Revealing the mechanisms underlying drug interactions

Project Period: 2015-01-01 – 2017-09-30
Funding Organisation: FWF
Principal Investigator
Department(s)
Bollenbach Group
Grant Number
P27201-B22
Funding Organisation
FWF

16 Publications

2022 | Published | Journal Article | IST-REx-ID: 11341 | OA
Intron-mediated induction of phenotypic heterogeneity
M. Lukacisin, A. Espinosa-Cantú, M.T. Bollenbach, Nature 605 (2022) 113–118.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2021 | Published | Journal Article | IST-REx-ID: 8997 | OA
Minimal biophysical model of combined antibiotic action
B. Kavcic, G. Tkačik, M.T. Bollenbach, PLOS Computational Biology 17 (2021).
[Published Version] View | Files available | DOI | WoS
 
2021 | Published | Journal Article | IST-REx-ID: 10271 | OA
Uncovering Key Metabolic Determinants of the Drug Interactions Between Trimethoprim and Erythromycin in Escherichia coli
Q. Qi, S.A. Angermayr, M.T. Bollenbach, Frontiers in Microbiology 12 (2021).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2020 | Published | Preprint | IST-REx-ID: 7673 | OA
A minimal biophysical model of combined antibiotic action
B. Kavcic, G. Tkačik, M.T. Bollenbach, BioRxiv (2020).
[Preprint] View | Files available | DOI | Download Preprint (ext.)
 
2020 | Published | Journal Article | IST-REx-ID: 8037 | OA
Highly parallel lab evolution reveals that epistasis can curb the evolution of antibiotic resistance
M. Lukacisinova, B. Fernando, M.T. Bollenbach, Nature Communications 11 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2020 | Published | Journal Article | IST-REx-ID: 8250 | OA
Mechanisms of drug interactions between translation-inhibiting antibiotics
B. Kavcic, G. Tkačik, M.T. Bollenbach, Nature Communications 11 (2020).
[Published Version] View | Files available | DOI | WoS
 
2019 | Published | Journal Article | IST-REx-ID: 6046 | OA
Temporal order and precision of complex stress responses in individual bacteria
K. Mitosch, G. Rieckh, M.T. Bollenbach, Molecular Systems Biology 15 (2019).
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
2019 | Published | Journal Article | IST-REx-ID: 7026 | OA
Emergent gene expression responses to drug combinations predict higher-order drug interactions
M. Lukacisin, M.T. Bollenbach, Cell Systems 9 (2019) 423-433.e1-e3.
[Published Version] View | Files available | DOI | WoS
 
2017 | Published | Journal Article | IST-REx-ID: 822 | OA
Interaction networks, ecological stability, and collective antibiotic tolerance in polymicrobial infections
M. de Vos, M.P. Zagórski, A. Mcnally, M.T. Bollenbach, PNAS 114 (2017) 10666–10671.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
2017 | Published | Journal Article | IST-REx-ID: 666 | OA
Noisy response to antibiotic stress predicts subsequent single cell survival in an acidic environment
K. Mitosch, G. Rieckh, M.T. Bollenbach, Cell Systems 4 (2017) 393–403.
[Published Version] View | Files available | DOI
 
2017 | Published | Journal Article | IST-REx-ID: 679 | OA
The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection
F. Ebner, V. Sedlyarov, S. Tasciyan, M. Ivin, F. Kratochvill, N. Gratz, L. Kenner, A. Villunger, M.K. Sixt, P. Kovarik, The Journal of Clinical Investigation 127 (2017) 2051–2065.
[Submitted Version] View | Files available | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
2017 | Published | Journal Article | IST-REx-ID: 713 | OA
Mapping the mouse Allelome reveals tissue specific regulation of allelic expression
D. Andergassen, C. Dotter, D. Wenzel, V. Sigl, P. Bammer, M. Muckenhuber, D. Mayer, T. Kulinski, H. Theussl, J. Penninger, C. Bock, D. Barlow, F. Pauler, Q. Hudson, ELife 6 (2017).
[Published Version] View | Files available | DOI
 
2017 | Published | Journal Article | IST-REx-ID: 1027 | OA
Toward a quantitative understanding of antibiotic resistance evolution
M. Lukacisinova, M.T. Bollenbach, Current Opinion in Biotechnology 46 (2017) 90–97.
[Published Version] View | Files available | DOI | WoS
 
2015 | Published | Journal Article | IST-REx-ID: 1619 | OA
Quantifying the determinants of evolutionary dynamics leading to drug resistance
G. Chevereau, M. Lukacisinova, T. Batur, A. Guvenek, D. Ayhan, E. Toprak, M.T. Bollenbach, PLoS Biology 13 (2015).
[Published Version] View | Files available | DOI
 
2015 | Published | Journal Article | IST-REx-ID: 1810 | OA
Antimicrobial interactions: Mechanisms and implications for drug discovery and resistance evolution
M.T. Bollenbach, Current Opinion in Microbiology 27 (2015) 1–9.
[Published Version] View | Files available | DOI
 
2015 | Published | Journal Article | IST-REx-ID: 1823 | OA
Systematic discovery of drug interaction mechanisms
G. Chevereau, M.T. Bollenbach, Molecular Systems Biology 11 (2015).
[Published Version] View | Files available | DOI
 

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