisher: Company of Biologists
publist_id: '7089'
pubrep_id: '987'
quality_controlled: '1'
scopus_import: 1
status: public
title: Creating to understand – developmental biology meets engineering in Paris
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 144
year: '2017'
...
---
_id: '655'
abstract:
- lang: eng
text: 'The bacterial flagellum is a self-assembling nanomachine. The external flagellar
filament, several times longer than a bacterial cell body, is made of a few tens
of thousands subunits of a single protein: flagellin. A fundamental problem concerns
the molecular mechanism of how the flagellum grows outside the cell, where no
discernible energy source is available. Here, we monitored the dynamic assembly
of individual flagella using in situ labelling and real-time immunostaining of
elongating flagellar filaments. We report that the rate of flagellum growth, initially
~1,700 amino acids per second, decreases with length and that the previously proposed
chain mechanism does not contribute to the filament elongation dynamics. Inhibition
of the proton motive force-dependent export apparatus revealed a major contribution
of substrate injection in driving filament elongation. The combination of experimental
and mathematical evidence demonstrates that a simple, injection-diffusion mechanism
controls bacterial flagella growth outside the cell.'
article_number: e23136
author:
- first_name: Thibaud
full_name: Renault, Thibaud
last_name: Renault
- first_name: Anthony
full_name: Abraham, Anthony
last_name: Abraham
- first_name: Tobias
full_name: Bergmiller, Tobias
id: 2C471CFA-F248-11E8-B48F-1D18A9856A87
last_name: Bergmiller
orcid: 0000-0001-5396-4346
- first_name: Guillaume
full_name: Paradis, Guillaume
last_name: Paradis
- first_name: Simon
full_name: Rainville, Simon
last_name: Rainville
- first_name: Emmanuelle
full_name: Charpentier, Emmanuelle
last_name: Charpentier
- first_name: Calin C
full_name: Guet, Calin C
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
- first_name: Yuhai
full_name: Tu, Yuhai
last_name: Tu
- first_name: Keiichi
full_name: Namba, Keiichi
last_name: Namba
- first_name: James
full_name: Keener, James
last_name: Keener
- first_name: Tohru
full_name: Minamino, Tohru
last_name: Minamino
- first_name: Marc
full_name: Erhardt, Marc
last_name: Erhardt
citation:
ama: Renault T, Abraham A, Bergmiller T, et al. Bacterial flagella grow through
an injection diffusion mechanism. eLife. 2017;6. doi:10.7554/eLife.23136
apa: Renault, T., Abraham, A., Bergmiller, T., Paradis, G., Rainville, S., Charpentier,
E., … Erhardt, M. (2017). Bacterial flagella grow through an injection diffusion
mechanism. ELife. eLife Sciences Publications. https://doi.org/10.7554/eLife.23136
chicago: Renault, Thibaud, Anthony Abraham, Tobias Bergmiller, Guillaume Paradis,
Simon Rainville, Emmanuelle Charpentier, Calin C Guet, et al. “Bacterial Flagella
Grow through an Injection Diffusion Mechanism.” ELife. eLife Sciences Publications,
2017. https://doi.org/10.7554/eLife.23136.
ieee: T. Renault et al., “Bacterial flagella grow through an injection diffusion
mechanism,” eLife, vol. 6. eLife Sciences Publications, 2017.
ista: Renault T, Abraham A, Bergmiller T, Paradis G, Rainville S, Charpentier E,
Guet CC, Tu Y, Namba K, Keener J, Minamino T, Erhardt M. 2017. Bacterial flagella
grow through an injection diffusion mechanism. eLife. 6, e23136.
mla: Renault, Thibaud, et al. “Bacterial Flagella Grow through an Injection Diffusion
Mechanism.” ELife, vol. 6, e23136, eLife Sciences Publications, 2017, doi:10.7554/eLife.23136.
short: T. Renault, A. Abraham, T. Bergmiller, G. Paradis, S. Rainville, E. Charpentier,
C.C. Guet, Y. Tu, K. Namba, J. Keener, T. Minamino, M. Erhardt, ELife 6 (2017).
date_created: 2018-12-11T11:47:44Z
date_published: 2017-03-06T00:00:00Z
date_updated: 2021-01-12T08:07:55Z
day: '06'
ddc:
- '579'
department:
- _id: CaGu
doi: 10.7554/eLife.23136
file:
- access_level: open_access
checksum: 39e1c3e82ddac83a30422fa72fa1a383
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:53Z
date_updated: 2020-07-14T12:47:33Z
file_id: '4716'
file_name: IST-2017-904-v1+1_elife-23136-v2.pdf
file_size: 5520359
relation: main_file
- access_level: open_access
checksum: a6d542253028f52e00aa29739ddffe8f
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:54Z
date_updated: 2020-07-14T12:47:33Z
file_id: '4717'
file_name: IST-2017-904-v1+2_elife-23136-figures-v2.pdf
file_size: 11242920
relation: main_file
file_date_updated: 2020-07-14T12:47:33Z
has_accepted_license: '1'
intvolume: ' 6'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: eLife
publication_identifier:
issn:
- 2050084X
publication_status: published
publisher: eLife Sciences Publications
publist_id: '7082'
pubrep_id: '904'
quality_controlled: '1'
scopus_import: 1
status: public
title: Bacterial flagella grow through an injection diffusion mechanism
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2017'
...
---
_id: '656'
abstract:
- lang: eng
text: Human neurons transplanted into a mouse model for Alzheimer’s disease show
human-specific vulnerability to β-amyloid plaques and may help to identify new
therapeutic targets.
article_number: eaam9867
author:
- first_name: Gaia
full_name: Novarino, Gaia
id: 3E57A680-F248-11E8-B48F-1D18A9856A87
last_name: Novarino
orcid: 0000-0002-7673-7178
citation:
ama: Novarino G. Modeling Alzheimer’s disease in mice with human neurons. Science
Translational Medicine. 2017;9(381). doi:10.1126/scitranslmed.aam9867
apa: Novarino, G. (2017). Modeling Alzheimer’s disease in mice with human neurons.
Science Translational Medicine. American Association for the Advancement
of Science. https://doi.org/10.1126/scitranslmed.aam9867
chicago: Novarino, Gaia. “Modeling Alzheimer’s Disease in Mice with Human Neurons.”
Science Translational Medicine. American Association for the Advancement
of Science, 2017. https://doi.org/10.1126/scitranslmed.aam9867.
ieee: G. Novarino, “Modeling Alzheimer’s disease in mice with human neurons,” Science
Translational Medicine, vol. 9, no. 381. American Association for the Advancement
of Science, 2017.
ista: Novarino G. 2017. Modeling Alzheimer’s disease in mice with human neurons.
Science Translational Medicine. 9(381), eaam9867.
mla: Novarino, Gaia. “Modeling Alzheimer’s Disease in Mice with Human Neurons.”
Science Translational Medicine, vol. 9, no. 381, eaam9867, American Association
for the Advancement of Science, 2017, doi:10.1126/scitranslmed.aam9867.
short: G. Novarino, Science Translational Medicine 9 (2017).
date_created: 2018-12-11T11:47:45Z
date_published: 2017-03-15T00:00:00Z
date_updated: 2021-01-12T08:07:59Z
day: '15'
department:
- _id: GaNo
doi: 10.1126/scitranslmed.aam9867
intvolume: ' 9'
issue: '381'
language:
- iso: eng
month: '03'
oa_version: None
publication: Science Translational Medicine
publication_identifier:
issn:
- '19466234'
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '7079'
quality_controlled: '1'
scopus_import: 1
status: public
title: Modeling Alzheimer's disease in mice with human neurons
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2017'
...
---
_id: '657'
abstract:
- lang: eng
text: Plant organs are typically organized into three main tissue layers. The middle
ground tissue layer comprises the majority of the plant body and serves a wide
range of functions, including photosynthesis, selective nutrient uptake and storage,
and gravity sensing. Ground tissue patterning and maintenance in Arabidopsis are
controlled by a well-established gene network revolving around the key regulator
SHORT-ROOT (SHR). In contrast, it is completely unknown how ground tissue identity
is first specified from totipotent precursor cells in the embryo. The plant signaling
molecule auxin, acting through AUXIN RESPONSE FACTOR (ARF) transcription factors,
is critical for embryo patterning. The auxin effector ARF5/MONOPTEROS (MP) acts
both cell-autonomously and noncell-autonomously to control embryonic vascular
tissue formation and root initiation, respectively. Here we show that auxin response
and ARF activity cell-autonomously control the asymmetric division of the first
ground tissue cells. By identifying embryonic target genes, we show that MP transcriptionally
initiates the ground tissue lineage and acts upstream of the regulatory network
that controls ground tissue patterning and maintenance. Strikingly, whereas the
SHR network depends on MP, this MP function is, at least in part, SHR independent.
Our study therefore identifies auxin response as a regulator of ground tissue
specification in the embryonic root, and reveals that ground tissue initiation
and maintenance use different regulators and mechanisms. Moreover, our data provide
a framework for the simultaneous formation of multiple cell types by the same
transcriptional regulator.
author:
- first_name: Barbara
full_name: Möller, Barbara
last_name: Möller
- first_name: Colette
full_name: Ten Hove, Colette
last_name: Ten Hove
- first_name: Daoquan
full_name: Xiang, Daoquan
last_name: Xiang
- first_name: Nerys
full_name: Williams, Nerys
last_name: Williams
- first_name: Lorena
full_name: López, Lorena
last_name: López
- first_name: Saiko
full_name: Yoshida, Saiko
id: 2E46069C-F248-11E8-B48F-1D18A9856A87
last_name: Yoshida
- first_name: Margot
full_name: Smit, Margot
last_name: Smit
- first_name: Raju
full_name: Datla, Raju
last_name: Datla
- first_name: Dolf
full_name: Weijers, Dolf
last_name: Weijers
citation:
ama: Möller B, Ten Hove C, Xiang D, et al. Auxin response cell autonomously controls
ground tissue initiation in the early arabidopsis embryo. PNAS. 2017;114(12):E2533-E2539.
doi:10.1073/pnas.1616493114
apa: Möller, B., Ten Hove, C., Xiang, D., Williams, N., López, L., Yoshida, S.,
… Weijers, D. (2017). Auxin response cell autonomously controls ground tissue
initiation in the early arabidopsis embryo. PNAS. National Academy of Sciences.
https://doi.org/10.1073/pnas.1616493114
chicago: Möller, Barbara, Colette Ten Hove, Daoquan Xiang, Nerys Williams, Lorena
López, Saiko Yoshida, Margot Smit, Raju Datla, and Dolf Weijers. “Auxin Response
Cell Autonomously Controls Ground Tissue Initiation in the Early Arabidopsis Embryo.”
PNAS. National Academy of Sciences, 2017. https://doi.org/10.1073/pnas.1616493114.
ieee: B. Möller et al., “Auxin response cell autonomously controls ground
tissue initiation in the early arabidopsis embryo,” PNAS, vol. 114, no.
12. National Academy of Sciences, pp. E2533–E2539, 2017.
ista: Möller B, Ten Hove C, Xiang D, Williams N, López L, Yoshida S, Smit M, Datla
R, Weijers D. 2017. Auxin response cell autonomously controls ground tissue initiation
in the early arabidopsis embryo. PNAS. 114(12), E2533–E2539.
mla: Möller, Barbara, et al. “Auxin Response Cell Autonomously Controls Ground Tissue
Initiation in the Early Arabidopsis Embryo.” PNAS, vol. 114, no. 12, National
Academy of Sciences, 2017, pp. E2533–39, doi:10.1073/pnas.1616493114.
short: B. Möller, C. Ten Hove, D. Xiang, N. Williams, L. López, S. Yoshida, M. Smit,
R. Datla, D. Weijers, PNAS 114 (2017) E2533–E2539.
date_created: 2018-12-11T11:47:45Z
date_published: 2017-03-21T00:00:00Z
date_updated: 2021-01-12T08:08:02Z
day: '21'
department:
- _id: JiFr
doi: 10.1073/pnas.1616493114
external_id:
pmid:
- '28265057'
intvolume: ' 114'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373392/
month: '03'
oa: 1
oa_version: Submitted Version
page: E2533 - E2539
pmid: 1
publication: PNAS
publication_identifier:
issn:
- '00278424'
publication_status: published
publisher: National Academy of Sciences
publist_id: '7076'
quality_controlled: '1'
scopus_import: 1
status: public
title: Auxin response cell autonomously controls ground tissue initiation in the early
arabidopsis embryo
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 114
year: '2017'
...
---
_id: '658'
abstract:
- lang: eng
text: 'With the accelerated development of robot technologies, control becomes one
of the central themes of research. In traditional approaches, the controller,
by its internal functionality, finds appropriate actions on the basis of specific
objectives for the task at hand. While very successful in many applications, self-organized
control schemes seem to be favored in large complex systems with unknown dynamics
or which are difficult to model. Reasons are the expected scalability, robustness,
and resilience of self-organizing systems. The paper presents a self-learning
neurocontroller based on extrinsic differential plasticity introduced recently,
applying it to an anthropomorphic musculoskeletal robot arm with attached objects
of unknown physical dynamics. The central finding of the paper is the following
effect: by the mere feedback through the internal dynamics of the object, the
robot is learning to relate each of the objects with a very specific sensorimotor
pattern. Specifically, an attached pendulum pilots the arm into a circular motion,
a half-filled bottle produces axis oriented shaking behavior, a wheel is getting
rotated, and wiping patterns emerge automatically in a table-plus-brush setting.
By these object-specific dynamical patterns, the robot may be said to recognize
the object''s identity, or in other words, it discovers dynamical affordances
of objects. Furthermore, when including hand coordinates obtained from a camera,
a dedicated hand-eye coordination self-organizes spontaneously. These phenomena
are discussed from a specific dynamical system perspective. Central is the dedicated
working regime at the border to instability with its potentially infinite reservoir
of (limit cycle) attractors "waiting" to be excited. Besides converging
toward one of these attractors, variate behavior is also arising from a self-induced
attractor morphing driven by the learning rule. We claim that experimental investigations
with this anthropomorphic, self-learning robot not only generate interesting and
potentially useful behaviors, but may also help to better understand what subjective
human muscle feelings are, how they can be rooted in sensorimotor patterns, and
how these concepts may feed back on robotics.'
article_number: '00008'
article_processing_charge: Yes
author:
- first_name: Ralf
full_name: Der, Ralf
last_name: Der
- first_name: Georg S
full_name: Martius, Georg S
id: 3A276B68-F248-11E8-B48F-1D18A9856A87
last_name: Martius
citation:
ama: Der R, Martius GS. Self organized behavior generation for musculoskeletal robots.
Frontiers in Neurorobotics. 2017;11(MAR). doi:10.3389/fnbot.2017.00008
apa: Der, R., & Martius, G. S. (2017). Self organized behavior generation for
musculoskeletal robots. Frontiers in Neurorobotics. Frontiers Research
Foundation. https://doi.org/10.3389/fnbot.2017.00008
chicago: Der, Ralf, and Georg S Martius. “Self Organized Behavior Generation for
Musculoskeletal Robots.” Frontiers in Neurorobotics. Frontiers Research
Foundation, 2017. https://doi.org/10.3389/fnbot.2017.00008.
ieee: R. Der and G. S. Martius, “Self organized behavior generation for musculoskeletal
robots,” Frontiers in Neurorobotics, vol. 11, no. MAR. Frontiers Research
Foundation, 2017.
ista: Der R, Martius GS. 2017. Self organized behavior generation for musculoskeletal
robots. Frontiers in Neurorobotics. 11(MAR), 00008.
mla: Der, Ralf, and Georg S. Martius. “Self Organized Behavior Generation for Musculoskeletal
Robots.” Frontiers in Neurorobotics, vol. 11, no. MAR, 00008, Frontiers
Research Foundation, 2017, doi:10.3389/fnbot.2017.00008.
short: R. Der, G.S. Martius, Frontiers in Neurorobotics 11 (2017).
date_created: 2018-12-11T11:47:45Z
date_published: 2017-03-16T00:00:00Z
date_updated: 2021-01-12T08:08:04Z
day: '16'
ddc:
- '006'
department:
- _id: ChLa
- _id: GaTk
doi: 10.3389/fnbot.2017.00008
ec_funded: 1
file:
- access_level: open_access
checksum: b1bc43f96d1df3313c03032c2a46388d
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:18:49Z
date_updated: 2020-07-14T12:47:33Z
file_id: '5371'
file_name: IST-2017-903-v1+1_fnbot-11-00008.pdf
file_size: 8439566
relation: main_file
file_date_updated: 2020-07-14T12:47:33Z
has_accepted_license: '1'
intvolume: ' 11'
issue: MAR
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Frontiers in Neurorobotics
publication_identifier:
issn:
- '16625218'
publication_status: published
publisher: Frontiers Research Foundation
publist_id: '7078'
pubrep_id: '903'
quality_controlled: '1'
scopus_import: 1
status: public
title: Self organized behavior generation for musculoskeletal robots
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2EBD1598-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2017'
...
---
_id: '659'
abstract:
- lang: eng
text: Migration frequently involves Rac-mediated protrusion of lamellipodia, formed
by Arp2/3 complex-dependent branching thought to be crucial for force generation
and stability of these networks. The formins FMNL2 and FMNL3 are Cdc42 effectors
targeting to the lamellipodium tip and shown here to nucleate and elongate actin
filaments with complementary activities in vitro. In migrating B16-F1 melanoma
cells, both formins contribute to the velocity of lamellipodium protrusion. Loss
of FMNL2/3 function in melanoma cells and fibroblasts reduces lamellipodial width,
actin filament density and -bundling, without changing patterns of Arp2/3 complex
incorporation. Strikingly, in melanoma cells, FMNL2/3 gene inactivation almost
completely abolishes protrusion forces exerted by lamellipodia and modifies their
ultrastructural organization. Consistently, CRISPR/Cas-mediated depletion of FMNL2/3
in fibroblasts reduces both migration and capability of cells to move against
viscous media. Together, we conclude that force generation in lamellipodia strongly
depends on FMNL formin activity, operating in addition to Arp2/3 complex-dependent
filament branching.
article_number: '14832'
article_processing_charge: No
author:
- first_name: Frieda
full_name: Kage, Frieda
last_name: Kage
- first_name: Moritz
full_name: Winterhoff, Moritz
last_name: Winterhoff
- first_name: Vanessa
full_name: Dimchev, Vanessa
last_name: Dimchev
- first_name: Jan
full_name: Müller, Jan
id: AD07FDB4-0F61-11EA-8158-C4CC64CEAA8D
last_name: Müller
- first_name: Tobias
full_name: Thalheim, Tobias
last_name: Thalheim
- first_name: Anika
full_name: Freise, Anika
last_name: Freise
- first_name: Stefan
full_name: Brühmann, Stefan
last_name: Brühmann
- first_name: Jana
full_name: Kollasser, Jana
last_name: Kollasser
- first_name: Jennifer
full_name: Block, Jennifer
last_name: Block
- first_name: Georgi A
full_name: Dimchev, Georgi A
last_name: Dimchev
- first_name: Matthias
full_name: Geyer, Matthias
last_name: Geyer
- first_name: Hams
full_name: Schnittler, Hams
last_name: Schnittler
- first_name: Cord
full_name: Brakebusch, Cord
last_name: Brakebusch
- first_name: Theresia
full_name: Stradal, Theresia
last_name: Stradal
- first_name: Marie
full_name: Carlier, Marie
last_name: Carlier
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
- first_name: Josef
full_name: Käs, Josef
last_name: Käs
- first_name: Jan
full_name: Faix, Jan
last_name: Faix
- first_name: Klemens
full_name: Rottner, Klemens
last_name: Rottner
citation:
ama: Kage F, Winterhoff M, Dimchev V, et al. FMNL formins boost lamellipodial force
generation. Nature Communications. 2017;8. doi:10.1038/ncomms14832
apa: Kage, F., Winterhoff, M., Dimchev, V., Müller, J., Thalheim, T., Freise, A.,
… Rottner, K. (2017). FMNL formins boost lamellipodial force generation. Nature
Communications. Nature Publishing Group. https://doi.org/10.1038/ncomms14832
chicago: Kage, Frieda, Moritz Winterhoff, Vanessa Dimchev, Jan Müller, Tobias Thalheim,
Anika Freise, Stefan Brühmann, et al. “FMNL Formins Boost Lamellipodial Force
Generation.” Nature Communications. Nature Publishing Group, 2017. https://doi.org/10.1038/ncomms14832.
ieee: F. Kage et al., “FMNL formins boost lamellipodial force generation,”
Nature Communications, vol. 8. Nature Publishing Group, 2017.
ista: Kage F, Winterhoff M, Dimchev V, Müller J, Thalheim T, Freise A, Brühmann
S, Kollasser J, Block J, Dimchev GA, Geyer M, Schnittler H, Brakebusch C, Stradal
T, Carlier M, Sixt MK, Käs J, Faix J, Rottner K. 2017. FMNL formins boost lamellipodial
force generation. Nature Communications. 8, 14832.
mla: Kage, Frieda, et al. “FMNL Formins Boost Lamellipodial Force Generation.” Nature
Communications, vol. 8, 14832, Nature Publishing Group, 2017, doi:10.1038/ncomms14832.
short: F. Kage, M. Winterhoff, V. Dimchev, J. Müller, T. Thalheim, A. Freise, S.
Brühmann, J. Kollasser, J. Block, G.A. Dimchev, M. Geyer, H. Schnittler, C. Brakebusch,
T. Stradal, M. Carlier, M.K. Sixt, J. Käs, J. Faix, K. Rottner, Nature Communications
8 (2017).
date_created: 2018-12-11T11:47:46Z
date_published: 2017-03-22T00:00:00Z
date_updated: 2021-01-12T08:08:06Z
day: '22'
ddc:
- '570'
department:
- _id: MiSi
doi: 10.1038/ncomms14832
file:
- access_level: open_access
checksum: dae30190291c3630e8102d8714a8d23e
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:21Z
date_updated: 2020-07-14T12:47:34Z
file_id: '5072'
file_name: IST-2017-902-v1+1_Kage_et_al-2017-Nature_Communications.pdf
file_size: 9523746
relation: main_file
file_date_updated: 2020-07-14T12:47:34Z
has_accepted_license: '1'
intvolume: ' 8'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
issn:
- '20411723'
publication_status: published
publisher: Nature Publishing Group
publist_id: '7075'
pubrep_id: '902'
quality_controlled: '1'
scopus_import: 1
status: public
title: FMNL formins boost lamellipodial force generation
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2017'
...
---
_id: '660'
abstract:
- lang: eng
text: Growing microtubules are protected from depolymerization by the presence of
a GTP or GDP/Pi cap. End-binding proteins of the EB1 family bind to the stabilizing
cap, allowing monitoring of its size in real time. The cap size has been shown
to correlate with instantaneous microtubule stability. Here we have quantitatively
characterized the properties of cap size fluctuations during steadystate growth
and have developed a theory predicting their timescale and amplitude from the
kinetics of microtubule growth and cap maturation. In contrast to growth speed
fluctuations, cap size fluctuations show a characteristic timescale, which is
defined by the lifetime of the cap sites. Growth fluctuations affect the amplitude
of cap size fluctuations; however, cap size does not affect growth speed, indicating
that microtubules are far from instability during most of their time of growth.
Our theory provides the basis for a quantitative understanding of microtubule
stability fluctuations during steady-state growth.
acknowledgement: We thank Philippe Cluzel for helpful discussions and Gunnar Pruessner
for data analysis advice. This work was supported by the Francis Crick Institute,
which receives its core funding from Cancer Research UK Grant FC001163, Medical
Research Council Grant FC001163, and Wellcome Trust Grant FC001163. This work was
also supported by European Research Council Advanced Grant Project 323042 (to C.D.
and T.S.).
author:
- first_name: Jamie
full_name: Rickman, Jamie
last_name: Rickman
- first_name: Christian F
full_name: Düllberg, Christian F
id: 459064DC-F248-11E8-B48F-1D18A9856A87
last_name: Düllberg
orcid: 0000-0001-6335-9748
- first_name: Nicholas
full_name: Cade, Nicholas
last_name: Cade
- first_name: Lewis
full_name: Griffin, Lewis
last_name: Griffin
- first_name: Thomas
full_name: Surrey, Thomas
last_name: Surrey
citation:
ama: Rickman J, Düllberg CF, Cade N, Griffin L, Surrey T. Steady state EB cap size
fluctuations are determined by stochastic microtubule growth and maturation. PNAS.
2017;114(13):3427-3432. doi:10.1073/pnas.1620274114
apa: Rickman, J., Düllberg, C. F., Cade, N., Griffin, L., & Surrey, T. (2017).
Steady state EB cap size fluctuations are determined by stochastic microtubule
growth and maturation. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1620274114
chicago: Rickman, Jamie, Christian F Düllberg, Nicholas Cade, Lewis Griffin, and
Thomas Surrey. “Steady State EB Cap Size Fluctuations Are Determined by Stochastic
Microtubule Growth and Maturation.” PNAS. National Academy of Sciences,
2017. https://doi.org/10.1073/pnas.1620274114.
ieee: J. Rickman, C. F. Düllberg, N. Cade, L. Griffin, and T. Surrey, “Steady state
EB cap size fluctuations are determined by stochastic microtubule growth and maturation,”
PNAS, vol. 114, no. 13. National Academy of Sciences, pp. 3427–3432, 2017.
ista: Rickman J, Düllberg CF, Cade N, Griffin L, Surrey T. 2017. Steady state EB
cap size fluctuations are determined by stochastic microtubule growth and maturation.
PNAS. 114(13), 3427–3432.
mla: Rickman, Jamie, et al. “Steady State EB Cap Size Fluctuations Are Determined
by Stochastic Microtubule Growth and Maturation.” PNAS, vol. 114, no. 13,
National Academy of Sciences, 2017, pp. 3427–32, doi:10.1073/pnas.1620274114.
short: J. Rickman, C.F. Düllberg, N. Cade, L. Griffin, T. Surrey, PNAS 114 (2017)
3427–3432.
date_created: 2018-12-11T11:47:46Z
date_published: 2017-03-28T00:00:00Z
date_updated: 2021-01-12T08:08:09Z
day: '28'
department:
- _id: MaLo
doi: 10.1073/pnas.1620274114
external_id:
pmid:
- '28280102'
intvolume: ' 114'
issue: '13'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380103/
month: '03'
oa: 1
oa_version: Submitted Version
page: 3427 - 3432
pmid: 1
publication: PNAS
publication_identifier:
issn:
- '00278424'
publication_status: published
publisher: National Academy of Sciences
publist_id: '7073'
quality_controlled: '1'
scopus_import: 1
status: public
title: Steady state EB cap size fluctuations are determined by stochastic microtubule
growth and maturation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 114
year: '2017'
...
---
_id: '661'
abstract:
- lang: eng
text: During embryonic development, mechanical forces are essential for cellular
rearrangements driving tissue morphogenesis. Here, we show that in the early zebrafish
embryo, friction forces are generated at the interface between anterior axial
mesoderm (prechordal plate, ppl) progenitors migrating towards the animal pole
and neurectoderm progenitors moving in the opposite direction towards the vegetal
pole of the embryo. These friction forces lead to global rearrangement of cells
within the neurectoderm and determine the position of the neural anlage. Using
a combination of experiments and simulations, we show that this process depends
on hydrodynamic coupling between neurectoderm and ppl as a result of E-cadherin-mediated
adhesion between those tissues. Our data thus establish the emergence of friction
forces at the interface between moving tissues as a critical force-generating
process shaping the embryo.
acknowledged_ssus:
- _id: SSU
author:
- first_name: Michael
full_name: Smutny, Michael
id: 3FE6E4E8-F248-11E8-B48F-1D18A9856A87
last_name: Smutny
orcid: 0000-0002-5920-9090
- first_name: Zsuzsa
full_name: Ákos, Zsuzsa
last_name: Ákos
- first_name: Silvia
full_name: Grigolon, Silvia
last_name: Grigolon
- first_name: Shayan
full_name: Shamipour, Shayan
id: 40B34FE2-F248-11E8-B48F-1D18A9856A87
last_name: Shamipour
- first_name: Verena
full_name: Ruprecht, Verena
last_name: Ruprecht
- first_name: Daniel
full_name: Capek, Daniel
id: 31C42484-F248-11E8-B48F-1D18A9856A87
last_name: Capek
orcid: 0000-0001-5199-9940
- first_name: Martin
full_name: Behrndt, Martin
id: 3ECECA3A-F248-11E8-B48F-1D18A9856A87
last_name: Behrndt
- first_name: Ekaterina
full_name: Papusheva, Ekaterina
id: 41DB591E-F248-11E8-B48F-1D18A9856A87
last_name: Papusheva
- first_name: Masazumi
full_name: Tada, Masazumi
last_name: Tada
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
- first_name: Tamás
full_name: Vicsek, Tamás
last_name: Vicsek
- first_name: Guillaume
full_name: Salbreux, Guillaume
last_name: Salbreux
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Smutny M, Ákos Z, Grigolon S, et al. Friction forces position the neural anlage.
Nature Cell Biology. 2017;19:306-317. doi:10.1038/ncb3492
apa: Smutny, M., Ákos, Z., Grigolon, S., Shamipour, S., Ruprecht, V., Capek, D.,
… Heisenberg, C.-P. J. (2017). Friction forces position the neural anlage. Nature
Cell Biology. Nature Publishing Group. https://doi.org/10.1038/ncb3492
chicago: Smutny, Michael, Zsuzsa Ákos, Silvia Grigolon, Shayan Shamipour, Verena
Ruprecht, Daniel Capek, Martin Behrndt, et al. “Friction Forces Position the Neural
Anlage.” Nature Cell Biology. Nature Publishing Group, 2017. https://doi.org/10.1038/ncb3492.
ieee: M. Smutny et al., “Friction forces position the neural anlage,” Nature
Cell Biology, vol. 19. Nature Publishing Group, pp. 306–317, 2017.
ista: Smutny M, Ákos Z, Grigolon S, Shamipour S, Ruprecht V, Capek D, Behrndt M,
Papusheva E, Tada M, Hof B, Vicsek T, Salbreux G, Heisenberg C-PJ. 2017. Friction
forces position the neural anlage. Nature Cell Biology. 19, 306–317.
mla: Smutny, Michael, et al. “Friction Forces Position the Neural Anlage.” Nature
Cell Biology, vol. 19, Nature Publishing Group, 2017, pp. 306–17, doi:10.1038/ncb3492.
short: M. Smutny, Z. Ákos, S. Grigolon, S. Shamipour, V. Ruprecht, D. Capek, M.
Behrndt, E. Papusheva, M. Tada, B. Hof, T. Vicsek, G. Salbreux, C.-P.J. Heisenberg,
Nature Cell Biology 19 (2017) 306–317.
date_created: 2018-12-11T11:47:46Z
date_published: 2017-03-27T00:00:00Z
date_updated: 2024-03-25T23:30:21Z
day: '27'
department:
- _id: CaHe
- _id: BjHo
- _id: Bio
doi: 10.1038/ncb3492
ec_funded: 1
external_id:
pmid:
- '28346437'
intvolume: ' 19'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://europepmc.org/articles/pmc5635970
month: '03'
oa: 1
oa_version: Submitted Version
page: 306 - 317
pmid: 1
project:
- _id: 25152F3A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '306589'
name: Decoding the complexity of turbulence at its origin
- _id: 252ABD0A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I 930-B20
name: Control of Epithelial Cell Layer Spreading in Zebrafish
publication: Nature Cell Biology
publication_identifier:
issn:
- '14657392'
publication_status: published
publisher: Nature Publishing Group
publist_id: '7074'
quality_controlled: '1'
related_material:
record:
- id: '50'
relation: dissertation_contains
status: public
- id: '8350'
relation: dissertation_contains
status: public
scopus_import: 1
status: public
title: Friction forces position the neural anlage
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 19
year: '2017'
...
---
_id: '1433'
abstract:
- lang: eng
text: Phat is an open-source C. ++ library for the computation of persistent homology
by matrix reduction, targeted towards developers of software for topological data
analysis. We aim for a simple generic design that decouples algorithms from data
structures without sacrificing efficiency or user-friendliness. We provide numerous
different reduction strategies as well as data types to store and manipulate the
boundary matrix. We compare the different combinations through extensive experimental
evaluation and identify optimization techniques that work well in practical situations.
We also compare our software with various other publicly available libraries for
persistent homology.
article_processing_charge: No
article_type: original
author:
- first_name: Ulrich
full_name: Bauer, Ulrich
last_name: Bauer
- first_name: Michael
full_name: Kerber, Michael
last_name: Kerber
- first_name: Jan
full_name: Reininghaus, Jan
last_name: Reininghaus
- first_name: Hubert
full_name: Wagner, Hubert
id: 379CA8B8-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
citation:
ama: Bauer U, Kerber M, Reininghaus J, Wagner H. Phat - Persistent homology algorithms
toolbox. Journal of Symbolic Computation. 2017;78:76-90. doi:10.1016/j.jsc.2016.03.008
apa: Bauer, U., Kerber, M., Reininghaus, J., & Wagner, H. (2017). Phat - Persistent
homology algorithms toolbox. Journal of Symbolic Computation. Academic
Press. https://doi.org/10.1016/j.jsc.2016.03.008
chicago: Bauer, Ulrich, Michael Kerber, Jan Reininghaus, and Hubert Wagner. “Phat
- Persistent Homology Algorithms Toolbox.” Journal of Symbolic Computation.
Academic Press, 2017. https://doi.org/10.1016/j.jsc.2016.03.008.
ieee: U. Bauer, M. Kerber, J. Reininghaus, and H. Wagner, “Phat - Persistent homology
algorithms toolbox,” Journal of Symbolic Computation, vol. 78. Academic
Press, pp. 76–90, 2017.
ista: Bauer U, Kerber M, Reininghaus J, Wagner H. 2017. Phat - Persistent homology
algorithms toolbox. Journal of Symbolic Computation. 78, 76–90.
mla: Bauer, Ulrich, et al. “Phat - Persistent Homology Algorithms Toolbox.” Journal
of Symbolic Computation, vol. 78, Academic Press, 2017, pp. 76–90, doi:10.1016/j.jsc.2016.03.008.
short: U. Bauer, M. Kerber, J. Reininghaus, H. Wagner, Journal of Symbolic Computation
78 (2017) 76–90.
date_created: 2018-12-11T11:51:59Z
date_published: 2017-01-01T00:00:00Z
date_updated: 2023-09-20T09:42:40Z
day: '01'
department:
- _id: HeEd
doi: 10.1016/j.jsc.2016.03.008
ec_funded: 1
external_id:
isi:
- '000384396000005'
intvolume: ' 78'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.jsc.2016.03.008
month: '01'
oa: 1
oa_version: Published Version
page: 76 - 90
project:
- _id: 255D761E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '318493'
name: Topological Complex Systems
publication: Journal of Symbolic Computation
publication_identifier:
issn:
- ' 07477171'
publication_status: published
publisher: Academic Press
publist_id: '5765'
quality_controlled: '1'
related_material:
record:
- id: '10894'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Phat - Persistent homology algorithms toolbox
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 78
year: '2017'
...
---
_id: '1528'
abstract:
- lang: eng
text: 'We consider N×N Hermitian random matrices H consisting of blocks of size
M≥N6/7. The matrix elements are i.i.d. within the blocks, close to a Gaussian
in the four moment matching sense, but their distribution varies from block to
block to form a block-band structure, with an essential band width M. We show
that the entries of the Green’s function G(z)=(H−z)−1 satisfy the local semicircle
law with spectral parameter z=E+iη down to the real axis for any η≫N−1, using
a combination of the supersymmetry method inspired by Shcherbina (J Stat Phys
155(3): 466–499, 2014) and the Green’s function comparison strategy. Previous
estimates were valid only for η≫M−1. The new estimate also implies that the eigenvectors
in the middle of the spectrum are fully delocalized.'
acknowledgement: "Z. Bao was supported by ERC Advanced Grant RANMAT No. 338804; L.
Erdős was partially supported by ERC Advanced Grant RANMAT No. 338804.\r\nOpen access
funding provided by Institute of Science and Technology (IST Austria). The authors
are very grateful to the anonymous referees for careful reading and valuable comments,
which helped to improve the organization."
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Zhigang
full_name: Bao, Zhigang
id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
last_name: Bao
orcid: 0000-0003-3036-1475
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
citation:
ama: Bao Z, Erdös L. Delocalization for a class of random block band matrices. Probability
Theory and Related Fields. 2017;167(3-4):673-776. doi:10.1007/s00440-015-0692-y
apa: Bao, Z., & Erdös, L. (2017). Delocalization for a class of random block
band matrices. Probability Theory and Related Fields. Springer. https://doi.org/10.1007/s00440-015-0692-y
chicago: Bao, Zhigang, and László Erdös. “Delocalization for a Class of Random Block
Band Matrices.” Probability Theory and Related Fields. Springer, 2017.
https://doi.org/10.1007/s00440-015-0692-y.
ieee: Z. Bao and L. Erdös, “Delocalization for a class of random block band matrices,”
Probability Theory and Related Fields, vol. 167, no. 3–4. Springer, pp.
673–776, 2017.
ista: Bao Z, Erdös L. 2017. Delocalization for a class of random block band matrices.
Probability Theory and Related Fields. 167(3–4), 673–776.
mla: Bao, Zhigang, and László Erdös. “Delocalization for a Class of Random Block
Band Matrices.” Probability Theory and Related Fields, vol. 167, no. 3–4,
Springer, 2017, pp. 673–776, doi:10.1007/s00440-015-0692-y.
short: Z. Bao, L. Erdös, Probability Theory and Related Fields 167 (2017) 673–776.
date_created: 2018-12-11T11:52:32Z
date_published: 2017-04-01T00:00:00Z
date_updated: 2023-09-20T09:42:12Z
day: '01'
ddc:
- '530'
department:
- _id: LaEr
doi: 10.1007/s00440-015-0692-y
ec_funded: 1
external_id:
isi:
- '000398842700004'
file:
- access_level: open_access
checksum: 67afa85ff1e220cbc1f9f477a828513c
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:05Z
date_updated: 2020-07-14T12:45:00Z
file_id: '4665'
file_name: IST-2016-489-v1+1_s00440-015-0692-y.pdf
file_size: 1615755
relation: main_file
file_date_updated: 2020-07-14T12:45:00Z
has_accepted_license: '1'
intvolume: ' 167'
isi: 1
issue: 3-4
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 673 - 776
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
publication: Probability Theory and Related Fields
publication_identifier:
issn:
- '01788051'
publication_status: published
publisher: Springer
publist_id: '5644'
pubrep_id: '489'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Delocalization for a class of random block band matrices
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 167
year: '2017'
...
---
_id: '13160'
abstract:
- lang: eng
text: "Transforming deterministic ω\r\n-automata into deterministic parity automata
is traditionally done using variants of appearance records. We present a more
efficient variant of this approach, tailored to Rabin automata, and several optimizations
applicable to all appearance records. We compare the methods experimentally and
find out that our method produces smaller automata than previous approaches. Moreover,
the experiments demonstrate the potential of our method for LTL synthesis, using
LTL-to-Rabin translators. It leads to significantly smaller parity automata when
compared to state-of-the-art approaches on complex formulae."
acknowledgement: This work is partially funded by the DFG project “Verified Model
Checkers” and by the Czech Science Foundation, grant No. P202/12/G061.
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
- first_name: Tobias
full_name: Meggendorfer, Tobias
id: b21b0c15-30a2-11eb-80dc-f13ca25802e1
last_name: Meggendorfer
orcid: 0000-0002-1712-2165
- first_name: Clara
full_name: Waldmann, Clara
last_name: Waldmann
- first_name: Maximilian
full_name: Weininger, Maximilian
last_name: Weininger
citation:
ama: 'Kretinsky J, Meggendorfer T, Waldmann C, Weininger M. Index appearance record
for transforming Rabin automata into parity automata. In: Tools and Algorithms
for the Construction and Analysis of Systems. Vol 10205. Springer; 2017:443-460.
doi:10.1007/978-3-662-54577-5_26'
apa: 'Kretinsky, J., Meggendorfer, T., Waldmann, C., & Weininger, M. (2017).
Index appearance record for transforming Rabin automata into parity automata.
In Tools and Algorithms for the Construction and Analysis of Systems (Vol.
10205, pp. 443–460). Uppsala, Sweden: Springer. https://doi.org/10.1007/978-3-662-54577-5_26'
chicago: Kretinsky, Jan, Tobias Meggendorfer, Clara Waldmann, and Maximilian Weininger.
“Index Appearance Record for Transforming Rabin Automata into Parity Automata.”
In Tools and Algorithms for the Construction and Analysis of Systems, 10205:443–60.
Springer, 2017. https://doi.org/10.1007/978-3-662-54577-5_26.
ieee: J. Kretinsky, T. Meggendorfer, C. Waldmann, and M. Weininger, “Index appearance
record for transforming Rabin automata into parity automata,” in Tools and
Algorithms for the Construction and Analysis of Systems, Uppsala, Sweden,
2017, vol. 10205, pp. 443–460.
ista: 'Kretinsky J, Meggendorfer T, Waldmann C, Weininger M. 2017. Index appearance
record for transforming Rabin automata into parity automata. Tools and Algorithms
for the Construction and Analysis of Systems. TACAS: Tools and Algorithms for
the Construction and Analysis of Systems, LNCS, vol. 10205, 443–460.'
mla: Kretinsky, Jan, et al. “Index Appearance Record for Transforming Rabin Automata
into Parity Automata.” Tools and Algorithms for the Construction and Analysis
of Systems, vol. 10205, Springer, 2017, pp. 443–60, doi:10.1007/978-3-662-54577-5_26.
short: J. Kretinsky, T. Meggendorfer, C. Waldmann, M. Weininger, in:, Tools and
Algorithms for the Construction and Analysis of Systems, Springer, 2017, pp. 443–460.
conference:
end_date: 2017-04-29
location: Uppsala, Sweden
name: 'TACAS: Tools and Algorithms for the Construction and Analysis of Systems'
start_date: 2017-04-22
date_created: 2023-06-21T13:21:14Z
date_published: 2017-03-31T00:00:00Z
date_updated: 2023-06-21T13:29:46Z
day: '31'
department:
- _id: KrCh
doi: 10.1007/978-3-662-54577-5_26
external_id:
arxiv:
- '1701.05738'
intvolume: ' 10205'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1701.05738
month: '03'
oa: 1
oa_version: Preprint
page: 443-460
publication: Tools and Algorithms for the Construction and Analysis of Systems
publication_identifier:
eisbn:
- '9783662545775'
eissn:
- 1611-3349
isbn:
- '9783662545768'
issn:
- 0302-9743
publication_status: published
publisher: Springer
quality_controlled: '1'
status: public
title: Index appearance record for transforming Rabin automata into parity automata
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10205
year: '2017'
...
---
_id: '1336'
abstract:
- lang: eng
text: Evolutionary algorithms (EAs) form a popular optimisation paradigm inspired
by natural evolution. In recent years the field of evolutionary computation has
developed a rigorous analytical theory to analyse the runtimes of EAs on many
illustrative problems. Here we apply this theory to a simple model of natural
evolution. In the Strong Selection Weak Mutation (SSWM) evolutionary regime the
time between occurrences of new mutations is much longer than the time it takes
for a mutated genotype to take over the population. In this situation, the population
only contains copies of one genotype and evolution can be modelled as a stochastic
process evolving one genotype by means of mutation and selection between the resident
and the mutated genotype. The probability of accepting the mutated genotype then
depends on the change in fitness. We study this process, SSWM, from an algorithmic
perspective, quantifying its expected optimisation time for various parameters
and investigating differences to a similar evolutionary algorithm, the well-known
(1+1) EA. We show that SSWM can have a moderate advantage over the (1+1) EA at
crossing fitness valleys and study an example where SSWM outperforms the (1+1)
EA by taking advantage of information on the fitness gradient.
article_processing_charge: No
author:
- first_name: Tiago
full_name: Paixao, Tiago
id: 2C5658E6-F248-11E8-B48F-1D18A9856A87
last_name: Paixao
orcid: 0000-0003-2361-3953
- first_name: Jorge
full_name: Pérez Heredia, Jorge
last_name: Pérez Heredia
- first_name: Dirk
full_name: Sudholt, Dirk
last_name: Sudholt
- first_name: Barbora
full_name: Trubenova, Barbora
id: 42302D54-F248-11E8-B48F-1D18A9856A87
last_name: Trubenova
orcid: 0000-0002-6873-2967
citation:
ama: Paixao T, Pérez Heredia J, Sudholt D, Trubenova B. Towards a runtime comparison
of natural and artificial evolution. Algorithmica. 2017;78(2):681-713.
doi:10.1007/s00453-016-0212-1
apa: Paixao, T., Pérez Heredia, J., Sudholt, D., & Trubenova, B. (2017). Towards
a runtime comparison of natural and artificial evolution. Algorithmica.
Springer. https://doi.org/10.1007/s00453-016-0212-1
chicago: Paixao, Tiago, Jorge Pérez Heredia, Dirk Sudholt, and Barbora Trubenova.
“Towards a Runtime Comparison of Natural and Artificial Evolution.” Algorithmica.
Springer, 2017. https://doi.org/10.1007/s00453-016-0212-1.
ieee: T. Paixao, J. Pérez Heredia, D. Sudholt, and B. Trubenova, “Towards a runtime
comparison of natural and artificial evolution,” Algorithmica, vol. 78,
no. 2. Springer, pp. 681–713, 2017.
ista: Paixao T, Pérez Heredia J, Sudholt D, Trubenova B. 2017. Towards a runtime
comparison of natural and artificial evolution. Algorithmica. 78(2), 681–713.
mla: Paixao, Tiago, et al. “Towards a Runtime Comparison of Natural and Artificial
Evolution.” Algorithmica, vol. 78, no. 2, Springer, 2017, pp. 681–713,
doi:10.1007/s00453-016-0212-1.
short: T. Paixao, J. Pérez Heredia, D. Sudholt, B. Trubenova, Algorithmica 78 (2017)
681–713.
date_created: 2018-12-11T11:51:27Z
date_published: 2017-06-01T00:00:00Z
date_updated: 2023-09-20T11:14:42Z
day: '01'
ddc:
- '576'
department:
- _id: NiBa
- _id: CaGu
doi: 10.1007/s00453-016-0212-1
ec_funded: 1
external_id:
isi:
- '000400379500013'
file:
- access_level: open_access
checksum: 7873f665a0c598ac747c908f34cb14b9
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:10:19Z
date_updated: 2020-07-14T12:44:44Z
file_id: '4805'
file_name: IST-2016-658-v1+1_s00453-016-0212-1.pdf
file_size: 710206
relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: ' 78'
isi: 1
issue: '2'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 681 - 713
project:
- _id: 25B1EC9E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '618091'
name: Speed of Adaptation in Population Genetics and Evolutionary Computation
publication: Algorithmica
publication_identifier:
issn:
- '01784617'
publication_status: published
publisher: Springer
publist_id: '5931'
pubrep_id: '658'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Towards a runtime comparison of natural and artificial evolution
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 78
year: '2017'
...
---
_id: '1337'
abstract:
- lang: eng
text: We consider the local eigenvalue distribution of large self-adjoint N×N random
matrices H=H∗ with centered independent entries. In contrast to previous works
the matrix of variances sij=\mathbbmE|hij|2 is not assumed to be stochastic. Hence
the density of states is not the Wigner semicircle law. Its possible shapes are
described in the companion paper (Ajanki et al. in Quadratic Vector Equations
on the Complex Upper Half Plane. arXiv:1506.05095). We show that as N grows, the
resolvent, G(z)=(H−z)−1, converges to a diagonal matrix, diag(m(z)), where m(z)=(m1(z),…,mN(z))
solves the vector equation −1/mi(z)=z+∑jsijmj(z) that has been analyzed in Ajanki
et al. (Quadratic Vector Equations on the Complex Upper Half Plane. arXiv:1506.05095).
We prove a local law down to the smallest spectral resolution scale, and bulk
universality for both real symmetric and complex hermitian symmetry classes.
acknowledgement: 'Open access funding provided by Institute of Science and Technology
(IST Austria). '
article_processing_charge: Yes (via OA deal)
author:
- first_name: Oskari H
full_name: Ajanki, Oskari H
id: 36F2FB7E-F248-11E8-B48F-1D18A9856A87
last_name: Ajanki
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Torben H
full_name: Krüger, Torben H
id: 3020C786-F248-11E8-B48F-1D18A9856A87
last_name: Krüger
orcid: 0000-0002-4821-3297
citation:
ama: Ajanki OH, Erdös L, Krüger TH. Universality for general Wigner-type matrices.
Probability Theory and Related Fields. 2017;169(3-4):667-727. doi:10.1007/s00440-016-0740-2
apa: Ajanki, O. H., Erdös, L., & Krüger, T. H. (2017). Universality for general
Wigner-type matrices. Probability Theory and Related Fields. Springer.
https://doi.org/10.1007/s00440-016-0740-2
chicago: Ajanki, Oskari H, László Erdös, and Torben H Krüger. “Universality for
General Wigner-Type Matrices.” Probability Theory and Related Fields. Springer,
2017. https://doi.org/10.1007/s00440-016-0740-2.
ieee: O. H. Ajanki, L. Erdös, and T. H. Krüger, “Universality for general Wigner-type
matrices,” Probability Theory and Related Fields, vol. 169, no. 3–4. Springer,
pp. 667–727, 2017.
ista: Ajanki OH, Erdös L, Krüger TH. 2017. Universality for general Wigner-type
matrices. Probability Theory and Related Fields. 169(3–4), 667–727.
mla: Ajanki, Oskari H., et al. “Universality for General Wigner-Type Matrices.”
Probability Theory and Related Fields, vol. 169, no. 3–4, Springer, 2017,
pp. 667–727, doi:10.1007/s00440-016-0740-2.
short: O.H. Ajanki, L. Erdös, T.H. Krüger, Probability Theory and Related Fields
169 (2017) 667–727.
date_created: 2018-12-11T11:51:27Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2023-09-20T11:14:17Z
day: '01'
ddc:
- '510'
- '530'
department:
- _id: LaEr
doi: 10.1007/s00440-016-0740-2
ec_funded: 1
external_id:
isi:
- '000414358400002'
file:
- access_level: open_access
checksum: 29f5a72c3f91e408aeb9e78344973803
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:25Z
date_updated: 2020-07-14T12:44:44Z
file_id: '4686'
file_name: IST-2017-657-v1+2_s00440-016-0740-2.pdf
file_size: 988843
relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: ' 169'
isi: 1
issue: 3-4
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 667 - 727
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
name: IST Austria Open Access Fund
publication: Probability Theory and Related Fields
publication_identifier:
issn:
- '01788051'
publication_status: published
publisher: Springer
publist_id: '5930'
pubrep_id: '657'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Universality for general Wigner-type matrices
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 169
year: '2017'
...
---
_id: '1338'
abstract:
- lang: eng
text: We present a computer-aided programming approach to concurrency. The approach
allows programmers to program assuming a friendly, non-preemptive scheduler, and
our synthesis procedure inserts synchronization to ensure that the final program
works even with a preemptive scheduler. The correctness specification is implicit,
inferred from the non-preemptive behavior. Let us consider sequences of calls
that the program makes to an external interface. The specification requires that
any such sequence produced under a preemptive scheduler should be included in
the set of sequences produced under a non-preemptive scheduler. We guarantee that
our synthesis does not introduce deadlocks and that the synchronization inserted
is optimal w.r.t. a given objective function. The solution is based on a finitary
abstraction, an algorithm for bounded language inclusion modulo an independence
relation, and generation of a set of global constraints over synchronization placements.
Each model of the global constraints set corresponds to a correctness-ensuring
synchronization placement. The placement that is optimal w.r.t. the given objective
function is chosen as the synchronization solution. We apply the approach to device-driver
programming, where the driver threads call the software interface of the device
and the API provided by the operating system. Our experiments demonstrate that
our synthesis method is precise and efficient. The implicit specification helped
us find one concurrency bug previously missed when model-checking using an explicit,
user-provided specification. We implemented objective functions for coarse-grained
and fine-grained locking and observed that different synchronization placements
are produced for our experiments, favoring a minimal number of synchronization
operations or maximum concurrency, respectively.
article_processing_charge: No
author:
- first_name: Pavol
full_name: Cerny, Pavol
id: 4DCBEFFE-F248-11E8-B48F-1D18A9856A87
last_name: Cerny
- first_name: Edmund
full_name: Clarke, Edmund
last_name: Clarke
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Arjun
full_name: Radhakrishna, Arjun
id: 3B51CAC4-F248-11E8-B48F-1D18A9856A87
last_name: Radhakrishna
- first_name: Leonid
full_name: Ryzhyk, Leonid
last_name: Ryzhyk
- first_name: Roopsha
full_name: Samanta, Roopsha
id: 3D2AAC08-F248-11E8-B48F-1D18A9856A87
last_name: Samanta
- first_name: Thorsten
full_name: Tarrach, Thorsten
id: 3D6E8F2C-F248-11E8-B48F-1D18A9856A87
last_name: Tarrach
orcid: 0000-0003-4409-8487
citation:
ama: Cerny P, Clarke E, Henzinger TA, et al. From non-preemptive to preemptive scheduling
using synchronization synthesis. Formal Methods in System Design. 2017;50(2-3):97-139.
doi:10.1007/s10703-016-0256-5
apa: Cerny, P., Clarke, E., Henzinger, T. A., Radhakrishna, A., Ryzhyk, L., Samanta,
R., & Tarrach, T. (2017). From non-preemptive to preemptive scheduling using
synchronization synthesis. Formal Methods in System Design. Springer. https://doi.org/10.1007/s10703-016-0256-5
chicago: Cerny, Pavol, Edmund Clarke, Thomas A Henzinger, Arjun Radhakrishna, Leonid
Ryzhyk, Roopsha Samanta, and Thorsten Tarrach. “From Non-Preemptive to Preemptive
Scheduling Using Synchronization Synthesis.” Formal Methods in System Design.
Springer, 2017. https://doi.org/10.1007/s10703-016-0256-5.
ieee: P. Cerny et al., “From non-preemptive to preemptive scheduling using
synchronization synthesis,” Formal Methods in System Design, vol. 50, no.
2–3. Springer, pp. 97–139, 2017.
ista: Cerny P, Clarke E, Henzinger TA, Radhakrishna A, Ryzhyk L, Samanta R, Tarrach
T. 2017. From non-preemptive to preemptive scheduling using synchronization synthesis.
Formal Methods in System Design. 50(2–3), 97–139.
mla: Cerny, Pavol, et al. “From Non-Preemptive to Preemptive Scheduling Using Synchronization
Synthesis.” Formal Methods in System Design, vol. 50, no. 2–3, Springer,
2017, pp. 97–139, doi:10.1007/s10703-016-0256-5.
short: P. Cerny, E. Clarke, T.A. Henzinger, A. Radhakrishna, L. Ryzhyk, R. Samanta,
T. Tarrach, Formal Methods in System Design 50 (2017) 97–139.
date_created: 2018-12-11T11:51:27Z
date_published: 2017-06-01T00:00:00Z
date_updated: 2023-09-20T11:13:51Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1007/s10703-016-0256-5
ec_funded: 1
external_id:
isi:
- '000399888900001'
file:
- access_level: open_access
checksum: 1163dfd997e8212c789525d4178b1653
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:13:05Z
date_updated: 2020-07-14T12:44:44Z
file_id: '4985'
file_name: IST-2016-656-v1+1_s10703-016-0256-5.pdf
file_size: 1416170
relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: ' 50'
isi: 1
issue: 2-3
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 97 - 139
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
name: IST Austria Open Access Fund
publication: Formal Methods in System Design
publication_status: published
publisher: Springer
publist_id: '5929'
pubrep_id: '656'
quality_controlled: '1'
related_material:
record:
- id: '1729'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: From non-preemptive to preemptive scheduling using synchronization synthesis
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 50
year: '2017'
...
---
_id: '1351'
abstract:
- lang: eng
text: The behaviour of gene regulatory networks (GRNs) is typically analysed using
simulation-based statistical testing-like methods. In this paper, we demonstrate
that we can replace this approach by a formal verification-like method that gives
higher assurance and scalability. We focus on Wagner’s weighted GRN model with
varying weights, which is used in evolutionary biology. In the model, weight parameters
represent the gene interaction strength that may change due to genetic mutations.
For a property of interest, we synthesise the constraints over the parameter space
that represent the set of GRNs satisfying the property. We experimentally show
that our parameter synthesis procedure computes the mutational robustness of GRNs—an
important problem of interest in evolutionary biology—more efficiently than the
classical simulation method. We specify the property in linear temporal logic.
We employ symbolic bounded model checking and SMT solving to compute the space
of GRNs that satisfy the property, which amounts to synthesizing a set of linear
constraints on the weights.
article_processing_charge: No
author:
- first_name: Mirco
full_name: Giacobbe, Mirco
id: 3444EA5E-F248-11E8-B48F-1D18A9856A87
last_name: Giacobbe
orcid: 0000-0001-8180-0904
- first_name: Calin C
full_name: Guet, Calin C
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
- first_name: Ashutosh
full_name: Gupta, Ashutosh
id: 335E5684-F248-11E8-B48F-1D18A9856A87
last_name: Gupta
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Tiago
full_name: Paixao, Tiago
id: 2C5658E6-F248-11E8-B48F-1D18A9856A87
last_name: Paixao
orcid: 0000-0003-2361-3953
- first_name: Tatjana
full_name: Petrov, Tatjana
id: 3D5811FC-F248-11E8-B48F-1D18A9856A87
last_name: Petrov
orcid: 0000-0002-9041-0905
citation:
ama: Giacobbe M, Guet CC, Gupta A, Henzinger TA, Paixao T, Petrov T. Model checking
the evolution of gene regulatory networks. Acta Informatica. 2017;54(8):765-787.
doi:10.1007/s00236-016-0278-x
apa: Giacobbe, M., Guet, C. C., Gupta, A., Henzinger, T. A., Paixao, T., & Petrov,
T. (2017). Model checking the evolution of gene regulatory networks. Acta Informatica.
Springer. https://doi.org/10.1007/s00236-016-0278-x
chicago: Giacobbe, Mirco, Calin C Guet, Ashutosh Gupta, Thomas A Henzinger, Tiago
Paixao, and Tatjana Petrov. “Model Checking the Evolution of Gene Regulatory Networks.”
Acta Informatica. Springer, 2017. https://doi.org/10.1007/s00236-016-0278-x.
ieee: M. Giacobbe, C. C. Guet, A. Gupta, T. A. Henzinger, T. Paixao, and T. Petrov,
“Model checking the evolution of gene regulatory networks,” Acta Informatica,
vol. 54, no. 8. Springer, pp. 765–787, 2017.
ista: Giacobbe M, Guet CC, Gupta A, Henzinger TA, Paixao T, Petrov T. 2017. Model
checking the evolution of gene regulatory networks. Acta Informatica. 54(8), 765–787.
mla: Giacobbe, Mirco, et al. “Model Checking the Evolution of Gene Regulatory Networks.”
Acta Informatica, vol. 54, no. 8, Springer, 2017, pp. 765–87, doi:10.1007/s00236-016-0278-x.
short: M. Giacobbe, C.C. Guet, A. Gupta, T.A. Henzinger, T. Paixao, T. Petrov, Acta
Informatica 54 (2017) 765–787.
date_created: 2018-12-11T11:51:32Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2025-05-28T11:57:04Z
day: '01'
ddc:
- '006'
- '576'
department:
- _id: ToHe
- _id: CaGu
- _id: NiBa
doi: 10.1007/s00236-016-0278-x
ec_funded: 1
external_id:
isi:
- '000414343200003'
file:
- access_level: open_access
checksum: 4e661d9135d7f8c342e8e258dee76f3e
content_type: application/pdf
creator: dernst
date_created: 2019-01-17T15:57:29Z
date_updated: 2020-07-14T12:44:46Z
file_id: '5841'
file_name: 2017_ActaInformatica_Giacobbe.pdf
file_size: 755241
relation: main_file
file_date_updated: 2020-07-14T12:44:46Z
has_accepted_license: '1'
intvolume: ' 54'
isi: 1
issue: '8'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 765 - 787
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 25B1EC9E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '618091'
name: Speed of Adaptation in Population Genetics and Evolutionary Computation
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
publication: Acta Informatica
publication_identifier:
issn:
- '00015903'
publication_status: published
publisher: Springer
publist_id: '5898'
pubrep_id: '649'
quality_controlled: '1'
related_material:
record:
- id: '1835'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Model checking the evolution of gene regulatory networks
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 54
year: '2017'
...