Microglia action towards neuronal circuit formation and function in health and disease
Project Period: 2017-05-01 – 2022-04-30
Funding Organisation:
EC/H2020
Acronym
MICROGLIA-CIRCUIT
Principal Investigator
Department(s)
Grant Number
715571
Funding Organisation
EC/H2020
7 Publications
2022 | Published | Journal Article | IST-REx-ID: 12244 | 
A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes
G. Colombo, R.J. Cubero, L. Kanari, A. Venturino, R. Schulz, M. Scolamiero, J. Agerberg, H. Mathys, L.-H. Tsai, W. Chachólski, K. Hess, S. Siegert, Nature Neuroscience 25 (2022) 1379–1393.
[Published Version]
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G. Colombo, R.J. Cubero, L. Kanari, A. Venturino, R. Schulz, M. Scolamiero, J. Agerberg, H. Mathys, L.-H. Tsai, W. Chachólski, K. Hess, S. Siegert, Nature Neuroscience 25 (2022) 1379–1393.
2022 | Published | Journal Article | IST-REx-ID: 11478 |
A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation
K. Bartalska, V. Hübschmann, M. Korkut, R.J. Cubero, A. Venturino, K. Rössler, T. Czech, S. Siegert, IScience 25 (2022).
[Published Version]
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K. Bartalska, V. Hübschmann, M. Korkut, R.J. Cubero, A. Venturino, K. Rössler, T. Czech, S. Siegert, IScience 25 (2022).
2022 | Published | Journal Article | IST-REx-ID: 12117 |
Assessing human iPSC-derived microglia identity and function by immunostaining, phagocytosis, calcium activity, and inflammation assay
V. Hübschmann, M. Korkut, S. Siegert, STAR Protocols 3 (2022).
[Published Version]
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V. Hübschmann, M. Korkut, S. Siegert, STAR Protocols 3 (2022).
2021 | Published | Journal Article | IST-REx-ID: 9642 |
Microglia enable mature perineuronal nets disassembly upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain
A. Venturino, R. Schulz, H. De Jesús-Cortés, M.E. Maes, B. Nagy, F. Reilly-Andújar, G. Colombo, R.J. Cubero, F.E. Schoot Uiterkamp, M.F. Bear, S. Siegert, Cell Reports 36 (2021).
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A. Venturino, R. Schulz, H. De Jesús-Cortés, M.E. Maes, B. Nagy, F. Reilly-Andújar, G. Colombo, R.J. Cubero, F.E. Schoot Uiterkamp, M.F. Bear, S. Siegert, Cell Reports 36 (2021).
2021 | Published | Journal Article | IST-REx-ID: 10565 |
Minimally invasive protocols and quantification for microglia-mediated perineuronal net disassembly in mouse brain
A. Venturino, S. Siegert, STAR Protocols 2 (2021).
[Published Version]
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A. Venturino, S. Siegert, STAR Protocols 2 (2021).
2021 | Published | Journal Article | IST-REx-ID: 10655 |
Optimizing AAV2/6 microglial targeting identified enhanced efficiency in the photoreceptor degenerative environment
M.E. Maes, G.M. Wögenstein, G. Colombo, R. Casado Polanco, S. Siegert, Molecular Therapy - Methods and Clinical Development 23 (2021) 210–224.
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M.E. Maes, G.M. Wögenstein, G. Colombo, R. Casado Polanco, S. Siegert, Molecular Therapy - Methods and Clinical Development 23 (2021) 210–224.
2019 | Published | Journal Article | IST-REx-ID: 6521 |
Targeting microglia with lentivirus and AAV: Recent advances and remaining challenges
M.E. Maes, G. Colombo, R. Schulz, S. Siegert, Neuroscience Letters 707 (2019).
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M.E. Maes, G. Colombo, R. Schulz, S. Siegert, Neuroscience Letters 707 (2019).